• Title/Summary/Keyword: Design Environments

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Expression of Fas and TNFR1 in the Luteal Cell Types Isolated from the Ovarian Corpus Luteum

  • Kim, Minseong;Lee, Sang-Hee;Lee, Seunghyung;Kim, Gur-Yoo
    • Biomedical Science Letters
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    • v.25 no.1
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    • pp.107-112
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    • 2019
  • The corpus luteum (CL) is composed to various cells, such as luteal steroidogenic cells (LSCs), luteal thecal steroidogenic cells (LTCs), luteal endothelial cells (LECs), fibroblast, immune cells and blood cells. The life span of CL is controlled by proliferation and apoptosis of luteal cells. Therefore, this study investigated apoptotic factors in luteal cells derived from bovine CL. The CL tissues were collected from bovine ovaries and luteal cells were isolated from middle phase CL. Then, LTCs and LECs were separated according to cellular morphology from LSCs. The expression of Bax, Bcl-2, Fas and tumor necrosis factor 1 receptor (TNF1R) mRNA and protein were analyzed using quantitative RT-PCR and western blot. Results show that, Bax and TNFR1 mRNA expression were significantly increased at late group than early and middle groups, otherwise Bcl-2 were significantly decreased at late group than early group (P<0.05). Fas mRNA expression were significantly decreased in middle group compared to early and late groups (P<0.05). In addition, Bax and Bcl-2 mRNA in LTCs was lower than LSCs, Fas mRNA was higher than LSCs. The Bcl-2 protein expression was lower at LTCs than LSCs, especially Fas protein in LTCs was significantly lower than LSCs and LECs (P<0.05). Otherwise, TNFR1 protein of LTCs were similar with LSCs but higher compared with LECs. In conclusion, we suggest that the results may help understanding of apoptosis ability in luteal cells according to cell type during CL regression of estrous cycle.

Development of Infrared Target for Dual-Sensor Imaging Seeker's Test and Evaluation in HILS System (이종센서 영상탐색기 시험평가를 위한 적외선 표적원 개발)

  • Park, Changhan;Song, Sungchan;Jung, Sangwoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.11
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    • pp.898-905
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    • 2018
  • In this work, infrared targets for a developed hardware-in-the-loop simulation(HILS) system are proposed for a performance test of a dual-sensor imaging seeker equipped with an infrared and a visible sensor that can lock and track for ground and air targets. This integrated system is composed of 100 modules of heat and light sources to simulate various kinds of target and the trajectory of moving targets based on scenarios. It is possible to simulate not only the position, velocity, and direction for these targets but also background clutter and jamming environments. The design and measurement results of an infrared target, such as the HILS system configuration, developed for testing and evaluation of a dual-sensor imaging seeker are described. In the future, it is planned to test the lock-on and tracking performance of an imaging seeker equipped with single or dual sensors dynamically in real time based on a simulation flight scenario in the developed HILS system.

Design of Integrated Safery System for Sealed Places (밀폐된 공간을 위한 통합안전시스템의 설계)

  • Jeong, Min-Seung;Lee, Chang-Shin;Cho, Woo-Hyeon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.23 no.1
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    • pp.97-102
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    • 2019
  • Disaster accidents at industrial sites have been increasing every year. In shipyards there are countless enclosed spaces causing issues like harmful-toxic gases stuck in those sealed areas. And due to such special and complicated structures of the working places with many layers of walls separating each other, there exist more issues of communication with workers trapped inside when accidents happen. Under this circumstance there must be a huge difficulty to evacuate or rescue the workers in case of any disaster. Therefore, in this paper, We would like to introduce the "integrated safety system" to more effectively deal with the problems and prevent such disasters in tough working environments. The suggested integrated safety system can prevent accidents in advance because it can control the data on the location of the workers in real time and the numerical values such as gas, oxygen, and carbon dioxide generated in the workplace in real time.

