• Korean Journal of Adult Nursing
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• v.27 no.5
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• pp.493-504
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• 2015

Purpose: This study was a qualitative study to explore and understand the adaptation experiences of hemodialysis among women with End-Stage Renal Disease (ESRD) and to develop a substantive theory using the grounded theory method. Methods: Participants were 15 female patients who underwent hemodialysis for ESRD treatment from three general hospitals. The data were collected through in-depth individual interviews. Results: The adaptation experience of participants was emerged as a process of taking care and enduring. There were four adaptation stages as a negative, despair, receptive, and maintenance period in reference to hemodialysis. The causal conditions were a vague expectations of recovery and refusal to undergo hemodialysis. The core phenomenon was that of confinement to dialysis machine. The contextual conditions for this phenomenon were the loss of femininity. They used action/interaction strategies such as transition their life with a focus on hemodialysis, seeking information, and learning how to take care of their body. Through this process, they had a strong will to live or had sustained their life. Conclusion: These results indicate that there is a need for nurses to understand the different steps of adaptation experiences of the given patient population. It is necessary for nurses to support them to lead their life as much normal as possible and improve the adaptation experience of ESRD.

• Journal of Korean Academy of Nursing
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• v.47 no.3
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• pp.367-379
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• 2017

Purpose: This study aimed to understand and describe the caring experiences of spouses of elderly people with dementia. Methods: The hermeneutic phenomenological method was used and participants were 12 spouses aged 65 and over who were taking care of their husbands or wives with dementia at home. Data were collected from individual in-depth interviews on participants' actual caring experiences. Additionally, novels, movies, and memoirs on elderly couples with partner who had dementia were included as data for the analysis. The qualitative data analysis software program was used to manage and process the collected qualitative data. Data were analyzed using hermeneutic phenomenological analysis based on four fundamental existentials including lived body, lived space, lived time, and lived others. Results: Five essential themes emerged from the analysis: 1) body moving like an old machine, 2) swamp of despair filling with hope, 3) sweet time after bitterness, 4) disappointed elderly couple in the empty nest, and 5) unappreciation vs. empathetic feelings. These essential themes were comprehensively summarized as "the road leading to the maturation of life with dedication and hope while bearing the weight of caring based on the couple's relationship." Conclusion: The findings indicate that the nature of the caring experience of spouses of elderly individuals with dementia is filled with many dynamic and paradoxical dimensions. Thus, results of the study would help with developing interventions tailored specifically for elderly spouse caregivers to support their role adaptation and ultimately improving their quality of life.

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2001.12a
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• pp.22-37
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• 2001

Melatonin is secreted during the hours of darkness and is thought to influence the circadian and seasonal timing of a variety of physiological processes. Serotonin N-acetyltransferase (AA-NAT) which is found to be expressed in pineal gland, retina, and various tissues, catalyses the conversion of serotonin to N-acetylserotonin and is known as the rate-limiting enzyme in the biosynthetic pathway of melatonin. The compounds that modulate the activity of AA-NAT can be used to treat serotonin-and melatonin-related diseases such as insomnia, depression and seasonal affective disorders (SAD). Several assay methods have been developed by which to measure AA-NAT activity. We have also developed a simple, rapid and sensitive AA-NAT assay method that takes advantage of differences in the organic solubilities between acetyl CoA and N-acetyltryptamine. We screened modulators of AA-NAT activity from the water extracts of the medicinal plants. We found MNP1005 which strongly inhibited the activity of AA-NAT ($IC_{50}$=2.2$\mu$M). Enzyme inhibitory kinetic studies revealed that MNP1005 exhibited a noncompetitive inhibition toward tryptamine. The antidepressant effect of MNP1005 was investigated on behavioral despair test so called forced swimming test (FST). MNP1005 significantly increased swimming behavior by reducing immobility with treatment of 10 mg/kg when compared to the vehicle-treated control group (P < 0.05). This suggests that MNP1005 possesses antidepressant activity. The influence of chronic MNP1005 treatment on the expression of brain-derived neurotrophic factor (BDNF) was examined by in situ hybridization and Northern blot. Chronic treatment of MNP1005 blocked the downregulation of BDNF mRNA in the frontal cortex and other cortex regions in response to restraint stress.

