• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.10
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• pp.1594-1598
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• 2015

This study was performed to investigate the effects of various acidic treatment for anthocyanin and proanthocyanidin extraction from black bean. Extracts were prepared with 80% methanol solutions containing HCl, acetic, formic, phosphoric, and citric acids of different concentrations (0.1, 0.2, 0.3, 0.5, and 0.7%). Total anthocyanin content ranged from 0.74 mg/g in 0.7% citric acid to 1.74 mg/g in 0.3% HCl, depending on acid type and concentration. The major anthocyanins were delphinidin-3-glucoside (D3G), cyanidin-3-glucoside (C3G), and petunidin-3-glucoside (Pt3G). The highest C3G content was 1.12 mg/g in 0.3% HCl. Proanthocyanidin content ranged from 2.01 mg/g in 0.5% acetic acid to 5.29 mg/g in 0.3% HCl. Thus, acidic condition is a significant factor affecting anthocyanin and proanthocyanidin extraction from black bean, and the optimum extraction conditions were determined as 80% methanol containing 0.3% HCl.

• Journal of Korean Society of Forest Science
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• v.90 no.3
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• pp.331-337
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• 2001

This study was performed to develope stem analysis program(Stemwin1.0) which can be used in PC with MS-Windows operating system. Stemwin1.0 uses width of annual tree ring measured with 1/100mm unit, and calculate increments of several growth factors such as DBH, height and volume with various methods. Mean DBH can be calculated by arithmetic and quadratic mean methods. Height can be estimated by parallel line, line extending and height curve methods. Volume can be estimated by Huber, Smalian, and Spline functions. Not only Total growth, Mean Annual Increment(MAI) and Current Annual Increment(CAI) of growth factors, but also merchantable volume and height, form factor, growth rate, and merchantable volume rate are automatically calculated. Stemwin1.0 can also output accurate stem taper curve with various scale, and prepare stem taper data(diameter at different disk heights) for statistical analysis for deriving stem taper model. Stemwin1.0 can export output data and graph to Excel for more compatible use of it.

• Journal of Korean Society of Forest Science
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• v.90 no.3
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• pp.314-323
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• 2001

This study aimed to clarify the influencing factors of mesopore ratio on a pore geometry of surface soil in coniferous stands as an index of the water retention capacity. Twenty three factors including site conditions and soil properties were analyzed by spss/pc + for the data collected during March to October of 1993. The factors influencing the mesopore ratio(pF2.7) on the surface soil were as follows; macropore ratio(pF1.6), slope, crown-cover rates, thickness of F layer, organic matter contents, and the growing stock. And influencing factor on the ratio of mesopore in the soil surface was correlated with percentage of amount of clay, soil surface, A and B horizon soil hardness shows high negative significance. Also, multiple regression equations for mesopore ratios of surface soil and surface soil hardness, clear length, growing stock, B horizon of soil hardness, organic matter contents show high significance($R^2$; 0.80). In coniferous stands, it is effective in promoting development on the ratio of mesopore that forest practice for enhancing of the water resource retention capacity should be carried out when the crown-cover rates of stands are more than 80 percentages.

• Journal of Pharmaceutical Investigation
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• v.40 no.5
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• pp.313-319
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• 2010

The objectives of this study were to evaluate the effect of formulation ingredients on the drug release and to optimize the novel sustained release matrix tablet formulations of bupropion hydrochloride. A three factor, three-level Box-Behnken design was used for the optimization procedure, with the amounts of PEO ($X_1$), citric acid ($X_2$) and Compritol 888 ATO ($X_3$) as the independent variables. The selected dependent variables were the cumulative percentage values of bupropion hydrochloride that had dissolved after 1, 4 and 8 hr. Various dissolution profiles of the drug from sustained release matrix tablets were obtained. Optimization was performed for $X_1$, $X_2$ and $X_3$ using the following target ranges; $30%{\leq}Y_1{\leq}45%$; $70{\leq}Y_2{\leq}85%$; $85%{\leq}Y_3{\leq}100%$. The optimized formulation for bupropion hydrochloride was achieved with 12.5% PEO ($X_1$), 2.5% citric acid ($X_2$) and 10% Compritol 888 ATO ($X_3$). The sustained release matrix tablets with the optimized formulation provided a release profile that was close to predicted values. In addition, the dissolution profiles of the sustained release matrix tablet with the optimized formulation were similar to those of the commercial product Wellbutrin$^{(R)}$ SR tablets ($f_2$=79.83).

