• Title/Summary/Keyword: Developmental regulation

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유아의 인지적 실행기능 및 정서적 실행기능과 자기 조절간의 관계 : 만 3-5세 유아의 발달 차이를 중심으로 (Development of Children's Cool and Hot Executive Function and its Relationship to Children's Self-Regulation)

  • 최은아;송하나
    • 아동학회지
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    • 제34권5호
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    • pp.99-114
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    • 2013
  • This study examined the relationships between children's cool executive function(cool EF), hot executive function(hot EF) and self-regulation according to the developmental changes. Children aged 3-5 years (N = 104) participated in this study. The participants completed cool and hot EF tasks and teachers reported on the children's cognitive regulation, emotional regulation, and behavioral regulation by means of questionnaires. The results indicated that cool EF and hot EF had different developmental patterns according to different age groups. High levels of cool/hot EF predicted better abilities in terms of cognitive, emotional, and behavioral regulation respectively. The relationship between coo/hot EF and cognitive/behavioral regulation were moderated by age, except in the case of emotional regulation. This paper also offers a detailed discussion of results and recommendations for future studies.

PAF Regulate Blastocyst Development to Hatching Stage through PKC Activity in the Mouse

  • Cheon Yong-Pil
    • Reproductive and Developmental Biology
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    • 제30권2호
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    • pp.75-79
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    • 2006
  • The developmental regulation of the preimplantation mammalian embryos is a fundamental step for preparing the implantation and it may be regulated by several autocrine and paracrine factors including platelet-activating factor. PAF improved the embryonic survival and implantation but its role during blastocyst development is still largely unknown. In this study, the effects and the possible pathway of PAF on developmental regulation of blastocyst to hatching stage were investigated. Developmental pattern in hatching embryo was a concentration-response curve showing maximal activity at 1 nM PAF, with decreasing activity at higher concentrations. $50{\mu}M$ 1-(5-isoquinolimnesulfonyl)-2-methylpiperazinme dihydrochloride (H-7), a PKC inhibitor, inhibited the progression of blastocyst to hatching embryo. In addition H-7 blocked the PAF effects on the blastocyst development. Besides tetradecanoylphorbol acetate (TPA), a PKC activator stimulated development of blastocyst to the hatching stage. These finding revealed that PAF support the blastocyst development to the hatching embryo. Also it is suggested that PAF action pathways in hatching supporting include the PKC signaling pathway.

유아 정서지능 발달에 관한 연구 (Developmental trends of children's emotional intelligence)

  • 김경희;김경희
    • 아동학회지
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    • 제21권4호
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    • pp.21-34
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    • 2000
  • This investigation of developmental trends in children's emotional intelligence used the Emotional Intelligence Rating Scale for Preschool Children(Kim, 1998) to study 973 children. Significant age differences were found in 5 factors: 'utilization of emotion', 'regulation of emotion', 'handling of relationship between child and teacher' and 'handling of relationship with peers'. Children's emotional intelligence scores increased with age in 3 factors: 'utilization of emotion', 'empathy', and 'regulation of emotion'. Sex differences were found in 5 factors: 'utilization of emotion', 'empathy', 'appraisal and expression of self emotion', 'regulation of emotion', and 'handling of relationship between child and teacher'. In all factors, the scores of girls were higher than those the scores of boys.

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Developmental Regulation of Caenorhabditis elegans DNA Topoisomerase I Expression

  • Jang, Yeon-Joo;Park, Hyung-Ki;Lee, Jun-Ho;Koo, Hyeon-Sook
    • BMB Reports
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    • 제31권3호
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    • pp.249-253
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    • 1998
  • The developmental regulation of Caenorhabditis elegans DNA topoisomerase I expression was examined using synchronized Caenorhabditis elegans cultures. Variations of the relative mRNA and protein levels of the enzyme during their development were measured by Northern and Western analyses, respectively. The mRNA level was the highest at the embryonic stage, decreasing rapidly to the one tenth level at the L1 stage, and then increasing by a few fold at the L4 and young adult stages. The protein level was the highest at the L1 stage, with gradual decreasing at the following stages until it showed a slight increase at the young adult stage. Based on our results of the expressional regulation, the possible roles of DNA topoisomerase I in the development of C. elegans are discussed.

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노랑초파리의 $\alpha$-Glycerol-3-phosphate Dehydrogenase (GPDH)의 발현과 조절 (Regulation and Expression of Glycerol-3-phosphate Dehydrogerlase (GPDH) in Drosophila melanogaster)

  • 김세재;이정주남궁용김경진
    • 한국동물학회지
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    • 제34권1호
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    • pp.123-130
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    • 1991
  • Several parameters of u -glycerol-3-pholphate dehydrogenase (GPDH) such as activity, content and translatable mRNA levels were measured to elucidate mechanism underlving developmental and tissue specific regulation of 6PDH activity in Drosophila melonogastrr. In adult segments, most of total GPDH activity (62%1 Iwas detected in thorax where GPDH-1 resided, while 32% of total GPDH aUiviD was only detected in abdomen where GPDH-3 resided. The relative synthesis of GPDH was, however, similar in both tissues, although 58% of total GPDH was synthesized in abdomen. These results strongly suggest that the turnover rate of the abdominal enzyme (GPDH-3) was much more rapid than that of thoracic enzymes (GPDH-1). In nitro translation and immunoblotting experiments also indicate that GPDH-3 was arised by posttranslational modification from a single polypeptide (GPDH-1).

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