• Title/Summary/Keyword: Development factor

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The Effect of Stellate Ganglion Block on Breast Cancer-Related Infectious Lymphedema (유방암 감염성 림프부종 환자에서 성상신경절 블록이 미치는 영향)

  • Lee, Youn Young;Park, Hahck Soo;Lee, Yeon Sil;Yoo, Seung Hee;Lee, Heeseung;Kim, Won Joong
    • Journal of Hospice and Palliative Care
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    • v.21 no.4
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    • pp.158-162
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    • 2018
  • Breast cancer related lymphedema (BCRL) is one of the most intractable complications after surgery. Patients suffer from physical impairment, as well as psychological depression. Moreover, a recent study revealed that cellulitis significantly increased the risk of BCRL, and cellulitis has been suggested as a risk factor of BCRL development. We describe a patient treated with stellate ganglion blocks (SGBs) without steroid for relief of symptoms and reduction of the arm circumference of breast cancer-related infectious lymphedema in a month. We measured the arm circumference at four locations; 10 cm and 5 cm above and below the elbow crease, numeric rating scale (NRS) score, lymphedema and breast cancer questionnaire (LBCQ) score on every visit to the pain clinic. A serial decrease of the arm circumference and pain score were observed after second injection. In the middle of the process, cellulitis recurred, we performed successive SGBs to treat infectious lymphedema. The patient was satisfied with the relieved pain and swelling, especially with improved shoulder range of motion as it contributes to better quality of life. This case describes the effects of SGB for infectious BCRL patients. SGB could be an alternative or ancillary treatment for infectious BCRL patients.

The convergence Influence of nurse's emotional intelligence, Job Engagement and interpersonal relationship on moral sensitivity (간호사의 감성지능, 직무열의, 도덕적 민감성이 대인관계능력에 미치는 융합적 영향)

  • Bae, Du-Yi;Kim, Hyang-Soo;Kim, Song-Soon;Kim, Yun-Jeong
    • Journal of the Korea Convergence Society
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    • v.10 no.3
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    • pp.93-103
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    • 2019
  • This study is aiming tu clarify the factors that influence the interpersonal relationship of nurses and to use them as basic data for the development of educational programs to help nurse 's interpersonal relationship in the clinical field. The subjects were 179 nurses working at 3 hospitals B city and Y city. The results showed that the interpersonal relationship of the subjects were 3.51 points out of 5 points, emotional intelligence had 3.44 points out of 5 points, job enthusiasm was 3.15 points out of 5 points, and moral sensitivity was 4.5 points out of 7 points. The emotional intelligence (${\beta}=.551$, p = .000) was the predictor for the nurse's interpersonal relationship, and emotional intelligence was 37.3% explained by interpersonal relationship of the nurse. In conclusion, higher emotional intelligence, job engagement, and moral sensitivity of nurses showed higher interpersonal relationship, Emotional intelligence was the factor influencing interpersonal relationship. Therefore, it is necessary to develop an educational program to enhance the emotional intelligence of individual nurses to improve interpersonal skills of nurses.

Modeling and Simulation for Predicting the Impact of Hydraulic Breaker (유압 브레이커의 충격량 예측을 위한 모델링과 해석)

  • Kim, Sung-Hyun;Chung, Jaeho;Baek, Dong-Cheon;Park, Jong-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.741-749
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    • 2019
  • A hydraulic breaker attached to an excavator is a kind of constructuion equipment which is used for the disassembling of buildings, crashing road pavement, breaking rocks at quarry and etc. Therefore, the performance of the hydraulic breaker is mainly evaluated by the impact quantity and impact efficiency, which is an important factor for both the manufacturer and the user. In this paper, modeling and simulation for the prediction of the impact of the hydraulic breaker was conducted according to hydraulic pressure area and operating conditions of the hydraulic valve and piston using the commercial tools SimulationX for the 20ton hydraulic breaker which is mainly used in construction site. In order to verify the reliability of modeling and simulation, the results of previous experimental studies were compared and verified. The results of this study are expected to be useful for predicting the impact of the hydraulic breaker at the design stage before manufacturing and for studying parameters for improving the impact quantity. In addition, the manufacturer predicts that the development time and cost will be reduced through trial and error prevention by predicting the impact of the hydraulic breaker through the results of this paper.

