• 대한간호학회지
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• 제43권6호
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• pp.746-759
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• 2013

Purpose: Infrared thermometers are increasingly used as a convenient, non-invasive assessment method for febrile children. However, the diagnostic accuracy of the infrared thermometer for children has been questioned, particularly in relation to sensitivity and specificity. The aim of this study was to evaluate diagnostic accuracy of infrared thermometers in febrile children. Methods: Articles published between 1966 and 2012 from periodicals indexed in the Ovid Medline, Embase, CINAHL, Cochrane, KoreaMed, NDSL, KERIS and other databases were selected, using the following keywords: 'infrared thermometer'. The QUADAS-II was applied to assess the internal validity of the diagnostic studies. Selected studies were analyzed using meta-analysis with MetaDisc 1.4. Results: Nineteen diagnostic studies with high methodological quality, involving 4,304 children, were included. The results of meta-analysis showed that the pooled sensitivity, specificity and AUC (Area Under the Curve) of infrared tympanic thermometers in children over 1 year were 0.80 (95% CI 0.78, 0.81), 0.94 (95% CI 0.93, 0.95) and 0.95 respectively. However the diagnostic accuracy of infrared tympanic thermometers in children with hyperthermia was low. Conclusion: The diagnostic accuracy of infrared tympanic thermometer was similar to axillary and rectal thermometers indicating a need for further research to substantiate these findings in children with hyperthermia.

• 대한핵의학회지
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• 제27권2호
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• pp.195-202
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• 1993

$^{123}Iodine$-metaiodobenzylguanidine (MIBG) which is a norepinephrine analogue, can be used to evaluate the sympathetic innervation of the heart. In this study, cardiac imaging with $^{123}I-MIBG$ was performed in patients with 9 dilated cardiomyopathy, 2 ischemic cardiomyopathy and 1 acute myocardial infarction to evaluate the sympathetic nervous function. $^{123}I-MIBG$ imaging showed multifocal defects (8), diffuse defect (2), near non-visualization (2). The defects of MIBG scans were found to be larger and more severe on 4 hours image than 30 minutes. Heart to lung, heart to mediastinum ratios were decreased at 4 hours than those at 30 minutes. Measured LVEF values were not correlated with the severity of MIBG uptake. $^{99m}Tc-MIBI$ imaging was also performed in all patients to find the relationship with $^{123}I-MIBG$ scan. $^{99m}Tc-MIBI$ scan showed multifocal defects in 9 patients, diffuse defects in 1 patient and no defect in 2 patients. The defects are similar in size, severity and extent, but more larger and severe on $^{123}I-MIBG$ imaging. Therefore, cardiac $^{123}I-MIBG$ imaging is a useful method to evaluate the sympathetic nervous function in cardiomyopathy.

• 산업경영시스템학회지
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• 제36권3호
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• pp.109-117
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• 2013

This study designed a "Diagnostic Model for Management Innovation of Medium Enterprises" based on the theoretical background of success factor and management diagnosis model for management innovation of medium enterprises and suggested a measure for utilization of strategic subject and diagnostic model that enterprises can apply. Utilization of medium enterprises management innovation diagnostic model designed through this study would be of help for making a diagnosis of the capability maturity level of enterprises' current management system and improving it by establishing a challenging capability objective and building a circulation system capable of innovating enterprises. It is expected for enterprises to overcome growing pains and establish a management system capable of achieving outcome (productivity) by repeating measurement and innovation through management diagnosis. In addition, this study provides a method to produce a strategic subject, select priority of implementation and prepare an implementation road map by classifying and filtering management issues produced as a result of management diagnosis in a systematic way. If variables necessary for production of an objective weighted value of scoring and discover of elements for category of diagnostic model and elementary items as well as design of a self-diagnosis questionnaire, measurement of management outcome suggested in this study can be able to be verified and supplemented through case study in the future, it is expected to make the degree of completion as a diagnostic model elevated that may help for growth and development through innovation of medium enterprises.

