• 아동학회지
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• 제31권2호
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• pp.197-207
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• 2010

The aim of this study was to examine the effectiveness of a Laughter Therapy Group Counseling Program on overcoming anxiety, depression, and improving the self-esteem of mothers. The State-Trait Anger Scale, the Beck Depression Inventory, and the Self-Esteem Scale were used as a pre-test, post-test, and follow-up test respectively. The test results were analyzed using a t-test, a one-way analysis of variance. Twelve mothers suffering from anxiety and depression participated in eight sessions of the program, and were then compared with twelve mothers in the control group who did not receive the treatment. The treatment group showed statistically significant improvements in self-esteem, and reduced levels of anxiety and depression, in comparison to the control group. It was concluded that the program was effective in overcoming anxiety, depression, and improving self-esteem in mothers.

• 대한간호학회지
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• 제36권1호
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• pp.136-143
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• 2006

Purpose: The purpose of this study was to explore the effects of the lavender fragrance on sleep and depression in women college students, Method: Forty-two women college students who complained of insomnia were studied during a four-weekprotocol( control treatment week, $60\%$ lavender fragrance treatment week, washout week, $100\%$ lavender fragrance treatment week), All subjects were in the department of nursing in 'K' college and the study was a single blind repeated measurements experiment For the duration of the study, weekly evaluations of sleep, patterns of sleep disturbance, severity of insomnia scale, self satisfaction with sleep, and severity of depression were performed. Result: Among sleep variables, length of time taken to fall asleep, severity of insomnia, and self satisfaction with sleep were improved for the $60\%$(p=.000, p=.000, p=.000) and $100\%$(p=.000, p=.000, p=.000) week while the severity of depression was improved only for the $100\%$(p=.002)week. Conclusion: According to the study results, it can be concluded that the lavender fragrance had a beneficial effect on insomnia and depression in women college students. Repeated studies are needed to confirm effective proportions of lavender oil and carrier oil for insomnia and depression.

• 생물정신의학
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• 제15권3호
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• pp.175-185
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• 2008

Accumulating evidence has suggested the existence of reciprocal communication between immune, endocrine, and neurotransmitter system. Cytokine hypothesis of depression implies that increased pro-inflammatory cytokine such as -1, IL-6, IL-12, TNF-${\alpha}$, and IFN-${\gamma}$ in major depression, acting neuromodulators, play a key role in the mediation of behavioral, neuroendocrine, and neurochemical disturbances in depression. Concerning the relation between cytokines and serotonin metabolism, pro-inflammatory cytokines have profound effects on the metabolism of brain serotonin through the enzyme indoleamine-2,3-dioxygenase(IDO) that metabolizes tryptophan, the precursor of 5-HT to neurodegenerative quinolinate and neuroprotective kynurenate. The neurodegeneration process is reinforced by the neurotoxic effect of the hypercortisolemia during depression. From this perspective, it is possible that efficacy of antidepressants in the treatment of depression may, at least in part, rely on downregulation of pro-inflammatory cytokine synthesis. So, the use of cytokine synthesis inhibitors or cytokine antagonists may be a new treatment approach in depression. However, at present the question whether cytokines play a causal role in the onset of depression or are mere epiphenomena sustaining depressive symptoms remains to be elucidated. Nevertheless, cytokine hypothesis has created new perspectives in the study of psychological and pathophysiological mechanism that are associated with major depression, as well as the prospect for developing a new generation antidepressants.

• 생물정신의학
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• 제15권4호
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• pp.265-274
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• 2008

Depression is common in patients with end-stage renal disease(ESRD) and has a negative effect on the quality of life, functional ability, and mortality of the patients, with a prevalence rate as high as 20-25%. Especially, the increasing tendency of mortality in ESRD patients is associated with recent or current depression, and the suicide rate is also increased by depression in patients with ESRD. Therefore, accurate detection and appropriate treatment of depression is very important in ESRD patients. Also, a deferential diagnosis is needed concerning uremic symptoms and depression in ESRD patients. However, there has been little data so far particularly in terms of randomized clinical trials. This review focused on the recent knowledge of depression in ESRD, and could encourage clinical study and trials in this field.

• 대한물리치료과학회지
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• 제26권3호
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• pp.44-56
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• 2019

Despite the advances in medical technology, there are limited therapeutic interventions for cancer. Currently, the main goal of treatment is to remove a tumor completely. However, recent studies have shown that mortality is highly influenced by symptoms such as depression and cachexia, not solely by cancer itself. Depression is caused by psychological stress, and cachexia involves extreme weight loss with skeletal muscle atrophy, which are widely observed in patients with cancer. Although those two appear completely different from each other, they have a common etiology: cytokines. The production of cytokines can lead to depression and cachexia, and it contributes greatly to the increase in mortality rate. A better understanding of depression and cachexia in patients with cancer will help establish efficient treatment strategies.

• Journal of Yeungnam Medical Science
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• 제36권3호
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• pp.249-253
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• 2019

There is considerable overlap in the clinical presentations of apathy and depression. However, differential diagnosis between apathy and other psychiatric conditions, including depression and dementia, is important. In this report, we present the case of a 67-year-old woman with a history of receiving selective serotonin reuptake inhibitor (SSRI) treatment for depression. Differential diagnosis between treatment-resistant depression and SSRI-induced apathy syndrome was required. The symptoms of her apathy syndrome were relieved after the discontinuation of SSRIs and the addition of olanzapine, methylphenidate, and modafinil. Furthermore, we briefly review related literature in this article.

