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Antimicrobial Activity Screening of Sixty-four Evergreen Woody Species According to Extraction Conditions against Trichophyton mentagrophytes (상록성 목본 64종의 추출조건에 따른 무좀원인균의 항균활성 스크리닝)

  • Jang, Bo Kook;Chi, Lai Won;Cho, Ju Sung;Lee, Cheol Hee
    • Korean Journal of Plant Resources
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    • v.31 no.4
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    • pp.330-341
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    • 2018
  • This study was performed to investigate and measure the antimicrobial activity of evergreen woody species extracts on Trichophyton mentagrophytes. To do this, leaves and stems were collected from Wando and Jeju islands, and were used for the extraction with different solvents (i.e., distilled water, 80% ethanol, and 100% methanol), and at different ultrasonic extracting times (i.e., 15, 30, and 45 minutes). The experiment was conducted by using the agar diffusion method. The clear zone was measured after incubating the paper disc containing the plant extract in a bacterial culture medium. The controls were synthetic antimicrobials, methylparaben and phenoxyethanol, at concentrations of 0.4, 1, 2, and 4 mg/disc. Altogether, extracts of 56 out of 64 species used in this study had inhibitory activity, which confirmed their antimicrobial activity against Athlete's foot. Among them, the crude ethanolic extract of Elaeocarpus sylvestris in 45 min showed a zone of inhibition < 20.2 mm, while the clear zone of Actinodaphne lancifolia ethanolic extraction for 30 min was 23.5 mm. Also, Quercus acuta, Dendropanax morbiferus and Daphne odora showed clear zones of 28.0 mm (45 minutes ethanolic extraction), 20.5 mm (45 minutes crude methanolic extraction) and 19.7 mm (45 minutes methanolic extraction), respectively. Thus, these results confirm that the extracts of evergreen woody species have therapeutic potential against Athlete's foot, and suggest that in order to extract adequate amounts of antimicrobial substance from the plant sources, ideal extraction condition has to be considered.

Simulation study on effects of loading rate on uniaxial compression failure of composite rock-coal layer

  • Chen, Shao J.;Yin, Da W.;Jiang, N.;Wang, F.;Guo, Wei J.
    • Geomechanics and Engineering
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    • v.17 no.4
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    • pp.333-342
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    • 2019
  • Geological dynamic hazards during coal mining can be caused by the failure of a composite system consisting of roof rock and coal layers, subject to different loading rates due to different advancing velocities in the working face. In this paper, the uniaxial compression test simulations on the composite rock-coal layers were performed using $PFC^{2D}$ software and especially the effects of loading rate on the stress-strain behavior, strength characteristics and crack nucleation, propagation and coalescence in a composite layer were analyzed. In addition, considering the composite layer, the mechanisms for the advanced bore decompression in coal to prevent the geological dynamic hazards at a rapid advancing velocity of working face were explored. The uniaxial compressive strength and peak strain are found to increase with the increase of loading rate. After post-peak point, the stress-strain curve shows a steep stepped drop at a low loading rate, while the stress-strain curve exhibits a slowly progressive decrease at a high loading rate. The cracking mainly occurs within coal, and no apparent cracking is observed for rock. While at a high loading rate, the rock near the bedding plane is damaged by rapid crack propagation in coal. The cracking pattern is not a single shear zone, but exhibits as two simultaneously propagating shear zones in a "X" shape. Following this, the coal breaks into many pieces and the fragment size and number increase with loading rate. Whereas a low loading rate promotes the development of tensile crack, the failure pattern shows a V-shaped hybrid shear and tensile failure. The shear failure becomes dominant with an increasing loading rate. Meanwhile, with the increase of loading rate, the width of the main shear failure zone increases. Moreover, the advanced bore decompression changes the physical property and energy accumulation conditions of the composite layer, which increases the strain energy dissipation, and the occurrence possibility of geological dynamic hazards is reduced at a rapid advancing velocity of working face.