• Journal of Korean Biological Nursing Science
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• v.17 no.1
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• pp.37-43
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• 2015

Purpose: Stress, depending on its intensity and duration, results in either adaptive or maladaptive physiological and psychological changes in humans. Also, it was found that stressful experiences increase the signs of behavioral despair in rodents. On the other hand, exercise and melatonin treatment is believed to have many beneficial effects on health. Thus, this study was designed to evaluate the anti-depressant effects of physical activity and melatonin against chronic stress-induced depression in rats. Methods: Adult male Sprague-Dawley(SD) rats(200-250g, 7 weeks of age) were subjected to depression induced by chronic stress. Chronic depression was induced with forced-swim stress (FSS) and repeated change of light-dark cycle for 4 weeks. In the last 2 weeks, some rats were confined in a cage enriched with a running wheel, seesaw and chewed a ball from 19:00 to 07:00 every day. Melatonin was injected intra-peritoneally (I.P), and the rats received intraperitoneal injections of melatonin (15 mg/kg). The Forced Swim Test (FST) was performed to evaluate the immobility behaviors of rats for a 5 min test. Results: It was found that, the immobility time in FST was significantly (p<.05) lower in physical exercise ($M=58.83{\pm}22.73$) and melatonin ($M=67.33{\pm}37.73$) than in depressive rats ($M=145.93{\pm}63.16$) without physical activity. Also, TPH positive cell in dorsal raphe was significantly (p<.05) higher in exercise ($M=457.38{\pm}103.21$) and melatonin ($M=425.38{\pm}111.56$) than in depressive rats ($M=258.25{\pm}89.13$). Conclusion: This study suggests that physical activity and melatonin produces antidepressant-like effect on stress-induced depression in rats. So, physical exercise and melatonin may be a good intervention in depression patients.

• Research in Community and Public Health Nursing
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• v.6 no.2
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• pp.133-160
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• 1995

The purpose of this study was to understand the structure of the lived experience by poor elderly people. The research question was 'What is the structure of the lived experience of life of a poor elderly people.' The sample consisted of 21 single poor elderly persons in Pusan. The unstructured interviews were audio-recorded and analyzed using the Van Kaam method. This study was 368 responses which yielded of descriptive expressions and priority classifications. The result generated 74 common elements, 18 syntheses of hypothetical definitions and 5 identifications of the structural definition. The structural definitions and hypothetical definitions were as follows; 1. physical discomfort ; complaints of severe pain ; dysfunction of physical organs 2. emotional cognition ; despair ; resignation ; attitude toward death 3. support system ; interaction with family ; thinking about God ; economical difficulties ; expectancy of social services ; opinions about health service ; leisure ; interaction with neighborhood ; dissatisfaction due to inadequate environment 4. past reminiscence ; negative reminiscence of one's past ; past regret ; positive reminiscence of one's past 5. desire ; desire of unrealization life ; self satisfaction The significance of this study for nursing are; Comprehension of the lived experience of client and identification' of nursing approach method concerning the lifestyle of client.

• Journal of the Korean Society of School Health
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• v.28 no.1
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• pp.1-9
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• 2015

Purpose: The purpose of this study is to examine the effect of sleep duration on suicidal ideation in Korean adolescents. Methods: This study used the data drawn from Korea Youth Risk Behavior Web-Based Survey in 2013. A total data of 63,301 adolescents were included in the analysis. Included variables were general characteristics, health status variables, hours of sleep, and suicidal ideation. For sample description weighted percentage and means were used. Rao-Scott ${\chi}^2$ test and simple and multiple logistic regression with dummy variables were conducted with use of SAS 9.2. Results: Among general characteristics and health status variables, gender, grade, school level, school achievement, family's economic status, living with parents, subjective health, happiness, stress, and feeling of despair were found to be significantly related to suicidal ideation. Rates of having suicidal ideation were 22.4% in the case of students with less than 5 hours of sleep and 12.9% in students with 8 or more hours of sleep. After controlling general characteristics and subjectively perceived variables, hours of sleep was still significantly related to suicidal ideation. That is, compared to adolescents with 8 hours or more of sleep, those with less than 5 hours of sleep showed significantly higher risk for having suicidal ideation (adjusted odds ratio: 1.20, p<.001). Conclusion: These findings suggest that short sleep has negative effects on psychological health in adolescents. Particularly, less than 5 hours of sleep has harmful effect on adolescents' increased risk for having suicidal ideation.