A study on development of disaster-risk assessment criteria for steep slope -Based on the cases of NDMS in Ministry of Interior and Safety- (급경사지 재해위험도 평가 기준 개선 방안 연구 -행정안전부 급경사지 관리시스템 사례를 중심으로-)

  • Suk, Jae-Wook;Kang, Hyo-Sub;Jeong, Hyang-Seon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.372-381
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    • 2019
  • In this study, the National Disaster Management System (NDMS) was analyzed to evaluate the disaster impact assessment standards for steep slopes. Problems in the assessment methods and systems were discovered, which could be reasons for poor reliability. The disaster-risk evaluation index needs improvement to evaluate various types of retaining walls, such as concrete/reinforced soil walls and reinforcing stone masonry. Additionally, using the same score for overturning, bulging, and efflorescence could be reasons for poor reliability, and different weighting factors are needed. Assessment methods are needed to subdivide the social influence evaluation index while considering environmental conditions of steep slopes, such as railroads and reservoirs. For the evaluation of steep slopes, standards for start and end points of steep slopes should be created for effective management, and disaster impact assessment needs to be performed after redevelopment from an advanced index for protection and reinforcement. These problems were derived from a current evaluation system, so a disaster impact assessment is necessary to supplement the results of this study.

Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway

  • Park, Wonjin;Baek, Yi-Yong;Kim, Joohwan;Jo, Dong Hyun;Choi, Seunghwan;Kim, Jin Hyoung;Kim, Taesam;Kim, Suji;Park, Minsik;Kim, Ji Yoon;Won, Moo-Ho;Ha, Kwon-Soo;Kim, Jeong Hun;Kwon, Young-Guen;Kim, Young-Myeong
    • Biomolecules & Therapeutics
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    • v.27 no.5
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    • pp.474-483
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    • 2019
  • Vascular endothelial growth factor (VEGF) plays a pivotal role in pathologic ocular neovascularization and vascular leakage via activation of VEGF receptor 2 (VEGFR2). This study was undertaken to evaluate the therapeutic mechanisms and effects of the tetrapeptide Arg-Leu-Tyr-Glu (RLYE), a VEGFR2 inhibitor, in the development of vascular permeability and choroidal neovascularization (CNV). In cultured human retinal microvascular endothelial cells (HRMECs), treatment with RLYE blocked VEGF-A-induced phosphorylation of VEGFR2, Akt, ERK, and endothelial nitric oxide synthase (eNOS), leading to suppression of VEGF-A-mediated hyper-production of NO. Treatment with RLYE also inhibited VEGF-A-stimulated angiogenic processes (migration, proliferation, and tube formation) and the hyperpermeability of HRMECs, in addition to attenuating VEGF-A-induced angiogenesis and vascular permeability in mice. The anti-vascular permeability activity of RLYE was correlated with enhanced stability and positioning of the junction proteins VE-cadherin, ${\beta}$-catenin, claudin-5, and ZO-1, critical components of the cortical actin ring structure and retinal endothelial barrier, at the boundary between HRMECs stimulated with VEGF-A. Furthermore, intravitreally injected RLYE bound to retinal microvascular endothelium and inhibited laser-induced CNV in mice. These findings suggest that RLYE has potential as a therapeutic drug for the treatment of CNV by preventing VEGFR2-mediated vascular leakage and angiogenesis.

