• International Journal of Costume and Fashion
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• 제14권1호
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• pp.47-62
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• 2014

People today belong to many different subcultures and have diverse interests. Their job no longer defines who they are, while their pastimes can be a bigger reflection of their inner self. This article examines swing dancers in Korea, and focuses on their self-identity and how they express this through clothes. Based on in-depth interviews, observations and photographs of swing dancers with different day jobs, the study results find that most of the subjects intentionally incorporate swing dance cues in their daily work wardrobe, and that this makes them feel more comfortable, honest and satisfied with their job and identity, both as a swing dancer and working professional.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5897-5901
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• 2012

The aim of the study was to clarify the role of gastrokine 1 in the process of formation and development of gastric cancer. The expression of gastrokine 1 in gastric cancer and corresponding non-cancerous gastric tissues of 52 gastric cancer patients was assessed with the real-time fluorescence quantitative polymerase chain reaction (RT-PCR) and immunohistochemistry. We also analyzed the relationship between the expression level and clinicopathological characteristics. Gastrokine 1 gene and protein expression in gastric cancer tissues was in both cases significantly lower than in corresponding non-cancerous gastric tissues (both P<0.01), but no significant relationship was found with clinicopathological parameters including tumor location, depth of invasion, differentiation, lymph node metastasis, stage, gender, age and carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) level in peripheral blood preoperation of patients (P>0.05, respectively). Furthermore, gastrokine 1 gene expression was markedly lower in gastric cancer tissues of Helicobacter pylori (HP)-positive patients than negative ones (P<0.05). The result of the study showed that gastrokine 1 might play a significant role in the process of formation and development of gastric cancer as an anti-oncogene. Its effect might be weakened by HP infection.

• 한국실내디자인학회논문집
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• 제26권2호
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• pp.101-109
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• 2017

The food and beverage spaces of modern industrial society have transformed from a simple space for meals into a space of culture, communication and experience as society becomes more complex and diverse along side economic growth. An interior designer who is rapidly rising on this flow of change is Yukio Hashimoto. While working for interior design firm Super Potato, which highlights food and beverage spaces, he was much affected by the expression methods of representative designer Takashi Sugimoto, who makes use of natural elements. By using these expression methods that make use of natural elements in his own creation of spatial ambience and elements of experience and by adding his own differentiated expression methods, he emphasizes an effective spatial expression for food and beverage spaces. The design characteristics of Yukio Hashimoto's food and beverage spaces are as follows. First natural elements like light and water are recreated as memories of nature after being established through a methodology that allows these elements to penetrate his own thoughts. Second, he pursues a hybrid design through the harmony between past tradition and current expressive techniques. Third, he expresses objets of light through a formative sense of shape expressed with light.. Fourth, he establishes an axis in the interior space by light and structure and endows a strong directionality that induces symmetric characteristics, gaze, and movement.. Fifth, he installs lights at the bottom of weighty materials and expresses a sense of floating by light. Sixth, he uses an illusion technique that makes use of the ambiguity and depth of space resulting from reflecting materials like mirrors. The study hopes that such design expression characteristics of food and beverage spaces can be used as data for interior designers to apply and develop a new design vocabulary.

• Journal of Yeungnam Medical Science
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• 제16권1호
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• pp.43-51
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• 1999

위암환자에서 nm23 단백질이 예후인자로서의 영향을 규명하기 위해 위절제술로 얻어진 76명의 원발암 조직에 대해서 nm23 단백질의 단세포군 항체를 이용한 면역조직화학적 염색을 실시한 결과 nm23 단백질의 양성발현율은 53.9% (23/76)였다. 병리조직학적 소견들과의 비교에서 nm23 단백질의 양성발현율은 조기암보다 진행암에서, 림프절 전이 양성군에서, 그리고 암세포의 림프관 침습이 있을때 높게 나타났으며 유의한 차이가 있었다. nm23 단백질의 발현유무가 재발과 관련이 있는지에 때한 분석 결과 재발율에서 차이가 없었다. nm23 단백질 발현 유무가 생존기간에 영향을 끼치는가에 대한 단변량 분석결과 생존과 관련이 없는 것으로 나타났다. 이상의 결과로 nm23 단백질의 양성발현 여부를 예후인자로 사용하기는 어려울 것으로 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.3903-3909
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• 2016

