• 동의신경정신과학회지
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• 제32권3호
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• pp.285-302
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• 2021

Objectives: To examine the effect of long-term Korean medicine treatment on mild cognitive impairment (MCI). Methods: This study was conducted on two patients who were diagnosed with mild cognitive impairment and received long-term Korean medicine treatment. In order to evaluate the degree of cognitive decline, SNSB and K-MMSE were performed 2~3 times at the first visit and during the treatment process. Results: Both cases 1 and 2 were diagnosed with MCI with a high possibility of developing dementia. In case 1, MCI progressed to early dementia at one year after the diagnosis of MCI. However, in case 2, that MCI status was maintained without progressing to dementia for 4 years after the diagnosis of MCI. The cause of such difference in the course of MCI might be attributed to the fact that Case 1 had lower K-IADL level but higher SGDS level than Case 2 at the time of initial diagnosis, with weak family support and irregular herbal medicine intake. Conclusions: Korean medicine treatment could improve and manage symptoms of cognitive decline due to MCI.

• 한국조리학회지
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• 제2권
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• pp.59-87
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• 1996

This study has been done by giving the guide when development of menu or doing marketing strategy in Hotel Restaurant. All products and service has a regular course from induction in market to disappear, so it shall be come out Products Life Cycle theory. In eating business, under the tendency and existing cycle to change menu by taste of customers, liking variation, change of periodic status (environment), MLC(Menu Life Cycle) shall be advised by application PLC(Products Life Cycle) in the process of induction of some menu first and spreading the same business field and then deletion (disappearance) from menu because of no popular. In Emergence Stage, it shall be tried to inform new menu through Cooking Contest, presentation of new menu, free sampling party and others. In Growth Stage, it shall be changed package menu or set menu. In Maturity Stage, it shall be provided complimentary ticket, gift coupon or discount for the customers with some degree of selling record in order to increase using frequency and selling amount after insure new customers. In Decline Stage, it shall be groped for entry underdeveloped country or less advance nation, but there is no possibility to devote in enterprise, it shall be planned substitute menu development in order to withdraw. By inducting MLC concept, it shall be provided the available informations such as“how could some menu be circulate in some restaurant”“Accordingly do strengthen promotion activities or go to low developed area or overseas, or delete it from menuitems and so on”. In the time of decline some menu, it is judged to the time of plan(preparation) of new menu development. In the broad view, when consideration of the concept of menu life cycle, it shall be possible to know which menu is decayed and which menu is developed newly or grown-up, so it shall be provided the important information to estimate the tendency of changing menu and set-up a menu development plan.

• 대한토목학회논문집
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• 제37권6호
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• pp.1095-1108
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• 2017

항만 배후지역은 역사적으로 계획된 공간이기 보다는 항만공간 개발에 의해 밀려나듯이 만들어진 공간이라고 할 수 있다. 이러한 이유로 인해 항만배후지역의 거주환경은 과거부터 현재까지 매우 열악한 실정이며, 최근 항만공간의 기능 변화에 따라 재개발 되는 사례가 늘고 있는 실정이다. 하지만 국내 항만공간 개발은 항만공간에만 국한되어 있으며 여전히 항만 배후지역의 거주환경 개선에 대한 대비는 미비한 실정이다. 이에 본 연구를 통해 항만배후지역의 거주환경 개선을 위한 도시재생 시나리오 도출을 위하여 항만 배후지역의 쇠퇴정도를 진단, 분석하였다. 이후 쇠퇴화가 진행되고 있는 항만 배후지역의 거주성 향상을 위한 도시재생 요소를 도출하고, 각 요소가 적용된 시나리오를 구축하였다.

