• Journal of Oriental Neuropsychiatry
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• v.30 no.1
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• pp.1-11
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• 2019

Objectives: Attention-Deficit/Hyperactivity Disorder (ADHD) is characterized by a persistent pattern of inattention and/or hyperactivity impulsivity that interferes with function or development in children. In traditional Korean medicine (TKM) and traditional Chinese medicine (TCM), ADHD is classified by several patterns based on symptoms and signs. However, currently, there is no objective diagnostic tool for ADHD in traditional medicine. The objective of this study was to develop the Pattern Identification Questionnaire for ADHD (parents-survey style) to be used in Korean medicine, through a literature review and consultation with groups of experts. Methods: The types of pattern identifications of ADHD mentioned in 13 pieces of Korean and Chinese literatures and their symptoms and signs were analyzed. The advisory committee (15 Neuropsychiatrist and 11 Pediatrist in Korean Medicine) assessed the appropriateness of the literature selection and the types of pattern identification selection and their symptoms and signs, and weighed the significance of the symptoms and signs. The Pattern Identification Questionnaire for ADHD was developed using the calculated weights by evaluated significance. The translation of symptoms and signs to the Korean language was achieved through consultation with expert translators. Results: 1. Four pattern identification types and their symptoms and signs were selected according to frequency of appearance in the Korean and Chinese literatures, and were reviewed by the advisory committee: Kidney yin deficiency and liver yang ascendant hyperactivity (腎虛肝亢), Dual deficiencies in the heart and spleen (心脾兩虛), Phlegm-fire harassing the heart (痰火擾心), and Spleen weakness and liver energy preponderance (脾虛肝旺). 2. The weights of all the symptoms and signs in the four patterns were calculated using the means and standard deviations of the symptoms and signs' importance that were obtained from specialists' significance weighting. 3. The Pattern Identification Questionnaire for ADHD (parents-survey style) in Korean medicine composed of 38 questions was suggested. Conclusions: Using a review of the literature and expert advice, Pattern Identification Questionnaire for ADHD (parents-survey style) in Korean medicine was developed. Further clinical study is required to develop a final version of the questionnaire through the evaluation of reliability and validity.

• Korean Journal of Clinical Laboratory Science
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• v.50 no.4
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• pp.399-405
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• 2018

The platelet count in clinical laboratories is essential for the diagnosis and treatment of hemostasis abnormalities, and accurate platelet counting in the low count range is of prime importance for deciding if a platelet transfusion is needed and for monitoring after chemotherapy. Quality control is designed to reduce and correct any deficiencies in the internal analytical process of a clinical laboratory prior to the release of patient results. Fragmented erythrocytes are the major confusing factors for platelet counting because of their similar size to platelets. The authors found that the low range QC values were out of 2SD with a Sysmex automatic analyzer in internal quality control process. Thus far, there has been little discussion on the relationship between hemolysis and the platelet parameters. Therefore, this study focused on the performance of automated platelet counts, including the PLT-F, the PLT-I, and PLT-O methods at the low platelet range using the low level QC materials and compared the 5 platelet parameters with the hemolyzed samples. The results showed that the CV was the smallest with PLT-F and P-LCR increased from 18.4 to 31.9% in the hemolysis samples. These results indicate that a more accurate estimation of the platelet counts can be achieved using the PLT-F method than the PLT-I method at the low platelet range. The use of the PLT-F system improves the confidence of results in low platelets samples in a routine hematology laboratory. The results suggest that P-LCR is a new parameter in assessing samples when the specimen is suspected of hemolysis and deterioration. Nevertheless, further studies will be needed to establish the relationship with P-LCR and hemolysis using human blood specimens.

• Korean Journal of Environmental Biology
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• v.36 no.4
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• pp.620-625
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• 2018

Pyropia yezoensis is one of the most extensively cultivated seaweeds used as food in Korea. However, the quality and yield of Pyropia farms are frequently affected by outbreaks of thallus discoloration. The objective of this study was to develop a simple and rapid method to evaluate P. yezoensis discoloration caused by nutrient deficiencies. A colorimeter was used to quantify the color of P. yezoensis in nutrient deficient media over 10 days. Quantitative values of lightness (L), redness (a), and yellowness (b) measured with a colorimeter were used as indicators of P. yezoensis discoloration. The vacuoles of P. yezoensis were observed at 4 days and swelled gradually from 6 days onward. The three colorimeter parameters L, a, and b values showed significantly different values with culture period. The lightness (L) value was darker initially, and continued to lighten over culture period. The yellowness (b) value increased, but the redness (a) value decreased throughout this study. The a/b ratio and redness (a) values from the colorimeter were important P. yezoensis color change indicators. The discoloration group of P. yezoensis had quantitative values for parameters of L above 70, a below 2.6, and b above 15.0. The results of this study showed that quantitative colorimetric measurements can be used as tools for simple and rapid detection of P. yezoensis discoloration.