• Anxiety and mood
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• v.6 no.1
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• pp.65-70
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• 2010

Objectives : Indirect contact with trauma may occur when a person empathically listens to detailed descriptions, exposing the person to intense emotional pain from trauma victims. Although less severe than direct trauma, indirectly traumatized persons may experience the same fear, rage, and despair as direct trauma victims. This phenomenon has been variously termed vicarious trauma, traumatic countertransference, burnout, compassion fatigue, and secondary traumatic stress. Using a psychiatric symptoms questionnaires, this study investigated the effects of indirect exposure to co-worker's trauma on the mental health of firefighters who had not directly experienced traumatic events in the previous year. Methods : We administered self-report questionnaires, such as the Impact of Event Scale-Revised (IESR) and Alcohol Use Disorder Identification Test (AUDIT), to firefighters working at two fire stations in a metropolitan city. We analyzed 188 of 232 collected surveys, after excluding falsely entered data (28 cases) and questionnaires by directly-traumatized victims (16 cases). Results : Alcohol consumption and posttraumatic stress disorder (PTSD) symptoms, as determined by the AUDIT and IES-R, were significantly higher in the indirectly-traumatized group. The ratio of high-risk members scoring higher than 23 in IES-R was larger in the indirectly traumatized group, although this was not statistically significant. Conclusion : Alcohol consumption was significantly higher in the indirectly traumatized group. This group also included more members at high risk for PTSD. Further research, with a larger group of indirectly traumatized firefighters and ongoing investigation of PTSD development and other psychiatric symptoms, is needed.

• Human Ecology Research
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• v.57 no.3
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• pp.329-340
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• 2019

The 'Sliver-Spoon-Discourse' is currently witnessing growing complaints about the polarization and a sense of despair among many young people in Korean society. The 'Sliver-Spoon-Discourse' that compares one's subjective socioeconomic status to a spoon implies a sense of psychological superiority or deprivation. The present study empirically tested the current popular 'Sliver-Spoon-Discourse' based belongingness and explored how subjective socioeconomic status may affect the psychology of young people. This study examined the effects of subjective socioeconomic status on individual relative deprivation and subjective well-being. Data were collected from 307 undergraduate students enrolled at universities located in Seoul with both parents alive. The findings of this study were as follows. First, student respondents reported moderate levels of subjective socioeconomic status, relative deprivation, and subjective well-being. Second, after controlling for respondents' gender, age and family income, the students' subjective socioeconomic status was negatively associated with their level of relative deprivation. Finally, after controlling for respondents' sociodemographic characteristics, the students' subjective socioeconomic status was not significantly related to all the three sub-factors of life satisfaction, positive emotion and negative emotion as well as total subjective well-being. The results indicate that 'Sliver-Spoon-Discourse' based belongingness may instigate relative deprivation of young people without affecting their subjective well-being. The implications of the results are discussed for youth programs and policies.

• The Journal of the Korea Contents Association
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• v.19 no.7
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• pp.110-119
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• 2019

is a movie about the frustration and the despair of young people in Korean society today. It is different from the previous Lee Chang-dong's film in that it provides the main character's perception and feelings about the world as the ultimate cause of the protagonist's actions. Lee Chang-dong's characters begin to change from . The main character of Burning goes one step further. He seems to believe that the main character's only weapon to overcome the logic and constraints of reality is obsessive and compulsive behaviors. Unlike previous movies, the character in Burning is a person who practices awareness and proves his character through action. I will analyze characters in to suggest the change of film form. Especially I will look at how the character's actions and the writer's own voice can meet and what results it bring about in this movie. It will lead to his changes in film form and an idea on the young people in Korean society today.

• 한국사회정책
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• v.25 no.3
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• pp.209-245
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• 2018

In this study, we examined at what level young people perceive their level of life and the overall degree of happiness in their lives, and empirically analyzed the factors affecting them through multiple regression and ordered logit models. As a result of the analysis, young people were more aware of the degree of overall happiness than their perception of their lives. It has been confirmed that the factors affecting the young generation's perception of the level of life and the degree of happiness are different and different factors are working on each group. In addition, it has been found that the subjective factors of psychological and emotional characteristics have a greater influence than the objective factors of social and demographic characteristics at the level of awareness of life and happiness level. However, in the case of the youth group, it was found that objective factors such as job satisfaction are the determinants that have the greatest influence on life awareness and happiness. The tendency to paradoxically respond to the current level of happiness due to despair of the future has been found to be seen in some subgroups(middle income plus working group) rather than in the whole youth generation.