• Journal of Oriental Neuropsychiatry
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• v.31 no.4
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• pp.269-278
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• 2020

Objectives: Yukmijihwang-won (Liuweidihuang-wan in Chinese) is a frequently used medicinal herbal formula. It is used as Yin tonic in Korea and China to recover patients from Yin deficiency. However, the scientific evidence on this drug has not revealed the beneficial effect or mechanism of its effects on the neurological disorder. We designed this study to examine the antidepressive and analgesic effects of Yukmijihwang-won (YJ-01) and the minor modification of YJ-01, YJ-06 on the reserpine-induced pain-depression dyad mice model. Methods: Reserpine (1 mg/kg) was administered subcutaneously once a day for three consecutive days to induce pain and depression-like behavior. The oral administration of YJ-01 and YJ-06 (100, 200, or 300 mg/kg) was performed once daily from three days after the reserpine injection. Results: Repeated administration of the YJs significantly reduced the immobility time in a forced swimming test and increased the moved distance and number of crossings in the open field test. In the von-Frey filament test, the oral administration of YJs remarkably suppressed the increase in paw withdrawal frequency. Conclusions: The results of this study suggest that YJ-01 and 06 may be good candidates to treat the pain-depression dyad.

• Journal of the Korea Fashion and Costume Design Association
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• v.18 no.1
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• pp.1-10
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• 2016

The purpose of this study was to examine the influence of elderly women's makeup behavior, psychological traits and demographic variables on their preference for makeup images in daily life(hereinafter called general makeup image) and for the makeup images of their own future funeral portraits. As for the method of research, a research study was implemented by using the questionnaire method. Seven factors were selected for makeup behavior: fashionability, conformity, subjectivity, instrumentality, interpersonal orientation and conspicuousness. The selected psychological traits were personality, death attitude and depression. Preference for general makeup image and for the makeup image of funeral portrait were investigated in terms of four: agreeableness, refinement, individuality and dignity. The subjects in this study were 651 female elderly residents in and around Seoul who were in their 60s to 80s. Concerning data analysis, factor analysis, Cronbach alpha coefficient, Pearson productmoment correlation coefficient, t-test, one-way ANOVA, Duncan's multiple range test and multiple regression analysis were utilized. Concerning the influence of the elderly women's makeup behavior, personality, death attitude, depression and demographic variables on preference for the makeup image of funeral portrait, their preference for an agreeable makeup image was analyzed. Thus, makeup behavior, personality, death attitude and depression were identified as the variables to exert a significant influence on preference for the makeup images of funeral portrait. The findings of the study are expected to help make makeup for funeral portrait entrenched as a part of the beauty industry and to make a contribution to the development of the beauty industry.

• Biomolecules & Therapeutics
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• v.22 no.5
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• pp.453-459
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• 2014

Chronic mild stress (CMS) has been reported to induce an anhedonic-like state in mice that resembles some of the symptoms of human depression. In the present study, we used a chronic mild stress animal model of depression and anxiety to examine the responses of two strains of mice that have different behavioral responsiveness. An outbred ICR and an inbred C57BL/6 strain of mice were selected because they are widely used strains in behavioral tests. The results showed that the inbred C57BL/6 and outbred ICR mice were similarly responsive to CMS treatment in sucrose intake test (SIT) and open field test (OFT). However, the two strains showed quite different responses in forced swimming test (FST) and novelty-suppressed feeding (NSF) test after 3 weeks of CMS treatment. Only C57BL/6 mice displayed the depression- and anxiety-like behavioral effects in response to CMS treatment in FST and NSF test. Our results suggest that there are differences in responsiveness to CMS according to the different types of strain of mice and behavioral tests. Therefore, these results provide useful information for the selection of appropriate behavioral methods to test depression- and anxiety-like behaviors using CMS in ICR and C57BL/6 mice.

• Journal of Korean Academy of Nursing Administration
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• v.16 no.1
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• pp.26-36
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• 2010

Purpose: The purpose of this study was to investigate the relationships among psycho-social well-being, and health perception and behavior in clinical nurses. Methods: The data were collected from 362 nurses employed at five general hospitals. A self-reported questionnaire was used to assess demographics and job characteristics, health perception and behavior, depression, and psycho-social stress. The data were analysed using Cronbach's alpha, descriptive statistics, t-test, and ANOVA. Results: While nurses perceived themselves to be in good health, represented by a high mean for health perceptions, actual health behavior was poor as the mean for health behavior was low. Forty two percents of the subjects were categorized as having major depression and high-stress levels. There were statistically significant differences in psycho-social well-being according to age, marital status, years of employment, and monthly salary. Also, there were significant differences in psycho-social well-being according to health perception, regular meals and exercise, sufficient sleep, job related injury and accident, and absences for ill. Conclusion: In order to prevent depression and improve psycho-social well-being among clinical nurses, organizational support and health management needs to be focused on high-risk nurses. Furthermore, it is essential to consider the health perception and behavior of clinical nurses.

