• 생물정신의학
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• 제8권1호
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• pp.47-52
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• 2001

It is known that the personality is the crucial factor in the treatment outcome of depression. The authors tried to identify the results of such studies and various components which determine the treatment outcome of depression. Nearly 60 papers published between the year 1990 and 2000 about the treatment of depression and personality were reviewed. Among them about 30 papers were selected to compare the research methods, results and discussions. The arguments and critics of the papers were discussed. In the many debates, the authors admitted the fact that premorbid personality trait influences the treatment outcome of depression negatively regardless of treatment method. Subtyping of depression is feasible along the presence of good or bad predictors of treatment outcome for depression. Differentiation of depression and personality seems to have no problem, however test of personality state before the development of psychiatric disorder such as depression is not amenable. For example, cluster A personality trait is often misunderstood as depression in clinical setting. In some cases cognitive behavioral therapy is effective in the treatment of depression accompanying personality disorder. The authors insist that the analysis of personality in the dimensional aspect rather than in the categorical aspect gives more information in the research of personality influencing the treatment outcome of depression. In addition, the reason why we understand the relationship between depression and personality were discussed.

• 대한한의학회지
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• 제42권4호
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• pp.208-221
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• 2021

Objectives: The purpose of this article was to investigate the current status of clinical studies of acupuncture treatment for depression using neuroimaging method, focusing on SCI papers. Methods: We searched for clinical trial studies of acupuncture treatment for depression using neuroimaging method in the MEDLINE (Pubmed), OASIS, and RISS database. Once the online search was finished, studies were selected manually by the inclusion criteria. Finally, we analyzed the characteristics of selected articles and reviewed the neural substrates of acupuncture treatment in depression. Results: Total eight studies were included in this study. The most frequently utilized modality was functional MRI. The most frequently selected acupoint for depression was GV20. Several studies revealed that acupuncture treatment could improve the symptoms of depression. In this manuscript, we demonstrated that neuroimaging techniques could capture the neural substrates associated with depression and acupuncture treatment may modulate the activation of brain areas which were impaired in depression in a different way from sham acupuncture. Conclusions: Utilizing neuroimaging methods to explore neural mechanism of acupuncture treatment on depression would be helpful in clinical trials and more efforts should be needed in this fields.

• Korean Journal of Acupuncture
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• 제33권2호
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• pp.84-88
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• 2016

Objectives : To assess and compare the effectiveness of acupuncture treatment of depression in epilepsy children and adolescent's parents. Methods : 20 cases of depression in epilepsy children and adolescent's parents were investigated in Southern TCM Centre, Southern University College, Malaysia. Subjects were randomly divided into two groups; Acupuncture treatment group and Herbal medication treatment group. Family relationships questionnaires and Hamilton Depression Rating Scale were used before, after 4 weeks and 8 weeks treatments in order to investigate the effectiveness of treatment. Results : After 4 weeks Acupuncture treatment group showed significant reduction in the Hamilton Depression Rating Scale. On the other hand, after 8 weeks both groups showed significant reduction in Hamilton Depression Rating Scale. Conclusions : The result suggests that the effectiveness of Acupuncture treatment is comparable with treat of Herbal medication treatment to reduce parent's Hamilton Depression Rating Scale.

• 동의신경정신과학회지
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• 제25권4호
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• pp.311-318
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• 2014

Objectives: As the elderly population grows and the prevalence of depression increases, the incidence of geriatric depression disorder will continue to increase. The effect of an intensive Korean medicine treatment program on geriatric depression disorder was studied. Methods: Geriatric depression disorder patients who received treatment over a period of three years were reviewed, with the geriatric depression score (GDS) used as the primary outcome. The intensive Korean medical treatment program applied to the geriatric depression disorder patients consisted of herbal medicine, acupuncture, pharmacopuncture, moxibustion, meditation, qigong exercises, and reminiscence therapy. Results: The GDS scores of patients who received the intensive Korean medical treatment program decreased from an average of 19.57 (${\pm}5.52$) to 15.76 (${\pm}6.99$) and there was a significant difference. Conclusions: When the intensive Korean medical treatment program was applied to geriatric depression disorder patients, the symptoms of depression improved. This treatment program will be helpful for improving symptoms in patients and can be applied by trained clinicians.

• 생물정신의학
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• 제14권1호
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• pp.21-27
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• 2007

Objectives : As a part of plan to develop evidence-based treatment guidelines for depression that is more suitable for Korean situation, we investigate the present status and client's requirements for non-pharmacological treatment of depression in Korean clinical situation. Methods : Subjects were patients with depression in 12 university hospitals which are located in metropolises in Korea. We analyzed the records from questionnaires about current clinical status and requirements for the non-pharmacological treatment of depression in Korea. Results : 50.8% of the subjects have experienced non-pharmacological treatments for their depression. The preference of non-pharmacological treatment method of depression is exercise/interesting activity, counseling by psychiatrists and psychotherapy, and the best effective treatment method is psychotherapy (Es=4.36). Actually, the mean consultation time by psychiatrist is $11.31{\pm}7.16$ min, and the appropriate consultation time for client's situation is $18.39{\pm}8.95$ min. During consultation, patients' satisfaction measurement for psychiatrist's explanation about pharmacological treatment is $64.17{\pm}27.11$, and satisfaction measurement for psychiatrist's counseling for their depression about personal problems, resent stress, interpersonal relationship is $61.66{\pm}26.63$. Conclusion : In Korea, many psychiatrists offered biologically oriented treatment to their patients with depression, and patients' satisfaction measurement about consultation by psychiatrists is low. Many patients wanted to combined pharmacological and non-pharmacological treatment for their depression, and aspired to information about complementary and self-help treatment methods. It is necessary to develop non-pharmacological treatment guideline for depression which reflect the clinical situation in Korea and meet Korean patients' need.

