• 한국IT서비스학회지
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• 제11권4호
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• pp.153-170
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• 2012

When companies or institutes manage data, in order to utilize it as useful resources for decision-making, it is essential to offer precise and reliable data. While most small and medium-sized enterprises and public institutes have been investing a great amount of money in management and maintenance of their data systems, the investment in data management has been inadequate. When public institutions establish their data systems, inspection has been constantly carried out on the data systems in order to improve safety and effectiveness. However, their capabilities in improving the quality of data have been insufficient. This study develops an automatic tool to diagnose the quality of data in a way to diagnose the data quality condition of the inspected institute quantitatively at the stage of design and closure by inspecting the data system and proves its practicality by applying the automatic tool to inspection. As a means to diagnose the quality, this study categorizes, in the aspect of quality characteristics, the items that may be improved through diagnosis at the stage of design, the early stage of establishing the data system and the measurement items by the quality index regarding measurable data values at the stage of establishment and operation. The study presents a way of quantitative measurement regarding the data structures and data values by concretizing the measurement items by quality index in a function of the automatic tool program. Also, the practicality of the tool is proved by applying the tool in the inspection field. As a result, the areas which the institute should improve are reported objectively through a complete enumeration survey on the diagnosed items and the indicators for quality improvement are presented quantitatively by presenting the quality condition quantitatively.

• 정보처리학회논문지A
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• 제16A권5호
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• pp.403-410
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• 2009

본 논문에서는 교수자에게 학습자의 지식 요소별 진단을 해 주는 것이 가능한 지능형 온라인 퀴즈를 저작할 수 있도록 해주는 교육용 소프트웨어에 대하여 소개한다. 이 도구는 베이지언 추론망을 활용하여 학습 요소들 간의 관계를 표현함으로써 학습자 모델을 설계하고 베이지언추론에 의해 학습자의 지식을 추론하는 진단 엔진을 자동적 생성한다. 또한 이 도구는 온라인 퀴즈 페이지를 생성하며 퀴즈 풀이 후에 학습자 보고서를 제시하며 학습자 개인별로 부족한 학습 요소를 보충하기 위한 콘텐츠를 제공하는 기능을 갖추고 있다. 저작도구 자동생성 기법에 따라 개발된 이 지능형 온라인 퀴즈 저작도구는 학습자 개인의 부족한 학습 요소를 파악함으로써 그 진단 결과에 따른 학습전략 수립과 다음 학습 내용 선택 그리고 부족한 지식 요소를 보강하기 위한 보충학습을 수행하는데 도움을 주는 것으로 나타났다.

• 정보처리학회논문지B
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• 제13B권2호
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• pp.97-104
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• 2006

의사 표현 능력이 떨어지는 소아들은 질병 발생시 이를 효과적으로 자신의 불편함을 표현할 방법이 없다. 따라서 임상의들은 소아 환자의 부모들로부터 문진(inquiring)을 통해 질병 진단을 하고 있는 것이 현 실정이며 이는 잘못된 진단 결과를 초래 할 수 있는 문제점을 가지고 있다. 이를 위해 본 연구에서는 인체 오장 육부의 생체 신호가 안면과 음성에 반영되어 나타난다는 한방 원리를 이용하여 소아 망진, 소아 청진 기기를 개발한다. 그 결과 진단시 임상의들의 직관을 시각화, 객관화, 정량화하여 소아 질병 진단의 정확성을 기하고자 한다. 본 논문은 전체 개발 시스템 중 그 첫 번째 작업 수행 결과로서 소아 망진의 경우 색상 보정, YCbCr 적용과 살색 영역 선정 그리고 오관 및 명당 추출 방법 등을 개발한다. 또한 소아 청진의 경우 피치, 강도, 포먼트 분석을 통해 영아 산통 질병의 울음소리 특성을 수치화하였으며 이를 통해 임상의들의 직관을 객관화한다. 끝으로 실험에 의해 제안한 방법의 유용성을 입증한다.

• 대한한방부인과학회지
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• 제30권4호
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• pp.175-202
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• 2017

Objectives: This study was conducted towards developing a screening tool for syndrome differentiation in the diagnosis of menopause in menopausal and perimenopausal women. Methods: We conducted a literature review of studies on menopausal diagnosis based on syndrome differentiation, and examined well-founded differentiated syndromes and their respective clinical symptoms. Based on the findings, we created a questionnaire through consultations with Oriental medicine experts in physiology, pathology, and diagnostics. Finally, the research team conducted an expert Delphi study on differentiated syndromes and the associated clinical symptoms. Results: Seven differentiated syndromes were selected, including Liver Depression (肝鬱), Kidney Yin Deficiency (腎陰虛), Kidney Yang Deficiency (腎陽虛), Liver and Kidney Yin Deficiency (肝腎陰虛), Kidney Yin and Yang Deficiency (腎陰陽兩虛), Heart-Kidney Noninteraction (心腎不交), and Dual Deficiency of Heart and Spleen (心脾兩虛); 4 disease locations, including liver (肝), heart (心), spleen (脾), and kidney (腎); and 3 disease natures, including Yin Deficiency (陰虛), Qi Stagnation (氣滯), and Blood Deficiency (血虛). In addition, we added 3 supplemental disease natures, including Yang Deficiency (陽虛), Qi Deficiency (氣虛), and Heat (火熱), in consideration of syndrome differentiation categories that may possibly be added in a follow-up clinical questionnaire. Conclusions: This resulted in a total of 7 differentiated syndromes, 4 disease locations, and 6 disease natures. We translated the clinical symptoms of these 17 categories into Korean Hangeul. After consulting with 5 Oriental medicine experts and a psychology expert, we produced a questionnaire for use in diagnosing menopause based on syndrome differentiation. The calculation of scores for the syndrome differentiation screening tool will be confirmed through clinical research based on the results of a review of existing literature.

