• Molecules and Cells
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• v.20 no.2
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• pp.210-218
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• 2005

The rice genome contains at least 28 EXPA (${\alpha}$-expansin) genes. We have obtained near full-length cDNAs from the previously uncharacterized genes. Analysis of these newly identified clones together with the 12 identified earlier showed that the EXPA genes contain up to two introns and encode proteins of 240 to 291 amino acid residues. The EXPA proteins contain three conserved motifs: eight cysteine residues at the N-terminus, four tryptophan residues at the C-terminus, and a histidine-phenylalanine-aspartate motif in the central region. EXPA proteins could be divided into six groups based on their sequence similarity. Most were strongly induced in two-day-old seedlings and in the roots of one-week-old plants. However, only 14 genes were expressed in the aboveground organs, and their patterns were quite diverse. Transcript levels of EXPA7, 14, 15, 18, 21, and 29 were greater in stems, while EXPA2, 4, 5, 6, and 16 were highly expressed in both stem and sheath but not in leaf blade. EXPA1 is leaf blade-preferential, and EXP9 is leaf sheath-preferential. Most of the root-expressed genes were more strongly expressed in the dividing zone. However, the Group 2 EXPA genes were also strongly expressed in both mature and dividing zones, while EXPA9 was preferentially expressed in the elongation zone. Fourteen EXPA genes were expressed in developing panicles, with some being expressed during most developmental stages, others only as the panicles matured. These diverse expression patterns of EXPA genes suggest that in general they have distinct roles in plant growth and development.

• Korean Journal of Plant Taxonomy
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• v.47 no.1
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• pp.11-22
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• 2017

Prangos fedtschenkoi (Regel et Schmalh.) Korovin (Apiaceae) is an endemic species for mountainous Middle Asia, which is both a rare and useful plant. Organic extractions from this species are being used in pharmaceutics and cosmetology. In recent years, P. fedtschenkoi distribution area has considerably decreased, presumably, resulting from human activities such as agriculture, construction works, overgrazing and collection from wild for pharmaceutic purposes. Six populations were found in Uzbekistan and their genetic divergence and differentiation were studied with 10 inter-simple sequence repeat (ISSR) markers, selected out of 101. Totally 166 amplified ISSR fragments (loci) were revealed, of which 164 were polymorphic. Relatively moderate level of polymorphism was found at population level with polymorphic bands ranging from 27.71% to 47.59%. Mean P = 39.05%, $N_a=1.40$, $N_e=1.25$, S.I. = 0.21, and $H_e=0.14$ were revealed for all loci across six populations. AMOVA showed higher variation among populations (62%) than within them (38%). The Bayesian model determined 5 clusters, or genetic groups. The posteriori distribution of the Theta II estimator detected full model identifying high inbreeding, intensified by low gene flow (Nm = 0.3954). Mantel test confined population 6 as distinct cluster corresponding to geographic remoteness (R = 0.5137, $p{\leq}0.005$). Results were used as the bases for developing conserve measures to restore populations.

• Clinical and Experimental Reproductive Medicine
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• v.26 no.2
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• pp.275-280
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• 1999

Male sexual differentiation involves a cascade of events initiated by the presence on the Y chromosome of the of the SRY (sex determining region of Y chromosome) gene, which causes the indifferent gonad to develop into a testis. Hormonal products of the testis, predominantly testosterone and Mullerian inhibiting subtance (MIS), then control the sexual differentiation of the developing fetus. SRY is a transcription factor; however, target genes for its action have yet to be identified, because the DNA recognition sequence for SRY is found in many genes. Therefore the study of intersex disorders is being used to identify other genes active in the pathway of sexual differentiation. Patients with 46,XY gonadal dysgenesis, or Swyer's syndrome, have streak gonads, normal stature, and a sexually infantile phenotype with Mullerian structures present. The inheritance is usually sporadic but can be autosomal dominant or X-linked recessive. Unlike 45,X patients, stigmata of Turner syndrome are rare. As many as 20 to 30% of patients are at risk for malignant gonadal tumor formation and should undergo gonadectomy soon after the diagnosis is made. We have experienced a case of Swyer syndrome which showed a positive SRY gene in peripheral blood and gonad. So we report this case with a brief review of literatures.