• Journal of Korean Physical Therapy Science
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• v.13 no.2
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• pp.67-83
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• 2006

The present study examined that in Vivo/Vitro test is investigated in normotensive sham-operated rats (NSR) and aldosterone-analogue deoxycorticosterone acetate (DOCA)-salt hypertensive rats (ADHR) and that the antihypertensive effect was induced by silver spike point (SSP) electrical stimulation at meridian points(CV-3, -4, Ki-12, SP-6, LR-3, BL-25, -28, -32, -52), specifically, such as aldosterone in 24 hour urine analysis from healthy volunteer. The gross examination and morphometric-histological changes, such as hypertrophy, production of necrotic tissues, and the changes of cell arrangement on the kidney, and adrenal gland were markedly observed in aldosterone-analogue DOCA-salt hypertensive rats compared with those from normotensive sham-operated rats. The systolic blood pressure, weight of kidney and adrenal gland were significantly increased in ADHR than that in NSR. The required time of PSS-induced resting tone was significantly increased in ADHR than that in NSR. However, the voltage-dependent K+ (Kv) currents were significantly decreased in ADHR than that in NSR. The urine analysis showed that the concentration of aldosterone was significantly decreased in resting state from the elderly people compared with those from the adolescent healthy volunteer. The current of 1 Hz continue type of SSP electrical stimulation significantly decreased in the concentration of aldosterone of 24 hour urine from the elderly people. These results suggest that the development of aldosterone analogue-induced hypertension is associated with changed the weight of kidney and adrenal gland, blood pressure, resting tone and Kv currents, which directly affects blood pressure. Therefore, the hypertension is a risk factor on cerebrovascular disease. Moreover, these results suggest that the diminished responsiveness to SSP electrical stimulation, especially current of 1Hz continue type, in elderly people may be, in part, related by the increased of antihypertensive effects.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.23 no.5
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• pp.383-392
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• 2011

The basic research of the estuarine circulation at Gyeong-Gi bay has not been well studied up to now, although coastal development pressures have been continuously increased. To understand the oceanographic phenomena at the Han River estuary, it's essential to understand the propagation characteristic of tidal wave which is the strongest external forcing in this region. In this study, we investigate the tidal wave propagation characteristics along the 3 major channels using observation data and numerical model. It is found that 3 channels are all hyper-synchronous and the most important physical factor controlling the tidal wave propagation is topographical convergence of estuary shape and friction. The result of analytic solution at ideal channel considering the topographical convergence and friction show that the contribution of physical role of convergence and friction varies at 3 different channel. And the ratio of convergence and friction at Yeomha channel is four times larger than Seokmo channel. Because of this effect, the location of maximum amplitude at Yeomha channel is showed up downward than Seokmo channel. The ratio of decreasing amplitude and increasing phase per unit distance between stations is bigger than Seokmo channel. Although 3 major channel show a hyper-synchronous pattern, Yeomha shows more frictionally dominant channel and Seokmo channel is more dominantly affected by convergence effect.

• Journal of Distribution Science
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• v.11 no.10
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• pp.107-116
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• 2013

Purpose - Eggs are nutritionally complete and one of the most popular natural foods. Moreover, the poultry industry is one of the important food industries. However, early industrialization of the poultry industry on its own did not lead to further development compared to other livestock industries. In this study, we investigate what factors influence consumers' behavior and how consumers' understanding of retail business affects their propensity to consume. This study is different from other studies as it analyzes how the brand names of manufacturers and distribution companies affect the purchasing characteristics or actual purchase behavior of consumers in order to suggest how these manufacturers and distribution companies can increase their competitiveness. Research design, data, methodology - This study conducted a survey of 250 randomly selected egg purchasers in discount stores from January to April 2013. Consumers' purchase tendencies were calculated through frequency analysis. This result was then utilized using cluster analysis to draw a conclusion about which purchase tendency influenced consumers buying three different brands of eggs or whether this tendency really affected consumers. As a result, the outcomes of Hypotheses 2 and 3 were not clear so we drew a conclusion with our analysis of Hypothesis 1. Results - While the outcomes of Hypotheses 2 and 3 did not clearly indicate whether purchasing tendencies affected consumers when buying eggs, our analysis of Hypothesis 1 indicated that consumers were affected by the quality of the eggs rather than exterior factors such as the brand name. Thus, we concluded that it is important to promote the excellence of the quality of the eggs. Usually firms buy eggs from farms and repackage them in order to sell them. In this sense, if consumers were aware of this egg production process, and eggs were fairly distributed to retailers, large retail PB businesses would also be able to enhance their competitiveness. Conclusions - The brand, packaging, retail outlet, and other external features influenced the purchase of eggs to a certain degree, while shelf life, grade of the eggs, cleanliness, and other intrinsic characteristics had more influence. In particular, shelf life was the most important factor influencing purchase. Consumers were influenced not only by intrinsic characteristics of the eggs but also by large-scale producers' brands. Consumers relied upon the brand despite reduced competition because they found it difficult to identify shelf life and/or cleanliness. Small businesses and/or large-scale retailers can remain competitive by maintaining the freshness and cleanliness of the eggs. Further studies need to investigate areas in which consumers' cognition of the product is poor and/or the purchase inclination with regard to less developed industries such as eggs. In this study, the greatest problem was that consumers did not consume in accordance with the current situation as consumers have preferred fresh and clean eggs for a long time compared to purchase decisions based on external brands and/or packaging.

