• IMMUNE NETWORK
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• v.5 no.3
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• pp.179-185
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• 2005

Background: Psoriasis is a multifactorial autoimmune skin disease with a pathogenesis that has remained obscure. Recently, T cells bearing natural killer receptors (NKRs) were precisely and strongly targeted as new putative pathogenic immunocytes in psoriasis. Among NKRs, killer cell immunoglobulin-like receptor (KIR) is the major molecule recognizing HLA class I allotypes and might be closely related to psoriasis. Methods: To investigate the association of KIR genotype and patients with psoriasis in Korean, we defined the 14 KIR genotypes in 96 patients with psoriasis and 86 healthy controls using PCR-SSP methods. Results: The frequencies of KIR2DS4 and KIR3DL1 were significantly decreased in psoriasis compared with controls (RR=0.21, p<0.02). When patients were divided into two subgroups at the age of onset, type I (<30 years) and type II ($({\geq}30$ years) respectively, these phenomena were similarly observed independent of groups divided (type I: RR=0.26, p<0.005; type II: RR=0.14, p<0.0006). When the patients were divided into subgroups according to the age of onset and family history, the frequencies of KIR2DS4, KIR3DL1, and KIR2DS3 were significantly decreased in type I compared with type II psoriasis (3DL1, 2DS4: p<0.004; 2DS3: p<0.04) and were significantly decreased in psoriasis without family history compared to with family history (3DL1, 2DS4: p<0.007; 2DS3: p<0.05). The frequency of haplotype combination BB was significantly increased in psoriasis compared with controls (RR=2.74, p<0.009). Conclusion: These results suggest that KIR genotype is a factor for the occurrence and development of psoriasis and in future how combinations of HLA and KIR genes influence psoriasis needs to be defined.

• International Commerce and Information Review
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• v.16 no.1
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• pp.25-42
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• 2014

Since the reform and opening up in 1978, Chinese economy has been increasing rapidly with a high growth rate, but after 2012 the growth rate decreased as the reform of economic system. While economy in Africa began booming since 2000. Influenced by Global Financial Crisis and European Debt Crisis, economy in Africa slightly slowed down, but it was rebounding apparently from 2010. The urgent demand for energy and the sharp increasing in foreign exchange reserve pushes China to seek overseas markets. As Africa keeps a well relationship with China and the complementarity between China and Africa economy, Africa becomes one of the target markets for China's foreign development. Recently more and more enterprises begin to invest in Africa market. But till now the study on Africa mainly focuses on theoretical research based on real cases, and empirical research are very few and need to be increased. This thesis studies the influence of enterprise feature; local market feature and investment in foreign market on the result satisfaction of Chinese enterprises that invest in Africa markets. At the same time this thesis also studies and analyzes the market access strategy and marketing strategy for Chinese enterprises after entering overseas markets and put forward effective recommendation and suggestion for these enterprises. In order to proceed this study, 317 Chinese enterprises which invest in Africa have been investigated by me. And frequency analysis, reliability analysis, factor analysis, and simple regression analysis have also been conducted by SPSS18.0 APP to verify the hypothesis. The study result suggests that onlu investment in foreign market affects the Performance satisfaction of Chinese enterprises. And the market access strategy and marketing strategy play a role of the mediational effects when Chinese enterprises are investing in Africa.

• Journal of Korea Port Economic Association
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• v.26 no.3
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• pp.259-278
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• 2010

This study analyzes the achievement of the shipping policies and the priority for the promotion of such policies, in order to consider the features of the shipping industries in Korea and other advanced shipping countries and manage the rapidly changing shipping environment actively. Based on such analysis, this study also discusses the promotional strategy to strengthen the international competitiveness of the shipping industry. Regarding the promotion of the related policies, it is necessary to establish a base for growth, strengthen a capacity of leading the market, and create an opportunity in the market. By considering such three factors, it has become known that the establishment of the market order is important for the establishment of a base for growth. It is important to consider the advancement of the shipping tax system. Also, the information-orientation and the knowledge-industrialization of the shipping industry need to be considered. In order to strengthen a capacity of leading the market, the stable security of the labor force in the shipping industry is the most important factor. Also, it is important to consider the development and the upbringing of the global mega career and the shipping business. Regarding the creation of an opportunity in the market, it is important to expand the range of the shipping exchange between South Korea and North Korea, which will influence the administrative and the operative results related with the promotion of the related policies.

