• Title/Summary/Keyword: Diffusion Strategy

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How to Combine Diffusion-Weighted and T2-Weighted Imaging for MRI Assessment of Pathologic Complete Response to Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer?

  • Jong Keon Jang;Chul-min Lee;Seong Ho Park;Jong Hoon Kim;Jihun Kim;Seok-Byung Lim;Chang Sik Yu;Jin Cheon Kim
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1451-1461
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    • 2021
  • Objective: Adequate methods of combining T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) to assess complete response (CR) to chemoradiotherapy (CRT) for rectal cancer are obscure. We aimed to determine an algorithm for combining T2WI and DWI to optimally suggest CR on MRI using visual assessment. Materials and Methods: We included 376 patients (male:female, 256:120; mean age ± standard deviation, 59.7 ± 11.1 years) who had undergone long-course CRT for rectal cancer and both pre- and post-CRT high-resolution rectal MRI during 2017-2018. Two experienced radiologists independently evaluated whether a tumor signal was absent, representing CR, on both post-CRT T2WI and DWI, and whether the pre-treatment DWI showed homogeneous hyperintensity throughout the lesion. Algorithms for combining T2WI and DWI were as follows: 'AND,' if both showed CR; 'OR,' if any one showed CR; and 'conditional OR,' if T2WI showed CR or DWI showed CR after the pre-treatment DWI showed homogeneous hyperintensity. Their efficacies for diagnosing pathologic CR (pCR) were determined in comparison with T2WI alone. Results: Sixty-nine patients (18.4%) had pCR. AND had a lower sensitivity without statistical significance (vs. 62.3% [43/69]; 59.4% [41/69], p = 0.500) and a significantly higher specificity (vs. 87.0% [267/307]; 90.2% [277/307], p = 0.002) than those of T2WI. Both OR and conditional OR combinations resulted in a large increase in sensitivity (vs. 62.3% [43/69]; 81.2% [56/69], p < 0.001; and 73.9% [51/69], p = 0.008, respectively) and a large decrease in specificity (vs. 87.0% [267/307]; 57.0% [175/307], p < 0.001; and 69.1% [212/307], p < 0.001, respectively) as compared with T2WI, ultimately creating additional false interpretations of CR more frequently than additional identification of patients with pCR. Conclusion: AND combination of T2WI and DWI is an appropriate strategy for suggesting CR using visual assessment of MRI after CRT for rectal cancer.

Prophylactic Uses of Probiotics as a Potential Alternative to Antimicrobials in Food Animals

  • Lee, Hyeon-Yong;Xu, Hua;Lee, Hak-Ju;Lim, Tae-Il;Choi, Young-Beom;Ko, Jeong-Rim;Ahn, Ju-Hee;Mustapha, Azlin
    • Food Science and Biotechnology
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    • v.17 no.1
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    • pp.191-194
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    • 2008
  • The antagonistic activity of probiotic strains (Bifidobacterium animalis BB-12, Bifidobacterium bifidum A, Bifidobacterium longum B6, Lactobacillus acidophilus ADH, Lactobacillus paracasei ATCC 25598, and Lactobacillus rhamnosus GG) against nalidixic acid resistant ($NA^R$) Escherichia coli O157:H7 MF1847, E. coli O157:H7 H2439, E. coli O157:H7 ATCC 43894, and E. coli O157:H7 C7927 was investigated using the agar-overlay, well diffusion, and broth culture tests. L. paracasei ATCC 25598 was the most effective probiotic strain in terms of in vitro antagonistic activity against $NA^R$ E. coli O157:H7, followed by L. rhamnosus GG, B. longum B6, and L. acidophilus ADH. The use of selected probiotic strains could be an effective pre-harvest intervention strategy to reduce the risk of $NA^R$ E. coli O157:H7 by maintaining a balanced microflora in animals and might provide many potential benefits in lieu of using antimicrobials.

