• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7409-7414
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• 2013

Background: Delay in diagnosis of breast cancer is associated with a poorer survival and a pivotal contribution to this delayed diagnosis comes from patient delay in presenting at a clinic. Reasons involved must be evaluated in order to decrease this reducible delay. Objectives: i) To evaluate the reasons for patient delay in diagnosis of breast cancer; ii) to investigate any association with other variables. Materials and Methods: A 6 month cross sectional study (from July 2012 to Dec 2012), was carried out in Surgical and Oncology Units of Civil Hospital, Karachi. A total of 100 females diagnosed with breast cancer of any histological type were interviewed after informed consent and relevant data were collected. Due ethical clearance was obtained. Results: Mean age was $47.5{\pm}12.1$ years with a range from 25-77 years. Mean duration of delay was $5.13{\pm}4.8$ months, from shortest 1 month to longest 36 months. Duration of delay was observed to be no delay (<1 month) in 28%, short delay (1-3 months) in 30% and long delay (>3 months) in 42% of patients. Considering the symptoms as "harmless" (39%) was the most frequent reason of delay followed by "temporary" (20%) and the "use of traditional methods" (12%). Most common reason for later approaches was an increase in the size of the lump (41%). Statistically significant association (p-value <0.05) of longer patient delay was obtained with being single, being illiterate, painless breast lump as the first symptom, negative family history of breast cancer and vague attribution of the symptoms. Conclusions: Significant delay in approach to health care facility was observed in our study due to variable reasons given by women. Sufficient awareness regarding breast cancer, its symptoms and favorable effects of a timely diagnosis on prognosis must be imparted to our general population.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.1109-1114
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• 1992

Modern chemical processes are becoming more complicated. The sophisticated chemical processes have needed the fault diagnosis pxpert systems that can detect and diagnose the fault diagnosis expert systems that can detect and diagnose the faults of some processes and give and advice to the operator in the event of process faults. We present the Time-Delay Neural Network(TDNN) approach for on-line fautl diagnosis. The on-line fault diagnosis system finds the exact origin of the fault of which the symptom is propagated continuously with time. The proposed method has been applied to a pilot distillation column to show the merits and applicability of the TDNN.

• 유공압시스템학회논문집
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• 제3권1호
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• pp.7-14
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• 2006

In this paper, an in-process diagnosis method for performance of position control servo system was studied, which was based upon null bias, slew-rate ratio and delay time measurement. Slew-rate ratio and delay time were analyzed by theoretical analysis, computer simulation and experiment. As a result of these analysis, when spool of servovalve was weared, slew-rate ratio was decreased and delay time was increased.

• Asian Pacific Journal of Cancer Prevention
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• 제17권11호
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• pp.5037-5040
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• 2016

Objectives: To determine the frequency of delayed diagnosis of oral squamous cell carcinoma in our setup; highlighting factors responsible for any delay and their possible relevance to demographic and diagnostic features. Methods: This cross sectional study of six months duration was conducted in the Oral and Maxillofacial Surgery Department of the Armed Forces Institute of Dentistry, Rawalpindi, Pakistan. A total of 246 patients, both male and female, having a biopsy proven definitive diagnosis of OSCC were included using a consecutive sampling technique. Delay in diagnosis was assessed from the stated period of time from when the patient first noticed symptoms of disease until a definitive diagnosis was made. We concluded delayed diagnosis if this was more than 40 days. Results: The ages of patients ranged from 27 to 60 years with a mean of $46.7{\pm}10.2$ years and a marked male predominance (3.7:1). Delayed diagnosis was observed in 91.5% of cases. However, statistically no significant differences were found with age, gender, marital, education status, household income and time of biopsy. Conclusion: Our primary finding of delayed diagnosis with no prior contact with any health care professional clearly reflects a need of taking urgent measures to avoid serious impacts on morbidity and mortality associated with OSCC.

• 한국방사선학회논문지
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• 제13권2호
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• pp.305-311
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• 2019

본 연구에서는 이중 시간 PET/CT 검사에서 지연검사 시간이 다른 두 그룹의 40명의 췌장암 환자에 대한 SUV 데이터의 통계 분석을 통해 최적의 지연검사 시간을 제시하였다. 췌장암의 유무를 확인해야 될 이중 시간 PET/CT 검사에서 새로운 수학적 예측 모델을 만들어 정확도 높은 최적의 지연검사 시간을 제시하였다. 시간에 따른 포도당 대사를 적용한 방사능 붕괴식을 예측 모델로 제시하였다. 지연검사 시간이 다른 두 그룹의 데이터를 가지고 시뮬레이션한 결과 PET/CT에서 췌장암 판별을 위한 최적의 지연검사 시간이 131.5분으로 제시하였다. 제안된 지연검사 시간은 췌장암 결정에 적용될 수 있는 통계적 유의 수준을 보였다(p<0.05). 제안된 지연 검사 시간 131.5분을 결정하여 검사를 진행할 때, 췌장암 조기 판별에 도움을 줄 수 있을 것으로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.759-765
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• 2016