• Journal of Preventive Medicine and Public Health
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• 제19권2호
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• pp.233-243
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• 1986

Our study was designed to identify the difference in the mental health status among hospitalized patients due to occupational diseases and accidents and pre-employment physical examinees, and to identify the relationship between mental health status and socio-demographic variables, and to provide information useful to non-psychiatric clinicians in caring of such patients. Samples were comprised of 189 pneumoconiotic patients, 132 industrial accident-induced patients and 122 pre-employment physical examinees who were interviewed with 90-item symptom cheklist (SCL-90). The following results were obtained: 1) Mean scores of symptom dimension on socio-demographic subgroup showed higher tendencies in older aged, male, lower educated, miner, married, mining residence, and pneumoconiotic patients. 2) Mean scores of total samples on all symptom dimensions were as follows in the order of their magnitudes; Depression, Somatization, Obsessive-compulsive, Anxiety, Psychoticism, Interpersonal sensitivity, Phobic-anxiety, Hostility, and Paranoid ideation. 3) The highest mean scores on each socio-demographic subgroup were as follows; Depression in younger aged and Somatization in older aged; Depression in male Somatization in female; Somatization in lower educated and depression in higher educated; Somatization in miners and depression in non-miners; Somatization in married and Depression in unmarried; Depression in all kind of residences; Somatization in patients and Depression in pre-employment physical examinees(normal). 4) In consequence of stepwise multiple regression, the important socio-demographic variables were age, occupation, diagnostic classification, and residence. Age was the most imprtant variable in Somatization, Depression, Obsessive-compulsive, Anxiety, Phobic anxiety, Paranoid ideation, and Psychoticism. Occupation was the most important one in Interpersonal sensitivity and Hostility and also had significant realtionships with all symptom dimensions.

• Journal of Genetic Medicine
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• 제11권2호
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• pp.63-68
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• 2014

Purpose: The mutation of the SLC26A4 gene is the second most common cause of congenital hearing loss after GJB2 mutations. It has been identified as a major cause of autosomal recessive nonsyndromic hearing loss associated with enlarged vestibular aqueduct and Pendred syndrome. Although most studies of SLC26A4 mutations have dealt with hearing-impaired patients, there are a few reports on the frequency of these mutations in the general population. The purpose of this study was to evaluate the prevalence of SLC26A4 mutations that cause inherited deafness in the general Korean population. Materials and Methods: We obtained blood samples from 144 Korean individuals with normal hearing. The samples were subjected to polymerase chain reaction to amplify the entire coding region of the SLC26A4 gene, followed by direct DNA sequencing. Results: Sequencing analysis of this gene identified 5 different variants (c.147C>G, c.225G>C, c.1723A>G, c.2168A>G, and c.2283A>G). The pathogenic mutation c.2168A>G (p.H723R) was identified in 1.39% (2/144) of the subjects with normal hearing. Conclusion: These data provide information about carrier frequency for SLC26A4 mutation-associated hearing loss and have important implications for genetic diagnostic testing for inherited deafness in the Korean population.

• 대한의용생체공학회:의공학회지
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• 제27권4호
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• pp.154-163
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• 2006

A 64-channel magnetocardiogram (MCG) system using low-noise superconducting quantum interference device (SQUID) planar gradiometers was developed for the measurements of cardiac magnetic fields generated by the heart electric activity. Owing to high flux-to-voltage transfers of double relaxation oscillation SQUID (DROS) sensors, the flux-locked loop electronics for SQUID operation could be made simpler than that of conventional DC SQUIDs, and the SQUID control was done automatically through a fiber-optic cable. The pickup coils are first-order planar gradiometers with a baseline of 4 em. The insert has 64 planar gradiometers as the sensing channels and were arranged to measure MCG field components tangential to the chest surface. When the 64-channel insert was in operation everyday, the average boil-off rate of the dewar was 3.6 Lid. The noise spectrum of the SQUID planar gradiometer system was about 5 fT$_{rms}$/$\checkmark$Hz at 100 Hz, operated inside a moderately shielded room. The MCG measurements were done at a sampling rate of 500 Hz or 1 kHz, and realtime display of MCG traces and heart rate were displayed. After the acquisition, magnetic field mapping and current mapping could be done. From the magnetic and current information, parameters for the diagnosis of myocardial ischemia were evaluated to be compared with other diagnostic methods.

