• Genomics & Informatics
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• v.16 no.4
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• pp.19.1-19.11
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• 2018

MicroRNAs (miRNAs), small non-coding RNAs, have been implicated in various diseases and cellular functions as microregulators of gene expression. Although the history of miRNA investigation in autoimmune $Sj{\ddot{o}}gren^{\prime}s$ syndrome (SjS) is fairly short, a substantial amount of data has already been accumulated. These findings clearly indicate potential clinical implications of miRNAs, such as autoantigen expression and autoantibody production, viral miRNAs regulating the calcium signaling pathway, and aberrant immune cell regulation and cytokine production. Research endeavors in the field are currently underway to select disease-specific diagnostic and prognostic biomarkers by utilizing different types of tissues or biological specimens of SjS patients. Various techniques for miRNA analysis with different stringencies have been applied, with the most recent one being next-generation sequencing. This review compiles and highlights differentially-expressed miRNAs in various samples collected from SjS patients and their potential implications in the pathogenesis of SjS. To facilitate the development of miRNA-targeted personalized therapy in the future, we urge more follow-up studies that confirm these findings and elucidate the immunopathological roles of differentially-expressed miRNAs. Furthermore, improved diagnostic criteria for the disease itself will minimize sampling errors in patient recruitment, preventing the generation of inconsistent data.

• Restorative Dentistry and Endodontics
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• v.45 no.4
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• pp.48.1-48.11
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• 2020

Objectives: This systematic review aimed to identify mean oxygen saturation values (SpO₂) using pulse oximetry in permanent maxillary anterior teeth. Materials and Methods: The MEDLINE, Scientific Electronic Library Online, Cochrane Central Register of Controlled Trials, EMBASE, and Literatura Latino Americana em Ciências da Saúde electronic databases were searched. Combinations and variations of "oximetry" AND "dental pulp test" were used as search terms. Studies reporting means and standard deviations of SpO₂ values were included. Two reviewers independently extracted data following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Heterogeneity was assessed using the I² statistic, and all analyses were performed using R software. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool and the Newcastle-Ottawa scale. Results: Of the 251 studies identified, 19 met the eligibility criteria and were included (total sample, 4,541 teeth). In the meta-analysis, the mean SpO₂ values were 84.94% (95% confidence interval [CI], 84.85%-85.04%) for the central incisors, 89.29% (95% CI, 89.22%-89.35%) for the lateral incisors, and 89.20% (95% CI, 89.05%-89.34%) for the canines. The studies were predominantly low-quality due to the high risk of bias associated with the index test, unclear risk regarding patient selection, and concerns about outcome assessment. Conclusions: Although most studies were low-quality, the oxygen saturation levels in normal pulp could be established (minimum saturation, 77.52%). Despite the risk of bias of the included studies, the reference values reported herein are clinically relevant for assessments of changes in pulp status.

• The Journal of the Korean dental association
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• v.50 no.4
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• pp.189-195
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• 2012

Various imaging modalities have been used for dental implant assessment in the different stages of implant treatment. Basic imaging, such as panoramic and periapical radiographs, are generally useful and cost-effective but do not provide the cross-sectional visualization or interactive image analysis that can be obtained with more sophisticated imaging techniques, such as Cone-Beam Computed Tomography(CBCT) imaging. This article includes the applications of CBCT imaging and their diagnostic contribution to presurgical evaluation, treatment planning, and postoperative assessment of dental implants.

• Journal of the Korean Data and Information Science Society
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• v.5 no.2
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• pp.95-106
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• 1994

A proposed test statistic is obtained by multiplying constant weights by the Neumann smooth type statistic discussed by Eubank and Hart(1993) in order to observe the effect of weight. It has very good results of power studies. Another advantage of this test is that it simultaneously provides an important diagnostic tools that can be used in many cases to determine how the model should be adjusted.

• Journal of ILASS-Korea
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• v.5 no.4
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• pp.12-32
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• 2000

The recent trends in numerical simulation of various spray phenomena are reviewed in this article. Major subtopics are atomization/breakup, collision/coalescence, wall collision, interfacial transfer, droplet dispersion, two-phase injection and spray combustion. Each submodel has been under continuous refinement and validation against more extensive data base by advanced laser diagnostic techniques. Most uncertainty in current spray simulations come from these physical submodels, not from excessive computational constraints.

• Proceedings of the KIEE Conference
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• 1999.11d
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• pp.1048-1050
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• 1999

It is difficult to maintain cast resin transformer in the field. In this paper, we developed the diagnosis techniques to detect degrade of cast resin transformer using partial discharge, EMI and material analysis.

• Journal of Biomedical Engineering Research
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• v.9 no.1
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• pp.131-134
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• 1988

In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network.

• 축산식품과학과 산업
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• v.2 no.1
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• pp.40-46
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• 2013

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1994.05a
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• pp.50-56
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• 1994

Partial discharge on organic insulation surfaces are an important sauce of aging. Furthermore the modern PD measurement technigues are rapid developed as quality control and diagnostic tests to determine the fitness for use of HV equipment employing sol id electrical insulation. This paper deals with theory of conventional PD measurement and new tendency of technical development on PD measurements und evaluations. Finally the Measuring system used for diagnosing the surface aging on the organic insulation at High Voltage Laboratory of Technical University of Darmstadt in Germany is presented.

• Journal of Chest Surgery
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• v.14 no.4
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• pp.399-402
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• 1981

Because of recent advances in cardiac surgery and diagnostic techniques, left ventricular-right atrial communication has been reported with increasing frequency. Recently we experienced 2 cases of left ventricular-right atrial communication, which were corrected surgically. Preoperative diagnosis was incorrect In both cases as ventricular septal defect. The type of defect was supravalvular in case 1 and case 2. Both cases were successfully closed with the aid of extracorporeal circulation and discharged with good results.