• 대한한방부인과학회지
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• 제30권3호
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• pp.65-78
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• 2017

Objectives: This study was aimed to develop a guideline for the application of diagnostic devices for menopausal syndrome. Methods: We conducted a literature review and a questionnaire survey on diagnostic devices including Digital Infrared Thermal Imaging (DITI), pulse diagnosis device, Heart Rate Variability (HRV), body composition analyzer, Yangdorak. Results: We retrieved some clinical values for usage of devices from the articles. Especially, DITI was useful to identify the pattern of body temperature distribution. The respondents answered that they diagnosed menopausal syndrome by using body composition analyzer (62.3%), DITI (60%), HRV (60%), pulse diagnosis device (45.7%), Yangdorak (34.3%). The respondents answered that they don't use diagnostic devices when they diagnosed menopausal syndrome because of absence of device, cost, difficulty of interpretation, substitution of another diagnostic method. After experts survey, it was recommended to use DITI, HRV, body composition analyzer. There was no consensus on the use of pulse diagnosis device, Yangdorak in diagnosing menopausal syndrome. Conclusions: We developed a guideline for the application of diagnostic devices for menopausal syndrome.

• 대한한의진단학회지
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• 제20권1호
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• pp.37-44
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• 2016

Ultrasonic imaging is the most widely modality among modern imaging device for medical diagnosis. Nevertheless, medical ultrasound images suffer from speckle noise and low contrast. In this paper, we propose probabilistic edge map for ultrasound image edge enhancement using automatic alien algorithm. The proposed method used applied speckle reduced ultrasound imaging for edge improvement using sequentially acquired ultrasound imaging. To evaluate the performance of method, the similarity between the reference and edge enhanced image was measured by quantity analysis. The experimental results show that the proposed method considerably improves the image quality with region edge enhancement.

• Journal of Acupuncture Research
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• 제18권4호
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• pp.91-100
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• 2001

Background and Objective : Most diagnostic method for numbness were invasive and complex. So we need to simplify and objectify diagnostic method for numbness. Some study with EAV which is one of Physiological Signal Measuring Instruments, report significantly result as objective diagnostic method for other clinical symptom. By using EAV, we have obtained some physiological signal data from meridian-acupoints of 58 numbness cases. Objective and Methods : This study researched into the clinical statistics for 58 case who ware in numbness, and they ware treated with oriental medical care at the Dong-shin university oriental hospital during 1 year from April 3 2000 to March 30 2001. The data were analyzed and interpreted to compare with traditional differentiation of symptom-complexes, then further evaluated as the Five Evolutive Phases to make them differentiated. The EAV valus of Five Evolutive Phases were identified with the sequence of wood(木), fire(火), earth(土), steel(金), water(水). Results and Conclusion : These values of physiological signal were identical with standard differentiation of symptom-complexes of numbness which is the main cause of dishannonious flow of Qi and blood of the in the liver and deficiency of Qi and blood of the bladder with stagnancy of dampness. Among Five Evolutive Phases, Earth and wood values were increased, steel, fire and water were decreased significantly. This data imply the possibility of somewhat generalization from measuring instruments.

• 한국지하수토양환경학회지:지하수토양환경
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• 제21권4호
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• pp.1-9
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• 2016

Rehabilitation for low-yielding wells resulting in improvement on groundwater quantity and quality is considered to be the most economic and ecofriendly method against the increasing demand to groundwater due to frequent drought and the increase in numbers of agricultural complex for growing horticultural crops. This study suggests standard, stepwise diagnostic fuctions consisting of four steps (Basic inspection, Specific inspection, Rehabilitation, and Management) for an optimal management to the wells. Basic inspection can provide information on current groundwater quantity and quality compared with those on its initial stage. Specific-inspection based on hydrogeology can scientifically demonstrate causes of deterioration on groundwater quantity and quality. Results of specific inspection can suggest an optimal rehabilitation method to solve deteriorating problems including clogging and corrosion for the wells. After rehabiliating the wells, an assessment on groundwater quantity and quality would be conducted to identify the suitability of the applied method and improvement of the wells. A short-term, periodic management to the wells is considered as the key to save a public management budget. Suggested diagnostic functions can possibly induce sustainable supply of agricultural groundwater to the farm land and finally contribute the increase on rural household income.

