• Title/Summary/Keyword: Degradation model

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Influence of barley grain treated with alkaline compounds or organic extracts on ex vivo site and extent of digestion of starch

  • Naseroleslami, Reza;Mesgaran, Mohsen Danesh;Tahmasbi, Abdolmansour;Vakili, Seyed Alireza;Ebrahimi, Seyed Hadi
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.2
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    • pp.230-236
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    • 2018
  • Objective: Two ex vivo experiments were conducted to verify the effect of barley grain (Nusrat cultivar) treated with alkaline compounds (AC) including alum, ammonium, and sodium hydroxide or cation-exchanged organic extracts (OE) prepared from alfalfa hay, sugar beet pulp and Ulva Fasciata, on extent and digestion of starch. Methods: In the first study, the in vitro first order disappearance kinetic parameters of dry matter (DM), crude protein (CP) and starch were estimated using a non-linear model ($D_{(t)}=D_{(i)}{\cdot}e^{(-k_d{\cdot}time)}+I$, where: $D_{(t)}$ = potentially digestible residues at any time, $D_{(i)}$ = potentially digestible fraction at any time, $k_d$ = fractional rate constant of digestion (/h), I = indigestible fraction at any time). In the second experiment, the ruminal and post-ruminal disappearance of DM, CP, and starch were determined using in situ mobile nylon bag. Results: Barley grains treated with alum and alfalfa extract had a higher constant rate of starch digestion (0.11 and 0.09/h) than others. Barley grain treated with OE had a higher constant rate of CP digestion and that of treated with AC had a higher constant rate of starch digestion (0.08 and 0.11/h) compared with those of the other treatments. The indigestible fraction of starch treated with alum and sugar beet pulp extract was higher than that of the control group (0.24 and 0.25 vs 0.21). Barley grain treated with AC and OE had significant CP disappearance in the rumen, post-rumen and total tract, and also starch disappearance for post-rumen and total tract compared with the untreated (p<0.001). Conclusion: This study demonstrated that AC and OE might have positive effects on the starch degradation of the barley grain. In addition, treating barley grain with alum and sugar beet pulp extract could change the site and extend digestion of protein and starch.

Simple Material Budget Modeling for a River-Type Reservoir (하천형 저수지의 단순 물질수지 모델링)

  • Yoon, Seong-Kyu;Kong, Dong-Soo;Bae, Wookeun
    • Journal of Korean Society on Water Environment
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    • v.26 no.3
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    • pp.420-431
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    • 2010
  • Simple material budget models were developed to predict the dry season water quality for a river-type reservoir in Paldang, Republic of Korea. Of specific interest were the total phosphorus (TP), chlorophyll ${\alpha}$ (Chl. ${\alpha}$), 5-day biochemical oxygen demand (BOD), and chemical oxygen demand (COD). The models fit quite well with field data collected for 20 years and have enabled the identification of the origins of organic materials in the reservoir. The critical hydraulic load that determines the usability of phosphorus for algal production appeared to be about $1.5m\;d^{-1}$. When a hydraulic load was smaller than the critical value, the concentrations of $Chl.{\alpha}$, COD, and BOD in the reservoir water became sensitive to internal algal reactions such as growth, degradation, and settling. In spite of the recent intensive efforts for organic pollutant removal from major point sources by central and local governments, the water quality in the reservoir had not been improved. Instead, the concentration of COD increased. The model analysis indicated that this finding could be attributed to the continuing increase of the algal production in the reservoir and the allochthonous load from non-point sources. In particular, the concentrations of COD and BOD of algal origin during 2000~2007, each of which is comprised of approximately one half of the total, were approximately 2.5 times higher than those observed during 1988~1994 and approximately 1.3 times higher than those between 1995~1999. The results of this study suggested that it is necessary to reduce the algal bloom so as to improve the water quality of the reservoir.

