• The Plant Pathology Journal
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• 제21권1호
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• pp.47-54
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• 2005

Identification of host genes involved in disease progresses and/or defense responses is one of the most critical steps leading to the elucidation of disease resistance mechanisms in plants. Soybean mosaic virus (SMV) is one of the most prevalent pathogen of soybean (Glycine max). Although the soybeans are placed one of many important crops, relatively little is known about defense mechanism. In order to obtain host genes involved in SMV disease progress and host defense especially for virus resistance, two different cloning strategies (DD RT-PCR and Subtractive hybridization) were employed to identify pathogenesis- and defenserelated genes (PRs and DRs) from susceptible (Geumjeong 1) and resistant (Geumjeong 2) cultivars against SMV strain G7H. Using these approaches, we obtained 570 genes that expressed differentially during SMV infection processes. Based upon sequence analyses, differentially expressed host genes were classified into five groups, i.e. metabolism, genetic information processing, environmental information processing, cellular processes and unclassified group. A total of 11 differentially expressed genes including protein kinase, transcription factor, other potential signaling components and resistant-like gene involved in host defense response were selected to further characterize and determine expression profiles of each selected gene. Functional characterization of these genes will likely facilitate the elucidation of defense signal transduction and biological function in SMV-infected soybean plants.

• 한국군사과학기술학회지
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• 제25권1호
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• pp.30-44
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• 2022

The advent of deep learning-based algorithms has facilitated researches on target detection from synthetic aperture radar(SAR) imagery. While most of them concentrate on detection tasks for ships with open SAR ship datasets and for aircraft from SAR scenes of airports, there is relatively scarce researches on the detection of SAR ground vehicle targets where several adverse factors such as high false alarm rates, low signal-to-clutter ratios, and multiple targets in close proximity are predicted to degrade the performances. In this paper, a dataset of ground vehicle targets acquired from TerraSAR-X(TSX) satellite SAR images is presented. Then, both detection and instance segmentation are simultaneously carried out on this dataset based on the deep learning-based Mask R-CNN. Finally, this paper shows the future research directions to further improve the performances of detecting the SAR ground vehicle targets.

• 한국군사과학기술학회지
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• 제26권1호
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• pp.102-112
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• 2023

This research mainly focuses on the transport and dispersion of chemical agent plume according to the Lagrangian Puff Model and Lagrangian Particle Model of NBC_RAMS(Nuclear, Biological, Chemical Reporting And Modeling S/W System). NBC_RAMS was developed with the purposes of estimating the fate of Chemical, Biological, and Radioactive(CBR) agent plumes and evaluating damages in the Republic of Korea. First, it calculates the local weather pattern, i.e. wind speed, wind direction, and temperature, by considering the effects of land uses and topography. The plume behaviors are calculated by adopting the Lagrangian Puff Model(LPFM) or Lagrangian Particle Model(LPTM). In this research, we assumed a virtual chemical agent exposure event in a stable atmospheric condition during the summer season. The plume behaviors were estimated by both LPFM and LPTM on the used area(urbanized and dry area) and the agricultural land. The higher heat flux in the used area led to stronger winds and further downward movement moving of the chemical agent than the farmland. The lateral dispersion of the chemical plume was emphasized in the Lagrangian Puff Model because it adopted Gaussian distribution.

• 한국발생생물학회지:발생과생식
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• 제17권4호
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• pp.321-327
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• 2013

The innate immune system is the only defense weapon that invertebrates have, and it is the fundamental defense mechanism for fish. The innate immune response is important in newly hatched flounders because it is closely involved in the initial feeding phase, which is why it is essential for survival during the juvenile period. The expression analysis of genes involved in the innate immune response in the olive flounder (Paralichthys olivaceus) in the days after hatching is incomplete. Therefore, we have begun to examine the expression patterns of genes specifically induced during the development of the innate immune system in newly hatched flounders. Microscopic observation showed that pronephron formation corresponded with the expression of perforin-encoding gene. These results suggest that perforin plays a vital role in the innate immunity of the kidney during developmental stages. Perforin expression was strong at the start of the development of the innate immune response, and continued throughout all the development stages. Our findings have important implications with respect to perforin's biological role and the evolution of the first defense mechanisms in olive flounder. Further studies are required to elucidate the perforin-mediated innate immunity response and to decipher the functional role of perforin in developmental stages.

• Journal of Ginseng Research
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• 제35권1호
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• pp.1-11
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• 2011

Korean ginseng is a medicinally important perennial herb from the family Araliaceae. It has been cultivated for its highly valued medicinal properties for over 1,000 years in east Asian countries such as China, Korea, and Japan. Due to its longtime cultivation in shady areas, ginseng is frequently exposed to pathogenic infections. Plants protect themselves from microbial pathogens using an array of defense mechanisms, some of which are constitutively active, while others are activated upon pathogen invasion. These induced defense responses, controlled by defense-related genes, require tradeoffs in terms of plant fitness. We hypothesize that ginseng, as with other plants, possesses regulatory mechanisms that coordinate the activation of attacker-specific defenses in order to minimize fitness costs while attaining optimal resistance. Several classes of defense-related genes are induced by infection, wounds, irradiation, and other abiotic stresses. Both salicylates and jasmonates have been shown to cause such responses, although their specific roles and interactions in signaling and development are not fully understood in ginseng. This review summarizes possible defense-related genes in ginseng based on their expression patterns against biotic and abiotic stresses and describes their functional roles.