• Journal of Korean Society of Archives and Records Management
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• v.19 no.3
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• pp.123-153
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• 2019

The study aims to develop and verify evaluation factors and items for assessing the quality when digitizing intangible cultural heritage record information resources. To derive evaluation areas and factors, the study analyzes the digitalization cases of the National Intangible Heritage Center and International Information and Networking Centre for Intangible Cultural Heritage in the Asia-Pacific region (ICHCAP) under the auspices of UNESCO, along with digitalization-related guidelines, National Archives of Korea standards, and previous studies. Afterward, to select the importance of evaluation factors and items developed, the study conducted a survey on working-level officials of intangible cultural heritage-related organizations and those working on digitalization, and established an allocation system based on the selected importance. Furthermore, the study performed a pilot evaluation by applying it to a digitalized intangible cultural heritage record information resources and conducted a focus group interview (FGI) to verify the results of the evaluation. Through the evaluation factors and items developed in this study, the agency can objectify the deficiencies of digitalization at a glance and use them as basic data by practitioners in the future.

• Convergence Security Journal
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• v.17 no.5
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• pp.63-69
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• 2017

In the early 1990s, IETF(Internet Engineering TaskForce) had started the discussion on new address protocol that can modify and supplement various drawbacks of existing IPv4 address protocol with the introduction of CIDR(Classless Inter-Domain Routing) which is a temporary solution for IPv4 address depletion, NAT, private IP address. While various standards related to new address protocol has been proposed, the SIPP(Simple Internet Protocol Plus) was adopted among them because it is regarded as the most promising solution. And this protocol has been developed into current IPv6. The new concepts are introduced with modifying a lot of deficiencies in the exisitng IPv4 such as real-time data processing, performance on QoS, security and the efficiency of routing. Since many security threats in IPv6 environment still exist, the necessity of stable data communication environment has been brought up continuously. This paper deveopled one-way communication algorithm in IPv6 based on the high possibility of protecting the system from uncertain and potential risk factors if the data is transmitted in one way. After the analysis of existing IPv6 and ICMPv6, this paper suggests one-way communication algorithm as a solution for existing IPv6 and ICMPv6 environment.

• Journal of Nutrition and Health
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• v.54 no.5
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• pp.425-434
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• 2021

The discovery of the relationship between nutrients and deficiency diseases during the 100 years from the mid-1800s to the mid-1900s was a breakthrough that led to advances in the study of nutrition. The Recommended Dietary Allowances (RDA) were created as a quantitative standard for avoiding diseases caused by nutrient deficiency. In addition, a reductionism paradigm has become generally accepted among nutrition scholars in health and disease, which focused on the properties of individual nutrients, content in foods, cellular levels, and mechanisms of action. The reductionist paradigm worked very well for the prevention and treatment of malnutrition diseases. However, as the incidence of nutrient deficiencies decreased and that of chronic diseases increased, the nutrition goals have been changed to secure safe and adequate nutrient intake and to reduce chronic disease risks. Accordingly, Dietary Reference Intakes (DRIs), a set of nutrient-based reference values, were designed to replace the RDA. The revised Korean DRIs were published for 40 nutrients in 2020. However, there is still room for improvement in the reference intake levels targeted at reducing the risk of chronic disease. The reductionist approach can no longer be practical because chronic diseases are related to the interactions between multi-components in the foods and multi-targets in the body. Therefore, a second innovative leap is needed following the nutrition development breakthrough made over 100 years ago. To this end, the nutrition paradigm must evolve from reductionism to a holism approach. Cutting-edge scientific technologies, such as metabolomics, transcriptomics, microbiomics, and bioinformatics, should also be acceptable in nutrition science based on the knowledge gained from basic nutrition studies.