• 대한의용생체공학회:의공학회지
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• 제24권4호
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• pp.275-280
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• 2003

일반적으로 MR Angiography(MRI)는 사전 포화방법(presaturation)을 이용하여 동맥과 정맥의 분리된 영상을 획득한다. 하지만 이러한 일반적인 사전포화방법으로 동맥과 정맥영상을 획득하기 위해서는 두 번의 영상획득이 필요하다. 따라서 본 연구에서는 동맥과 정맥의 구분된 영상을 한번의 영상획득으로 얻을 수 있는 SAAV 기법을 0.3T MRI system에 적용하고, 획득한 동맥과 정맥의 두 MRA 영상을 Colot-Mapping으로 동$.$정맥을 한 영상에 구분하여 나타냄으로써 0.3T MRI system에서 MRI의 임상적 적용 및 활용 가능성을 높이고자 하였다. 마산 삼성병원의 0.3T MRI system (Magfinder, AILab. Korea)어서 SAAV sequence를 이용하여 정상적인 피험자로부터 목 부위의 동맥과 정맥 혈관영상 (volume : 256${\times}$256${\times}$64)을 동시에 얻었다. 그리고. 이들의 각 2D 영상들에서 위치정보를 획득한 후 MIP 기법과 Color Mapping으로 조합하여 3D Artery-Vein Color Mapping(AVCM) MRA 영상으로 재구성하였다.

• 한국정보과학회논문지:소프트웨어및응용
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• 제27권8호
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• pp.815-826
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• 2000

본 연구는 사람의 뇌에 대한 자기공명영상에서 백질과 회백질을 분리하고 각각의 체적을 산출하기 위한 것이다. 일반적으로 치매나 다운증후군 같은 정신질환의 경우 백질 또는 회백질의 위축으로 인해 체적이 감소하게 되므로, 사람의 뇌에 대하여 백질과 회백질의 체적 산출을 통한 크기의 변화를 추적함으로서 여러 정신질환의 진단 및 조기 발견에 유용하게 이용될 수 있다. 그러나 일정한 두께의 단면을 촬영하여 단일의 명암 값으로 표현하는 자기공명영상기기의 특성상 번짐 현상을 보이는 자기공명영상으로부터 원래의 두께 안에 존재하는 각 성분의 부분체적을 산출할 수 없음으로 인해 백질과 회백질의 체적산출이 현재까지 불가능하였다. 따라서 본 논문에서는 번짐(blurred)을 보이는 자기공명영상에서 번진 명암 값을 해석하는 새로운 알고리즘에 의해 백질과 회백질의 부분체적을 산출하고, 이를 근거로 자기공명영상에서 백질과 회백질을 분리하기 위한 판별값을 결정하였으며, 결정된 판별값에 의해 분리된 영상에서 백질과 회백질의 체적을 산출하였다. 또한 제안된 알고리즘의 검증을 위해 인위적으로 생성된 모델에 알고리즘을 적용하여 산출된 결과를 원래의 모델과 비교하여 보았다.

• Journal of Korean Neurosurgical Society
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• 제29권3호
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• pp.345-352
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• 2000

Objective : The purpose of this study was to compare computed tomographic angiography(CTA) with conventional cerebral angiography(CCA) and to assess usefulness of CTA in detection and anatomic definition of intracranial aneurysms of the circle of Willis in subarachnoid hemorrhage. Patients and Methods : Fifty consecutive patients with known or suspected intracranial saccular aneurysms underwent CTA with preoperative CCA from 1997 to 1999. Using surface shaded display post-processing technique, CTA was interpreted for the presence, location of aneurysms and anatomic features. The image obtained with CTA was then compared with CCA image. Results : In 47 patients, CCA revealed 57 cerebral aneurysms and CTA revealed 54 aneurysms. Two of the 57 cerebral aneurysms were located outside of the imaging volume of CTA and one case was misdiagnosed. The sensitivity of CTA was 94.7% and the specificity was 100%. The results obtained with CTA were, compared with the results obtained with CCA, equal in determining dome shape, direction and lobularity. However, CTA provided a 3-dimensional representation of aneurysmal lesion very useful for surgical planning. Moreover, CTA was useful for rapid and relatively noninvasive detection of aneurysms in the circle of Willis. Conclusion : CTA can be a diagnostic tool for the patients with acute subarachnoid hemorrhage due to a ruptured aneurysm of the circle of Willis and provides adequate anatomic detail for surgical planning, especially to complex cerebral aneurysms. However, we think CCA is necessary because of CTA limitations including its difficulty in detecting unusually located aneurysms(including those in cavernous sinus or distal artery) and combined vascular lesion (including arteriovenous malformation) and acquiring dynamic flow information.