• Nutrition Research and Practice
• /
• 제10권1호
• /
• pp.115-124
• /
• 2016

BACKGROUND/OBJECTIVES: This is the first study to identify common genetic factors associated with the basal metabolic rate (BMR) and body mass index (BMI) in obese Korean women including overweight. This will be a basic study for future research of obese gene-BMR interaction. SUBJECTS/METHODS: The experimental design was 2 by 2 with variables of BMR and BMI. A genome-wide association study (GWAS) of single nucleotide polymorphisms (SNPs) was conducted in the overweight and obesity (BMI > $23kg/m^2$) compared to the normality, and in women with low BMR (< 1426.3 kcal/day) compared to high BMR. A total of 140 SNPs reached formal genome-wide statistical significance in this study (P < $1{\times}10^{-4}$). Surveys to estimate energy intake using 24-h recall method for three days and questionnaires for family history, a medical examination, and physical activities were conducted. RESULTS: We found that two NRG3 gene SNPs in the 10q23.1 chromosomal region were highly associated with BMR (rs10786764; $P=8.0{\times}10^{-7}$, rs1040675; $2.3{\times}10^{-6}$) and BMI (rs10786764; $P=2.5{\times}10^{-5}$, rs10786764; $6.57{\times}10^{-5}$). The other genes related to BMI (HSD52, TMA16, MARCH1, NRG1, NRXN3, and STK4) yielded P < $10{\times}10^{-4}$. Five new loci associated with BMR and BMI, including NRG3, OR8U8, BCL2L2-PABPN1, PABPN1, and SLC22A17 were identified in obese Korean women (P < $1{\times}10^{-4}$). In the questionnaire investigation, significant differences were found in the number of starvation periods per week, family history of stomach cancer, coffee intake, and trial of weight control in each group. CONCLUSION: We discovered several common BMR- and BMI-related genes using GWAS. Although most of these newly established loci were not previously associated with obesity, they may provide new insights into body weight regulation. Our findings of five common genes associated with BMR and BMI in Koreans will serve as a reference for replication and validation of future studies on the metabolic rate.

• Asian Journal of Business Environment
• /
• 제1권1호
• /
• pp.13-20
• /
• 2011

This study is conducted to verify existing differences in consumer attitude according to distributor type and PB product type. Pre-test was conducted for this study in order to select the distributor and to classify the product type, FGI was conducted with 10 graduate students of K university in Kyong-gi. This study survey housewives, office workers, and university students excluding the participants in the pre-test. In the final analysis, research hypothesis is verified through the data of 280 answers in Korea. This research is conducted with a factor design of 3 types of distributors -department store, discount store, convenience store-and 2 types of product -utilitarian product, hedonic product. To verify the hypotheses, ANOVA is carried out. Reliability test of each measurement variables, Cronbach α coefficient is used. For each analysis, SPSS Windows 15.0 statistical program is used. The findings suggest that First, according to the size and characteristics, distributors are classified into department stores, discount stores, and convenience stores and it is verified whether if there are differences in consumers' attitude (product attitude, brand attitude and purchase intention) by the effect of different distributors. Results showed that product attitude is statistically significant. Second, product type is classified by two categories according to whether the product seeks for practicality or emotional pleasure - Utilitarian product and Hedonic product. In this context, the result after verifying whether if there is difference in the attitudes -product attitude, brand attitude, and purchase intention - in accordance with the product types is shown that utilitarian products makes bigger difference compared to hedonic products. Third, it is confirmed that there is interaction effect between product attitude and purchase intention according to the distributer type and product type. However, we find that in terms of brand attitude, there is no interaction effect. The implications of this research is as the following. First, we propose the need of PB product development and marketing strategy, which considers the product types in accordance with the scale and features of each distributor. Second, PB products should break away from the simplicity of standardized products and consider the different features of distributors. Distributors will be in need of a strategy to build a compelling brand that can differentiate itself from other distributors. This will contribute to the improvement in reliability and formation of product value.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• 제20권8호
• /
• pp.514-522
• /
• 2019

This study, two-group pretest-posttest design was to provide the well-dying program for aged and college students and to determine the effects on death anxiety, perception of good death, and readiness for death. The subjects were 14 aged and 9 college students by providing a 12 hour well-dying program, verified its effectiveness. Data collection was from October 1 to December 31, 2018 and were analyzed using IBM SPSS 24.0. To verify the normality of the research variable in two groups, Shapiro-Wilk was used. Tested by Fisher's exact probability test, independent sample t-test, and Mann-Whitney test to verify the homogeneity of general characteristics of the subjects. Repeated Measure ANOVA, Friedman test to verify the continuity of the program effects on two group respectively. Results, death anxiety and perception of good death among the aged and college students showed no significant interaction between time and group, but there was a significant difference according to time((p<.030). Readiness for death was significant interaction between time and group((p=.030), a significant difference between the groups(p=.003). The well-dying program of this study is helps raise the death anxiety and perception of good death of the subject, especially the program which helps the readiness for death of the aged.

