• Journal of the Korean Ceramic Society
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• v.38 no.3
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• pp.207-211
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• 2001

The effects of the sintering atmosphere and Ni content on t도 densification of TiB$_2$-Ni have been investigated. TiB$_2$powder compacts containing 10, 20, and 30 wt% Ni were liquid-phase sintered at 1500-1$700^{\circ}C$ in vacuum or in flowing Ar. The densification was enhanced as Ni content increased. For a given Ni content, the densification was faster in compacts in compacts with larger grain size. These densification behaviors agree well with the prediction of the recently developed pore-filling theory. For samples containing high Ni contents, 80TiB$_2$-20Ni and 70TiB$_2$-30Ni, the densification was faster in vacuum than in Ar. In particular, 70TiB$_2$-30Ni was fully densified at 1$700^{\circ}C$ for 60min in vacuum. The suppressed densification in Ar was due to the entrapped Ar in the isolated pores. On the other hand, for 90TiB$_2$-10Ni, the Ar-sintering resulted in higher densification than did the vacuum-sintering. This result was attributed to the suppression of Ni volatilization by the Ar in the furnace and a retarded isolation of pores due to the limited amount of liquid in the sample. Therefore, vacuum sintering is recommended for the preparation of TiB$_2$-Ni with a high Ni content while Ar sintering is recommended for the preparation of TiB$_2$-Ni with a low Ni content.

• Journal of Korean Medical classics
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• v.22 no.2
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• pp.327-336
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• 2009

Ogyeom(吳謙) was a famous doctor in the early Cheong(淸) dynasty. The year of birth and death is unknown. He was a chief(院判) of the Taeuiwon(太醫院) in the early Cheong(淸) dynasty 1732-1759. He wrote "Uijonggeumgam(醫宗金鑒)" which was famous at the time as well, Thus it was used in the medical curriculum during the Cheong(淸) dynasty. "Jeongjeongjunggyeongjeon seo(訂正仲景全書)" is a part of "Uijonggeumgam(醫宗金鑒)", including the past comments, annotations and Ogyeom(吳謙)'s annotations, corrections of "Sang-hanron(傷寒論)", "Geumgwe yoryak(金匱要略)". This article translated the text associated with Gyejitang(桂枝湯) in "Jeongjeongjoonggyeongjeonseo(訂正仲景全書)". The main content is as shown below. First, In the opinion of Ogyeom(吳謙), Yangbu-eumyak(陽浮陰弱) should be understood as that Gi(氣) is upward in the defense aspect(衛分), and weak in the nutrient aspect(營分). Second, how to take Gyejitang(桂技揚) is very important, He states correct ways of intaking Gyejitang(桂技揚). Third, Gyejitang(桂技揚) has a different sweating mechanism from that of Mahwangtang(麻黃湯). Gyejitang(桂技揚) promotes the defense Gi(衛氣), thus, spreading out the healthy Gi(正氣) well.

• BMB Reports
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• v.34 no.1
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• pp.15-20
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• 2001

One of the innate immune reactions in invertebrates is the pro-phenoloxidase (pro-PO) activation system that is involved in the generation of superoxide, melanin synthesis, and the subsequent sequestration of foreign matter entering the hemocoel of the invertebrates. However, the molecular mechanism of this biological reaction is still obscure. To expand our understanding of the biological roles of the pro-PO activation system in invertebrates, we performed a yeast two-hybrid screening by using three regions of pro-PO as bait and a yeast two-hybrid cDNA library from Tenebrio molitor larvae as prey We isolated a novel partial cDNA clone that encodes a glycine-rich protein that interacted with the active phenoloxidase (termed phenoloxidase interacting protein, POIP). POIP consists of two domains: One is an N-terminal unique domain and the other is a C-terminal glycine-rich domain. The C-terminal glycine-rich domain showed sequential homology with those of insect antifungal proteins. Also, the yeast two-hybrid screen in a reverse orientation (using POIP as bait) yielded PO, suggesting that the PO-POIP interaction is specific. By using a 315 bP PCR fragment of the N-terminal unique region of POIP, we cloned the full-length cDNA of POIP from the Tenebruo cDNA library constructed by using E. coli injected larvae. The interaction analysis between PO, and a truncated fragment lacking the N-terminal unique region of POIP, indicated that the N-terminal unique region is necessary for interaction between PO and POIP. The expression level of the POIP mRNA is increased by bacterial injection into T. molitor larvae. This suggests that POIP might be engaged in the humoral defense reaction.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.42 no.7
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• pp.594-600
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• 2014

In modern warfare, securing communication channel by combatting opponents' electromagnetic attack is a crucial factor to win the war. Military satellite digital transponder is a communication payload of the next generation military satellite that maintains warfare networks operational in the presence of interfering signals by securely relaying signals between ground terminals. The transponder in this paper is classified as a partial processing transponder which performs cost effective secure relaying in satellite communication links. The control functions of transmission security achieve immunity to hostile interferences which may cause malicious effects on the link. In this paper, we present an efficient architecture for implementing the control mechanism. Two major ideas of pipelined processing in per-group control and software processing of blocked band information dramatically reduce the complexity of the hardware. A control code sequence showing its randomness with uniform distribution is exemplified and qualification test results are briefly presented.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.48 no.7
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• pp.523-528
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• 2020

A lateral type MEMS inertial switch was designed on the same principle as spring-mass system. The MEMS switch is used for arming mechanism of the arm-fire device by sensing the applied acceleration. We analyzed the switching capability of the MEMS switch under various acceleration conditions via performance model. Simulation results showed that the MEMS switch works very well at 10 g when the applied acceleration slope does not exceed 10 g/msec. On the other hand, the threshold operating acceleration level simulation exceeded the requirement (10±2 g) due to the width and length of the spring by considering 10% tolerance of the design values. Design modification of doubling the width of the spring, which is difficult to reduce less than 10% tolerance in fabrication process, was proposed after confirming the simulation results comply the requirement.