An Inquiry into Agricultural Development Theory (1) - Fei-Ranis's Historical Approach and its Relevance to Less Developed World - (농업발전(農業發展) 이론연구(理論硏究) (I) - Fei-Ranis의 경제사적(經濟史的) 접근방법(接近方法)을 중심(中心)으로 -)

  • Lee, Ho Chol
    • Current Research on Agriculture and Life Sciences
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    • v.1
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    • pp.239-253
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    • 1983
  • This study attempted to introduce Fei-Ranis's agricultural development theory and discuss its problem for the rural development of less developed world. Fei-Ranis systematized the development process of Western European economy on the ground of dualism. They divided the process into 4 stages by the concept of 'mode of operation'. Paticularly, they consider agrarian mercantilism as take-off stage and its development were achieved by the increase of trade margin and labor productivity. Especially, they thought that only agricultural revolution through the diffusion of internal exchange economy and construction of tree-star system can accomplish favorable transition to industrial capitalism. In order to promote this agricultural development, less developed world must abolish short-run agricultural policy and propel 'learning by the contact' strategy through 'tree-star system' and 'parellel development.' In reality, it was problematic that the contemporary less developed world is trying, in the course of a few decades, to imitate Western European experience with development over the last four centuries. But Fei-Ranis ignored qualitative aspects of agricultural development by tree-star system and also it is criticized that they considered agricultural development process of less developed world follows only that of Western European classical process.

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Networked Creativity on the Censored Web 2.0: Chinese Users' Twitter-based Activities on the Issue of Internet Censorship

  • Xu, Weiai Wayne;Feng, Miao
    • Journal of Contemporary Eastern Asia
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    • v.14 no.1
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    • pp.23-43
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    • 2015
  • In most of the world, the current trend in information technology is for open data movement that promotes transparency and equal access. An opposite trend is observed in China, which has the world's largest Internet population. The country has implemented sophisticated cyber-infrastructure and practices under the name of The Golden Shield Project (commonly referred to as the Great Firewall) to limit access to popular international web services and to filter traffic containing 'undesirable' political content. Increasingly, tech-savvy Chinese bypass this firewall and use Twitter to share knowledge on censorship circumvention and encryption to collectively troubleshoot firewall evasion methods, and even mobilize actions that border on activism. Using a mixed mythological approach, the current study addresses such networked knowledge sharing among citizens in a restricted web ecosystem. On the theoretical front, this study uses webometric approaches to understand change agents and positive deviant in the diffusion of censorship circumvention technology. On policy-level, the study provides insights for Internet regulators and digital rights groups to help best utilize communication networks of positive deviants to counter Internet control.

Antiblurry Dejitter Image Stabilization Method of Fuzzy Video for Driving Recorders

  • Xiong, Jing-Ying;Dai, Ming;Zhao, Chun-Lei;Wang, Ruo-Qiu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.6
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    • pp.3086-3103
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    • 2017
  • Video images captured by vehicle cameras often contain blurry or dithering frames due to inadvertent motion from bumps in the road or by insufficient illumination during the morning or evening, which greatly reduces the perception of objects expression and recognition from the records. Therefore, a real-time electronic stabilization method to correct fuzzy video from driving recorders has been proposed. In the first stage of feature detection, a coarse-to-fine inspection policy and a scale nonlinear diffusion filter are proposed to provide more accurate keypoints. Second, a new antiblurry binary descriptor and a feature point selection strategy for unintentional estimation are proposed, which brought more discriminative power. In addition, a new evaluation criterion for affine region detectors is presented based on the percentage interval of repeatability. The experiments show that the proposed method exhibits improvement in detecting blurry corner points. Moreover, it improves the performance of the algorithm and guarantees high processing speed at the same time.

A Case Study on the Changing Aspects of Modern Fashion Trend System (현대 패션 트렌드 시스템의 변화 양상에 대한 사례연구)

  • Kim, Sung Eun;Ha, Jisoo
    • Journal of the Korean Society of Clothing and Textiles
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    • v.42 no.4
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    • pp.708-725
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    • 2018
  • The advancement of digital technology has made changes in the fashion system and trend development process inevitable. This article clarifies changes in the modern fashion industry system and the causes of comprehensive changes that result from the development of digital technology. The methodology of this study is based on literature and case studies based on the information magazine most used by fashion industry workers. This study classifies fashion systems into 5 types and 14 types in detail. The study results indicate the way to change the fashion style trend schedule per year, fast/ultrafast fashion system, fashion rental system, DTC system and change of fashion system by consumer participation. The causes of the changes in fashion system are indicated that an increase of trend sensitivity due to an increase in the diffusion rate of information, expansion of expression of personality through digital network, increase of possibility of grouping of small number of tastes and change of prosumer possible changes in the environment. This study provides basic data on fashion system research and the construction of an appropriate response strategy for a changing environment.

