• Journal of the Korean Society for Library and Information Science
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• v.56 no.4
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• pp.29-49
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• 2022

The book is a footnote of life and memory, a sign of knowledge and intelligence, including divinity and reason, idols and destruction, praise and curse, arrogance and prejudice, truth and falsehood. The past emperors, monarchs, priests, and rulers have been controlled or slaughtered by censorship and prohibition, burning and destruction, etc. In ancient history, archaeology, war history, cultural history, and library and information science, many studies have been conducted on the burning and destruction of books, but the Western perspective is dominant, and there are nationalistic approaches and logical leaps. This study traced the truth about the destruction of the Royal Library of Alexandria in Egypt, destruction of the Baghdad libraries by the Mongol Empire, and burning more than 200,000 volumes of Korean historical documents of Japanese Government-General in Korea among the major bibliocausts with many mysteries and controversial issues in the East and West. As a result, the Royal Library of Alexandria is most likely destroyed under the rule of the Roman Empire. The massacre of the Baghdad library by the Mongolian army is a historical fact, not the manipulation and extreme exaggeration of western society. And Korean historical documents have been stolen and burned by the Government-General of Chōsen for 35 years and should be recognized as '200,000 + α'. Lastly, On the premise of excavating historical materials, research to investigate the truth behind the blibiocaust or libricide should be continued.

• Architectural research
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• v.13 no.3
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• pp.11-18
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• 2011

With the rapid development of computer technology and ongoing destruction of traditional buildings, more and more attention is paid to digital methods for the design and preservation of traditional buildings. Unlike 2D methods, Building Information Modeling (BIM) provides an object-oriented and parametric digital representation way for traditional building components. However, one of the main limitations currently is that parametric information cannot be exchanged between BIM software packages. Therefore each kind of software must have their own parametric library which causes extensive works. In this research, the authors developed an open BIM-based library using an XML parametric approach to solve the above problems, represented traditional components according to an XML schema, and parametrically implemented these XML files in a browser which can be accessed by users for their easy component edit and selection. And then based on the XML file of one component, implemented an Add-on in ArchiCAD for users to parametrically edit and directly utilize. Thus based on these XML files, a browser for users' view and selection purpose and an add-on for users' application purpose were developed. Future research will focus on implementing these XML files in other BIM tools like Revit and Digital Project. If the whole library was to be completed based on this XML approach, an open BIM-based library would be established that all kinds of BIM software users could apply this parametric library for easy modeling of traditional houses.

• Journal of the Korean Society for Library and Information Science
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• v.26
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• pp.113-139
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• 1994

Government archives are basic source materials in the historical study. Whereas, researches on the archives of Choson-chongdokbu have been very scant. Those archives contain information about both colonism of Japan and independent movement of Korea are comparatively well preserved at Government Archives and Record Services. Therefore, it is necessary to analyze the characteristic of archives and to evaluate the system of archival management of Choson-chongdokbu. Based on the official gazette and archives of Choson-chongdokbu, this study has revealed the division of archival work, the writing and treatment of official document, compilation and preservation, and the procedure of use and destruction. As a result of the research, the followings have been identified; 1. Archival regulations were prepared by the instructions of Choson­chongdokbu at the early days of its establishment. Inspite of several revisions, its basis was maintained until 1945. 2. Each agency had its own archival department instead of central archives. 3. The archival department of Choson-chongdokbu controlled the archival administration of headquarters and attached agencies. But the secret archives were managed by the secretarial department. 4. The writing and treatment of archives were done by the archival regulation made in 1911. 5. Each agency had set more or less different preservation period. 6. There were three ways of using archives, 1) the in-house reading 2) the loan 3) the transcriptions. The archives passed the preservation period were destroyed in accordance with the related departments.