Building a New Smart City: Integrating Local Culture and Technology (지역문화와 기술이 융합된 새로운 스마트시티 구축)

  • Sim, Keebaik;Hwang, Woo-Sung;Choi, Myung-Ryul
    • Journal of Digital Convergence
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    • v.17 no.9
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    • pp.193-198
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    • 2019
  • In smart cities around the world, urban environments have become more convenient due to information and communication technology(ICT). However, extant studies reveal that the level of life satisfaction of citizens has not improved compared to that of the pre-smart city and citizens are skeptical about the role of the smart city. This is largely because local culture and needs were neglected during the planing and development of the smart city. The research was conducted on Cambodia as a pilot site and our findings indicate that middle age group's population is significantly small and the society is at risk of losing its culture. Therefore, this paper opens up various ways of embedding cultural programs using technology in order to pass down cultural heritage to young generation, provide an emotional attachment to the inhabitants and further build up a new phase of cultural legacy. This will engender cultural uniqueness to the city and intrigue tourists around the world resulting in the growth of the tourist industry. This research will contribute locally by providing a sense of community to the public and globally by suggesting applicable methodology to other cities that are under the similar context.

Physiological and Psychological Effects of Wearing Winter Cap in Elderly Males (고령 남자의 겨울철 모자 착용 효과 -생리·심리적 검토-)

  • Park, Joonhee;Lee, Joo-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.43 no.3
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    • pp.405-415
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    • 2019
  • This study examined the physiological and psychological effects of wearing a winter cap at rest in a cold environment. Seven older males participated in two separate trials: wearing a winter cap (CAP) and non-wearing a winter cap (CON). The experiment was conducted for 60 min in a climatic chamber (air temperature $7.8{\pm}0.3^{\circ}C$ with $43{\pm}2%RH$) with sedentary posture. Microclimate temperature at the vertex of the head was $6.88^{\circ}C$ higher in CAP compared to CON (p<.01). Microclimate humidity at the vertex was lower in CAP than in CON only during the last 5 min (p<.01). Skin temperature at the forehead in CAP was higher than in CON (p<.01). During the last 5 min, rectal temperature was higher in CAP than that in CON (p<.05). Unlike CAP, the heart rate in CON during the last 5 min decreased significantly compared to the initial 5 min (p<.05). Subjects also felt less cold on the head/face in CAP than that in CON (p<.01). The results indicate that wearing a cap for elderly males positively affected body temperature regulation and cardiovascular response in cold environments. The importance of wearing warm hats for elderly males in winter should be emphasized.

Design for Back-up of Ship's Navigation System using UAV in Radio Frequency Interference Environment (전파간섭환경에서 UAV를 활용한 선박의 백업항법시스템 설계)

  • Park, Sul Gee;Son, Pyo-Woong
    • Journal of Advanced Navigation Technology
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    • v.23 no.4
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    • pp.289-295
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    • 2019
  • Maritime back-up navigation system in port approach requires a horizontal accuracy of 10 meters in IALA (International Association of Lighthouse Authorities) recommendations. eLoran which is a best back-up navigation system that satisfies accuracy requirement has poor navigation performance depending signal environments. Especially, noise caused by multipath and electronic devices around eLoran antenna affects navigation performance. In this paper, Ship based Navigation Back-up system using UAV on Interference is designed to satisfy horizontal accuracy requirement. To improve the eLoran signal environment, UAVs are equipped with camera, IMU sensor and eLoran antenna and receivers. This proposed system is designed to receive eLoran signal through UAV-based receiver and control UAV's position and attitude within Landmark around area. The ship-based positioning using eLoran signal, vision and attitude information received from UAV satisfy resilient and robust navigation requirements.

Thermomechanical Coupled Analysis of Carbon/phenolic Composite Structures in Reentry Environments (재진입 환경의 탄소/페놀릭 복합재 구조물의 열기계적 연계 해석)

  • Son, Myeong Jin;Shin, Eui Sup
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.47 no.6
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    • pp.414-421
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    • 2019
  • In this paper, thermomechanical coupled analysis of carbon/phenolic composites structures in reentry environment was performed. The interface of thermomechanical coupled analysis was constructed using commercial software. The governing equations of temperature and displacement fields were considered to simulate change of physical behavior due to pyrolysis and ablation effects. The results of thermomechanical coupled analysis were compared with the results of ablation test using arc-heated wind tunnel. Also, the structural stability of reentry capsule was analyzed using the analysis interface. The excellent ablation characteristics and thermal protection effects of the carbon/phenolic composites were confirmed and the constructed analysis interface can be effectively used to perform thermal protection system design.