• Journal of Microbiology and Biotechnology
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• v.25 no.2
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• pp.255-267
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• 2015

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic debilitating disease affecting ruminants worldwide. In the present study, we aimed to determine the major gene networks and pathways underlying the immune response to MAP infection using whole-blood cells, as well as provide the potential transcriptional markers for identifying the status of MAP infection. We analyzed the transcriptional profiles of whole-blood cells of cattle identified and grouped according to the presence of MAP-specific antibodies and the MAP shed by them. The grouping was based on the results obtained by ELISA and PCR analyses as follows: i) Test1 group: MAP-negative results obtained by ELISA and positive results obtained by PCR; ii) Test2 group: MAP-positive results obtained by ELISA and negative results obtained by PCR; iii) Test3 group: MAP-positive results obtained by ELISA and positive results obtained by PCR; iv) uninfected control: MAP-negative results obtained both by ELISA and PCR analysis. The results showed down-regulated production and metabolism of reactive oxygen species in the Test1 group, activation of pathways related to the host-defense response against MAP (LXR/RXR activation and complement system) in the Test2 and Test3 groups, and anti-inflammatory response (activation of IL-10 signaling pathway) only in the Test3 group. Our data indicate a balanced response that serves the immune-limiting mechanism while the host-defense responses are progressing.

• Mycobiology
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• v.33 no.3
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• pp.131-136
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• 2005

Infection structures were observed at the penetration sites on the leaves of cucumber plants inoculated with Colletotrichum orbiculare using a fluorescence microscope. The cucumber plants were previously drenched with suspension of bacterial strains Pseudomonas putida or Micrococcus luteus. The plants pre-inoculated with both bacterial strains were resistant against anthracnose after inoculation with C. orbiculare. To investigate the resistance mechanism by both bacterial strains, the surface of infected leaves was observed at the different time after challenge inoculation. At 3 days after inoculation there were no differences in the germination and appressorium formation of conidia of C. orbiculare as well as in the callose formation of the plants between both bacteria pre-inoculated and non-treated. At 5 days, the germination and appressorium formation of the fungal conidia were, however, significantly decreased on the leaves of plants pre-inoculated with M. luteus at the concentration with $1.0{\times}10^7\;cfu/ml$. Furthermore, callose formation of plants cells at the penetration sites was apparently increased. In contrast, there were no defense reactions of the plants at the concentration with $1.0{\times}10^6\;cfu/ml$ of M. luteus. Similarly, inoculation P. putida caused no plant resistance at the low concentration, whereas increase of callose formation was observed at the higher concentration. The results of this study suggest that the resistant mechanisms might be differently expressed by the concentration of pre-treatment with bacterial suspension.

• Korean Chemical Engineering Research
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• v.52 no.3
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• pp.360-365
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• 2014

Vapor-phase hydrogen peroxide(VPHP) has been used as a sterilant in the field of medical and pharmaceutical application due to low corrosive than chlorine contained sterilant. In addition, it is well known that VPHP is effective for decontamination of chemical warfare agents by adding ammonia gas. In this study, the decontamination efficiency was confirmed about CEPS, DFP and dimethoate as simulants of HD, GD and VX using VPHP respectively. For this purpose, VPHP generated from self configured device was injected into decontamination chamber and maintained for reaction time. After the decontamination, the residues are analyzed by GC/MS and decontamination efficiency was calculated. Through by-product for each simulants, the similarities in reaction mechanism of chemical warfare agents were confirmed. CEPS was completely decontaminated at 30% relative humidity within 60 min. By adding ammonia gas, DFP and dimethoate were completely decontaminated within 30 and 150 min respectively.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.11
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• pp.1135-1141
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• 2014

Performing wideband DDC while quantizing signal over a wide dynamic range and high speed sampling rate have primarily been implemented in a hardware such as, FPGA or ASIC because of time-consuming job. Real-time wideband DDC SW, even though signal environment changes, adapt to signal environment flexibly and can be reused. In addition, it has a lower price than the hardware implementation. In this paper, we study the system design that can be stored in real time designing a high-speed parallel processing architecture for SW-based wideband DDC. Finally, applying a Ping-Pong Buffering mechanism for receiving a signal in real time and CUDA for a high-speed signal processing, we verify wideband DDC design procedure that meets the signal processing.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.2
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• pp.11-17
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• 2016

Powder metallurgy nickel based superalloy has been used in a high temperature part of turbine engine for airplane. The fatigue crack growth behavior was investigated using CT specimens for the materials at room temperature(R.T.), $600^{\circ}C$ and $700^{\circ}C$. The direct current potential drop(DCPD) method suggested by ASTM E647 was used to measure the crack length during fatigue crack growth at various stress ratios. The fatigue crack growth rate at R=0.5 was faster than that at R=0.1 for all temperature conditions and increased with the increase of stress ratio and temperature. Fractography was conducted for analysis of fracture mechanism.