Purpose: To evaluate the expression of Her2/neu and Ki-67 in benign and malignant gallbladder lesions, and to establish correlations with clinico-pathologic parameters. Materials and Methods: A retrospective analysis was conducted on formalin fixed paraffin embedded (FFPE) benign (n=25) and malignant gallbladder (n=25) tissue samples. Hematoxylin and eosin stained slides of each case were reviewed for: type of malignancy (whether adenocarcinoma, squamous cell carcinoma, or any other type), grade (well, moderate, and poor), depth of invasion, pre-neoplastic changes in adjacent mucosal epithelium like metaplasia and dysplasia. Immunohistochemistry for Her 2 neu and Ki-67 was performed and data analysis was conducted using SPSS 17 software. Chi-square test was used to compare categorical/dichotomous variables. P value of ${\leq}0.05$ was considered significant. Results: The difference of Her 2 neu expression and Ki67 index between benign and malignant groups was found to be statistically significant. Her2/neu positivity did not have any significant correlation with various clinicopathological parameters other than liver involvement. 5 cases of gallbladder cancer showed both Her2/neu and Ki67 positivity. Ten cases were Ki67 positive but Her2/neu negative while one case was Her2/neu positive but Ki67 negative. Conclusions: The present study demonstrated overexpression of Her2/neu and Ki67 in gallbladder cancer. A trend of decreasing Her2/neu expression with increasing grade of tumor was observed. Furthermore, greater Ki67 positivity was found in cases with lymph node metastasis and distant metastasis. Future studies with a larger number of patients will be required to precisely define the correlation of Her2/neu expression and Ki67 positivity with clinicopathological parameters. The results however are encouraging and suggest evaluation of Her2/neu as a candidate for targeted therapy.

• Asian Pacific Journal of Cancer Prevention
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• 제16권15호
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• pp.6335-6338
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• 2015

Background: Cancers have dysfunctional redox regulation resulting in production of reactive oxygen species (ROS), damaging DNA, RNA and free NTPs, and causing the accumulation of oxidative nucleic acids in cytoplasm. The major types are 8-oxo-7,8-dihydroguanine(8-oxoGsn) in RNA and 8-oxo-7,8-dihydro-2' deoxyguanosine(8-oxodGsn) in Mt-DNA. The MTH1 protein sanitizes oxidized nucleotide pools from NTPs to monophosphates, preventing the occurrence of transversion mutations. This study concerned cytoplasmic 8-oxodGsn/Gsn and MTH1 expression in gastric cancer and para-cancer tissues and elucidated roles of nucleic-acid oxidation and anti-oxidation. Materials and Methods: A polymer HRP detection system was used to detect 8-oxo-Gsn/dGsn and MTH1 expression in 51 gastric cancer and para-cancer tissue samples. Analyses of patient clinical and pathological data were also performed. Results: The expression of MTH1 and the 8-oxo-dGsn/Gsn ratio were significantly higher in cancer tissues than para-cancer tissues (P<0.05). Cytoplasmic 8-oxo-Gsn and MTH1 were both found to positively correlate (P<0.05) with tumor differentiation, while no significant associations were found with gender, age, invasion depth, lymph node metastasis and clinical stage (P>0.05). Conclusions: We found 8-oxo-dGsn/Gsn and MTH1 are both highly expressed in gastric cancer tissues, especially in well differentiated lesions. In addition, oxidated mtDNA is prevalently expressed in gastric cancers, while 8-oxo-Gsn expression in cytoplasmic RNA is a bit lower, but more selectively.

• 한국의류산업학회지
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• 제22권6호
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• pp.789-802
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• 2020

This study analyzes the experiences of a color therapy program that uses color and fashion directing to influence the psychological characteristics of adolescents, such as emotional intelligence, self-efficacy, and color expression. The subjects of this study were 15 adolescents who participated in B-City Winter School (January 6-15, 2020). Pre- and post-tests for emotional intelligence and self-efficacy were conducted to confirm the effect of the color therapy program that indicated a significant difference at the p<.05 level. Statistical significance was confirmed through the GEE model for formal characteristics used in pre/post and fashion-directed color expression. Peter pre- and post-changes in vocabulary emergence were investigated with a Word Cloud analysis using R program 4.0.2 that extracted the lower and upper categories. The significance of this study is that by expressing both color expression and fashion direction together, a program was provided for adolescents to have richer emotional experiences and career-related experiences. This study examined changes within a short period of time in 15 subjects; consequently, a follow-up in-depth qualitative analysis of the program effect and a post-testing study on maintaining the long-term effect is expected to secure further validity and usefulness of the study results. In addition, new studies are expected to contribute to the development of differentiated fashion-related education programs.

