• 제목/요약/키워드: Department of Radiological Science

검색결과 2,510건 처리시간 0.028초

A Numerical Study of Different Types of Collimators for a High-Resolution Preclinical CdTe Pixelated Semiconductor SPECT System

  • Jeong, Hyun-Woo;Kim, Jong Seok;Bae, Se Young;Seo, Kanghyen;Kim, Seung Hun;Kang, Seong Hyeon;Shin, Dong Jin;Lee, Chang-Lae;Kim, Kyuseok;Lee, Youngjin
    • Journal of the Optical Society of Korea
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    • 제20권6호
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    • pp.663-668
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    • 2016
  • In single-photon-emission computed tomography (SPECT) with a pixelated semiconductor detector (PSD), not only pinhole collimators but also parallel-hole collimators are often used in preclinical nuclear-medicine imaging systems. The purpose of this study was to evaluate and compare pinhole and parallel-hole collimators in a PSD. For that purpose, we paired a PID 350 (Ajat Oy Ltd., Finland) CdTe PSD with each of the four collimators most frequently used in preclinical nuclear medicine: (1) a pinhole collimator, and (2) low-energy high-resolution (LEHR), (3) low-energy general-purpose (LEGP), and (4) low-energy high-sensitivity (LEHS) parallel-hole collimators. The sensitivity and spatial resolution of each collimator was evaluated using a point source and a hot-rod phantom. The highest sensitivity was achieved using LEHS, followed by LEGP, LEHR, and pinhole. Also, at a source-to-collimator distance of 2 cm, the spatial resolution was 1.63, 2.05, 2.79, and 3.45 mm using pinhole, LEHR, LEGP, and LEHS, respectively. The reconstructed hot-rod phantom images showed that the pinhole collimator and the LEHR parallel-hole collimator give a fine spatial resolution for preclinical SPECT with PSD. In conclusion, we successfully compared different types of collimators for a preclinical pixelated semiconductor SPECT system.

담배연기와 담뱃잎 내 함유된 방사능 농도분석 및 위해도 평가 (Analysis of Radioactivity Concentrations in Cigarette Smoke and Tobacco Risk Assessment)

  • 이세령;이상복;김정윤;김지민;방예진;이두석;조형준;김성철
    • 대한방사선기술학회지:방사선기술과학
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    • 제44권5호
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    • pp.489-494
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    • 2021
  • In this study, radioactivity quantitative analysis was performed on radon contained in cigarette, and the effective dose was calculated using the result value to determine the amount of exposure caused by smoking. A total of 5 types of cigarettes were sampled. Cigarette smoke was collected by using activated carbon, and tobacco were measured by homogenizing for quantitative analysis. For each sample, Bi-214 and Pb-214 were subjected to gamma nuclide analysis to observe the uranium-based radioactive material contained in cigarette, and a measurement time of 30,000 seconds was set for the sample based on the results of previous studies. As a result of measuring the radioactivity of tobacco, a maximum of 0.715 Bq/kg was derived, and in the case of cigarette smoke measured using activated carbon, a maximum of 3.652 Bq/kg was derived. Using this measurement, the average effective dose to the lungs is 0.938 mSv/y, and it was found that there is a possibility of receiving exposure up to 1.099 mSv/y depending on the type of tobacco. It was found that the exposure dose due to cigarette occupies a large proportion of the annual effective dose limit for the general public. Therefore, more diverse studies on radioactive substances in cigarette are needed, and measures to monitor and reduce the incidental exposure to radon should be established.

노이즈 레벨 및 유사도 평가 기반 저선량 조건의 전산화 단층 검사 영상에서의 비지역적 평균 알고리즘의 최적화 (Optimization of Non-Local Means Algorithm in Low-Dose Computed Tomographic Image Based on Noise Level and Similarity Evaluations)

  • 정하선;김이준;박수빈;박수연;오윤지;이우석;서강현;이영진
    • 대한방사선기술학회지:방사선기술과학
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    • 제47권1호
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    • pp.39-48
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    • 2024
  • In this study, we optimized the FNLM algorithm through a simulation study and applied it to a phantom scanned by low-dose CT to evaluate whether the FNLM algorithm can be used to obtain improved image quality images. We optimized the FNLM algorithm with MASH phantom and FASH phantom, which the algorithm was applied with MATLAB, increasing the smoothing factor from 0.01 to 0.05 with increments of 0.001 and measuring COV, RMSE, and PSNR values of the phantoms. For both phantom, COV and RMSE decreased, and PSNR increased as the smoothing factor increased. Based on the above results, we optimized a smoothing factor value of 0.043 for the FNLM algorithm. Then we applied the optimized FNLM algorithm to low dose lung CT and lung CT under normal conditions. In both images, the COV decreased by 55.33 times and 5.08 times respectively, and we confirmed that the quality of the image of low dose CT applying the optimized FNLM algorithm was 5.08 times better than the image of lung CT under normal conditions. In conclusion, we found that the smoothing factor of 0.043 among the factors of the FNLM algorithm showed the best results and validated the performance by reducing the noise in the low-quality CT images due to low dose with the optimized FNLM algorithm.