Top shoes foot pressure basis of the comparison analysis combine conical top foundation walking upon ground conditions (보행시 지반조건에 따른 팽이기초를 접목시킨 신발 족저압 분포 비교분석)

  • Kim, Yeon-Deok;Kim, Seg-Jin;Min, Byeong-Heon;Kim, Sang-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.20-28
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    • 2019
  • This study comparatively analyzes general walking shoes on the conical top foundation of the ground condition and the pressure distribution during walking with shoes that are currently under development. Two categories of footwear were used: general footwear and a footwear conical top foundation that is currently under development. Experiments were carried out on hard ground and sandy soil in 15 male twenties that satisfy the conditions of normal foot wearing 260 mm. The pressure during walking was measured using Techstorm's Wireless Insole System, and foot pressure was measured in 7 zones of the foot. Studies have shown different maximum forces, average pressures, and pressure distributions depending on the shoe and ground conditions. This study shows that shoes with general low pressure dispersion effects depending on the feet in hard ground and sand ground are different from shoes with the conical top foundation that is currently under development. It is expected that it will be useful for the development of shoes that can be worn in all hard ground and sandy ground by selecting various rubber materials through further research.

A Study on Conservation and Desalination for Iron Weapons During the Korean War from DMZ (비무장지대 한국전쟁 전사자 유해발굴 수습 철제 총기류의 보존처리와 탈염처리 방법 고찰)

  • Jo, Ha Nui;Nam, Do Hyeon;Kim, Mi Hyun;Lee, Jae Sung
    • Journal of Conservation Science
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    • v.37 no.6
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    • pp.821-830
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    • 2021
  • The weapons excavated from the de-militarized zones (DMZ) of Korea are vulnerable to corrosion due to the immediate and drastic environmental change. Especially, the chloride ions (Cl-) in iron weapons cause active corrosion and require removal. In this study, conservation treatment and de-salination was performed for the discovered weapons from excavation sites of soldiers killed in action during the Korean War. Furthermore, an attempt was made to prepare the most stable plan for conservation treatment through the comparative study of soaking weapons in distilled water without chemicals and in a solution of sodium (SSC) at different temperatures. In the preliminarily experiments, the comparison of the eluted Cl- ions according to different conditions of de-salination showed that the highest number of ions were detected from the de-salination with SSC at a temperature of 100℃, and its duration was much smaller, i.e., 1~2 weeks. Accordingly, for the parts from the guns and rifles amongst other objects, a six-time de-salination was conducted in the SSC solution for 8 hours at 100℃ and subsequently, for 16 hours at room temperature during which the distilled water and SSC were exchanged every week. However, in the case of a loaded rifle, the de-salination was not conducted, considering the risk that the high temperature and pressure by impregnation in vacuum could cause an explosion

Comparison Analysis of the Road Environment between Urban and Suburban Area for Connected and Automated Driving(CAD) Mobility Services (교통소외지역 자율주행 모빌리티 서비스를 위한 도로 환경 분석 : 대구광역시와 세종특별자치시를 중심으로)

  • Kim, Ahreum;Woo, Boram;Tak, Sehyun;Lim, Seohyun
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.5
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    • pp.287-300
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    • 2022
  • The introduction of Connected and Automated(CAD) technology has a growing interests especially in areas with low demand for transport, where often the local transport services do not connect to peripheral areas for more efficient and convenient mobility services. However, there are few researches on CAD-based mobility services in areas with low demand for transport. Because current researches are mainly focuses on introduction of CAD-based mobility services in area with high demand for transport such as urban and highway. These two areas have different road environments and these differences require different driving technology especially related to Operational Design Domain(ODD). ODD is important factors for introduction of CAD-based mobility services. Therefore, we compare the road environments of areas with low demand for transport and areas with high demand for transport in terms of ODD. In addition, this paper proposes suggest guidance for the introduction of CAD-based mobility services in areas with low demand for transport such as rural and suburban areas.

Development and Application of a Mountain Village Revitalization Index Using Big Data (빅데이터를 활용한 산촌 활성화 지수 개발 및 적용)

  • Jang-Hwan Jo;Kyu-Dong Lee;Hye-Jung Cho;Sungki Jun;GwanPyeong Roh;Eunseok Jang
    • Journal of Korean Society of Forest Science
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    • v.113 no.3
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    • pp.292-307
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    • 2024
  • This study aimed to develop an index to assess the level of revitalization in mountain villages by utilizing big data and to verify its applicability in such areas. To achieve this, four key indices related to mountain villages were developed to evaluate the degree of revitalization, namely, Settlement Index, Workplace Index, Learning Index, and Leisure Index. These indices enable users to compare the revitalization levels of different mountain villages by establishing living zones, assigning data weights, extracting comparative data, and generating results in both map and report formats. The revitalization index developed in this study was applied to five mountain villages (A, B, C, D, E) located in Jeollabuk-do. Results showed that Village C had the highest comprehensive score of 320 points, while Village E had the lowest score of 141 points. In the mountain village indices of Jeollabuk-do, the Workplace Index generally showed higher scores, whereas the Learning Index had relatively lower scores on average. The development of these indices provides a practical means to identify which areas should be prioritized for support to enhance revitalization in specific mountain villages and offers a clear comparison of the revitalization levels across different regions and individual villages. The mountain village revitalization index developed in this study is expected to serve as valuable foundational information for formulating mountain village revitalization policies.