Biodegradation of Phenanthrene by Transformant Trametes versicolor MrP1 (구름버섯의 형질전환체 Trametes versicolor MrP1에 의한 Phenanthrene의 생분해)

  • Choi, Yun-Seong;Choi, Hyoung-Tae;Song, Hong-Gyu
    • Korean Journal of Microbiology
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    • v.43 no.4
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    • pp.273-278
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    • 2007
  • As a model compound of PAHs (polycyclic aromatic hydrocarbons) phenanthrene has been regarded as a toxic material, mutagen and carcinogen in various animals. Biodegradation conditions of phenanthrene such as pH, temperature, shaking speed, stabilizer and cofactor of degrading enzymes were investigated with Trametes versicolor and its transformant T. versicolor MrP1 in YMG medium, minimal medium and soil microcosm. T. versicolor MrP1 can overexpress mrp gene encoding Mn-repressed peroxidase that is involved in fungal degradation. Biodegradations of phenanthrene by T. versicolor and T. versicolor MrP1 were optimally performed in conditions of weak-acid (pH 6.0), $30^{\circ}C$, shaken culture and medium containing 5 mM veratryl alcohol or tryptophan. In these optimal conditions, biodegradation of phenanthrene by T. versicolor MrP1 is 31% higher than that of wild type strain in a minimal medium for 20 days. Biodegradation of phenanthrene by T. versicolor MrP1 was also higher than that of wild type in soil microcosm. T. versicolor MrP1 can be a excellent candidate for the bioremediation of PAHs contaminated environments.

Optimization Design in Time Domain on Impulse GPIR System (임펄스 GPIR시스템의 시간영역 최적화 설계)

  • Kim, Kwan-Ho;Park, Young-Jin;Yoon, Young-Joong
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.46 no.3
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    • pp.32-39
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    • 2009
  • In this paper, system optimization design technique of an impulse ground penetrating image radar (GPIR) in time domain is proposed to improve depth resolution of the system. For the purpose, time domain analysis method of key components such as impulse generator and UWB antenna is explained and by simulation, parameters of each component are determined. In particular, by standardizing the impulse signal, spectrum efficiency of a radiated impulse signal is improved and a U-shaped planar dipole antenna for a UWB antenna is developed. By equipping a parabolic metal reflector with the proposed antenna, external noise is prevented and the ability of radiating an input impulse into ground is improved. In addition, to remove ringing effect of the propose antenna which causes serious degradation of the system performance, resistors are loaded at the edge of the antenna and then Tx and Rx UWB antennas are optimized by simulation in time domain. For images of targets buried under the ground migration technique is applied and influence of tough ground surface on distortion of received impulse signals is reduced using technique of noise and signal distortion reduction in time domain and its time resolution is enhanced. To verify the design optimization procedure, a prototype of an GPIR and an artificial test field are made. Measurement results show that the resolution of the system designed is as good as that of a theoretical model.

FEM-based Seismic Reliability Analysis of Real Structural Systems (실제 구조계의 유한요소법에 기초한 지진 신뢰성해석)

  • Huh Jung-Won;Haldar Achintya
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.19 no.2 s.72
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    • pp.171-185
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    • 2006
  • A sophisticated reliability analysis method is proposed to evaluate the reliability of real nonlinear complicated dynamic structural systems excited by short duration dynamic loadings like earthquake motions by intelligently integrating the response surface method, the finite element method, the first-order reliability method, and the iterative linear interpolation scheme. The method explicitly considers all major sources of nonlinearity and uncertainty in the load and resistance-related random variables. The unique feature of the technique is that the seismic loading is applied in the time domain, providing an alternative to the classical random vibration approach. The four-parameter Richard model is used to represent the flexibility of connections of real steel frames. Uncertainties in the Richard parameters are also incorporated in the algorithm. The laterally flexible steel frame is then reinforced with reinforced concrete shear walls. The stiffness degradation of shear walls after cracking is also considered. The applicability of the method to estimate the reliability of real structures is demonstrated by considering three examples; a laterally flexible steel frame with fully restrained connections, the same steel frame with partially restrained connections with different rigidities, and a steel frame reinforced with concrete shear walls.