• Asian-Australasian Journal of Animal Sciences
• /
• 제32권6호
• /
• pp.865-873
• /
• 2019

Objective: The study was designed to investigate the effects of restraint method, restraint duration, and body weight on stress-linked hormones (corticosterone, adrenaline, and noradrenaline), blood biochemical (namely glucose and lactate), and the meat quality in broiler chickens. Methods: A total of 120 male broiler chickens (Cobb 500) were assigned to a $2{\times}3{\times}2$ factorial arrangement in a completely randomized design using two restraint methods (shackle and cone), three durations of restraint (10, 30, and 60 s), and two categories of live body weight ($1.8{\pm}0.1kg$ as lightweight and $2.8{\pm}0.1kg$ as heavyweight). Results: Irrespective of the duration of restraint and body weight, the coned chickens were found to have lower plasma corticosterone (p<0.01), lactate (p<0.001), lower meat drip loss (p<0.01), cooking loss (p<0.05), and higher blood loss (p<0.05) compared with their shackled counterparts. The duration of restraint had significant effects on the meat initial pH (p<0.05), ultimate pH (p<0.05), and yellowness (p<0.01). The lightweight broilers exhibited higher (p<0.001) blood loss and lower (p<0.05) cooking loss compared to the heavyweight broilers, regardless of the restraint method used and the duration of restraint. However, the interaction between the restraint method, duration of restraint, and body weight contributed to differences in pre-slaughter stress and meat quality. Therefore, the interaction between the restraint method and the duration of restraint affected the meat shear force, lightness ($L^*$) and redness ($a^*$). Conclusion: The duration of restraint and body weight undoubtedly affect stress responses and meat quality of broiler chickens. Regardless of the duration of restraint and body weight, the cone restraint resulted in notably lower stress, lower meat water loss, and higher blood loss compared to shackling. Overall, the findings of this study showed that restraint method, duration of restraint, and body weight may affect the stress response and meat quality parameters in broilers and should be considered independently or interactively in future studies.

• Journal of the Korea Computer Graphics Society
• /
• 제25권3호
• /
• pp.11-20
• /
• 2019

In this study, a novel virtual reality (VR) experience environment is proposed for enabling walking adaptation of visually impaired people. The core of proposed VR environment is based on immersive walking interactions and deep learning based braille blocks recognition. To provide a realistic walking experience from the perspective of visually impaired people, a tracker-based walking process is designed for determining the walking state by detecting marching in place, and a controller-based VR white cane is developed that serves as the walking assistance tool for visually impaired people. Additionally, a learning model is developed for conducting comprehensive decision-making by recognizing and responding to braille blocks situated on roads that are followed during the course of directions provided by the VR white cane. Based on the same, a VR application comprising an outdoor urban environment is designed for analyzing the VR walking environment experience. An experimental survey and performance analysis were also conducted for the participants. Obtained results corroborate that the proposed VR walking environment provides a presence of high-level walking experience from the perspective of visually impaired people. Furthermore, the results verify that the proposed learning algorithm and process can recognize braille blocks situated on sidewalks and roadways with high accuracy.

• Journal of the Korean Society of Radiology
• /
• 제13권3호
• /
• pp.319-324
• /
• 2019

A depth-encoding detector module with silicon photomultipliers(SiPMs) using two layers of scintillation crystal array was designed, and the position measurement capability was verified using DETECT2000. The depth of interaction of the crystal pixels with the gamma rays was tracked through the image acquired with the combination of surface treatment of the crystal pixels and reflectors. The bottom layer was treated as a reflector except for the optically coupled surfaces, and the crystals of top layer were optically coupled each other except for the outer surfaces so that the light sharing was made easier than the bottom layer. Flood images were obtained through the combination of specular reflectors and random reflectors, grounded and polished surfaces of crystal pixels, and the positions at which layer images were generated were measured and analyzed. The images were reconstructed using the Anger algorithm, whose the SiPM signals were reduced as the 16-channels to 4-channels. In the combination of the grounded surface and all reflectors, the depth positions were discriminated into two layers, whereas it was impossible to separate the two layers in the all polished surface combinations. Therefore, using the combination of grounded surface crystal pixels and reflectors could improve the spatial resolution at the outside of the field of view by measuring the depth position in preclinical positron emission tomography.