CT 영상에서 뇌출혈의 자동인식 (Intracerebral Hemorrhage Auto Recognition in Computed Tomography Images)

  • 최석윤;강세식;김창수;김정훈;김동현;예수영;고성진
    • 대한방사선기술학회지:방사선기술과학
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    • 제36권2호
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    • pp.141-148
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    • 2013
  • CT 검사 시 뇌출혈의 부위는 심각한 정도에 따라 인지하기 어려운 경우도 있으며, 응급상황에서 숙련이 되지 않은 의료진에게는 부담을 준다. 응급상황에서 검사와 동시에 뇌출혈부위를 자동으로 빨리 파악하고 정량적인 정보를 제공하는 보조적인 역할은 필요하며, 컴퓨터를 이용한 자동 검출 및 인식 시스템은 출혈부위 진단에 매우 큰 도움을 줄 수 있다. 본 연구에서는 출혈부위를 문턱치값 처리, 모폴로지 연산, 원형률 계산을 접목하여 뇌 출혈부위의 자동검출에 성공하였고 검출 후보군에서 잘 못 선정된 영역을 판정하기위한 주성분분석을 이용한 분류기 개발에 성공하였다. 개발된 시스템을 응급상황의 뇌출혈 환자에게 적용한다면 의료진에게 수술계획을 위한 유용한 정보가 될 것으로 사료된다.

소아 X선 촬영조건 변화에 따른 소아 및 촬영보조자 선량 (Doses of Pediatric and X-ray Examination Assistants according to Changes in Pediatric X-ray Exposure Conditions)

  • 장범진;남하윤;신혜민;윤동민;이승국;장인화;김성철
    • 대한방사선기술학회지:방사선기술과학
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    • 제46권5호
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    • pp.409-415
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    • 2023
  • Although pediatric X-ray examinations are continuously increasing, there are not many studies on the radiation exposure to children and X-ray examination assistants according to X-ray Exposure conditions. Accordingly, we measured the radiation exposure dose of pediatric and X-ray examination assistants according to the standard guidelines and clinical average X-ray Exposure conditions when X-ray examination 10-year-old children. The effective dose and organ dose to pediatric were measured using an Dose area production meter and Monte Carlo-based PCXMC program, and the exposure dose of X-ray examination assistants was measured using an ion-chamber. When performing abdominal supine AP projection, the effective dose to children was up to 2.38 times higher under clinical average X-ray Exposure conditions than the standard guidelines. In addition, during abdominal supine AP projection, the radiation exposure dose to the X-ray examination assistants was highest on the hands at 0.0148 ~ 0.0709 mSv, and exposure dose could be reduced by up to 35% when wearing protective gloves. In conclusion, because the X-ray Exposure conditions used in clinical are unnecessarily high, unnecessary medical radiation exposure could be reduced if appropriate X-ray Exposure conditions and the radiation field area were minimized and the assistant wore shielding gloves.

Induction of Antioxidant Enzymes in Phloroglucinol Treated Cells

  • Kang Kyoung Ah;Lee Kyoung Hwa;Chae Sungwook;Ahzang Rui;Jung Myung Sun;Ham Young Min;Baik Jong Seok;Lee Nam Ho;Hyun Jin Won
    • 한국환경성돌연변이발암원학회지
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    • 제25권4호
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    • pp.129-133
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    • 2005
  • We investigated the cytoprotective effect of phloroglucinol, which was isolated from Ecklonia cava (brown seaweed), against oxidative stress induced cell damage in Chinese hamster lung fibroblast(V79-4) cells. Phloroglucinol was found to scavenge intracellular reactive oxygen species (ROS) generated by $\gamma-ray$ radiation. In addition, Phloroglucinol inhibited cell damage induced by radiation through scavenging ROS. Phloroglucinol increased the superoxide dismutase and glutathione peroxidase activity, Taken together, the results suggest that phloroglucinol protectes V79-4 cells against oxidative damage by enhancing the cellular antioxidant enzymes activity.

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