• Journal of Dental Anesthesia and Pain Medicine
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• 제15권2호
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• pp.101-103
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• 2015

In oral and maxillofacial surgery, many complications associated with nasotracheal tube can be caused. In this case, we reported ballooning tube damage of nasotracheal tube during orthognathic double-jaw surgery and replacement of tube through cut down of tube and tube exchange using airway exchange catheter. The patient scheduled for high Le Fort I osteotomy and bilateral sagittal split osteotomy was intubated nasotracheally with nasal endotracheal tube. During maxilla osteotomy, air bubble was detected in the oral blood. In spite of our repeated ballooning, the results were the same so we changed damaged tube using airway exchange catheter aseptically. Tiny and superficial cutting site was detected in the middle of pilot tube. As we know in our case, tiny injury impeded a normal airway management and prevention is important.

• 대한장애인치과학회지
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• 제12권2호
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• pp.72-76
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• 2016

저자는 뇌병변 장애와 보행장애로 반복적인 외상성 치아손상을 받은 환아의 치료를 시행하였다. 최근 실활된 미성숙 영구치의 계속된 치근 형성을 위해 재생적 근관치료 술식이 많이 시도되어 성공적인 결과를 보이고 있다. 하지만 장애로 인해 반복적인 외상의 위험을 가진 환아에서 치수조직의 재생 보다는 치근단형성술을 통한 치근단의 폐쇄와 근관 충전이 비용과 장기적인 예후의 측면에서 유리한 치료방법이 될 수 있음을 확인하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제37권6호
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• pp.439-447
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• 2011

Introduction: In today's society, the rapid and appropriate care of the dental emergency patients is much more important. So, a retrospective study on the characteristics of emergency dental injuries and diseases will be very meaningful. Materials and Methods: This retrospective clinical study was carried by reviewing the radiographic films and emergency chart of 11,493 patients who had visited the emergency room of Hallym Sacred heart Hospital and were treated in the Department of Oral and Maxillofacial Surgery from January 2006 to December 2010. Results: The male to female ratio was 1.9:1. The highest monthly incidence was observed in May (10.4%) and June (8.9%) and the peak age distribution was the first decade (56.0%), followed by the second decade (16.0%). Trauma was the most common cause in dental emergency patients, followed in order by toothache, odontogenic infection, temporomandibular joint (TMJ) disorder and oral hemorrhage. Soft tissue injury was most prevalent in the trauma group, followed by tooth injury and facial bone fractures. In the tooth injury group, tooth fracture (56.7%) showed the highest incidence followed in order by tooth subluxation (18.2%), tooth concussion (16.9%), tooth avulsion (11.5%) and alveolar bone fractures (3.7%). In the facial bone fracture group, mandibular fractures (81.8%) showed the highest incidence followed in order by maxilla fractures (15.7%), nasal bone fractures (9.0%), zygomaticomaxillary complex fractures (5.4%), orbital bone fractures (2.5%). In mandibular bone fractures, the most common location was the symphysis (70.1%), followed in order by the mandibular angle (33.0%), mandibular condyle (22.8%) and mandibular body (13.6%). In the infection group, a submandibular space abscess (46.2%) was most common followed in order by a buccal space abscess (17.4%), canine space abscess (16.9%) and submental space abscess (12.3%). TMJ dislocation (89.3%) showed the highest incidence in the TMJ disorder group, followed by TMJ derangement (10.7%). In the other group, a range of specific symptoms due to post operation complications, trigeminal neuralgia, chemical burns and foreign body aspiration were reported. Conclusion: For the rapid and appropriate care of the dental emergency patients, well-organized system should be presented in oral and maxillofacial surgery. And it is possible under analysis of pattern and the variation of the dental emergency patients.

• 대한소아치과학회지
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• 제35권4호
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• pp.642-651
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• 2008