Silk Fibroin and Substance P Combination Graft for the Reconstruction of a Bone Defect (실크 피브로인 지지체와 Substance P를 이용한 골 이식재)

  • Park, Ki-Yu;Choi, Kyo-Hee;Park, Young-Ju;Song, Ji-Young;Kim, Seong-Gon;Jo, You-Young;Kweon, Hae-Yong;Kang, Seok-Woo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.4
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    • pp.293-300
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    • 2011
  • Purpose: Substance P is a well known neurotransmitter and has been known to mediate pain. Recently, it has been unveiled that substance P is involved in the recruitment of mesenchymal stem cells to wound sites. The purpose of this study was to exam bone formation when a combination of substance P and silk fibroin was used in a bone defect model. Methods: Twenty rabbits were used and 40 calvarial defects were formed. They were divided as 4 groups (unfilled control, silk only, silk+$10{\mu}g$/ml substance P; Sub10, and silk+$100{\mu}g$/ml substance P; Sub100). All animals were humanely sacrificed 4 or 8 weeks after grafting. The specimens were analyzed by micro-computerized tomography and histological analysis. Results: When compared to the unfilled control to silk only group, there was significant difference in bone mineral density (BMD) and the attenuation coefficient (AC) at 4 weeks ($p$=0.037 and 0.038, respectively). When compared Sub10 group to Sub100 group, there was significant difference in BMD and AC at 8 weeks ($p$=0.004 for all). Residual graft amounts were $52.1{\pm}15.8$%, $15.2{\pm}9.2$% and $9.0{\pm}3.3$% for silk only, Sub10, and Sub100 groups, respectively. When comparing the residual graft amount of silk only to sub10 or sub100, the differences were statistically significant ($p$ <0.001). Conclusion: The silk fibroin scaffold showed higher BMD and AC than the unfilled control. The combination graft with substance P and silk fibroin scaffold showed a faster graft degradation than with a silk fibroin scaffold only.

3D Shape Embodiment of Dam using the 3D Laser Scanning System (3차원 레이저 스케닝 시스템을 이용한 댐체의 3차원 형상구현)

  • Shon, Ho-Woong;Yun, Bu-yeol;Park, Dong-il;Pyo, Ki-Won
    • Journal of the Korean Geophysical Society
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    • v.9 no.4
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    • pp.377-386
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    • 2006
  • There is an inseparable relation between human race and engineering work. As world developed into highly industrialized society, a diversity of large structures is being built up correspondently to limited topographical circumstance. Though large structures are national establishments which provide us with convenience of life, there are some disastrous possibilities which were never predicted such as ground subsidence and degradation. It is very difficult to analyze the volume of total metamorphosis with the relative displacement measurement system which is now used and it is impossible to know whether there is structural metamorphosis within a permissible range of design or not. In this research with an object of 13-year-old earthen dam, through generating point-cloud which has 3D spatial coordinates(x, y, z) of this dam by means of 3D Laser Scanning, we can get real configuration data of slanting surface of this dam with this method of getting a number of 3D spatial coordinates(x, y, z). It gives 3D spatial model to us and we can get various information of this dam such as the distance of slanting surface of dam, dimensions and cubic volume. It can be made full use of as important source material of reinforcement and maintenance works to detect previously the bulging of the dam through this research.

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New Synthesis of the Ternary Type Bi2WO6-GO-TiO2 Nanocomposites by the Hydrothermal Method for the Improvement of the Photo-catalytic Effect (개선된 광촉매 효과를 위한 수열법에 의한 삼원계 Bi2WO6-GO-TiO2 나노복합체의 쉬운 합성 방법)