• Steel and Composite Structures
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• 제37권3호
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• pp.353-369
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• 2020

Eight cold-formed thin-walled steel beams were performed to investigate the effect of corrosion damage on the flexural behavior of steel beams. The relationships between failure modes or load-displacement curves and corrosion degree of steel beams were investigated. A series of parametric analysis with more than forty finite element models were also performed with different corrosion degrees, types and locations. The results showed that the reduction of cross-section thickness as well as corrosion pits on the surface would lead to a decline in the stiffness and flexural capacity of steel beams, and gradually intensified with the corrosion degree. The yield load, ultimate load and critical buckling load of the corroded specimen IV-B46-4 decreased by 22.2%, 26% and 45%, respectively. The failure modes of steel beams changed from strength failure to stability failure or brittle fracture with the corrosion degree increasing. In addition, thickness damage and corrosion pits at different locations caused the degradation of flexural capacity, the worst of which was the thickness damage of compression zone. Finally, the method for calculating flexural capacity of corroded cold-formed thin-walled steel beams was also proposed based on experimental investigation and numerical analysis results.

• 사상체질의학회지
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• 제12권2호
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• pp.171-183
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• 2000

1. Back ground and purpose An experimental study has done to examine the effect of defense and cure gastric mucasal damage of Mokdan-pijihwang-tang. 2. Methods Mice had intragastric injected with MJ extract before indomethacin treatment which induces homorrhage infarct and erosion artificially. Degree of lipid peroxidation, general morphology, change of mucous cell, the distribution of PNA, ICAM and distribution of apoptotic cell were objected. (Abbreviation) MJ : Mokdanpijihwang-tang, PNA : Peanut Agglutinin, ICAM : Intercellular Adhesion Molecule 3 Results 1) The degree of lipid peroxidation in INDO-group had increased conspicuously than control group. But the degree of lipid peroxidation in MJ-group had decreased than INDO-group and these decline had probability. 2) After indomethacin treatment, hemorrhage infarct and erosion had increased in stomach body. But in MJ-group, the configuration is normal, except the group intragastric injected with MJ extract at hour 24 before indomethacin treatment. 3) Surface mucous cell and neck mucous had disappeared in INDO-group. But in MJ-group tormal distribution had shown like control group except the group intragastric injected with MJ extract at hour 24 before indomethacin treatment. 4) PNA positive reaction had not shown in INDO-group. But medium PNA positive reaction had shown In Mj-group. 5) ICAM positive reacted cell had shown in INDO-group. The decrease of ICAM positive cell were shown than INDO-group. 6) A number of apoptotic cell was distributed in hemorrhagic erosion. A few number of apoptotic cell was distributed in MJ-group except some surface mucous. 4. Conclusion These results suggest that MJ has an effect on cure of gastric mucosal damage.

• 펄프종이기술
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• 제47권6호
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• pp.22-40
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• 2015

Cellulose fibers is one of the most abundant in nature. It has many distinctive features: abundant in nature, biodegradable, non-toxic, eco-friendly, sustainable, easy to fabricate, hydrophilic, and cost-effective. Cellulose fibers, known as pulp, is produced from cellulose-containing materials by the pulping process. As the raw material, wood has been most commonly used while recycled pulp has been also used to some degree. Thus, pulp usually refers to wood pulp. Generally, the pulp and paper industry is regarded as the commodity market where the cost should be much more important than the quality. It also belongs to a mature market where the growth is slow, or even in decline. Accordingly, technological development has been rather stagnant for the industry. Recently, however, the pulp and paper industry has faced very serious challenges. First, due to digital technology, there has been a steady decline in the need for pulp and paper products. The digital industry has continuously replaced printed products such as books, newspapers, and magazines. Second, there has been a trend initiated by developed countries to limit the use of wood as the raw material for the sake of environmental protection. This forces the industry to find a more efficient use of wood pulp as well as finding alternative, non-wood sources. Third, as an individual becomes wealthier and more conscious of health-care, the quality of a product becomes more important than the cost. Thus, a paradigm shift is needed from the cost-conscientious to the quality conscientious. The objective of this article is to review the technologies aimed at engineering cellulose fibers for producing high-value added paper products.