• Journal of Information Processing Systems
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• v.9 no.4
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• pp.511-537
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• 2013

Numerous data intensive applications demand the efficient processing of a new type of query, which is called a progressive query (PQ). A PQ consists of a set of unpredictable but inter-related step-queries (SQ) that are specified by its user in a sequence of steps. A conventional DBMS was not designed to efficiently process such PQs. In our earlier work, we introduced a materialized view based approach for efficiently processing PQs, where the focus was on selecting promising views for materialization. The problem of how to efficiently find usable views from the materialized set in order to answer the SQs for a PQ remains open. In this paper, we present a new index technique, called the Dynamic Materialized View Index (DMVI), to rapidly discover usable views for answering a given SQ. The structure of the proposed index is a special ordered tree where the SQ domain tables are used as search keys and some bitmaps are kept at the leaf nodes for refined filtering. A two-level priority rule is adopted to order domain tables in the tree, which facilitates the efficient maintenance of the tree by taking into account the dynamic characteristics of various types of materialized views for PQs. The bitmap encoding methods and the strategies/algorithms to construct, search, and maintain the DMVI are suggested. The extensive experimental results demonstrate that our index technique is quite promising in improving the performance of the materialized view based query processing approach for PQs.

• Nuclear Engineering and Technology
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• v.17 no.4
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• pp.256-266
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• 1985

The loss of coolant flow accident is analyzed for the pressurized water reactor of Korea Nuclear Unit-1. The loss of coolant flow accident is classified into three types in accordance with its severity; partial loss of coolant flow, complete loss of coolant flow and pump locked rotor accident. Analysis has been carried out in three stages; system transient and average core analysis, DNBR calculation and hot spot analysis. The purpose of developing KTRAN is to simulate the transient fast. For the DNBR calculation, the thermal hydraulic codes, SCAN and COBRA IV-1, are adopted. And for the hot spot analysis, the fuel thermal transient code LTRAN is employed. This code system should be fast responding to the transient analysis. In case the transient occurs, severity comes within a couple of seconds. So response should be fast to accomodate the following sequence of the accident. Unfortunately this purpose could not be achieved by KTRAN. However, the calculated results are well comparable with FSAR results in range. Thereby, the effectiveness of KTRAN code analysis in this type of accident is proven.

• Education of Primary School Mathematics
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• v.9 no.2 s.18
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• pp.89-105
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• 2005

The purposes of this study were to develop an effective teaching material for slow learners in mathematics and to investigate its effect. To achieve the first goal, several pre-used teaching material and the 7th national curriculum for elementary school mathematics were analyzed to set up a framework fur developing new teaching material. Using these developed framework and curriculum data, 370 units of lesson were developed from the 3rd grade to the 6th grade. To investigate the effect of the material, 3 slow learners (2 from the 5th and 1 from the 6th grade) were selected through diagnostic tests. Then supplementary lessons were administered after school to relieve their disability accordingly for seven months. During the lessons(lasted about 40 minutes), teacher observed the subjects in detail and .judged the teaming sequence and the learning pace. Through this observation and the test administered after the treatment, several conclusions were drawn as follow: First, the supplementary lessons using the developed teaching material helped slow learners understand mathematics and solve problems. Especially, the test scores gained on formative evaluation became higher. This might be caused by the material that enabled to relieve the disablement and the teaching method that aimed to give a meaningful mathematical experience. Second, the supplementary lessons affected positively to the affective domain of the slow learners. They convinced themselves to their mathematical ability and became active in their mathematics class. This was observed by researcher and the class teacher in their lessons. Positive attitude toward mathematics and their ability is quite important for mathematics learning especially fur slow learners in mathematics.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2005.05a
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• pp.69-74
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• 2005

