• The Journal of Korea Robotics Society
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• v.19 no.2
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• pp.176-187
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• 2024

Recently, automated solutions using collaborative robots have been emerging in various industries. Their primary functions include Pick & Place, Peg in the Hole, fastening and assembly, welding, and more, which are being utilized and researched in various fields. The application of these robots varies depending on the characteristics of the grippers attached to the end of the collaborative robots. To grasp a variety of objects, a gripper with a high degree of freedom is required. In this paper, we propose a service automation system using a multi-degree-of-freedom gripper, collaborative robots, and vision sensors. Assuming various products are placed at a checkout counter, we use three cameras to recognize the objects, estimate their pose, and create grasping points for grasping. The grasping points are grasped by the multi-degree-of-freedom gripper, and experiments are conducted to recognize barcodes, a key task in service automation. To recognize objects, we used a CNN (Convolutional Neural Network) based algorithm and point cloud to estimate the object's 6D pose. Using the recognized object's 6d pose information, we create grasping points for the multi-degree-of-freedom gripper and perform re-grasping in a direction that facilitates barcode scanning. The experiment was conducted with four selected objects, progressing through identification, 6D pose estimation, and grasping, recording the success and failure of barcode recognition to prove the effectiveness of the proposed system.

• Korean Journal of Radiology
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• v.24 no.6
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• pp.574-589
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• 2023

Radiopharmaceuticals targeting prostate-specific membrane antigens (PSMA) are essential for the diagnosis, evaluation, and treatment of prostate cancer (PCa), particularly metastatic castration-resistant PCa, for which conventional treatment is ineffective. These molecular probes include [⁶⁸Ga]PSMA, [¹⁸F]PSMA, [Al¹⁸F]PSMA, [^99mTc]PSMA, and [⁸⁹Zr]PSMA, which are widely used for diagnosis, and [¹⁷⁷Lu]PSMA and [²²⁵Ac]PSMA, which are used for treatment. There are also new types of radiopharmaceuticals. Due to the differentiation and heterogeneity of tumor cells, a subtype of PCa with an extremely poor prognosis, referred to as neuroendocrine prostate cancer (NEPC), has emerged, and its diagnosis and treatment present great challenges. To improve the detection rate of NEPC and prolong patient survival, many researchers have investigated the use of relevant radiopharmaceuticals as targeted molecular probes for the detection and treatment of NEPC lesions, including DOTA-TOC and DOTA-TATE for somatostatin receptors, 4A06 for CUB domain-containing protein 1, and FDG. This review focused on the specific molecular targets and various radionuclides that have been developed for PCa in recent years, including those mentioned above and several others, and aimed to provide valuable up-to-date information and research ideas for future studies.

• Journal of Microbiology and Biotechnology
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• v.33 no.11
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• pp.1506-1512
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• 2023

Quantitative analysis of adenosine triphosphate (ATP) has been widely used as a diagnostic tool in the food and medical industries. Particularly, the pathogenesis of a few diseases including inflammatory bowel disease (IBD) is closely related to high ATP concentrations. A bioluminescent D-luciferin/luciferase system, which includes a luciferase (FLuc) from the firefly Photinus pyralis as a key component, is the most commonly used method for the detection and quantification of ATP. Here, instead of isolating FLuc produced in recombinant Escherichia coli, we aimed to develop a whole-cell biocatalyst system that does not require extraction and purification of FLuc. To this end, the gene coding for FLuc was introduced into the genome of probiotic Saccharomyces boulardii using the CRISPR/Cas9-based genome editing system. The linear relationship (r² = 0.9561) between ATP levels and bioluminescence generated from the engineered S. boulardii expressing FLuc was observed in vitro. To explore the feasibility of using the engineered S. boulardii expressing FLuc as a whole-cell biosensor to detect inflammation biomarker (i.e., ATP) in the gut, a colitis mouse model was established using dextran sodium sulfate as a colitogenic compound. Our findings demonstrated that the whole-cell biosensor can detect elevated ATP levels during gut inflammation in mice. Therefore, the simple and powerful method developed herein could be applied for non-invasive IBD diagnosis.

• Journal of Advanced Navigation Technology
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• v.28 no.4
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• pp.459-465
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• 2024

The flight control computer applied to manned/unmanned aircraft is one of the key components directly connected to the control of the aircraft, and is generally designed with a redundant architecture so that essential functions for flight can be maintained even if a failure occurs in a single channel. The operational flight program loaded on these redundant flight control computers should be designed considering a time synchronization between channels, input data selection methods from redundant sensors, and fault detection/isolation methods for channels. In this paper, we propose a redundancy management method applied to triplex compact flight control computers for advanced air vehicle. The proposed redundancy management method includes a synchronization algorithm between triplex channels, an input data voting method from sensors, a bus control right selection method for control command output, and a fault detection/isolation method for channels.