• 한국군사과학기술학회지
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• 제25권6호
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• pp.637-647
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• 2022

Since the concept of Manned-UnManned Teaming(MUM-T) and Unmanned Aircraft System(UAS) can efficiently respond to rapidly changing battle space, many studies are being conducted as key components of the mosaic warfare environment. In this paper, we propose a rule-based AI engagement model based on Basic Fighter Maneuver(BFM) capable of Within-Visual-Range(WVR) air-to-air combat and a simulation environment in which human pilots can participate. In order to develop a rule-based AI engagement model that can pilot a fighter with a 6-DOF dynamics model, tactical manuals and human pilot experience were configured as knowledge specifications and modeled as a behavior tree structure. Based on this, we improved the shortcomings of existing air combat models. The proposed model not only showed a 100 % winning rate in engagement with human pilots, but also visualized decision-making processes such as tactical situations and maneuvering behaviors in real time. We expect that the results of this research will serve as a basis for development of various AI-based engagement models and simulators for human pilot training and embedded software test platform for fighter.

• 한국IT서비스학회지
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• 제11권sup호
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• pp.17-26
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• 2012

Information technology convergence has been recognized one of the key drivers in the industry perspective. Korea government established IT convergence policy in 2008 and has been implementing it to the core industry such as automotive, shipbuilding and defense industries. This research analyzes various IT convergence issues based on an operation of defense IT convergence center, one of the industry IT convergence centers. Defense IT convergence issues are as follows : the methods for introducing rapid changing IT to military area, rapid deployment procedures of verified commercial technologies and products, regulations for using of domestic software promotion and so on. We define the concept of defense IT convergence and propose the framework and processes for applying IT to our defense sector as one of industries. Also, we establish various business models in the military perspective using defense IT convergence framework. In this paper, we focus the development of defense IT convergence through the alignment of national IT convergence policy and propose various business models established through operating a defense IT convergence center.

• Molecules and Cells
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• 제25권3호
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• pp.323-331
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• 2008

Plants are continually exposed to a variety of potentially pathogenic microbes, and the interactions between plants and pathogenic invaders determine the outcome, disease or disease resistance. To defend themselves, plants have developed a sophisticated immune system. Unlike animals, however, they do not have specialized immune cells and, thus all plant cells appear to have the innate ability to recognize pathogens and turn on an appropriate defense response. Using genetic, genomic and biochemical methods, tremendous advances have been made in understanding how plants recognize pathogens and mount effective defenses. The primary immune response is induced by microbe-associated molecular patterns (MAMPs). MAMP receptors recognize the presence of probable pathogens and evoke defense. In the co-evolution of plant-microbe interactions, pathogens gained the ability to make and deliver effector proteins to suppress MAMP-induced defense responses. In response to effector proteins, plants acquired R-proteins to directly or indirectly monitor the presence of effector proteins and activate an effective defense response. In this review we will describe and discuss the plant immune responses induced by two types of elicitors, PAMPs and effector proteins.

• Biomolecules & Therapeutics
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• 제22권6호
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• pp.497-502
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• 2014

In the present study, we found that the natural compound arctigenin inhibited hydrogen peroxide-induced reactive oxygen species (ROS) production in rat primary astrocytes. Since hemeoxygenase-1 (HO-1) plays a critical role as an antioxidant defense factor in the brain, we examined the effect of arctigenin on HO-1 expression in rat primary astrocytes. We found that arctigenin increased HO-1 mRNA and protein levels. Arctigenin also increases the nuclear translocation and DNA binding of Nrf2/c-Jun to the antioxidant response element (ARE) on HO-1 promoter. In addition, arctigenin increased ARE-mediated transcriptional activities in rat primary astrocytes. Further mechanistic studies revealed that arctigenin increased the phosphorylation of AKT, a downstream substrate of phosphatidylinositol 3-kinase (PI3K). Treatment of cells with a PI3K-specific inhibitor, LY294002, suppressed the HO-1 expression, Nrf2 DNA binding and ARE-mediated transcriptional activities in arctigenin-treated astrocyte cells. The results collectively suggest that PI3K/AKT signaling pathway is at least partly involved in HO-1 expression by arctigenin via modulation of Nrf2/ARE axis in rat primary astrocytes.

• 대한원격탐사학회지
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• 제21권6호
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• pp.483-491
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• 2005

SAR 기술은 일반 레이더 분야와는 달리 영상을 제작해야 하므로 각종 신호처리 기술들이 필요하다. 이러한 기술들은 선진국에서 기술이전을 회피하는 분야로써 향후 항공기, 위성 및 무인기 SAR 체계를 국내 개발함에 있어 반드시 확보해야 할 분야이다. 본 연구에서는 SAR 영상 제작과 관련된 핵심기술들을 연구하고 실제로 활용도가 높은 상용 SAR 위성인 Radarsat을 대상으로 ASPR(ADD SAR Processor for Radarsat)을 자체 개발하고 성능을 검증해 봄으로써 향후 운용될 각종 SAR 체계에 필요한 영상제작 기술을 확보하고 국내개발 가능성을 검토해 본다. 개발된 ASPR의 성능비교를 위해 선진국 SAR 전문 업체인 MDA 및 Vexcel사에서 개발한 SAR Processor를 이용하여 비교 영상을 제작하였다.