• Clinical and Experimental Reproductive Medicine
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• v.20 no.2
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• pp.107-115
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• 1993

Procedures to separate motile. normal & motile and acrosome-reacted sperm with high efficiency have clinical application in Assisted Reproductive Technology in terms of increasing the probability of fertilization by a normal sperm and subsequent normal embryonic development. This study evaluated the effects of 10 sperm preparation techniques [Swim-up from a washed pellet (SU). Swim-up from semen (SO). Continuous Percoll Gradients I (PIC). Discontinuous Percoll Gradients I (PID). Continuous Percoll Gradients II(P II C). Discontinuous Percoll Gradients II(P II D), SpermPrep (SFC). Wang's tube (WT). Albumin Gradients (AG), Low temperature capacitation (LTC)] on motility (%), normal morphology (%), motile sperm recovery rate(%). morphologically normal & motile sperm recovery rate (%), true acrosome reaction (%) and fertilizing ability. A P II D proved to be an effective means of separating morphologically normal & motile sperm. Our results indicated the P II D has advantages as compared with other methods in terms of recovery rate. enhancement of motility and normal morphology. And a LTC seems to be an effective means of enhancing the true acrosome reaction and fertilizing ability. These results suggest that the combined method of LTC and P II D for separation of morphologically normal & motile sperm and acrosome reacted sperm may be a useful procedure for intrauterine insemination and in vitro fertilization in the management of male factor infertility as well as for isolation of subpopulation of sperm for basic research.

• Journal of Digital Convergence
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• v.15 no.10
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• pp.1-7
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• 2017

The purpose of this paper is to examine how multi-cultural acceptability affects the perception of necessity of unification through structural equation model. The multi-cultural acceptability, familiarity with North Korean defectors, and awareness of unification were selected as the latent variables and the full / partial mediator models were built for structural equations. The observed variables for each latent variable were data that were collected through the National Survey on the Integration of North and South Korea conducted by the Korea Institute for National Unification in 2015. As a result, the acceptance of multiculturalism had a significant effect on the intimacy of the defectors, which had a positive effect on the recognition of the need for unification. The intimacy of the defectors was more influential as a parameter for full mediation than for partial mediation. Although the consciousness of unification gets weakened by postwar generations, that the phenomenon that changes into a multicultural society plays a part in recognizing the necessity of unification. In addition, the increase of North Korean defectors may ultimately become a factor in recognizing the need for unification. This study demonstrated that increasing the acceptance of multiculturalism can increase the need for unification, which means that more research fields can be derived.

• Korean Journal of Environment and Ecology
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• v.34 no.4
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• pp.304-317
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• 2020

This study conducted selected two sites in Geumnamhonam and four sites in Honam-Jeongmaek for vegetation survey with consideration to the location environment and anthropogenic impacts to investigate the vegetation structures of the Geumnamhonam-Jeongmaek·Honam-Jeongmaek ridge areas. Using TWINSPAN (two-way indicator species analysis), each of the two ridge areas were categorized into seven plant communities. The differential species in the TWINSPAN technique indirectly represent the environmental factors of plant communities, and the community types of the two ridge areas were divided based on environmental factors such as altitudes above sea level, soil moisture, and disturbance. These results were in harmony with the environmental factors of the DCA (detrended correspondence analysis) axis 1. In the low-lying areas of both ridge areas, afforestation tree species such as Pinus rigida and P. thunbergii were in competition with native tree species. As such, in the low-lying areas, artificial vegetation disturbance was severe due to afforestation and development projects. In relatively highland areas, such as upper slopes, and top areas, in the ridge, the vegetation type with the dominance of Quercus mongolica, Q. variabilis, and P. densiflora was preserved well. As for differences between the two ridge areas, communities dominated by Q. mongolica were distributed widely in Geumnamhonam-Jeongmaek because of the altitudes above sea level, and the latitude of this ridge area are higher than those of Honam-Jeongmaek. On the other hand, communities dominated by P. densiflora were distributed along with communities dominated by Q. mongolica, and communities dominated by Q. variabilis appeared in Honam-Jeongmaek because it is adjacent to the south coast. In quantitative vegetation analysis such as TWINSPAN and DCA, changes in species composition and the extracting environmental factors that cause the changes are important. To that end, the removal of accidental emergent species, the establishment of an investigation plan that assumes environmental factors, and the selection of the optimal analytical method suitable for the characteristics of the survey data are necessary.