• Journal of the Korean Society for Library and Information Science
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• v.40 no.3
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• pp.35-51
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• 2006

Prior to the 1980's, reappraisal and deaccessioning were considered as an 'anti-archival' activity. Recently. however, many archivists have come to realize that a reappraisal and deaccessioning is essential to providing better access to more important records and to strengthen and refine holdings. To develop a program with strong and well-focused holding appropriate to the Purpose and environments of archives. archives have to carry out systematic and continuing Procedure to reevaluate past appraisal. This study explores the various main issues and opinions with regard to reappraisal and deaccessioning and then. suggests the reappraisal principles and deaccessioning procedures such as return of the materials to donor. transfer to more appropriate depository, destruction of the material.

• Parasites, Hosts and Diseases
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• v.42 no.1
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• pp.35-40
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• 2004

The nfa 1 gene was cloned from a cDNA library of pathogenic Naegleria fowleri by immunoscreening; it consisted of 360 bp and produced a 13.1 kDa recombinant protein (rNfa1) that showed the pseudopodia-specific localization by immunocytochemistry in the previous study. Based on the idea that the pseudopodia-specific Nfa1 protein mentioned above seems to be involved in the pathogenicity of N. fowleri, we observed the effect of an anti-Nfa1 antibody on the proliferation of N. fowleri trophozoites and the cytotoxicity of N. fowleri trophozoites on the target cells. The proliferation of N. fowleri trophozoites was inhibited after being treated with an anti-Nfa1 polycional antibody in a dose-dependent manner for 48 hrs. By a light microscope, CHO cells co-cultured with N. fowleri trophozoites (group I) for 48 hrs showed severe morphological destruction. On the contrary, CHO cells co-cultured with N. fowleri trophozoites and anti-Nfa1 polyclonal antibody (1:100 dilution) (group II) showed less destruction. In the LDH release assay results, group I showed 50.6% cytotoxicity, and group II showed 39.3%. Consequently, addition of an anti-Nfa1 polyclonal antibody produced a decreasing effect of in vitro cytotoxicity of N. fowleri in a dose-dependent manner.

• Molecules and Cells
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• v.37 no.8
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• pp.628-635
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• 2014

2-(Trimethylammonium) ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate [(R)-TEMOSPho], a derivative of an organic chemical identified from a natural product library, promotes highly efficient megakaryopoiesis. Here, we show that (R)-TEMOSPho blocks osteoclast maturation from progenitor cells of hematopoietic origin, as well as blocking the resorptive function of mature osteoclasts. The inhibitory effect of (R)-TEMOSPho on osteoclasts was due to a disruption of the actin cytoskeleton, resulting from impaired downstream signaling of c-Fms, a receptor for macrophage-colony stimulating factor linked to c-Cbl, phosphoinositol-3-kinase (PI3K), Vav3, and Rac1. In addition, (R)-TEMOSPho blocked inflammation-induced bone destruction by reducing the numbers of osteoclasts produced in mice. Thus, (R)-TEMOSPho may represent a promising new class of antiresorptive drugs for the treatment of bone loss associated with increased osteoclast maturation and activity.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.22 no.1
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• pp.11-18
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• 2018

Objectives The incidence of degenerative diseases is increasing as society ages, and this increased the economic burden on society. Oxidative stress was also under suspicion as one of the causes. Recent studies have found that Curcuma longa Rhizoma had antioxidant, anti-inflammatory, antimutagenic, and anticancer effects. Through this study, we figure out trends in Curcuma longa Rhizoma research and evaluate the therapeutic potential of Curcuma longa Rhizoma for dementia. Methods The search was made using domestic and international internet search sites. "Naver academic," "Google scholar," "Korea institute of oriental medicine (KIOM OASIS)," "Korean traditional knowledge portal (KTKP)," "Library of Congress," "Research information sharing service (RISS)," "National Digital Science Links (NDSL)," and "Pub med" are used to search. The searched for words were "turmeric," "Curcuma longa Rhizoma," "antioxidant," and "nerve regeneration." Results It could be seen that a lot of research done on Curcuma longa recently. In previous studies, the most common research disease was cancer. In previous studies, the most common effects of Curcuma longa was antioxidant and anticancer. Curcumin, Vitamin B1, and various essential oils were the functional components of Curcuma longa Rhizoma. Curcuma longa Rhizoma performs DPPH radical scavenging activity and ABTS radical cation decolorization activity; it inhibits NO and iNOS. Conclusion The destruction of nerve cells due to oxidative stress is a cause of dementia. Curcuma longa Rhizoma have antioxidant effects. Therefore, we believed that it is an effective treatment for dementia. Various studies will be made on Curcuma longa Rhizoma.