  • Nguyen, Dinh Cung Tien;Cho, Kwang Youn;Oh, Won-Chun
    • Applied Chemistry for Engineering
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    • v.28 no.6
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    • pp.705-713
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    • 2017
  • A novel material, $Bi_2WO_6-GO-TiO_2$ composite, was successfully synthesized using a facile hydrothermal method. During the hydrothermal reaction, the loading of $Bi_2WO_6$ and $TiO_2$ nanoparticles onto graphene sheets was achieved. The obtained $Bi_2WO_{6-GO-TiO2}$ composite photo-catalysts were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray (EDX) analysis, transmission electron microscopy (TEM), Raman spectroscopy, ultraviolet-visible diffuse reflectance spectroscopy (UV-vis-DRS), and X-ray photoelectron spectroscopy (XPS). The $Bi_2WO_6$ nanoparticle showed an irregular dark-square block nanoplate shape, while $TiO_2$ nanoparticles covered the surface of the graphene sheets with a quantum dot size. The degradation of rhodamine B (RhB), methylene blue trihydrate (MB), and reactive black B (RBB) dyes in an aqueous solution with different initial amount of catalysts was observed by UV spectrophotometry after measuring the decrease in the concentration. As a result, the $Bi_2WO_6-GO-TiO_2$ composite showed good decolorization activity with MB solution under visible light. The $Bi_2WO_6-GO-TiO_2$ composite is expected to become a new potential material for decolorization activity. Photocatalytic reactions with different photocatalysts were explained by the Langmuir-Hinshelwood model and a band theory.

Matrix Metalloproteinase-2 -1306 C>T Gene Polymorphism is Associated with Reduced Risk of Cancer: a Meta-analysis

  • Haque, Shafiul;Akhter, Naseem;Lohani, Mohtashim;Ali, Arif;Mandal, Raju K.
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.889-896
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    • 2015
  • Matrix metalloproteinase-2 (MMP2) is an endopeptidase, mainly responsible for degradation of extracellular matrix components, which plays an important role in cancer disease. A single nucleotide polymorphism (SNP) at -1306 disrupts a Sp1-type promoter site. The results from the published studies on the association between MMP2 -1306 C>T polymorphism and cancer risk are contradictory and inconclusive. In the present study, a meta-analysis was therefore performed to evaluate the strength of any association between the MMP2 -1306 C>T polymorphism and risk of cancer. We searched all eligible studies published on association between MMP2 -1306 C>T polymorphism and cancer risk in PubMed (Medline), EMBASE and Google Scholar online web databases until December 2013. Genotype distribution data were collected to calculate the pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) to examine the strength of the association. A total of 8,590 cancer cases and 9,601 controls were included from twenty nine eligible case control studies. Overall pooled analysis suggested significantly reduced risk associated with heterozygous genotype (CT vs CC: OR=0.758, 95%CI=0.637 to 0.902, p=0.002) and dominant model (TT+CT vs CC: OR=0.816, 95%CI=0.678 to 0.982, p=0.032) genetic models. However, allelic (T vs C: OR=0.882, 95%CI=0.738 to 1.055, p=0.169), homozygous (TT vs CC: OR=1.185, 95%CI=0.825 to 1.700, p=0.358) and recessive (TT vs CC+CT: OR=1.268, 95%CI=0.897 to 1.793, p=0.179) models did not show any risk. No evidence of publication bias was detected during the analysis. The results of present meta-analysis suggest that the MMP2 -1306 C>T polymorphism is significantly associated with reduced risk of cancer. However, further studies with consideration of different populations will be required to evaluate this relationship in more detail.

Study of the Capsule Train Ride Comfort Improvement by using the Damping Control in Suspension System (현가장치 내 감쇠 제어를 이용한 캡슐트레인 승차감 향상 연구)

  • Lee, Jin-Ho;Lim, Jungyoul;You, Won-Hee;Lee, Kwansup
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.547-557
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    • 2020
  • In this study, damping control devices were applied to the suspension system of a capsule train, and the effects were investigated to improve the ride comfort. The superconductor electrodynamic suspension (SC-EDS) method is used for the capsule train levitation. This method has advantages such as no gap control and a large gap. However, the SC-EDS method has disadvantages such as large gap variation and small damping characteristics against outer vibration, which causes degradation of the ride comfort. In this study, the damping control devices in the primary and secondary suspension were considered to improve the ride comfort in the capsule train. Damping control devices in the primary and secondary suspension can reduce the vibration transmission from outer disturbances to the bogie and from the bogie to the car body, respectively. Simulations for dynamic characteristics analyses were conducted based on the capsule train dynamic model to investigate the effects of the damping control devices on the ride comfort. As a result, it was confirmed that the ride comfort requirements according to the ISO standard can be satisfied by applying the damping control in the capsule train suspension.