• Parasites, Hosts and Diseases
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• 제52권4호
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• pp.377-381
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• 2014

Microscopy is considered as the gold standard for malaria diagnosis although its wide application is limited by the requirement of highly experienced microscopists. PCR and serological tests provide efficient diagnostic performance and have been applied for malaria diagnosis and research. The aim of this study was to investigate the diagnostic performance of nested PCR and a recently developed an ELISA-based new rapid diagnosis test (RDT), NovaLisa test kit, for diagnosis of malaria infection, using microscopic method as the gold standard. The performance of nested-PCR as a malaria diagnostic tool is excellent with respect to its high accuracy, sensitivity, specificity, and ability to discriminate Plasmodium species. The sensitivity and specificity of nested-PCR compared with the microscopic method for detection of Plasmodium falciparum, Plasmodium vivax, and P. falciparum/P. vivax mixed infection were 71.4 vs 100%, 100 vs 98.7%, and 100 vs 95.0%, respectively. The sensitivity and specificity of the ELISA-based NovaLisa test kit compared with the microscopic method for detection of Plasmodium genus were 89.0 vs 91.6%, respectively. NovaLisa test kit provided comparable diagnostic performance. Its relatively low cost, simplicity, and rapidity enables large scale field application.

• 대한수의학회지
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• 제39권1호
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• pp.118-125
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• 1999

Porcine Proliferative Enteropathy(PPE) is an infectious enteric disease and a major cause of economic loss in swine industry due to weight loss, poor growth and sudden death in growing and finishing pigs at 6 to 20 weeks of age. PPE has been diagnosed by clinical signs, syndrom and lesions in the intestine in Korea. However, the diagnostic method had several problems in the detection of infected or carrier pigs. Therefore, in this study, we established the polymerase chain reaction(PCR) which was a fast, specific and sensitive method for identification of Lawsonia intracellularis (L intracellularis). We designed and synthesized primer on the 16S rDNA and p78 gene encoding L intracellularis. Specificity of the method was confirmed by comparison of the PCR results using other enteric bacteria and the study has shown that PCR method was sensitive to detect 1ng of genomic DNA as a template. Identity of the PCR products was confirmed by comparison of pattern of restriction endonuclease analysis with restriction enzyme Hae III and Pst I. Also, the PCR method was applicable to the naturally affected pigs with PPE. Based on the results from this study, the PCR method could be used as a fast and specific diagnostic tool for PPE.

• 대한임상검사과학회지
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• 제51권4호
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• pp.414-419
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• 2019

JC polyomavirus (JCPyV)는 viral group I, Polyomaviridae로 분류되는 사람 병원성 바이러스 이다. JCPyV는 최근 하수 등 수질오염 지표로 제안됨에 따라 수질환경에서 모니터링 필요성이 제기되고 있다. 임상 및 환경 시료 중 JCPyV 검출을 위해서 PCR 시스템이 사용되어 왔다. 그러나 신속하고 높은 검출 민감도를 가진 방법의 필요성에 따라 이번 연구에서는 등온증폭 프라이머 조합을 개발하였다. 이번에 개발한 방법은 기존 PCR 시스템에 비해 더욱 신속 및 약 10배 더 높은 검출 민감도를 보여주었다. 또한 본 연구에서 개발한 검출 방법의 재 검정을 위해서 HaeIII 제한효소를 이용한 방법을 함께 고안하였다. 따라서 이번 연구는 임상, 환경 등의 시료에서 JCPyV를 모니터링 하기 위한 방법으로 활용이 기대된다.