본 연구는 2003년 1월부터 2007년 7월까지 전남대학교 병원 소아치과와 응급실에 치아 외상을 주소로 내원한 환자 570명(치아수: 1394개)을 대상으로 연령, 성별분포, 발생원인 및 장소, 손상 받은 치아의 위치 및 유형, 초진시 처치 등에 대한 조사를 통해 외상에 대한 적절한 진단과 치료에 도움이 되고자 시행하였다. 1. 성별에 따른 발생빈도는 1.9:1로 남자의 비율이 높았고, 나이에 따른 발생 빈도는 1세, $6{\sim}8$세, $17{\sim}18$세 때 높았다. 2. 외상의 원인은 유치열과 혼합치열에는 넘어진 경우가 가장 많았으며 영구치열에서는 교통사고와 싸움으로 인한 손상 빈도가 높았다. 외상을 입은 장소는 유치열은 집에서, 혼합치열, 영구치열에는 길에서 비율이 높았다. 3. 외상시 손상 받은 치아의 위치는 유치와 영구치 모두 상악 중절치의 비율이 높았다. 손상의 유형은 유치와 영구치 모두 치주조직의 손상이 많았는데, 유치는 아탈구, 진탕, 함입 순이었으며, 영구치는 아탈구, 진탕, 완전탈구 순이었다. 4. 초진시의 처치는 특별한 처치 없이 경과를 관찰하는 경우가 대부분이었으며, 유치는 33.1%, 영구치에서는 44.5%의 재 내원률을 보였다. 치주조직 손상 후 유치는 20.3%, 영구치는 26.6%의 치수 괴사율을 보였다.

• 대한치과마취과학회지
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• 제12권2호
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• pp.121-123
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• 2012

Nasotracheal intubation is an essential procedure during general anesthesia for dental treatment. Fiberoptic intubation is best accomplished by those who perform it as part of their daily practice. But nasal approach of fiberoptic intubation has some complications such as epistaxis and laryngeal injury. Especially, epistaxis is common and it make fiberoptic intubation because of limited view. When the epistaxis obstruct the field of vision we have to withdraw the fiberoptic bronchoscope and consider the other method for securing the airway. We succeeded in securing the airway of patient who had epistaxis during the fiberoptic nasotracheal intubation without withdrawing the fiberoptic bronchoscope. We used blind intubation guided by light source placed the tip of fiberoptic bronchscope applied to lightwand intubation.

• 대한치과의사협회지
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• 제46권6호
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• pp.384-393
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• 2008

Many dental surgeries including implant surgery, orthognathic surgery etc, have possibility of neurologic injury. As neurosensory dysfunction has no definitive treatment modality and shows slow recovery, patients have discomforts and make the legal conflicts with surgeons. The purpose of this study was to survey the types and subjective evaluation of patients with neurosensory dysfuction after dental surgery. This study included 66 patients with postoperative neurosensory dysfunction who were operated at Seoul National University Bundang Hospital from Dec 2003 to Jun 2007. Male were 28 and female were 38. Age was from 17 to 74 years old. The results of subjective evaluation of neurosensory dysfunction were as followings. 1. The sites of the altered sensation were chin, lip, tooth, tongue and so on. 2. 40.7% of the patients didn't explain accurately about their symptoms. 29.2% of the patients expressed anesthesia and 26.2% mild discomfort. 3. The altered sensation was expressed mostly in touching, mastication and speaking. 52.3% of the patients suggested that their symptoms always existed. 4. Neuropathic pain existed in 44.6% of the patients. 48.3% of the patients suggested that pain was triggered by touching. Neuropathic pain always existed in 41.4% of the patients. 5. Patients showed negative responses on the question that they will take operations which cause the risk of neurosensory dysfunction in the future. The objective and subjective evaluation about the altered sensation after nerve injury nerver coincide. The subjective complaint can affect the result of treatment and daily life negatively.

• The Korean Journal of Physiology and Pharmacology
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• 제22권2호
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• pp.145-153
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• 2018

The subgranular zone (SGZ) of hippocampal dentate gyrus (HDG) is a primary site of adult neurogenesis. Toll-like receptors (TLRs), are involved in neural system development of Drosophila and innate immune response of mammals. TLR2 is expressed abundantly in neurogenic niches such as adult mammalian hippocampus. It regulates adult hippocampal neurogenesis. However, the role of TLR2 in adult neurogenesis is not well studied in global or focal cerebral ischemia. Therefore, this study aimed to investigate the role of TLR2 in adult neurogenesis after photochemically induced cerebral ischemia. At 7 days after photothrombotic ischemic injury, the number of bromodeoxyuridine (BrdU)-positive cells was increased in both TLR2 knock-out (KO) mice and wild-type (WT) mice. However, the increment rate of BrdU-positive cells was lower in TLR2 KO mice compared to that in WT mice. The number of doublecortin (DCX) and neuronal nuclei (NeuN)-positive cells in HDG was decreased after photothrombotic ischemia in TLR2 KO mice compared to that in WT mice. The survival rate of cells in HDG was decreased in TLR2 KO mice compared to that in WT mice. In contrast, the number of cleaved-caspase 3 (apoptotic marker) and the number of GFAP (glia marker)/BrdU double-positive cells in TLR2 KO mice were higher than that in WT mice. These results suggest that TLR2 can promote adult neurogenesis from neural stem cell of hippocampal dentate gyrus through increasing proliferation, differentiation, and survival from neural stem cells after ischemic injury of the brain.