Background: Breast cancer is the most frequent cancer of women in Pakistan with the majority presenting with stage III or IV lesionsat initial diagnosis. Patient and health system related factors are well known determinants of delay in presentation and diagnosis. Additionally, breast cancer being a heterogeneous disease, the various molecular subtypes featuring different aggressiveness also need to be considered. The present study evaluated the association of stage at initial diagnosis of breast cancer with these two factors in local women at a tertiary level health care facility in Lahore, Pakistan. Materials and Methods: Patient and tumor features were recorded separately during diagnostic workup in Breast Clinics at INMOL and at Services Hospital, Lahore. Data were entered in MS Excel and analyzed by descriptive statistics and Chi-Square test. Results: Among the 261 patients, 64% were staged as late breast cancer (LBC), the mean age was 46.8 with standard deviation of 13 years. Some 92% had invasive ductal carcinoma (IDC), 61% had luminal types (LT) of non-aggressive tumor while 39% had the non-luminal types (NLT) of of HER2-enriched or basal aggressive tumors. While 70% of patients presented within one year of symptomatic disease (early report group "ERG"), 30% reported after a mean delay of 4 years with a standard deviation of 3.75 years. The stage distribution among ERG patients was not statistically different from those reporting late (P=0.123). Statistically larger proportion of patients with NLT presented as LBC as compared to the LT (P =0.034). Among the ERG, statistically different stage distribution of disease was observed for the NLT versus LT (P=0.047). Among those presenting late, this difference was insignificant (P=0.416). Conclusions: Breast cancer is a distinct disease in Pakistan with a high frequency of aggressive molecular types affecting younger women, with the majority presenting as LBC. Association of NLT with higher stage at diagnosis is statistically significant whereas time delay in diagnosis is not. Further research is required to define the risk profile and features in local patients. The burden of LBC can be reduced by promoting breast health awareness and by establishing easily accessible dedicated breast care set ups in the hospitals.

• International Journal of Control, Automation, and Systems
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• 제1권3호
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• pp.308-314
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• 2003

This paper presents a serial communication based fault diagnosis scheme for a brushless DC (BLDC) motor using parameter estimation and Bayes classifier. The presented scheme consists of a smart network board, and a fault detection and isolation (FDI) master. The smart network board is installed near the BLDC motor drive system to acquire motor data and transmit motor data to the FDI-master via serial communication channel. The FDI-master estimates BLDC motor resistance to detect symptom of faults, and assign symptom to fault type using Bayes classifier. In this scheme, since communication time delay has a serious effect on performance, periodic and fixed communication protocol is designed. Hence, the delay time is priory known. By experiment result, presented scheme was verified.

• 대한전자공학회논문지
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• 제26권8호
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• pp.1217-1226
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• 1989

This paper describes a design of hardware system for real time automatic diagnosis of ECG arrhythmia based on pipeline processor consisting of three microcomputer. ECG data is acquisited by 12 bit A/D converter with hardware QRS triggered detector. Four diagnostic parameters-heart rate, morpholigy, axis, and ST segment-are used for the classification and the diagnosis of arrhythmia. The functions of the main CPU were distributed and processed with three microcomputers. Therefore the effective data process and the real time process using microcomputer can be obtained. The interconnection structure consisting of two common memory unit is designed to decrease the delay time caused by data transfer between processors and be which the delay time can be taken 1% of one clock period.

• Korean Journal of Radiology
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• 제24권10호
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• pp.941-943
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• 2023

• 대한골관절종양학회지
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• 제9권1호
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• pp.18-23
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• 2003

목적: 골 육종, 연골 육종은 흔한 질환이 아니므로, 일차 진료 현장에서 명확한 진단이 신속히 이루어지지 않고, 진단의 지연이나 오진으로 인해 문제를 야기할 수 있다. 따라서, 상기 질환에 대한 초기 증상과 임상적 특징을 조사하여 이를 확인하고, 조기 진단에 도움을 주고자한다. 대상 및 방법: 본원에서 진단된 골 육종이나 연골 육종 환자로, 기록 검토와 설문지 조사가 가능한 139명을 대상으로 하였다. 골 육종 환자가 108명, 연골 육종이 31명이었고, 남자가 86명, 여자가 53명이었으며, 평균 연령은 골 육종이 20.2세, 연골 육종이 42.4세이었다. 결과: 병원을 방문하게 된 초기 증상은 두 질병 군 모두에서 동통이 가장 많았는데, 골 육종은 101명(93.5%), 연골 육종은 19명(61.3%)이었다. 이들 중 골 육종의 49명(48.5%), 연골 육종의 1명(5.3%)에서 통증이 외상과 관련되어 시작되었으며, 야간 동통이 골 육종의 77명(76.2%), 연골 육종의 11명(57.8%)에서 있었다. 처음 방문한 진료 기관에서 악성 골 종양으로 진단된 경우는 골 육종에서는 66명(61.1%), 연골 육종에서 20명(64.5%)이었고, 오진된 경우는 골 육종에서는 골절로 본 경우가 18명(16.7%)으로 가장 많았으며, 연골 육종에서는 골 감염으로 본 경우가 6명(19.4%)으로 가장 많았다. 초진 시에 방사선 촬영을 시행한 경우 골 육종과 연골 육종 모두에서 진단율이 유의하게 높았고(p=0.009, p=0.014), 성인 군에서의 진단율이 높았다(p=0.037). 연골 육종에서 골 육종보다 환자와 의사에 의한 지연이 모두 길었다. 진단의 의사 지연을 길게 하는 요소로는 초진 시에 단순 방사선 사진을 촬영하지 않는 것과 골반 등 축성골에 종양이 위치하는 것이었고, 외상과 미성년 환자는 진단의 환자 지연을 단축시킬 수 있는 요소로 파악되었다. 결론: 악성 골 종양의 조기 진단을 위해서는 외상이나 야간 동통 등의 병력 청취를 소홀히 하지 않아야 할 것이며, 초진시의 단순 방사선 촬영과 주기적인 경과 관찰 및 방사선 사진의 비교 등으로 조기 진단의 정확성에 힘써야 할 것이다.