• Journal of Microbiology
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• v.41 no.4
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• pp.295-299
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• 2003

Adenovirus (Ad) precursor to the terminal protein (pTP) plays an essential roles in the viral DNA replication. Ad pTP serves as a primer for the synthesis of a new DNA strand during the initiation step of replication. In addition, Ad pTP forms organized spherical replication foci on the nuclear matrix (NM) and anchors the viral genome to the NM. Here we identified the interferon inducible gene product 1-8D (Inid) as a pTP binding protein by using a two-hybrid screen of a HeLa cDNA library. Of the clones obtained in this assay, nine were identical to the Inid, a 13-kDa polypeptide that shares homology with genes 1-8U and Leu-13/9-27, most of which have little known functions. The entire open reading frame (ORF) of Inid was cloned into the tetracycline inducible expression vector in order to determine the biological functions related with adenoviral infection. When Inid was introduced to the cells along with adenoviruses, fifty to sixty percent of Ad-infected cells expressing Inid had rounded morphology, which was suggestive of apoptosis. Results from the terminal deoxynucleotidyl transferase (TdT) and DNA fragmentation assays confirmed that Inid induces apoptosis in Ad-infected or in uninfected cells. The Inid binding to pTP may target the cell for apoptotic destruction as a host defense mechanism against the viral infection.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.10
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• pp.687-693
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• 2013

Coastal sand dunes have been seriously damaged caused by the development thoughtless for the environment and coastal erosion and destruction due to artificial structures like coast roads and breakwater. Hereupon, in this study we made a library of rhizobacteria that have the plant growth-promoting ability for plant rhizosphere of indigenous plants inhabiting in a coastal sand dune as well as the strong tolerance to salt, and evaluated the plant growth-promoting ability of these strains. Furthermore, we evaluated the effect of rhizobacteria on the growth rate of saline tolerant plants in sandy soil; selected out the most useful micro-organism for the restoration of a damaged sand dune. The effect of inoculation of strains selected from the first experiment on the growth of Peucedanum japonicum and Arundo donaxes planted in a coastal sand dune was evaluated. As a result, Bacillus aerius MH1RS1 had plant growth promoting activities: indole acetic acid (IAA) production, siderophores and 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) activity, and also had a salinity tolerance. Also, in case of Peucedanum japonicum, the length of stems and weights of roots were enhanced by the inoculation of B. aerius MH1RS1. Fresh weights of stems and weights of roots in experimental group were, in particular, increased by 25% comparing with the control group. For an Arundo donax in experimental group, plant length increased by 18%, and weight of roots by 20% which is significant.

• Journal of the Korean Society for Marine Environment & Energy
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• v.19 no.2
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• pp.99-110
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• 2016

When a riser is damaged, the oil spills to sea. Oil spills cause huge economic losses as well as a destruction of the marine environment. To reduce losses, it is needed to predict spilled oil volume from risers and the excursion of the oil. The present paper simulated the oil spill for a damaged riser using open source libraries, called Open-FOAM. To verify numerical methods, jet flow and Rayleigh-Taylor instability were simulated. The oil spill was simulated for various damaged leak size, spilled oil volume rates, damaged vertical locations of a riser, and current speeds. From results, the maximum excursion of the spilled oil at the certain time was predicted, and a forecasting model for various parameters was suggested.