• 한국콘텐츠학회논문지
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• 제20권10호
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• pp.326-337
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• 2020

본 연구의 목적은 도시 고령자와 농촌 고령자의 사회참여활동 유형이 인지기능 손상 정도(정상, 경증 인지기능저하, 중증 치매 의심)에 미치는 영향을 분석하는 것이다. 연구목적을 위해 6차(2016년)와 7차(2018년) 고령화 연구패널 조사 데이터 중 55세 이상 고령자 5,668명의 자료를 사용하여 다항 로지스틱 회귀분석을 하였다. 분석결과는 어떤 유형이든지 사회참여활동 하는 것이 인지기능 장애 위험을 줄여준다는 것은 도시와 농촌 둘 다 일관되게 유의하였으나, 도움이 되는 사회참여활동 유형이 도시와 농촌 간 차이가 있었다. 즉, 도시와 농촌에 사는지에 따라 정상군에서 인지기능저하 또는 치매 의심이 될 위험을 낮추는 데 도움이 되는 사회참여 활동 유형과 인지기능저하에서 치매 의심이 될 위험을 낮추는 데 유의한 유형이 달랐다. 따라서 인지기능 장애를 예방하고 치매 중증도를 완화하는 데 사회참여활동을 적극적으로 권장돼야 하며 적절한 지원이 필요하다는 것을 보여준다. 그리고 도시와 농촌의 차이를 고려한 정책과 개입이 요구됨을 함의한다.

• 한국방재학회 논문집
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• 제10권5호
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• pp.67-73
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• 2010

많은 기회요소와 편의성이 존재하기 때문에 도시에는 많은 인구와 건물이 집중되어 있다. 이러한 이유로 인하여 재해 발생 가능성이 높고 재해가 발생하면 그 피해는 치명적이다. 본 연구는 우리나라 도시특성에 맞는 실용적인 재해 위험도 평가방법을 제시하는데 있으며, 사례지역으로 충청북도 청주시를 대상으로 평가하였다. 화재위험도, 건물붕괴위험도, 대피위험도, 가스폭발 위험도를 포함한 종합위험도를 분석하고 적용한 결과, 현재 도심공동화 현상이 나타나는 북문로 일대가 위험성이 가장 높게 나타나는 것으로 분석되었다. 이 일대는 구시가지로 재난의 대책 및 정비가 이루어지지 않았음을 예상할 수 있으며 시급한 정비가 이루어져야 된다고 판단된다.

• 한국임상수의학회지
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• 제18권1호
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• pp.7-13
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• 2001

Depending on the degree of exocrine pancreatic insufficiency, there are inconsistent values in the serum trypsin-like immunoreactivity (TLI), hematology, and serology. To determine the correlation between those values and complete pancreatic insufficiency, 10 pancreatectomized dogs as the treated group and 10 sham operation dogs as control group were used. The entire treated group showed significant decrease in serum TLI level from 2.63$\pm$0.20 ng/ml (day 0) to 1.81$\pm$0.43 ng/ml at day 1 after the pancreatectomy (p<0.05) and the decline maintained till the end of the experiment. Blood glucose level gradually increased, but albumin level showed significant decrease (p<0.05) at day 1 and maintained the decline. Three clinical signs were observed such as depression, vomiting, and diarrhea. The entire treated group showed diarrhea throughout the experiment, but depression and vomiting were gradually diminished. The activity of serum alkaline phosphatase in the treated group increased till day 2 then decreased, on the other hand, control group showed continuous increase till day 4, and then decreased. Only experimental group showed the increased alanine aminotransferase activity at day 1. Serum lipase activity in the treated group jumped up at day 1 and then dropped down, which was even lower than the control. Regarding serum amlyase activity gradually decreased. According to these results, the assay of trypsin-like immunoreactivity showed the consistent result, so it suggests that TLI is an useful tool to determine the pancreatic exocrine function and possible diagnosis of exocrine pancreatic insufficiency compared to the simple assay of plasma amylase and lipase.

• 대한한의학회지
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• 제42권2호
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• pp.98-106
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• 2021

본 증례보고에서는 과로 후 공황장애가 온 44세 남성 환자를 상한론 변병진단체계(傷寒論 辨病診斷體系)에 입각하여 태양병(太陽病)으로 진단하고 15조문의 계지탕(桂枝湯)을 약 6개월 동안 투여한 결과 주소증인 심계항진, 가슴답답함, 기역(氣逆), 호흡곤란을 포함한 제반 증상들이 호전되는 치료적 효과를 확인할 수 있었다.