Analysis of Factors Affecting Intention of Continuous Use for Mobile Wallet Based on the Information System Success Model (정보시스템 성공모형을 기반으로 한 모바일월렛 지속사용의도에 미치는 영향 요인 분석)

  • Jeon, Sun-Ho;Kang, Ju-Young;Lim, Jay-Ick
    • Journal of Information Technology Services
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    • v.13 no.4
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    • pp.325-340
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    • 2014
  • Mobile payment system using NFC attracted attention as the mobile payment market grows due to the fast diffusion of smart phones. However, non NFC mobile payment recently appeared because of the slow growth of infrastructure for NFC. With advent of Non NFC mobile payment applications, mobile payment industry is in developing trend. Non NFC mobile payment revitalizes the market by overcoming the limit of NFC with the smart applications using bar code and QR code payment, and providing various discounts, membership benefits and payment information. Therefore, this paper analyzed the intention of continuous use with the quality of mobile payment application based on the information system success model. Three categories of factors which are system quality, service quality, and information quality were used. We verified the significance of the factors affecting the intension of continuous use. mainly, quality of information was considered as an important factor of continuous Intention to Use. Also, unlike previous NFC, it was found that in Non-NFC, compatibility might not be as important factor. Moreover, we suggest a marketing strategy of companies for mobile payment industry which focus on information quality. and future research directions for non NFC payment market.

Antimicrobial Activity of the Scolopendrasin V Peptide Identified from the Centipede Scolopendra subspinipes mutilans

  • Lee, Joon Ha;Kim, In-Woo;Kim, Mi-Ae;Ahn, Mi-Young;Yun, Eun-Young;Hwang, Jae Sam
    • Journal of Microbiology and Biotechnology
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    • v.27 no.1
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    • pp.43-48
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    • 2017
  • In a previous study, we analyzed the transcriptome of Scolopendra subspinipes mutilans using next-generation sequencing technology and identified several antimicrobial peptide candidates. One of the peptides, scolopendrasin V, was selected based on the physicochemical properties of antimicrobial peptides using a bioinformatics strategy. In this study, we assessed the antimicrobial activities of scolopendrasin V using the radial diffusion assay and colony count assay. We also investigated the mode of action of scolopendrasin V using flow cytometry. We found that scolopendrasin V's mechanism of action involved binding to the surface of microorganisms via a specific interaction with lipopolysaccharides, lipoteichoic acid, and peptidoglycans, which are components of the bacterial membrane. These results provide a basis for developing peptide antibiotics.

Emerging Gender Issues in Korean Online Media: A Temporal Semantic Network Analysis Approach

  • Lee, Young-Joo;Park, Ji-Young
    • Journal of Contemporary Eastern Asia
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    • v.18 no.2
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    • pp.118-141
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    • 2019
  • In South Korea, as awareness of gender equality increased since the 1990s, policies for gender equality and social awareness of equality have been established. Until recently, however, the gap between men and women in social and economic activities has not reached the globally desired level and led to social conflict throughout the country. In this study, we analyze the content of online news comments to understand the public perception of gender equality and the details of gender conflict and to grasp the emergence and diffusion process of emerging issues on gender equality. We collected text data from the online news that included the word 'gender equality' posted from January 2012 to June 2017 and also collected comments on each selected news item. Through text mining and the temporal semantic network analysis, we tracked the changes in discourse on gender equality and conflict. Results revealed that gender conflicts are increasing in the online media, and the focus of conflict is shifting from 'position and role inequality' to 'opportunity inequality'.

The Study of Online Marketing's Impact of Food Service Companies on the Purchasing Behavior Itself and Brand Recognition of New Brand of Menu : Focusing on Viral Marketing (외식기업의 온라인 마케팅을 통한 외식메뉴 구매형태 및 신규브랜드 인식에 관한 연구 : 바이럴마케팅을 중심으로)

  • Kang, Byong-Nam;Moon, Sung-Sik
    • Culinary science and hospitality research
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    • v.23 no.8
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    • pp.173-183
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    • 2017
  • The purpose of this study is to investigate the causal relationship between new brand awareness and new brand awareness according to type of restaurant menu purchase information. This study will provide basic research data on viral marketing strategy through online marketing of restaurant companies. The purpose of this study is to investigate the effect of information obtained through blog information and SNS advertisement on word effect (information acceptance and information transfer) and to investigate the effect of word of mouth effect on consumers' purchase intention. A total of 206 samples were used for this analysis and regression analysis was performed using SPSS 18.0. The results of the study are as follows. First, experience type, timely relevance and consensus among the characteristics of blog information affect information acceptance. Experience, and accuracy are affecting information delivery. Second, information discomfort among the characteristics of SNS advertising information influences the acceptance of information. Information, entertainment and trust are affecting information dissemination. Third, information acceptance and information diffusion affect purchase intention.