• Korean journal of applied entomology
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• v.45 no.1 s.142
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• pp.31-36
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• 2006

Inflammation in the brain has known to be associated with the development of a various neurologiacal diseases. The hallmark of neuro-inflammation is the activation of microglia, brain macrophage. Pro-inflammatory compounds including nitric oxide(NO) are the main cause of neuro-degenerative disease such as Alzheimer's disease. In the study, we examined whether Harmonia axyridis extracts inhibit the NO production by a direct method using Griess reagent, western blotting and by RT-PCR(Reverse Transcription-Polymerase Chain Reactionin) the gene expression of inducible nitric oxide synthase(iNOS). Distilled water$(H_2O)$ and methanol(MeOH) extracts of H. axyridis inhibited the protein expression of TNF-a(Tumor Necrosis Factor) and IL-6(Interleukin) in LPS (Lipopolysaccharide) stimulated BV-2 cells at the concentration of 100 ng/ml. Incubation of BV-2 cells with the extracts of $H_2O$ of MeOH inhibited the LPS induced NO and iNOS protein. And this inhibition of iNOS protein is concordant with the inhibition of iNOS mRNA expression. These data suggested that H. axyridis extracts may play a crucial role in inhibiting the NO production.

• Korean Journal of Agricultural Science
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• v.3 no.2
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• pp.139-144
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• 1976

To deter-mine the most reasonable method for improving of newly reclaimed soil, seven kinds of improving methods were tested and the soybean was cultivated as test crop. The results obtained are summarized as follow: The newly reclaimed soil where this experiment was carried out showed low acidity and was deficient in the humus, the phosphate, the calcium and the magnesium. Both the fused phosphate as well as the calcium was much effective to the correction of the soil acidity. The compost was the most effective source to increase the content of the humus in the soil, and also the calcium application showed a significant effect to increase the amount of humus. Not only compost but also fused phosphate were much effective to increase the content of calcium in the soil. Each factor as the calcium, the fused phosphate, the compost and the deep plowing has an effect to increase the amount of magnesium in soil significantly. The compost increased the potassium in soil. The amount of magnesium in soybean plant was significantly increased by the application of the calcium, the fused phosphate or the compost. And the calcium and the fused phosphate had an effect to increase the grain yield of soybean. The highest grain yield of soybean was taken at the treatment of N.P.K.+Compost+Calcium+Deep-plowing. The grain yield of soybean was significantly correlated with the soil acidity, the amount of the humus and the magnesium in soil and the amount of the magnesium in soybean plant.

• Journal of Digital Contents Society
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• v.16 no.2
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• pp.207-218
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• 2015

This study is to design and implement Smartphone application by applying the principles and processes of narrative therapy for the participants. The application is able for participants to fight out of the difficulty in question centered on the issue, and to be able to find a positive new stories to be evolving the story of their lives as well. Therefore, using the application will help them to live a healthier life out of the problems. As a way of currying the wounded heart of the youth, narrative therapy techniques were applied to Smartphone appliances accustomed to the youth. The youths' wounded minds will not only be easily cured but also can be a important factor in determining the direction of life. In this study, narrative flow was structured into four stages; relationships, externalization, creating new stories and strengthening the new story bsed on Doll & Doll' theory. Based on them, the Smartphone application for curing the wounded heart was designed and developed by utilizing narrative therapy techniques. The application was tested by 30 University students in Jeonbuk province in Korea and the results showed that they were satisfied with the application with relation to improving their heart health.

• Journal of Life Science
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• v.19 no.10
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• pp.1403-1409
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• 2009

The purpose of this study was to compare Obesity Age (OA) and chronological age, to calculate Obesity Age (OA), which gauges the state of obesity, and to analyze presented factors of obesity using expectant factors on middle-aged obese women. The subjects were one hundred twenty seven middle-aged obese women ($49.6\pm7.3$ yr, BMI $29.41\pm2.9$, fat $36.8\pm4.6%$) who participated in different weight loss programs three times. The body composition, physical fitness, blood pressure and blood were measured before the weight loss programs. Informed consent was obtained from all subjects before enrollment in the study. The regression equation is as follows: (1) OAS (Obesity Age Score)=$0.106*X_1+0.035*X_2+0.048*X_3+0.041*X_4+0.003*X_5-0.037*X_6-10.667$ ($X_1$: BMI, $X_2$: weight, $X_3$: %fat, $X_4$: WC, $X_5$: TG, $X_6$: $VO_{2max}$), (2) OA (Obesity Age)=7.3*OAS+49.6*(-1), (3) Z (correction factor)=(CA-49.6)(1-0.03), (4) OAc (corrected Obesity Age)=1.03*CA-7.3*OAS+1.47. The comparison of corrected Obesity Age (OAc) and chronological age did not have any differences, and the average of the OAc was close to chronological age. The correlation coefficient between the OAc and chronological age was r=0.724 (p<0.05). The equation can be utilized for middle-aged obese women, because it could evaluate the obesity-related factors by including BMI, body weight, %fat, waist circumference, triglycerides and $VO_{2max}$.