• Journal of Intelligence and Information Systems
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• v.24 no.3
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• pp.157-176
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• 2018

The purpose of this research is to develop a detection model for companies designated as administrative issue in KOSDAQ market using financial data. Administration issue designates the companies with high potential for delisting, which gives them time to overcome the reasons for the delisting under certain restrictions of the Korean stock market. It acts as an alarm to inform investors and market participants of which companies are likely to be delisted and warns them to make safe investments. Despite this importance, there are relatively few studies on administration issues prediction model in comparison with the lots of studies on bankruptcy prediction model. Therefore, this study develops and verifies the detection model of the companies designated as administrative issue using financial data of KOSDAQ companies. In this study, logistic regression and decision tree are proposed as the data mining models for detecting administrative issues. According to the results of the analysis, the logistic regression model predicted the companies designated as administrative issue using three variables - ROE(Earnings before tax), Cash flows/Shareholder's equity, and Asset turnover ratio, and its overall accuracy was 86% for the validation dataset. The decision tree (Classification and Regression Trees, CART) model applied the classification rules using Cash flows/Total assets and ROA(Net income), and the overall accuracy reached 87%. Implications of the financial indictors selected in our logistic regression and decision tree models are as follows. First, ROE(Earnings before tax) in the logistic detection model shows the profit and loss of the business segment that will continue without including the revenue and expenses of the discontinued business. Therefore, the weakening of the variable means that the competitiveness of the core business is weakened. If a large part of the profits is generated from one-off profit, it is very likely that the deterioration of business management is further intensified. As the ROE of a KOSDAQ company decreases significantly, it is highly likely that the company can be delisted. Second, cash flows to shareholder's equity represents that the firm's ability to generate cash flow under the condition that the financial condition of the subsidiary company is excluded. In other words, the weakening of the management capacity of the parent company, excluding the subsidiary's competence, can be a main reason for the increase of the possibility of administrative issue designation. Third, low asset turnover ratio means that current assets and non-current assets are ineffectively used by corporation, or that asset investment by corporation is excessive. If the asset turnover ratio of a KOSDAQ-listed company decreases, it is necessary to examine in detail corporate activities from various perspectives such as weakening sales or increasing or decreasing inventories of company. Cash flow / total assets, a variable selected by the decision tree detection model, is a key indicator of the company's cash condition and its ability to generate cash from operating activities. Cash flow indicates whether a firm can perform its main activities(maintaining its operating ability, repaying debts, paying dividends and making new investments) without relying on external financial resources. Therefore, if the index of the variable is negative(-), it indicates the possibility that a company has serious problems in business activities. If the cash flow from operating activities of a specific company is smaller than the net profit, it means that the net profit has not been cashed, indicating that there is a serious problem in managing the trade receivables and inventory assets of the company. Therefore, it can be understood that as the cash flows / total assets decrease, the probability of administrative issue designation and the probability of delisting are increased. In summary, the logistic regression-based detection model in this study was found to be affected by the company's financial activities including ROE(Earnings before tax). However, decision tree-based detection model predicts the designation based on the cash flows of the company.

• Journal of the Korean Chemical Society
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• v.55 no.1
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• pp.63-69
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• 2011

This work discusses the fabrication, development and potential response behaviors of $Ag^+$ ion-selective electrodes ($Ag^+$-ISE) based on N,N'-bis(2-hydroxybenzyl)-1,3-diaminopropane (L1) and N,N'-bis(2-hydroxybenzyl)-2,2-dimethyl-1,3-diaminopropane (L2) as carriers. The observations indicated that the resulting electrode based on L1 toward $Ag^+$ showed stable near-Nernst slope approaching 58.7 mV/dec and the optimum potential response characteristics in a linear range at least five orders of magnitude with a detection limit of $1.0{\times}10^{-6}M$. The proposed electrode displayed the preferential selectivity to $Ag^+$ against other tested cations. The excellent potential analytical characteristics could lead to the successful applications of silver assay in significant real samples, indicating that the proposed $Ag^+$-ISE showed a significant advancement of measurement capabilities. But for the electrode based on L2, the poor potential response characteristics were observed in total experiment process.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.40 no.6
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• pp.95-105
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• 2003

A novel reference point detection method is proposed by exploiting tile gradient probabilistic model that captures the curvature information of fingerprint. The detection of reference point is accomplished through searching and locating the points of occurrence of the most evenly distributed gradient in a probabilistic sense. The uniformly distributed gradient texture represents either the core point itself or those of similar points that can be used to establish the rigid reference from which to map the features for recognition. Key benefits are reductions in preprocessing and consistency of locating the same points as the reference points even when processing arch type fingerprints. Moreover, the new feature extraction method is proposed by improving the existing feature extraction using filterbank method. Experimental results indicate the superiority of tile proposed scheme in terms of computational time in feature extraction and verification rate in various noisy environments. In particular, the proposed gradient probabilistic model achieved 49% improvement under ambient noise, 39.2% under brightness noise and 15.7% under a salt and pepper noise environment, respectively, in FAR for the arch type fingerprints. Moreover, a reduction of 0.07sec in reference point detection time of the GPM is shown possible compared to using the leading the poincare index method and a reduction of 0.06sec in code extraction time of the new filterbank mettled is shown possible compared to using the leading the existing filterbank method.