• (The)Korea Educational Review
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• v.23 no.4
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• pp.101-133
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• 2017

This Study aims to evaluate teacher policy in the Park Administration and to suggest tasks based on the results. To attain the aim, it describes overall teacher policy process in Park Administration and evaluates teacher policy based on the criteria which was driven from the CIPP model. The conclusions are summarized as follows. First, the environmental suitability of the situation assessment was met in general. The reason for this was that the teacher policy of the Park Geun-hye government was introduced reflecting changes in the environment and demands of policy stakeholders. The validity and feasibility of the policy objective of the input evaluation were not satisfied. There were deficiencies in the objectives of the policy measures. The objectives of the measures were not linked to the policy objectives. The budget necessary for policy enforcement were not secured. In future policy design, efforts should be made to examine whether the policy goals are valid, to secure resources necessary for policy implementation and to increase the feasibility of policies. The procedural rationality of the process evaluation and the suitability of the means were not met. Discussion with the interest group was omitted, it was not clear whether the implementation of the policy was linked to the policy goal. In the future, it will be necessary to focus on procedures such as communication and collaboration with stakeholders, to make immediate revisions in case of problems. The effectiveness and satisfaction of the output evaluation were low. Because the validity of the policy objectives, the suitability of the means, and procedural rationality were not satisfied. In the future, it will be necessary to systematically design policies and communicate with stakeholders in the execution process to prevent policy failures and actively.

• (The) Korean Journal of Educational Psychology
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• v.32 no.3
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• pp.421-442
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• 2018

This study aimed to explore the constructs of the characteristics of at-risk learners with diverse educational needs in the blind spots of education, in order to understand them comprehensively and detect them early in schools. Participants were 156 elementary, middle, and high school teachers who filled out a semi-structured questionnaire consisting of open questions about their implicit knowledge of the characteristics of at-risk learners in the blind spots of education. Qualitative data were analyzed using a modified consensual qualitative research method. The main findings of this study are as follows. First, five domains and 16 categories were derived as the main constructs of the characteristics of learners in the blind spots of education. Second, the most listed of the five domains was the "domain of low learning and cognition," whereas the least listed domain was the "everyday life domain." Finally, deficiencies of interpersonal skills and interactive communications and categories related to family structure and functions frequently appeared among the 16 categories. Based on these results, implications and potentials for follow-up studies were further discussed.

• Development and Reproduction
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• v.25 no.1
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• pp.15-24
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• 2021

Benzo[a]pyrene (B[a]P) is a potent carcinogen and is classified as an endocrine-disrupting chemical. In mammalian testes, Sertoli cells support spermatogenesis. Therefore, if these cells are negatively affected by exposure to xenotoxic chemicals, spermatogenesis can be seriously disrupted. In this context, we evaluated whether mouse testicular TM4 Sertoli cells are susceptible to the induction of cytotoxicity-mediated cell death after exposure to B[a] P in vitro. In the present study, while B[a]P and B[a]P-7,8-diol were not able to induce cell death, exposure to BPDE resulted in cell death. BPDE-induced cell death is accompanied by the activation of caspase-3 and caspase-7. Depolarization of the mitochondrial membrane and cytochrome c release from mitochondria were observed in benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE)-treated cells. These results indicate that TM4 cells are susceptible to apoptosis in a caspase-dependent manner. Western blot and reverse transcription-polymerase chain reaction (RT-PCR) analyses showed that aryl hydrocarbon receptor (AhR) expression was almost undetectable in TM4 cells and that its expression was not altered after B[a]P treatment. This indicates that TM4 cells are nearly AhR-deficient. In TM4 cells, the CYP1A1 protein and its activity were not present. From these results, it is clear that AhR may be a prerequisite for CYP1A1 expression in TM4 cells. Therefore, TM4 cells can be referred to as CYP1A1-deficient cells. Thus, TM4 Sertoli cells are believed to have a rigid and protective cellular machinery against genotoxic agents. In conclusion, it is suggested that tolerance to B[a]P cytotoxicity is associated with insufficient AhR and CYP1A1 expression in testicular Sertoli cells.

• Smart Media Journal
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• v.10 no.1
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• pp.9-15
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• 2021

The eye tracking system designed in this paper is an eye-based computer input device designed to give an easy access for those who are uncomfortable with Lou Gehrig's or various muscle-related diseases. It is an eye-based-computer-using device for users whose potential demand alone amounts to 30,000. Combining the number of Lou Gehrig's patients in Korea estimated at around 1,700, and those who are unable to move their bodies due to various accidents or diseases. Because these eye input devices are intended for a small group of users, many types of commercial devices are available on the market. It is making them more expensive and difficult to use for these potential users, less accessible. For this reason, each individual's economic situation and individual experience with smart devices are slightly different. Therefore, making it difficult to access them in terms of cost or usability to use a commercial eye tracking system. Accordingly, attempts to improve accessibility to IT devices through low-cost but easy-to-use technologies are essential. Thus, this paper proposes a complementary superior performance eye tracking system that can be conveniently used by far more people and patients by improving the deficiencies of the existing system. Through voluntary VoCs(Voice of Customers) of users who have used different kinds of eye tracking systems that satisfies it through various usability tests, and we propose a reduced system that the amount of calculation to 1/15th, and eye-gaze tracking error rate to 0.5~1 degree under.