• Korean Journal of Adult Nursing
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• v.25 no.5
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• pp.549-558
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• 2013

Purpose: The purpose of this study was to identify impact of stress on depression among university students and the moderating effect of social support in the relationship between stress and depression in university students. Methods: A total of 445 subjects were participated from May to July 2011. Data were collected by self-reported questionnaires and t-test, ANOVA, and stepwise multiple regression with SPSS/WIN 20.0 were used to analyze the data. Results: The results indicate that depression was increased by stress and decreased with social support. Social support included four type of social support behavior; emotional support, informational support, material support, and appraisal support. Multiple regression analysis showed that moderating effect of emotional support was significant when provided by friends but not by parents. Conclusion: These finding indicate the importance of emotional support of friends on depression in university students.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.129-136
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• 2019

This study was conducted to identify the health promotion behavior of patients with pulmonary tuberculosis and examine the factors influencing this behavior. The subjects were 152 outpatients who were treated for pulmonary tuberculosis at the national tuberculosis hospital located in M City. Data were collected from July to September, 2016 and analyzed using the t-test, ANOVA, Duncan's test, Pearson's correlation coefficient, and multiple regression analysis. Health promotion behavior was negatively correlated with physical symptoms, perceived barriers, and depression, but positively correlated with self-efficacy. The most powerful variable influencing health promotion behavior was depression and the model showed an explanatory power of 63.5%. The results of this study suggest that it is necessary to employ a variety of strategies to practice and maintain the health promotion behavior of pulmonary tuberculosis patients to decrease their depression and provide psychological support.

• The Korea Journal of Herbology
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• v.29 no.2
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• pp.7-13
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• 2014

Objectives : Chronic mild stress (CMS) model is currently recognized as a better animal model of depression. The purpose of this study was to investigate the antidepressant-like effects of the Nelumbo nucifera leave extract using CMS model. Methods : The antidepressant-like effects of Nelumbo nucifera leaves extract was determined by using animal models of depression. Male ICR mice were divided into four groups: saline-treated normal, without CMS; saline-treated stress control; CMS+ Imipramine(20mg/kg); CMS+Nelumbo nucifera leaves extract(200mg/kg). All mice except the normal group exposed an unpredicted sequence of chronic mild stressors for 5 weeks. The behavior of mice were detected by sucrose preference test, forced swim test and tail suspension test. Then concentration of corticosterone in serum was detected by enzyme immunoassay. Results : Nelumbo nucifera leaves extract administration by daily gavage from the 3rd week exhibited an antidepressant-like effect on CMS-induced depression in mice. Nelumbo nucifera leaves extract administration at dose of 200 mg/kg significantly increased the sucrose consumption, and decreased the immobility durations in forced swim test and tail suspension test. Furthermore the corticosterone level decreased than control group. Conclusions : Chronic mild stress can affect mouse behavior and corticosterone level and cause depression. The present experiments not only further confirm the antidepressant-like effects of Nelumbo nucifera leaves extract in the sucrose preference test, forced swimming test and tail suspension test, but also the improving effects of Nelumbo nucifera leaves extract on the depression-like symptoms in the CMS model. Nelumbo nucifera leaves extract has the antagonism on CMS and produce antidepressive effects.

• Journal of Korean Biological Nursing Science
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• v.20 no.2
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• pp.84-91
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• 2018

Purpose: The purpose of this study was to construct and test a structural equation model to investigate the risk factors of metabolic syndrome in rural women. Methods: The raw data in this study was collected from the Korean Genome and Epidemiology Study supervised by the Korea Centers for Disease Control and Prevention from 2005 to 2010. The data included physical examinations and surveys of 1,125 women, who resided in three rural areas of South Korea. The structural model in this study was composed of five latent variables: depression, stress, social support, health behavior, and metabolic syndrome. The structural equation model was used to assess the relationships among the variables. Results: The results of the study showed that depression and stress had direct effects on metabolic syndrome. Social support had a direct effect on health behavior and metabolic syndrome. Also, health behavior had a direct effect on metabolic syndrome. Conclusion: This study may serve as a guideline for interventions and strategies used to reduce metabolic syndrome in rural women.

• Research in Community and Public Health Nursing
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• v.9 no.1
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• pp.104-116
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• 1998

The paper was studied those aged of 65 years or over who were attending 11 senior citizen's centers and 4 nursing home centers for the aged during the day in Junla-buk do. The purpose of this study was to measure the level of depression and related factors by using the 20 part Zung's self-rating interview schedule. The results of the study were analized using an SAS program. Data analysis included the following : percent, average, S.D, ANOVA, T-test, Person's simple correlation, multiple regression. The results of the study are as follows: 1. The mean value of depression was 45.54 out of a total of 80 and the mean depression scale was 2.28 on a Likert scale. Those over a 50 degree depression rate was 37.7%. 2. There was a significant decrease of depression when monthly pocket money increased. 3. There was a significant decrease in depression degree when they think their health is good and they have no chronic disease. 4. There was a significant decrease in depression degree when activities of daily living increased, r= -0.537 and p=0.0001. There was a significant decrease in depression degree when health promoting behavior increased, r= -0.752 and p=0.0001. 5. There was a significant decrease in depression degree when social activities increased, in meeting a relatives and attending a senior citizen's center.

• The Journal of Korean Academic Society of Nursing Education
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• v.16 no.1
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• pp.14-23
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• 2010

Purpose: The purpose of this study was to investigate the relationship among stress, depression, coping styles and satisfaction of clinical practice in nursing students. Method: Two hundred fifty-eight nursing college students in 1 city were selected by convenient sample. A questionnaire measured the level of stress, depression, coping styles and satisfaction of clinical practice. The data were analyzed using descriptive statistics, t-test, ANOVA, and Pearson's correlation coefficient. Result: The mean score of stress was 2.82 (${\pm}.39$), depression was 19.23 (${\pm}7.70$), coping styles was 2.42 (${\pm}.42$), and satisfaction of clinical practice was 2.81 (${\pm}.41$). There were significant differences on four variables according to the satisfaction of a nursing major. Stress had a significant positive correlation with depression, and a negative correlation with problem focused coping and satisfaction of clinical practice. Depression had a significant negative correlation with satisfaction of clinical practice. Emotional focused coping had a significant positive correlation with depression, and problem focused coping had a significant negative correlation with depression. Conclusion: From the studies reviewed, one can expect a positive effect on decreasing stress and depression among nursing students when the nursing educators use counseling and instruction for clinical practice.