• The Korean Journal of Nuclear Medicine
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• v.25 no.2
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• pp.165-176
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• 1991

The purpose of this study was to assess the ability of quantitative Tl-201 tomography to identify and localize coronary artery disease (CAD). The study population consisted of 41 patients (31 males, 10 females; mean age $55{\pm}7$ yr) including 14 with prior myocardial infarction who underwent both exercise Tl-201 myocardium SPECT and coronary angiography for the evaluation of chest pain. From the short axis and vertical long axis tomograms, stress extent polar maps were generated by Cedars-Sinai Medical Center program, and the % stress defect extent (SDE) was quantified for each coronary artery territory. For the purpose of this study, the coronary circulation was divided into 6 arterial segments, and the "myocardial ischemic score" (MIS) was calculated from the coronary angiogram. Sensitivity for the detection of CAD ($\geq50%$ coronary stenosis by angiography) by angiography) by stress extent polar map was 95% in single vessel disease, and 100% in double and triple vessel deseases. Overall sensitivity was 97%. Sensitivity and specificity for the detection of individual diseased vessels were, respectively, 87% and 90% for the left anterior descending artery (LAD), 36% and 93% for the left circumflex artery (LCX), and 71% and 70% for the right coronary artery (RCA). Concordance for the detection of individual diseased vessels between the coronary angiography and stress polar map was fair for the LAD (kappa=0.70), and RCA (kappa=0.41) lesions, whereas it was poor for the LCX lesions (kappa : 0.32). There were siginificant correlations between the MIS and SDE in LAD (rs=0.56, p=0.0027), and RCA territory (rs=0.60, p=0.0094). No significant correlation was found in LCX territory. When total vascular territories were combined, there was a significant correlation between the MIS and SDE (rs=0.42, p=0.0116). In conclusion, the quantitative analysis of Tl-201 tomograms appears to be accurate for determining the presence and location of CAD.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.33 no.2
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• pp.111-122
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• 2015

This study purposed on introducing a new automated solution for detecting railway tracks and reconstructing track models from the mobile laser scanning data. The proposed solution completes following procedures; the study initiated with detecting a potential railway region, called Region Of Interest (ROI), and approximating the orientation of railway track trajectory with the raw data. At next, the knowledge-based detection of railway tracks was performed for localizing track candidates in the first strip. In here, a strip -referring the local track search region- is generated in the orthogonal direction to the orientation of track trajectory. Lastly, an initial track model generated over the candidate points, which were detected by GMM-EM (Gaussian Mixture Model-Expectation & Maximization) -based clustering strip- wisely grows to capture all track points of interest and thus converted into geometric track model in the tracking by detection framework. Therefore, the proposed railway track tracking process includes following key features; it is able to reduce the complexity in detecting track points by using a hypothetical track model. Also, it enhances the efficiency of track modeling process by simultaneously capturing track points and modeling tracks that resulted in the minimization of data processing time and cost. The proposed method was developed using the C++ program language and was evaluated by the LiDAR data, which was acquired from MMS over an urban railway track area with a complex railway scene as well.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.4
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• pp.405-414
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• 2010

According to the statistics of SecurityFocus in 2008, client-side attacks through the Microsoft Internet Explorer have increased by more than 50%. In this paper, we have implemented a behavior-based malicious web page detection system and a blacklist-based malicious web page filtering system. To do this, we first efficiently collected the target URLs by constructing a crawling system. The malicious URL detection system, run on a specific server, visits and renders actively the collected web pages under virtual machine environment. To detect whether each web page is malicious or not, the system state changes of the virtual machine are checked after rendering the page. If abnormal state changes are detected, we conclude the rendered web page is malicious, and insert it into the blacklist of malicious web pages. The malicious URL filtering system, run on the web client machine, filters malicious web pages based on the blacklist when a user visits web sites. We have enhanced system performance by automatically handling message boxes at the time of ULR analysis on the detection system. Experimental results show that the game sites contain up to three times more malicious pages than the other sites, and many attacks incur a file creation and a registry key modification.