• 한국융합학회논문지
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• 제12권11호
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• pp.329-334
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• 2021

본 논문은 현대 장신구의 표현에 확대를 가져온 구성주의 특징을 살펴보고 구성주의가 장신구에 어떤 양상으로 활용되었는지 정리하였다. 구성주의의 새로운 재료에 대한 시도와 다양한 표현양식을 살펴보고 복합적인 조형의 표현 요소로 발전된 구성주의의 개념을 이해하는데 목적이 있다. 이를 위해 바우하우스에서 확장되기 시작한 구성주의의 특징을 재료와 공간 구성을 통한 표현의 양상으로 정리하였으며, 장신구 작가들의 다양한 재료의 표현 방법과 시도에 대해 분석하였다. 결과적으로 구성주의는 장신구의 조형성에 건축적 패턴의 구성, 공간의 시각화, 타 재료의 사용의 통한 입체적 표현과 심층적 개념의 조형 양상으로 확장을 보여주었으며 현대 장신구 디자인의 기초적 조형요소의 표본이 되고 있다. 하지만 구성주의의 재료적 조형요소에만 국한되어 디자인의 확장이 필요하다. 따라서 구성주의의 이념이 표현된 다양한 장신구 디자인의 확장에 대한 연구가 요구된다.

• 디지털융복합연구
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• 제15권11호
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• pp.407-412
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• 2017

영화<인셉션>을 살펴보면 인간의 꿈의 세계를 프로이드의 정신분석학 중 잠재의식이론을 적용하여 묘사하고 있음을 알 수 있는데 이러한 잠재의식의 표현을 통해 주인공의 마음 속 감정표현을 심층 있게 묘사함으로써 관객의 심도 있는 사고와 고찰이 가능한 등 인간의 본성을 통찰, 표현하는 데 새로운 관점을 제시하고 있다. 본 논문은 프로이드의 잠재의식이론을 바탕으로 영화 속의 꿈의 세계와 잠재의식의 표현에 대해 탐구하여 이를 통한 영화의 의미표현을 고찰하였다. 주인공은 그의 꿈을 통해 통제할 수 없는 잠재의식에 기인한 과거에 대한 집착과 강박관념 속에서 혼란스러운 삶을 살고 있음이 잘 묘사되고 있으며 억압된 생각과 소망이 위장된 방식으로 만족을 얻게 되는 꿈의 보충 기능을 통해서는 후회되는 순간들을 돌리기 위해 꿈을 꾸며 자위하는 모습으로 가책과 미련을 느끼고 있음이 잘 표현되고 있다. 또한 현실과 꿈속에서 갈팡질팡 하는 모습으로 의식과 잠재의식간의 충돌과 대립이 잘 표현되고 있다. 이처럼 인문학적 학문에 대한 적용 및 접목은 깊이 있는 구조의 설정과 플롯의 전개, 그리고 무엇보다도 창의적인 시공간 창출이라는 무게를 더해 줄 수 있음을 알 수 있듯이 이는 깊이 있는 대중예술 콘텐츠 제작에 대한 좋은 사례가 아닐 수 없다.

• 대한두경부종양학회지
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• 제21권1호
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• pp.3-9
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• 2005

Purpose: In oral tongue cancer, the degree of tumor invasion has a significant effect on the prognosis. We hypothesized that the destruction of extracelluar matrix and neovascularization are related to tumor infiltration mechanism. By studying the the tissues of early stage oral tongue cancer patients, we are intend to clarify the invasion related factors in oral tongue cancer. Material and Methods: To demonstrate the invasion process in early T-stage oral tongue cancer, the expressions of extracellular matrix destruction related molecules(MMP2, MMP9) and neovascularization related molecule(VEGF) were observed by immunohistochemical study. Also, immunohistochemical staining of CD31 was done for quantification of neovascularization. With the experiment showed above, we analyzed relationship between expression of each substances and tumor invasion depth, tumor free survival rates and cervical lymph node metastasis rate in early T-stage oral tongue cancer. Results: The expression rates of MMP2, MMP9, VEGF in 38 early oral cancer patients were 52.6%, 78.9% 52.6%, respectively. Significant correlation was found between the VEGF expression and microvessel density showed by CD31 immunohistochemical staining(p<0.001). VEGF expressions were significantly related with tumor invasion depth(p=0.002). The tumor free survival rate of those patients with VEGF-positive tumors was significantly poorer than in those with VEGF-negative tumors(p=0.019). Conclusion: This results indicate that VEGF is a useful marker for predicting the tumor invasion in patients with early tongue cancer and could be used as a beneficial factors in defining operative field and prognosis.