• Journal of Digital Convergence
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• v.15 no.5
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• pp.99-106
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• 2017

The purpose of this study is to analyze the relationship between tourist 's intention to use smartphone and the preceding factors through the questionnaire. For achieving this research purpose, this study surveyed the tourists who use smartphone to investigate the influence of interactivity such as two-way communication and synchronicity as hypotheses on the influence of flow, and the effect of attitude factors on continuous intention to use was analyzed by research model. In this study, a partial least squares based structural equation (PLS-SEM) method was applied to verify the hypothesis of the proposed research model. Finally, the validity of the proposed research model was confirmed through confirmatory factor analysis and hypothesis testing. Therefore, the results of this study show that interactivity and flow are influential for the reuse of users in utilizing information by using smartphone, and it affects the attitude of users in developing smart tourism system in the future. The results of this study can be utilized as basic data related to the acquisition of information by smartphone of tourists in the future development of smart tourism system.

• Journal of the Korean Geographical Society
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• v.46 no.4
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• pp.501-517
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• 2011

This research investigates a geographical issue as to which factor discovered in the only Japanese telemedicine with regard to social and medical circumstances performs a role as a determinant in regionalization, especially, local areas in Japan. According to the results, strong human networks based on regionalism are mirrored in regionalization and are associated with not only the development and management of telemedicine operations, but also the choice of telemedicine users concretely. In other words, all processes from the suggestion stage of telemedicine to the practical usage or application stage of telemedicine are involved in the existing human networks within one prefecture (the third diagnostic area); further, personal stakes are transferred to public health care services (telemedicine) and their relationships have been formulated by the telemedicine council including local government, medical association, region-rooted companies, core health centers and universities, etc. Accordingly, the telemedicine council responses to the need of telemedicine users immediately and contributes to develop regional health care. Also, telemedicine users have been connected with each other closely before operating telemedicine; accordingly, the human relationships between doctors and patients or among doctors influence the choice of telemedicine serving sites and their behaviors comes down to regional-based diagnosis via the telemedicine system.

• Journal of Microbiology and Biotechnology
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• v.30 no.5
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• pp.689-699
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• 2020

Brevibacillus brevis GZDF3 is a gram-positive, plant growth-promoting rhizosphere bacterium (PGPR) isolated from the rhizosphere soil of Pinellia ternata (an important herb in traditional Chinese medicine). The GZDF3 strain produces certain active compounds, such as siderophores, which are the final metabolite products of non-ribosomal peptide synthetase (NRPS) and independent non-ribosomal peptide synthetase (NIS) activity. With the present study, we attempted to investigate the siderophore production characteristics and conditions of Bacillus sp. GZDF3. The antibacterial activity of the siderophores on pathogenic fungi was also investigated. Optimal conditions for the synthesis of siderophores were determined by single factor method, using sucrose 15 g/l, asparagine 2 g/l, 32℃, and 48 h. The optimized sucrose asparagine medium significantly increased the production of siderophores, from 27.09% to 54.99%. Moreover, the effects of different kinds of metal ions on siderophore production were explored here. We found that Fe³⁺ and Cu²⁺ significantly inhibited the synthesis of siderophores. The preliminary separation and purification of siderophores by immobilized-metal affinity chromatography (IMAC) provides strong antibacterial activity against Candida albicans. The synergistic effect of siderophores and amphotericin B was also demonstrated. Our results have shown that the GZDF3 strain could produce a large amount of siderophores with strong antagonistic activity, which is helpful in the development of new biological control agents.