• Journal of Digital Convergence
• /
• 제17권9호
• /
• pp.185-192
• /
• 2019

The introduction of smart technology provides accuracy, safety, and efficiency to both physicians and patients. Although interest in a clear aligner is increasing among users worldwide, the current clear aligner requires a visit to the hospital every one or two weeks for replacement, which is a very cumbersome process. There is also confusion among dentists and patients because about 40 to 80 devices are made, and calibration is done based on the order and duration of the clear aligner. Therefore, this study designed and developed a clear aligner management system so that communication between the patient and dentist can be smoothly performed by inserting the QR code into the transparent correction device. As a result, the size of the QR code was recognized as $6{\ast}6mm^2$ which can be used in the oral and the recognition distance was 100% within 12 cm. Since the dentist can remotely manage the patient with the proposed system and improve the correction effect, it is possible to manage patients abroad, as well as domestically.

• Korean Journal of Heritage: History & Science
• /
• 제54권3호
• /
• pp.106-125
• /
• 2021

This paper presents several reasons for the necessity of archaeological hands-on training and strategies for its implementation. First, it is necessary to produce a specialized manual for local cultural heritage education that can enhance the specialization and educational effectiveness of archaeological experience education. In addition, in order to secure professionalism in hands-on education and conduct it systematically, the ability of instructors to conduct education is important, so instructor competence reinforcement education needs to be conducted regularly. In addition, hands-on education needs a strategy of planning and content development of archaeological education programs, with consideration given to the subjects of learning, and the establishment of a cooperative network. It is time to cooperate with various experts to establish an education system necessary for cultural heritage education in the region and develop customized content for local archaeological heritage supplementary textbooks. Finally, due to Covid-19, we agonized over effective education plans for online archaeological heritage education, which requires active interaction class design and a strategy to promote interaction between professors and learners. In addition, such archaeological heritage education should be compatible with the goal of providing customized lifelong education.

• The Korean Journal of Franchise Management
• /
• 제10권1호
• /
• pp.43-52
• /
• 2019

Purpose - Many companies use the Internet to conduct their business to maintain and acquire their customers. SNS is used as a site where users can create profiles, build personal networks, and then share and exchange information with others. Not only do people use SNS for their self-promotion, but they also promote their services by creating SNS pages. SNS is recognized as a medium for implementing effective advertising strategies and is being used as an important means of promoting the company. Therefore, in this study, we investigate the effect of SNS marketing characteristics of restaurant franchise firms on utilitarian value and hedonic value and examine their effects on purchase intention. Research design, data, and methodology - The data were collected from 20s-60s respondents who have used SNS for restaurant visit using Google survey. A total of 159 responses were collected and used for final analysis. Smart PLS 3.0 was used for the hypothesis test. Results - As a result of an analysis, it was shown that the influence of the playfulness and affordability of information on the utilitarian value had a significant positive effect. Interaction and up-to-date did not have a positive effect on utilitarian value. Interaction, affordability, and up-to-date have no significant positive effects on hedonic value. The playfulness of information has a positive effect on the hedonic value. Both utilitarian value and hedonic value had positive effects on purchase intention. Conclusions - The findings of this study suggest that the SNS marketers of restaurant franchisors should focus on the playfulness, affordability, and up-to-date rather than the interactivity of SNS. In marketing through SNS, the act of presenting the basis of information and enhancing the provision of information through objective criteria makes it possible to experience the practical value of information. It is necessary to develop differentiated contents which cause customers interest and fun and to induce many customers' purchase intent by providing objective and realistic information. In order to increase the customers' repurchase intentions toward the food service business, customers should maximize the hedonic value and practical value felt through information. It should also focus on providing information that customers are receptive to, rather than providing prompt information.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• 제34권4호
• /
• pp.243-254
• /
• 2021

In this study, the conservatism of the response displacement method (RDM) for the seismic response analysis of box-shaped power cable tunnels was evaluated. A total of 50 examples were used considering the cross-sections of 25 power cable tunnels and two soil conditions for each power cable tunnel. The following three methods were applied for the analysis by the RDM: (1) single cosine method, (2) double cosine method, and (3) dynamic free-field analysis method. A refined dynamic analysis method considering soil-structure interaction (SSI) was employed to compare the conservatism of the RDM. The double cosine method demonstrated the most conservative result, while the dynamic free-field analysis method yielded the least deviation. The soil stiffness reduction factor, C, for the double cosine method was recommended to be 0.9 and 0.7 for the operational performance and collapse prevention levels, respectively, to ensure a probability of at least 80% that the member force by the RDM is larger than that of dynamic SSI analysis.