• Title/Summary/Keyword: Department of Neurosurgery

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Fires and Burns Occurring in an Electrocautery after Skin Preparation with Alcohol during a Neurosurgery

  • Chae, Sang-Bae;Kim, Woo-Kyung;Yoo, Chan-Jong;Park, Cheol-Wan
    • Journal of Korean Neurosurgical Society
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    • v.55 no.4
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    • pp.230-233
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    • 2014
  • While there are reports regarding burns occurring to patients during the surgery, there are little reports concerning the incidents of the burns related to neurosurgical operations. Moreover, in Korea, even surveys and statistics on the incidents of burns in operating rooms are not known. This report explores burns occurring to a patient in an electrocautery scenario after disinfecting the surgical site with alcohol during the preparation of a neurosurgical operation in an operating room where there is much exposure to oxygen. The authors show a case of a 33-year-old male patient who undergoing evacuation of hematoma on occipital lesion, suffered second degree burns as a result of surgical fires.

LncRNA-IMAT1 Promotes Invasion of Meningiomas by Suppressing KLF4/hsa-miR22-3p/Snai1 Pathway

  • Ding, Yaodong;Ge, Yu;Wang, Daijun;Liu, Qin;Sun, Shuchen;Hua, Lingyang;Deng, Jiaojiao;Luan, Shihai;Cheng, Haixia;Xie, Qing;Gong, Ye;Zhang, Tao
    • Molecules and Cells
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    • v.45 no.6
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    • pp.388-402
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    • 2022
  • Malignant meningiomas often show invasive growth that makes complete tumor resection challenging, and they are more prone to recur after radical resection. Invasive meningioma associated transcript 1 (IMAT1) is a long noncoding RNA located on Homo sapiens chromosome 17 that was identified by our team based on absolute expression differences in invasive and non-invasive meningiomas. Our studies indicated that IMAT1 was highly expressed in invasive meningiomas compared with non-invasive meningiomas. In vitro studies showed that IMAT1 promoted meningioma cell invasion through the inactivation of the Krüppel-like factor 4 (KLF4)/hsa-miR22-3p/Snai1 pathway by acting as a sponge for hsa-miR22-3p, and IMAT1 knockdown effectively restored the tumor suppressive properties of KLF4 by preserving its tumor suppressor pathway. In vivo experiments confirmed that IMAT1 silencing could significantly inhibit the growth of subcutaneous tumors and prolong the survival period of tumor-bearing mice. Our findings demonstrated that the high expression of IMAT1 is the inherent reason for the loss of the tumor suppressive properties of KLF4 during meningioma progression. Therefore, we believe that IMAT1 may be a potential biological marker and treatment target for meningiomas.

Disseminated Tuberculosis of Central Nervous System : Spinal Intramedullary and Intracranial Tuberculomas

  • Lim, Yu Seok;Kim, Sung Bum;Kim, Min Ki;Lim, Young Jin
    • Journal of Korean Neurosurgical Society
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    • v.54 no.1
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    • pp.61-64
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    • 2013
  • As a cause of spinal cord compression, intramedullary spinal tuberculoma with central nervous system (CNS) involvement is rare. Aurthors report a 66-year-old female presented with multiple CNS tuberculomas including spinal intramedullary tuberculoma manifesting paraparesis and urinary dysfunction. We review the clinical menifestation and experiences of previous reported literature.

`Y-stenting` for Endovascular Coiling of Small Basilar Tip Aneurysm

  • Cho, Chun-Sung;Kim, Young-Joon;Lee, Sang-Koo;Cho, Maeng-Ki
    • Journal of Korean Neurosurgical Society
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    • v.40 no.1
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    • pp.31-34
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    • 2006
  • This 58-year-old woman was transferred from a local hospital due to symptoms of acute headache and decreased consciousness. Computed tomography revealed a subarachnoid hemorrhage with blood clot in prepontine cistern. On the first day in the hospital, diagnostic cerebral angiography revealed a basilar tip aneurysm. We performed basilar artery to bilateral posterior cerebral artery[PCA] stent placement to reconstruct the basilar artery apex.

Postpartum Cerebral Angiopathy - Presenting with Both Hemorrhagic and Ischemic Stroke

  • Kim, Sung-Ho;Chang, Chul-Hoon;Kim, Sang-Woo;Choi, Byung-Yon
    • Journal of Korean Neurosurgical Society
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    • v.38 no.4
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    • pp.299-302
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    • 2005
  • Postpartum cerebral angiopathy[PPCA] is a benign and, reversible cerebrovascular disease in the postpartum period. The authors report here a 29-year-old woman who had severe headache, very poor consciousness and visual disturbances as the symptoms of PPCA. The clinical and radiological evaluation and treatment of this patient are disscussed.

Intradural Extramedullary Non-infiltrated Solitary Metastatic Tumor

  • Jung, Young-Jin;Kim, Sang-Woo;Chang, Chul-Hoon;Cho, Soo-Ho
    • Journal of Korean Neurosurgical Society
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    • v.37 no.6
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    • pp.466-468
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    • 2005
  • Spinal intradural extramedullary non-infiltrated solitary metastasis is very rare. We report a case of intradural extramedullary carcinoma to the T9 nerve root, which mimiking a nerve sheath tumor. Pathology reveals metastatic adenocarcinoma. We discuss the feature of mechanism and pathogenesis and management strategy follows.

Unintended Complication of Intracranial Subdural Hematoma after Percutaneous Epidural Neuroplasty

  • Kim, Sung Bum;Kim, Min Ki;Kim, Kee D.;Lim, Young Jin
    • Journal of Korean Neurosurgical Society
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    • v.55 no.3
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    • pp.170-172
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    • 2014
  • Percutaneous epidural neuroplasty (PEN) is a known interventional technique for the management of spinal pain. As with any procedures, PEN is associated with complications ranging from mild to more serious ones. We present a case of intracranial subdural hematoma after PEN requiring surgical evacuation. We review the relevant literature and discuss possible complications of PEN and patholophysiology of intracranial subdural hematoma after PEN.

A Subcortical Anaplastic Meningioma

  • Kim, Chang-Hyun;Park, Seong-Hyun;Hwang, Jeong-Hyun;Hamm, In-Suk
    • Journal of Korean Neurosurgical Society
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    • v.37 no.3
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    • pp.235-237
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    • 2005
  • Meningioma without dural attachment usually occurs in the intraventricular region, the pineal region, and the sylvian fissure. However, subcortical meningioma located far from such locations is extremely rare. The authors report a case of subcortical anaplastic meningioma without any dural attachment in a 41-year-old woman.