The Effect of Mother's Acceptance Parenting Attitude and Optimism on Children's Self-Regulation (어머니의 낙관성 및 수용적 양육태도가 유아의 자기조절에 미치는 영향)

  • Kim, Mi Hyang;Lee, Hyeon Jin
    • Korean Journal of Child Education & Care
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    • v.19 no.2
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    • pp.117-128
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    • 2019
  • Objective: The purpose of this study is to investigate the effect of mother's acceptance parenting attitude and optimism on children's self-regulation including cognitive, emotional, and behavioral regulation. Methods: The subjects were 361 3, 4, 5 - year - old children and their mothers who attended to the early childhood education institutions. One-way ANOVA was conducted to find out age differences in self-regulation. The regression analysis were conducted to find out whether the mother's optimism could predict their children's self-regulation. The stepwise regression analysis were conducted to find out whether the mother's acceptance parenting attitude could predict their children's self-regulation. Results: As for the self-regulation, there were significant age differences in the cognitve regulation and the behavioral regulation, but not in the emotional regulation. It implies that the abilities of cognitive and behavioral regulation increase as the age level goes up. As for the relations between mother's optimism and their children's self-regulation, only the permanence factor of the mother's optimism predicted children's cognitive, emotional, and behavioral regulation. As for the relations between mother's acceptance parenting attitude and their children's self-regulation, two components of mother's acceptance parenting attitude (unconditionally love & right) could predict children's cognitive, emotional, and behavioral regulation. The component of unique could predict the cognitive and emotional regulation. Conclusion/Implications: These results suggest that mother's optimism and acceptance parenting attitude positively affect on the development of self-regulation ability in children.

Research on the ancient iron technology of Jungwon, the center of iron industry (제철산업의 중심 중원에서 고대 제철기술을 탐구하다)

  • Do, Eui Chul;Lee, Eun Woo;Seok, Je Seop;Jang, Min Seong
    • Korean Journal of Heritage: History & Science
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    • v.48 no.1
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    • pp.148-165
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    • 2015
  • Iron was one of the most influential factors for formation and development of ancient countries. The diffusion of ironware had increased agricultural productivity and brought about military technical revolution. Needless to say, the rise and fall of the countries depended on the possession of stable iron production. Raw materials and fuels are the key factors for mass production of iron and a transportation route is essential to supply the goods. Jungwon area satisfies the three factors. There are many iron manufacture sites such as Jincheon Seokjang-ri Gusan-ri, and Chunju Chilgeum-dong Tangeumdae earthen ramparts in the Jungwon area. In order to study the ancient iron manufacture technique, reconstitution experiment was carried out using restored furnace which was made based on the Jincheon Seokjang-ri B-23 furnace. Some notable results were identified with the experiment as in the followings. Firstly, a roasting process has a connection with the decrease of hardness of the iron ore. Secondly, melting of the blast pipe as well as the formation of product within the furnace had a crucial effect on the cessation of the experiment. Thirdly, reduced iron in various locations within the furnace prove that there was enough reducing environment during the working. Not only melting point but also properties of iron can vary depending on the carbon contents. For the reason, formation of approximate environment in which iron can react to the chalcoal is the most important factor in terms of iron manufacture.

Effects of Nursing Students' Knowledge, Attitude and Nursing Professionalism on Confidence in Performance of Patient Safety (졸업학년 간호대학생의 환자안전 지식, 태도 및 간호전문직관이 환자안전 수행자신감에 미치는 효과)

  • Park, Su-Jin;Choi, Hyo-Sin;Kim, Jeong-Yun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.9
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    • pp.341-350
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    • 2019
  • This research study was conducted to investigate the effect of knowledge, attitude and nursing professionalism on the confidence of the performance of nursing students who had experience with clinical practice and also to provide basic data for the development of nursing students' curriculum. The subjects who participated in this study were 286 students in the 4th year of nursing at two colleges in the Daegu and Gyeongbuk regions. The research data was analyzed using the SPSS 22.0 program. Confidence in performance of patient safety was higher for the women than for men, and for the students of an older age and higher academic achievement. Confidence in performance of patient safety was positively related to knowledge (r=.25, p=.000), attitude (r=.39, p=.000), nursing professionalism (r=.33, p=.000) and all these had statistical significance. On the multiple regression analysis, the coefficient of determination ($R^2$) was .49 and the explanatory power of the model was 49.2% (F=24.04, p=.000). The most important factor affecting confidence in performance of patient safety was the experience of having undergone patient safety education. Based on these results, it is necessary to seek various educational methods to expand the concept of patient safety from the beginning of the undergraduate course work. Especially, we think that various education strategies such as simulation education methods or information videos are needed to develop scenarios related to patient safety.