A study on flow velocity reduction and hydrodynamic characteristics of copper alloy netting by solidity ratios and attack angles (구리합금그물감의 공극률 및 영각에 의한 유속 감소와 유체역학적 특성에 관한 연구)

  • KANG, Ahrim;LEE, Jihoon
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.55 no.1
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    • pp.62-73
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    • 2019
  • Recently, copper alloy netting has been proposed as a material for aquaculture facilities that can be set in harsh offshore environments. To design a cage made of copper alloy netting, it is necessary to calculate the flow of water through the netting and force of external sources on the netting. Therefore, this study measured and analyzed the current velocity reduction after passing through the netting and the hydrodynamic forces acting on the netting using copper alloy netting with nine solidity ratios. As a result of the reduction rate of the flow velocity through the netting, the flow reduction rate was increased as the solidity ratio of netting was increased. The flow reduction rate was also increased as the attack angle on the netting was decreased. In analyzing the resistance on the netting, we also discovered that resistance was increased with increase in the flow velocity and solidity ratio. An analysis of the hydrodynamic coefficient acting on the netting is shown that the drag coefficient tends to increase as the attack angle increases. We also analyzed the hydrodynamic coefficient according to the variation of the Reynolds number. When the drag coefficients acting on the netting were analyzed with the different Reynolds numbers, the Reynolds number increased from over 0.3 m/s to a relative constant. Finally, the copper alloy nettings had a smaller velocity reduction rate when comparing the flow velocity reduction rate between copper alloy nettings and nylon nettings.

An analysis of eye tracking experiment on the patients' viewing characteristics in dental clinic (치과 진료 시 공간 요소에 대한 환자의 주시특성파악 연구)

  • Lee, Jong-Ho;Jung, Yoona;Song, Eunsung;Ju, Kyungwon;Kim, Wonhyeon;Kim, Bongju
    • The Journal of the Korean dental association
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    • v.57 no.2
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    • pp.52-63
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    • 2019
  • Technological advances in contemporary medicine has discovered the causes of countless diseases and recorded a noticeable medical performance. As technology develops, the role of hospitals is expanding to include disease prevention of inpatients, on top of their fundamental role of treating diseases. Recently, hospitals are becoming more influential as they create environments to provide comfort and stability to patients. In this regard, contemporary hospitals are increasingly shifting their focus to create a patient-centric environment as well as develop into humanistic establishments. The same goes to dentists, as well. Since inpatients often have fear and frustration over treatment, hospitals should figure out the environmental factors that are more effective and relaxing for patients and design medical services to provide them. The patients' movement and spaces during their treatment were categorized by stages and collected for gazing information using eye tracking. It analyzed users' gaze information according to Heatmap analysis of distribution and frequency and was determined the presence or absence of stimuli on the components of space. This research is an advanced research to study and enhance treatment environment based on the analysis of patients' gazes. It attempted to create an opportunity to get closer to patient-centric environment by understanding the stimulants and obstacles and controlling the background settings.

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A Study on the Healing Environment with Architectural Spatial Composition in Healthcare Facilities - Focused on the Space Analysis of Sou Fujimoto's Healthcare Projects (의료시설 내 건축공간구성을 통한 치유환경 조성에 관한 연구 - 소우 후지모토 의료시설 사례들의 공간분석을 중심으로)

  • Jeong, Taejong
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.25 no.2
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    • pp.17-25
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    • 2019
  • Purpose: The analysis of spatial composition is required for the creation of healing environment in healthcare facilities. This study has been accomplished to provide basic data for the planning and design of hospital architecture. Methods: Literature review of healing environment and investigation on characteristics of spatial composition in healthcare facilities have been conducted. The architectural plans of four Sou Fujimoto's healthcare projects have been analyzed with space syntax. Results: The result of this research can be summarized as followed. First of all, the healing environments are consisted with architectural composition in addition to physical and psychological factors for healing environment. The second one is that the characteristics of spatial composition in Sou Fujimoto's healthcare projects are different private/public/corridor relationships in program configuration, loop or one direction circulation, combined or independent corridor with program, and radical or linear connection in spatial connection methods. The third one is that the characteristics of spatial composition in selected cases through space syntax are high variation on integration, low variation on connectivity, and high distribution in main circulation on ERAM(3). Implications: In addition to the specific spatial composition in healthcare facilities of the architect's project, it is necessary to analyze the relationship with other factors and facilities to develop the planning of hospital architecture.