• Title/Summary/Keyword: Department of nuclear medicine

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Extracardiac Uptake of Thallium-201 during Myocardial Perfusion Imaging with Pharmaeologic Vasodilation (심근관류 스캔중에 나타난 Thallium-201의 심장외 국소적 섭취)

  • Choi, Chung-Il;Kwak, Dong-Suk;Chung, Byung-Cheon;Park, Moo-Keun;Lee, Jae-Tae;Lee, Kyu-Bo
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.1
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    • pp.65-71
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    • 1992
  • Myocardial perfusion imaging with $^{201}Tl-chloride$ following exercise or vasodilator-induced hyperemia has been effective in detecting the presence of coronary artery disease. An increased lung uptake of thallium has been reported as a sensitive marker of severe and extensive coronary artery disease and associated with poor prognosis. Thallium has also been noted to concentrate in a variety of malignant lesions. We report 5 cases of extracardiac uptake of thallium during myocardial perfusion scan with pharmacologic vasodilation. Accumulation of thallium was found in the lesions of a breast cancer, a lung cancer, a Castleman's disease and 2 cases of thymoma. We believe that the presence of focal extracardiac uptake of thallium during myocardial perfusion scan should suggest the need for further clinical evaluation to detect the tumor and must differentiate the increased lung uptake of thallium due to left ventricular dysfunction in coronary artery disease.

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Gastric Emptying Time (GET) Test Using Radioisotope (방사성동위원소를 이용한 Gastric Emptying Time의 연구)

  • Koo, Bon-Hwan;Ha, Sung-Woo;Son, Sang-Kyun;Lee, Jae-Tae;Lee, Kyu-Bo;Whang, Kee-Suk
    • The Korean Journal of Nuclear Medicine
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    • v.22 no.2
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    • pp.187-192
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    • 1988
  • A gamma camera coupled to a computer was used in 20 normal volunteers after ingestion of the mixture of $^{99m}Tc-DTPA$ and milk in order to determine gastric emptyng time (GET) and to evaluate the effect of metoclopramide, a dopamine antagonist that stimulates gastric motility, to gastric emptying. The normal value for biological gastric emptying half time was found to be $63{\pm}7$ minutes, and the gastric emptying was monoexponential fashion, at least for the first 60 minutes. Among the 20 volunteers, nine were repeated the test after injection of metoclopramide, which has significantly reduced the value of GET to $31{\pm}3$ minutes (p<0.01). GET test using $^{99m}Tc-DTPA$ is very useful in gastric function evaluation, especially in follow-up check of the functional change.

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Beta-Adrenergic Receptor Imaging

  • Inubushi, Masayuki;Tsukamoto, Tekahiro;Naya, Masanao;Morita, Koichi;Tamaki, Nagara
    • 대한핵의학회:학술대회논문집
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    • 2006.05a
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    • pp.27-27
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    • 2006
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Preparation of $^{82}Sr/^{82}Rb$ Generator and Positron Emission Tomographic Image of Normal Volunteer ($^{82}Sr/^{82}Rb$ 발생기의 제조 및 정상인 심근의 양전자 단층촬영상)

  • Jeong, Jae-Min;Chung, June-Key;Lee, Dong-Soo;Kwark, Cheol-Eun;Lee, Kyung-Han;Lee, Myung-Chul;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.326-330
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    • 1994
  • A $^{82}Sr/^{82}Rb$ generator was prepared by loading $^{82}Sr$ to preconditioned tin dioxide column. The generator was eluted by normal saline with flow rate up to 8m1/min, and the eluted radioactivity was monitored by dose calibrator. Radioactivity began to come out at 5ml and reached to peak around 9ml. The total eluted radioactivity increased linearly with flow rate, and the maximum obtained radioactivity was 35mCi at 8m1/min. The $^{82}Rb$ preparation was proven to be free from both strontium radioactivity and pyrogen. The $^{82}Rb$ was injected to normal female volunteer and positron emission tomographic Image of heart was obtained successfully.

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