• Journal of Oral Medicine and Pain
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• 제37권4호
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• pp.251-256
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• 2012

오늘날 삶의 질에 대한 관심이 고조되면서 일반 대중에게서도 레져 및 스포츠가 활성화됨에 따라 구강악안면영역 외상의 발생빈도도 높아지고 있다. 이러한 구강악안면영역의 외상을 예방하기 위해 구강보호장치 사용의 중요성이 커지고 있으며, 그 중 가장 많이 사용되는 것이 마우스가드이다. 마우스가드는 1) 치아에 가해지는 충격을 흡수하고 변형시켜 치아의 손상을 방지; 2) 입술, 혀, 치은 등 연조직의 열상을 예방; 3) 충격의 발생 시 반대측 치아가 접촉되는 것을 예방; 4) 하악골을 안정화시켜 하악각 또는 하악과두의 파절을 유발할만한 충격을 흡수시킴; 그리고 5) 목 또는 뇌손상을 예방할 수 있다. 이렇듯 마우스가드가 구강악안면영역의 외상방지에 효과적이지만, 운동선수나 일반 대중들에게는 널리 보급되어 있지 않고 그 중요성에 대한 인식률도 저조한 실정이다. 레져나 스포츠 활동 시 나타날 수 있는 구강악안면 외상 예방에 가장 효과적인 마우스가드의 종류, 재료, 제작 시 고려할 사항 등을 알아보고, 사용실태에 대한 고찰을 통해 마우스가드의 중요성에 대한 인식과 대중화에 도움이 되고자 한다.

• The Korean Journal of Physiology and Pharmacology
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• 제14권3호
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• pp.157-161
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• 2010

Heat shock proteins (HSPs) are specifically induced by various forms of stress. Hsp70.1, a member of the hsp70 family is known to play an important role in cytoprotection from stressful insults. However, the functional role of Hsp70 in motor function after spinal cord injury (SCI) is still unclear. To study the role of hsp70.1 in motor recovery following SCI, we assessed locomotor function in hsp70.1 knockout (KO) mice and their wild-type (WT) mice via the Basso, Beattie and Bresnahan (BBB) locomotor rating scale, before and after spinal hemisection at T13 level. We also examined lesion size in the spinal cord using Luxol fast blue/cresyl violet staining. One day after injury, KO and WT mice showed no significant difference in the motor function due to complete paralysis following spinal hemisection. However, when it compared to WT mice, KO mice had significantly delayed and decreased functional outcomes from 4 days up to 21 days after SCI. KO mice also showed significantly greater lesion size in the spinal cord than WT mice showed at 21 days after spinal hemisection. These results suggest that Hsp70 has a protective effect against traumatic SCI and the manipulation of the hsp70.1 gene may help improve the recovery of motor function, thereby enhancing neuroprotection after SCI.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제36권1호
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• pp.43-52
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• 2010

Purpose: To research about maxillofacial traumatic injuries of children in aspects of gender difference, various incidence rates between age, trauma type, cause, monthly and daily incidence rate, type of tooth damage, gingival damage, soft tissue damage, and type of facial bone fracture. Materials and methods: Study group consisted of children under 15 years of age who visited Dental Hospital, School of Dentistry, Kyung Hee University from 2004/7/1 to 2007/6/30 with chief complaint of oral and maxillofacial traumatic injuries. 1,559 cases of traumatic injuries were studied from 1,556 (1,004 male, 552 female) children. Conclusion: 1. There were slightly more boys than girls, giving a male-to-female ratio of 1.82:1.0. The 1-3 year old boys and girls had the highest number of traumatic injuries. 2. Of the 1,556 patients, 68.63% had soft tissue injuries, 50.22% had periodontal injuries, 29.89% had teeth injuries, and 3.85% had maxillofacial bone fractures. 3. Falling down was the most common cause of injury in both sexes. 4. The months with the highest incidence rates were in order May (12.12%), June (11.74%), and October (11.13%). Most of the injuries occurred on weekends. 5. The most common tooth injury was uncomplicated crown fracture, and the most common periodontal injury was subluxation. The majority of traumatizes teeth were the upper central incisors. 6. The most common soft tissue injury was intraoral lacerations. 7. Mandibular fractures were most frequent in facial bone fractures; symphysis, condylar head, and angle fractures were most frequent in mandibular fractures; maxillary and nasal bone fractures were most frequent in midfacial bone fractures.