• 제목/요약/키워드: Developmental Model

검색결과 648건 처리시간 0.022초

국토환경성평가 지표를 이용한 환경용량 산정모델 개발 (A Development of Environmental Capacity Estimation Model Using the National Environmental Assessment Indicators)

  • 이종수;이우균;전성우
    • 환경영향평가
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    • 제15권6호
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    • pp.385-394
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    • 2006
  • Land resources should be managed not only for human utilizations but also for environmental preservation. Based on that, environmental capacity should be estimated in both environmental and developmental ways. This study was performed for developing an estimation model for relative environmental capacity, considering both Development Tolerance Index(DTI), which shows environmental and ecological conservation value and is based on national environmental assessment indicators of the Korea Ministry of Environment, and Development Attractiveness Index(DAI), which shows topographical characteristics and geographical accessibility. The relative environmental capacity in this study can be helpful to coping with the conflict in planning and managing the use of land resources. The relative environmental capacity in this study, however, did not include either environmental or ecological sensitivity of land resources. This limitation should be solved through further research.

Fertilization and the oocyte-to-embryo transition in C. elegans

  • Marcello, Matthew R.;Singson, Andrew
    • BMB Reports
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    • 제43권6호
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    • pp.389-399
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    • 2010
  • Fertilization is a complex process comprised of numerous steps. During fertilization, two highly specialized and differentiated cells (sperm and egg) fuse and subsequently trigger the development of an embryo from a quiescent, arrested oocyte. Molecular interactions between the sperm and egg are necessary for regulating the developmental potential of an oocyte, and precise coordination and regulation of gene expression and protein function are critical for proper embryonic development. The nematode Caenorhabditis elegans has emerged as a valuable model system for identifying genes involved in fertilization and the oocyte-to-embryo transition as well as for understanding the molecular mechanisms that govern these processes. In this review, we will address current knowledge of the molecular underpinnings of gamete interactions during fertilization and the oocyte-to-embryo transition in C. elegans. We will also compare our knowledge of these processes in C. elegans to what is known about similar processes in mammalian, specifically mouse, model systems.

Novel Disease Model of Chronic Neutrophilic Leukemia

  • Seo, Byoung-Boo;Min, Sung-Hun;Lee, Eun-Ji;Ryoo, Zae-Young;Park, Hum-Dai
    • Reproductive and Developmental Biology
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    • 제35권4호
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    • pp.421-425
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    • 2011
  • The experimental manipulation of protooncogenes and their gene products is a valuable research tool for the study of human neoplasia. In this study, the recently identified human cervical cancer protooncogene (HccR-2) was expressed in transgenic mice under the control of the tetracycline regulatory system. The phenotype observed was similar in many respects to human chronic neutrophilic leukemia (CNL). Thus, the HccR-2 transgenic mouse model is important not only for investigating the biological properties of the HccR-2 protooncogene in vivo, but also for analyzing the mechanisms involved in the progression of CNL.

소셜 미디어 서비스 산업 후발기업의 Catch-up 전략 사례분석 (A Case Analysis on the Catch-up Strategy of Late-Comer Firms in the Social-Media Service Industry)

  • 함연주;조형래
    • 한국IT서비스학회지
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    • 제11권4호
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    • pp.309-333
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    • 2012
  • Recently, emergence of smart-phones and Social Networking Service(SNS) would offer the market environment changes and the opportunities for new business. For the case analysis comprehensive survey were implemented. And those data were analyzed along the research framework. The late-comer firms offered differential services, maintained creative and opened corporate culture, shoed learning capabilities which means absorption and organization of external knowledge, innovative efforts to control the insurgents than early-mover firms. When we analyze these phenomena along the developmental stages of late-comer, we can perceive that the stage of late-comers firms were moving from the "tracing the path" stage to "jumping the path" stage which means the creating capabilities were more or less enhanced and the firms become more stable in terms of business operation. In business model, early-mover firms showed clear definition for each business element, especially the revenue structure, while late-mover firms seemed unstable or unclear revenue structure.

Factors influencing positive subjective health awareness in multicultural adolescents in South Korea: Data from the multicultural adolescents panel study

  • Choi, Sun Yeob
    • Child Health Nursing Research
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    • 제27권4호
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    • pp.328-338
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    • 2021
  • Purpose: This study aimed to identify the factors influencing positive subjective health awareness of middle school-age multicultural adolescents in Korea. Methods: This study used data from the fourth to sixth waves of the Multicultural Adolescents Panel Study conducted by the National Youth Policy Institute. In this study, a panel logit model analysis was performed using the Eviews 8.0 program (p<.050). Results: Socioeconomic status (r=.02, t=2.13, p=.033), body satisfaction (r=.71, t=1.97, p=.048), and depression (r=-.74, t=2.35, p=.018) influenced positive subjective health awareness in multicultural adolescents. When multicultural characteristics were entered into a statistical model with environmental and personal characteristics, multicultural characteristics did not have a significant influence on positive subjective health awareness. Conclusion: Environmental, personal, and multicultural characteristics were related to positive subjective health awareness in multicultural adolescents; thus, an integrated approach considering those variables is recommended. Nursing interventions and educational programs are needed to improve the psychological status of multicultural adolescents and reduce prejudice about them. In addition, nurses need to be sensitive to multicultural characteristics and the developmental characteristics of multicultural adolescents.