Aviation Safety Regulation and ICAO's Response to Emerging Issues (항공안전규제와 새로운 이슈에 대한 ICAO의 대응)

  • Shin, Dong-Chun
    • The Korean Journal of Air & Space Law and Policy
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    • v.30 no.1
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    • pp.207-244
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    • 2015
  • Aviation safety is the stage in which the risk of harm to persons or of property damage is reduced to, and maintained at or below, an acceptable level through a continuing process of hazard identification and risk management. Many accidents and incidents have been taking place since 2014, while there had been relatively safer skies before 2014. International civil aviation community has been exerting great efforts to deal with these emerging issues, thus enhancing and ensuring safety throughout the world over the years. The Preamble of the Chicago Convention emphasizes safety and order of international air transport, and so many Articles in the Convention are related to the safety. Furthermore, most of the Annexes to the Convention are International Standards and Recommended Practices pertaining to the safety. In particular, Annex 19, which was promulgated in Nov. 2013, dealing with safety management system. ICAO, as law-making body, has Air Navigation Commission, Council, Assembly to deliberate and make decisions regarding safety issues. It is also implementing USOAP and USAP to supervise safety functions of member States. After MH 370 disappeared in 2014, ICAO is developing Global Tracking System whereby there should be no loophole in tracking the location of aircraft anywhere in world with the information provided by many stakeholders concerned. MH 17 accident drove ICAO to install web-based repository where information relating to the operation in conflict zones is provided and shared. In addition, ICAO has been initiating various solutions to emerging issues such as ebola outbreak and operation under extreme meteorological conditions. Considering the necessity of protection and sharing of safety data and information to enhance safety level, ICAO is now suggesting enhanced provisions to do so, and getting feedback from member States. It has been observed that ICAO has been approaching issues towards problem-solving from four different dimensions. First regarding time, it analyses past experiences and best practices, and make solutions in short, mid and long terms. Second, from space perspective, ICAO covers States, region and the world as a whole. Third, regarding stakeholders it consults with and hear from as many entities as it could, including airlines, airports, community, consumers, manufacturers, air traffic control centers, air navigation service providers, industry and insurers. Last not but least, in terms of regulatory changes, it identifies best practices, guidance materials and provisions which could become standards and recommended practices.

Inferring the Transit Trip Destination Zone of Smart Card User Using Trip Chain Structure (통행사슬 구조를 이용한 교통카드 이용자의 대중교통 통행종점 추정)

  • SHIN, Kangwon
    • Journal of Korean Society of Transportation
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    • v.34 no.5
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    • pp.437-448
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    • 2016
  • Some previous researches suggested a transit trip destination inference method by constructing trip chains with incomplete(missing destination) smart card dataset obtained on the entry fare control systems. To explore the feasibility of the transit trip destination inference method, the transit trip chains are constructed from the pre-paid smart card tagging data collected in Busan on October 2014 weekdays by tracing the card IDs, tagging times(boarding, alighting, transfer), and the trip linking distances between two consecutive transit trips in a daily sequences. Assuming that most trips in the transit trip chains are linked successively, the individual transit trip destination zones are inferred as the consecutive linking trip's origin zones. Applying the model to the complete trips with observed OD reveals that about 82% of the inferred trip destinations are the same as those of the observed trip destinations and the inference error defined as the difference in distance between the inferred and observed alighting stops is minimized when the trip linking distance is less than or equal to 0.5km. When applying the model to the incomplete trips with missing destinations, the overall destination missing rate decreases from 71.40% to 21.74% and approximately 77% of the destination missing trips are the single transit trips for which the destinations can not be inferable. In addition, the model remarkably reduces the destination missing rate of the multiple incomplete transit trips from 69.56% to 6.27%. Spearman's rank correlation and Chi-squared goodness-of-fit tests showed that the ranks for transit trips of each zone are not significantly affected by the inferred trips, but the transit trip distributions only using small complete trips are significantly different from those using complete and inferred trips. Therefore, it is concluded that the model should be applicable to derive a realistic transit trip patterns in cities with the incomplete smart card data.