Relationship between the Characteristics of Occupational Stress and Depression among Local Government Officials (일 지역 공무원의 직무스트레스 특성과 우울의 관련성)

  • Yoo, Seonyoung;Lee, Dayoung;Lee, Junghyun;Kim, Jiae;Jeon, Kyoungsun;Kim, Do Hoon;Sim, Minyoung
    • Anxiety and mood
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    • v.15 no.2
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    • pp.84-93
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    • 2019
  • Objective : The aim of this study was to examine the relationship between occupational stress and depression, as it is seen to be corresponding with the work characteristics of local government officials. Methods : The data of 671 local government officials who participated in this study from July to December 2015 as a part of an occupational stress management program, were analyzed retrospectively in this study. Likewise, the participants completed questionnaires, including a short form of the Korean Occupational Stress Scale (KOSS), and the Beck Depression Inventory-II (BDI-II) the results of which were evaluated and reviewed. Results : The study noted that the subscales of occupational stress related to depression were varied, according to the work characteristics of the participants, after adjusting for age and job grade. It was found that the participant's variables of job insecurity, lack of reward, organizational system and occupational climate were significantly related to the development of a depressed mood in the participant in a general sense. Notably, the factor of interpersonal conflict was significantly related to depressed mood among the general administrative group; meanwhile, lack of reward in the welfare group and insufficient job control in the technical group were significantly associated with the likelihood of developing a depressed mood in participants reviewed. In the operation and maintenance of facilities group, job insecurity was significantly related with depressed mood, whereas job demand was related more with the incidence of depression in the field work group. Conclusion : This study revealed that the influence of occupational stress on depression varied according to the occupational characteristics experienced by the participants in the work environment. These findings may be used to enhance the occupational stress management program for local government officials according to their work characteristics, to bring awareness to this issue.

Study(III) on the Development of Charts and Formulae Predicting Allowable Axial Bearing Capacity for Prebored PHC Pile Socketed into Weathered Rock through Sandy Soil Layer - The Proper Use of Long-term Allowable Compressive Load of PHC Piles by Analyzing Quality Test and Product Specifications Data - (사질토층을 지나 풍화암에 소켓된 매입 PHC말뚝에서 지반의 허용압축지지력 산정도표 및 산정공식 개발에 관한 연구(III) - 품질 성능 검사 자료 및 성능 제원 표 분석을 통한 PHC말뚝의 장기허용압축하중 성능의 올바른 활용 -)

  • Kim, Chae Min;Yun, Dae Hee;Lee, Chang Uk;Choi, Yongkyu
    • Journal of the Korean Geotechnical Society
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    • v.35 no.9
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    • pp.15-28
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    • 2019
  • Long-term allowable compressive Loads of PHC piles were analyzed based on qualification tests results by 17 small and medium PHC pile producing companies and product specifications by 6 major and 17 small and medium PHC pile producing companies. At the present stage, an average long-term allowable compressive load of PHC pile was designed at 70% level from current design data, and safety factor of 4.0 was applied to long-term allowable compressive loads of PHC pile despite of its excellent quality. Most quality standards of PHC pile are specified at KS F 4306. But compressive strength test method of spun concrete is specified at KS F 2454. As a result of analyzing quality test data supplied by each manufacturer, all quality test results showed higher performances than standard values. Therefore, it was considered that the capacity of PHC pile can be used up to the maximum allowable compressive load of PHC pile when PHC pile is designed.