• 대한한방내과학회지
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• 제41권6호
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• pp.1300-1306
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• 2020

Background: The aim of this study was to determine the clinical effects of complex Korean medicine therapy for tinnitus associated with ear fullness, depression, and anxiety. Case Report: A 52-year-old female patient suffering from tinnitus with ear fullness, depression, and anxiety was treated with acupuncture, pharmacopuncture, and herbal medicine. We used the Tinnitus Handicap Inventory (THI), Beck Depression Inventory (BDI-II), Beck Anxiety Inventory (BAI), and a Verbal Numerical Rating Score (VNRS) to assess the patient's symptoms. The administration of the acupuncture, pharmacopuncture, and herbal medicine improved the ear fullness, depression and anxiety symptoms. No side effects were observed during the treatment. Conclusion: The study findings suggest that complex Korean medicine therapy, such as acupuncture, pharmacopuncture, and herbal medicine, may be effective for the treatment of tinnitus associated with ear fullness, depression, and anxiety.

• 보건행정학회지
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• 제34권1호
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• pp.68-77
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• 2024

연구배경: 우울은 저하된 기분이 비교적 경미한 수준인 일상 우울과 병적 상태인 임상적 우울로 구분할 수 있다. 우울 경험은 치료순응도 저하, 신체증상 등을 경험하게 하여 의료이용을 높일 수 있으나 우울 중 임상적 우울 집단은 질환에 대한 사회적 편견을 경험하여 의료이용이 제한될 수 있다. 의료이용은 개인 나아가 사회 문제의 원인이 되어 중요하다는 측면에서 본 연구는 임상적 우울 집단, 일상 우울, 비우울 집단의 의료이용을 비교하여 살펴보고자 한다. 방법: 일반화 성향점수(generalized propensity score) 기반 처치역확률가중기법(inverse probability of treatment weighting)을 이용하여 비우울, 일상 우울, 임상적 우울 집단 간 공변량의 불균형을 최소화하고 우울과 의료이용, 총진료비의 관계를 각각 음이항 회귀분석과 로그변환한 선형회귀분석을 통해 확인하였다. 결과: 우울은 여성, 소득이 낮은 집단, 교육수준이 낮거나 배우자가 없거나 건강보험에 가입되지 않았거나 경제활동을 하지 않은 집단에서 높았으며, 우울중 임상적 우울은 경제활동을 하지 않거나 민간의료보험에 미가입된 집단, 질환의 보유개수가 많은 집단에서 비중이 높았다. 의료이용 횟수는 우울 집단(일상 우울 집단 및 임상적 우울 집단)이 비우울 집단보다 유의하게 높았으며, 임상적 우울 집단이 일상 우울 집단보다 유의하게 높았다. 총진료비는 우울 집단이 비우울 집단보다 높았으나, 임상적 우울 집단과 일상 우울 집단 간에는 유의한 차이가 없었다. 결론: 의료이용은 비우울 집단보다 우울 집단(임상적 우울 집단 과 일상 우울 집단)에서 높았으며, 임상적 우울 집단보다 일상 우울 집단에서 높았다.

• 대한불안의학회지
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• 제6권1호
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• pp.55-64
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• 2010

Objective : Depression is a significant and growing problem among college students. Depression contributes to numerous academic, social, and health problems, including suicide. This study surveyed depression awareness and the need for establishing a depression support program through Kyunghee University. Methods : We used the Kyunghee University Mail delivery system for college students to conduct this survey on depression and depression. Results : All of the students who responded to the survey, 41.86% reported that they had experienced depression. Among students experiencing depression, 27.27% experienced suicidal ideation, and 56.56% said they wanted to receive mental health counseling or treatment. All the respondents, 47.04% of respondents said they would to go to the external medical center, not school's internal counseling center of school, for such treatment. All the respondents, 73.75% said the student depression/suicide problem was serious. In addition, 71.34% of respondents required a depression support program. Conclusion : The university's depression support program needs to improve its accessibility by developing content focused on the early detection of, and improved awareness of, depression.

• 여성건강간호학회지
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• 제20권2호
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• pp.163-172
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• 2014

Purpose: The purpose of this study was to determine the stress, depression, and fetal attachment of pregnant women who underwent infertility treatment, and to identify factors associated with fetal attachment. Methods: As a correlation survey design, data were collected from 136 pregnant women who underwent infertility treatment. Data were analyzed using ${\chi}^2$-test, t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression. Results: Stress, depression, and fetal attachment averaged $3.01{\pm}0.60$ (range of scale 1~5), $10.02{\pm}6.51$ (out of a possible 63), and $3.64{\pm}0.55$ (range of scale 1~5), respectively. Level of fetal attachment was higher when mother's age was less than 35, having other children, and having prenatal education experience. Lower score of depression and client's age less than 35 were significant factors affecting fetal attachment. Conclusion: Infertility is a life-affecting trauma for the individual, and personal and social changes due to infertility cause physical and psychological difficulties even after a successful pregnancy with infertility treatment. Therefore, prenatal management programs need to be developed giving consideration to the emotional and physical changes in order to promote physical and psychological stability in the women pregnant following infertility treatment.