Automatic Interpretation of Epileptogenic Zones in F-18-FDG Brain PET using Artificial Neural Network (인공신경회로망을 이용한 F-18-FDG 뇌 PET의 간질원인병소 자동해석)

  • 이재성;김석기;이명철;박광석;이동수
    • Journal of Biomedical Engineering Research
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    • v.19 no.5
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    • pp.455-468
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    • 1998
  • For the objective interpretation of cerebral metabolic patterns in epilepsy patients, we developed computer-aided classifier using artificial neural network. We studied interictal brain FDG PET scans of 257 epilepsy patients who were diagnosed as normal(n=64), L TLE (n=112), or R TLE (n=81) by visual interpretation. Automatically segmented volume of interest (VOI) was used to reliably extract the features representing patterns of cerebral metabolism. All images were spatially normalized to MNI standard PET template and smoothed with 16mm FWHM Gaussian kernel using SPM96. Mean count in cerebral region was normalized. The VOls for 34 cerebral regions were previously defined on the standard template and 17 different counts of mirrored regions to hemispheric midline were extracted from spatially normalized images. A three-layer feed-forward error back-propagation neural network classifier with 7 input nodes and 3 output nodes was used. The network was trained to interpret metabolic patterns and produce identical diagnoses with those of expert viewers. The performance of the neural network was optimized by testing with 5~40 nodes in hidden layer. Randomly selected 40 images from each group were used to train the network and the remainders were used to test the learned network. The optimized neural network gave a maximum agreement rate of 80.3% with expert viewers. It used 20 hidden nodes and was trained for 1508 epochs. Also, neural network gave agreement rates of 75~80% with 10 or 30 nodes in hidden layer. We conclude that artificial neural network performed as well as human experts and could be potentially useful as clinical decision support tool for the localization of epileptogenic zones.

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A Study on Designation Potential as Ramsar Site and Management Method of Massive Scale of Wetland - A Case of Jang Hang Estuary Wetland, Han River, Korea - (대규모 습지의 Ramsar Site 지정 가능성 검토 및 관리방안 연구 - 한강하류 장항습지를 대상으로 -)

  • Yeum, Jung-Hun;Han, Bong-Ho;Lee, Kyong-Jae
    • Korean Journal of Environment and Ecology
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    • v.24 no.3
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    • pp.249-257
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    • 2010
  • The purpose of this paper is to weigh the possibility of endangered Jang-hang wetland at the estuary of Han River to be included on the Ramsar List of Wetlands of International Importance and come up with ways to manage the wetland depending on its biotope patterns. The target area is located between Gimpo bridge and Isanpo I.C. with about $2.7km^2$ area. Through the analysis of RIS(Information Sheet for Ramsar Wetlands), it was known that the wetland is located on the sedimentary topography and formed as a result of sediment at the estuary of the river owing to the concentration of rainfall during summer. The vegetation environment in the area is divided into brackish water and fresh water areas depending on salinity. Rhizosphere soil(RS) of the area was analyzed to be Silt loam while bottom RS to be Sand loam. The plant ecology was composed of 52 families 135 species and 11 varieties and 146 types. Among indigenous species found are Salix koreensis, Phragmites communis and Miscanthus sacchariflorus. The analyzed results of the actual vegetation showed that willow community accounts for 37% of the area and rice field is 13.5%. As for animal ecology, total of 62 species and 25,977 individual wild birds were observed. After comparing and analyzing the RIS we compiled with the Ramsar Site designation standards, it turns out that the Jang-hang wetland meets criteria 1(biographic region), criteria 2,3 and 4(species and ecological communities) and criteria 5 and 6(water birds). Thus, Jang-hang wetland is eligible for the Ramsar site. As a result of establishing and evaluating the biotope types for setting management areas, Jang-hang wetland has a total of 13 different types, and the grade I represents 75.4% of the area while the grade III 0.8% of the land status. We categorized four management zones for the wetland depending on the biotope patterns - preservation, restoration, use and buffer zones and suggested management methods for each zone.