• 신경정신의학
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• 제57권4호
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• pp.287-300
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• 2018

Of the different phases of bipolar disorder, bipolar depression is more prevailing and is more difficult to treat. However, there is a deficit in systemic research on the pharmacological treatment of acute bipolar depression. Therefore, consensuses on the pharmacological treatment strategies of acute bipolar depression has yet to be made. Currently, there are only three drugs approved by the Food and Drug Administration for acute bipolar depression : quetiapine, olanzapine-fluoxetine complex, and lurasidone. In clinical practice, other drugs such as mood stabilizers (lamotrigine, lithium, valproate) and/or the other atypical antipsychotics (aripiprazole, risperidone, ziprasidone) are frequently prescribed. There remains controversy on the use of antidepressants in bipolar depression. Here, we summarized the evidence of current pharmacological treatment options and reviewed treatment guidelines of acute bipolar depression from recently published studies.

• 생물정신의학
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• 제8권1호
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• pp.37-46
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• 2001

Whenever a clinician manages the patients with depression, he may meet various problems that make it difficult to treat them. Even though he has good skills and knowledge about depression, some barriers will be appear during his practice. In general, the difficulties in treating depression are treatment-resistance, adverse effects of antidepressants, pregnancy in female patients, comorbid medical conditions, poor compliance, drug-drug interactions, and so on, which are related with pharmacological treatments. Here, only the two of them, the treatment-resistant depression and difficult problems concerned with pregnancy, were discussed. Some level of treatment resistance is the norm rather than the exception. As the treatment failure stems from inadequate treatment, it is important that the clinician should prescribe medications with sufficient doseage and adequate duration. And to overcome the treatment resistant depression the polypharmacy is necessary, in that case, the side effects and toxicities should be explored and managed immediately. So the clinician have to learn more about the pharmacokinetic and pharmacodynamic mechanisms of each drugs used in treatment of depression. When the risk of the fetus by the exposure is higher than the risk of untreated maternal psychiatric disorder, psychotropic medications should be used during pregnancy. Women who are maintained on psychotropics and become pregnant, as well as women with the new onset of psychiatric symptoms during pregnancy, should be carefully reassessed. However, data concerning the potential risk of long-term behavioral changes following prenatal exposure to psychotropics is rare, so further longitudinal follow-up studies are needed.

• 생물정신의학
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• 제12권2호
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• pp.89-97
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• 2005

Depression is a frequently developed psychiatric symptom after stroke. Poststroke depression(PSD) causes not only psychological distress related to depression but also other disturbances in many areas such as cognitive function, activities of daily living and quality of life. Therefore, a comprehensive understanding of accurate detection and appropriate treatment of depression is mandatory in patients with stroke. This review focused on the current knowledge of PSD.

• 한국치위생학회지
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• 제15권5호
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• pp.777-786
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• 2015

Objectives: The purpose of the study was to investigate the influencing factors on anxiety and depression before and after prosthetic treatment in the patients. Methods: A self-reported questionnaire was completed by 248 patients with tooth loss and over 20 years old. The questionnaire was carried out before and after oral examination and dental prosthetic treatment from July to December, 2013. The study instruments included Beck's anxiety inventory and self-rating depression scale by Zung. The questionnaire was adapted and modified from Kwon's anxiety inventory and Lee's depression scale. Results: While the anxiety level increased from 69.4% to 78.2% in the normal people, the depression level changed from 53.2% to 64.1% in the normal people. The gender variable had a positive effect on anxiety and depression while educational level had a negative effect on them. The dental fear was closely related to anxiety and depression before and after the prosthetic treatment. The entire body health perception showed a negative effect on anxiety and depression. The distrust towards the dentist had an influence on the anxiety and depression in the prosthetic patients. Conclusions: The influencing factors on anxiety and depression in the prosthetic patients included gender, dental fear, entire body perception, and distrust towards the dentist.

• 동의신경정신과학회지
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• 제21권4호
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• pp.187-206
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• 2010

Objectives : This study was designed to report the effect of korean traditional treatment and person-centered counseling for poststroke depression Methods : We treated two patients who scored 37 point and 32 point at Beck's depression inventory each, and 23 point and 22 point at Hamilton rating scale for depression each by korean traditional treatment and person-centered counseling, Results : After treatment, the clinical symptoms were improved and Beck's depression inventory, Hamilton rating scale for depression score were decreased, Conclusions : The result suggest that korean traditional treatment and person-centered counseling is effective in patients with poststroke depression.