Numerical simulation of air layer morphology on flat bottom plate with air cavity and evaluation of the drag reduction effect

  • Hao, W.U.;Yongpeng, O.U.
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제11권1호
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    • pp.510-520
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    • 2019
  • To investigate the morphology characteristics of air layer in the air cavity, a numerical method with the combination of RANS equations and VOF two-phase-flow model is proposed for a plate with air cavity. Based on the model above, the dynamic and developmental process of air layer in the air cavity is studied. Numerical results indicate that the air layer in the plate's air cavity exhibits the dynamic state of morphology and the wavelength of air layer becomes larger with the increasing speed. The morphology of air layer agrees with the Froude similarity law and the formation of the air layer is not affected by the parameters of the cavity, however, the wave pattern of the air layer is influenced by the parameters of the cavity. The stable air layer under the air cavity is important for the resistance reduction for the air layer drag reduction.

What Explains Smartwatch Adoption? A Compatrative Study of South Korea and Indonesia

  • Sekardhani, Mufida;Song, Sujin
    • Asia Marketing Journal
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    • 제24권2호
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    • pp.78-95
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    • 2022
  • Identifying factors that influence consumers' intentions to adopt a smartwatch has become a major research interest in marketing literature, yet little is known about it in dissimilar cultural settings. The current research employs a comparative study of South Korea and Indonesia, which differ in location and cultural heritage, smartwatch penetration rate, geographic size, level of income, and developmental stage as a country. An extended model of TAM is proposed, and PLS-SEM is employed to test the model on data collected from 262 respondents. The findings indicate that complementary goods and healthtology have positive influences on perceived usefulness and visibility has a positive influence on social image; these, together with perceived price value, lead to the behavioral intention to adopt a smartwatch in both countries. Perceived cost was only significant for Indonesia. Theoretical contributions and practical implications are further discussed.

Kidney Organoid Derived from Human Pluripotent and Adult Stem Cells for Disease Modeling

  • Hyun Mi Kang
    • 한국발생생물학회지:발생과생식
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    • 제27권2호
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    • pp.57-65
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    • 2023
  • Kidney disease affects a significant portion of the global population, yet effective therapies are lacking despite advancements in identifying genetic causes. This limitation can be attributed to the absence of adequate in vitro models that accurately mimic human kidney disease, hindering targeted therapeutic development. However, the emergence of human induced pluripotent stem cells (PSCs) and the development of organoids using them have opened up a way to model kidney development and disease in humans, as well as validate the effects of new drugs. To fully leverage their capabilities in these fields, it is crucial for kidney organoids to closely resemble the structure and functionality of adult human kidneys. In this review, we aim to discuss the potential of using human PSCs or adult kidney stem cell-derived kidney organoids to model genetic kidney disease and renal cancer.

Korean EFL Learners' Sensitivity to Stylistic Differences in Their Letter Writing

  • Lee, Haemoon;Park, Heesoo
    • 영어영문학
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    • 제56권6호
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    • pp.1163-1190
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    • 2010
  • Korean EFL learners' stylistic sensitivity was examined through the two types of letter writing, professional and personal. The base of comparison with the English native speakers' stylistic sensitivity was the linguistic style markers that were statistically found by Biber's (1988) multi-dimensional model of variation of English language. The main finding was that Korean university students were sensitive to stylistic difference in the correct direction, though their linguistic repertoire was limited to the easy and simple linguistic features. Also, the learners were skewed in the involved style in both types of the letters unlike the native speakers and it was interpreted as due to the general developmental direction from informal to formal linguistic style. Learners were also skewed in the explicit style in both types of letters unlike the native speakers and it was interpreted as due to the learners' heavy reliance on one particular linguistic feature. As a whole, the learners' stylistic sensitivity heavily relied on the small number of linguistic features that they have already acquired, which happen to be simple and basic linguistic features.

코칭기반 인성교육 프로그램이 초등학생의 인성향상에 미치는 효과 (The Effects of Coaching-Based Personality Education Program on the Improvement of Personality in Elementary School Students)

  • 최인숙;채명신
    • 한국융합학회논문지
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    • 제9권9호
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    • pp.229-243
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    • 2018
  • 본 연구의 목적은 방법론적으로 코칭을 활용하여 초등학생의 '자기존중, 배려 소통, 자기조절, 정직 용기'의 인성덕목을 향상시킬 수 있는 인성교육 프로그램을 개발하고, 개발된 프로그램이 네 가지 인성덕목을 향상시키는지를 검증하는 것이다. 본 연구는 실험집단과 통제집단을 무작위추출하지 않은 사전-사후 통제집단 유사실험설계를 실시하였다. 연구대상은 서울시 S구의 U초등학교 4학년 학급 31명이고, 실험집단을 대상으로 코칭기반 인성교육 프로그램을 2018년 3월 5일부터 2018년 6월 30일까지 16주 동안 총 16회기, 주 1회 40분씩 진행하였다. 프로그램 구성은 KEDI 인성검사의 인성덕목 중 '자기존중, 배려 소통, 자기조절, 정직 용기'의 항목으로 구성하였으며, 매 회기별 활동은 GROW모델과 Empowering모델을 융합하여 '인성코칭모델'을 개발하고 적용하였다. 대응표본 t-test 검증 결과, 연구반에서는 네 가지 인성덕목에서 유의확률 5% 수준에서 사후검사와 사전 검사의 차이가 유의미하였지만 비교반에서는 유의미한 차이가 발견되지 않았다. 본 연구는 코칭과 인성교육을 융합하여 개발한 본 프로그램이 초등학생의 네 가지 인성을 향상시키는 도구로 유용하게 활용되어 초등학교 인성교육에 기여했다는 점에서 의의가 있다. 향후 연구에서는 온라인 프로그램이나 CBI(Computer-Based Instruction) 등 첨단기술과 인문분야의 융합으로 새로운 부가가치를 창출하는 차원의 연구가 기대된다.