Despite the advancement of knowledge and techniques, architectural design has been developed by similar method and science as the logical tool since the development of Le Corbusier's 'module'. However, in the new millenium emotional design has become a key issue and today is the turning point regarding new method for designing human space. While architecture discipline of the West focused on logic, Japan based its origin in eastern discipline has developed a unique design concept called 'metabolism' and advanced it very effectively. Since its development of the unique concept, Toyo Ito has become one of the most Influential architect in and out of Japan who devoted his design career in developing new space concept. This study is specifically focused on Ito's project by finding characteristics of his projects and analyze emotional design factors by using 5 analytical tool - experiencing the space, five senses, landmark, sequence, and scale. Ito's work between 2000-2004, such as Sendai Mediatheque, showed more visible sign of emotional design characteristics compared to the works done in 1990's. Because of the analytical studies researching those emotional design characteristics and methods, the future advancement in new space design will be possible with great success. The result proves that continuing proper analysis and research in design method will assist in approaching new space design method into more advanced realm in very efficient time period with more definite design elements to accomodate and fulfill human needs in given space.

• Journal of Microbiology and Biotechnology
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• v.22 no.2
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• pp.264-269
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• 2012

Recently, we reported that the synthetic Coprisin analog peptide 9-mer dimer CopA3 (consisted of all-L amino acid sequence) was designed based on a defensin-like peptide, Coprisin isolated from Copris tripartitus. The 9-mer dimer CopA3 (L-CopA3) had antibacterial activity and induced apoptosis in human leukemia cells via a caspase-independent pathway. In this study, all of amino acid sequences of L-CopA3 were modified to all D-form amino acids (DCopA3) to develop a more effective antimicrobial peptide. We investigated whether D-CopA3 had antimicrobial activities against pathogenic microorganisms and pro-apoptotic effects in human leukemia cells (U937, Jurkat, and AML-2). The synthetic peptide D-CopA3 had antimicrobial activities against various pathogenic bacteria and yeast fungus with MIC values in the 4~64 ${\mu}M$ range. Moreover, D-CopA3 caused cell growth inhibition, and increased the chromosomal DNA fragmentation and the expression of inflammatory cytokines, TNF-${\alpha}$ and IL1-${\beta}$, transcripts in human leukemia cells. The all-D amino acid peptide DCopA3 proved as effective as the L-CopA3 reported previously. These results provide the basis for developing D-CopA3 as a new antibiotic peptide.

• Smart Media Journal
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• v.5 no.3
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• pp.42-48
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• 2016

Recently, most of the modern people used a second mobile device(two degree mobile device). Mobile devices are affecting all areas of human life, consumer electronics, transportation, manufacturing, and finance. On this paper, we propose a model-driven development based interaction model that can be used in the development of mobile payment system, which is the latest buzzword pins of the various application fields of mobile devices Tech (Fin-Tech) sector. Using a model-driven development based models do not depend on the Platforms (PIM), we propose a model for interaction between devices which can be reused when developing mobile billing app. A model-driven development based mobile applications use the reusable of interaction models development program analyzed the bus fees automatic payment application by a beacon.

• Journal of Life Science
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• v.13 no.4
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• pp.383-389
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• 2003

A cDNA (SeMIPS) encoding myo-inositol 1-phosphate synthase has been isolated from developing sesame (Sesamum indicum L. cv. Dan-Baek) seeds and its structure and function analyzed. The SeMIPS protein was highly homologous with those from plant species (88-94%), while a much lower degree of sequence homology (60%) was found with that of human. The functional domains commonly found in MIPS protein were identified and their amino acid residues were compared with each other. Northern blot indicated that the expression of the SeMIPS gene might be organ-specifically regulated. A complementation assay based on a yeast mutant system confirmed that the SeMIPS gene encodes a myo-inositol 1-phosphate synthase (MIPS) of sesame by showing functional expression of the SeMIPS cDNA in the yeast mutants containing the disrupted INO1 gene.