PURPOSE. The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans. Materials and methods: This study used tablet-type denture cleansers, PolidentⓇ, CoolingdentⓇ and FittydentⓇ, along with liquid denture cleansers, HexamedineⓇ, ListerineⓇ and Apple vinegarⓇ. The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers. Results. In the 0.5 × 106 cfu/㎖ culture medium, the C. albicans' death rate of PolidentⓇ was significantly lower than those of FittydentⓇ, HexamedineⓇ, ListerineⓇ, and Apple vinegarⓇ(P<.05). In the 0.5 × 107 cfu/, the C. albicans' death rates of PolidentⓇ and CoolingdentⓇ were significantly lower than those of FittydentⓇ, HexamedineⓇ, ListerineⓇ and Apple vinegarⓇ(P<.05). The C. albicans' death rates of PolidentⓇ and CoolingdentⓇ were significantly decreased at 0.02 g and 0.01 g. The C. albicans' death rate of FittydentⓇ was significantly decreased at 0.005 g (P<.05). The C. albicans' death rate of HexamedineⓇ was significantly decreased at 1/16 dilution. The C. albicans' death rate of ListerineⓇ was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegarⓇ was decreased at 1/4 dilution (P<.05). Conclusion. As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.
Objective : Health insurers and policy makers are increasingly examining the hospital mortality rate as an indicator of hospital quality and performance. To be meaningful, a risk-adjustment of the death rates must be implemented. This study reviewed 5 severity measurement methods and applied them to the same data set to determine whether judgments regarding the severity-adjusted hospital mortality rates were sensitive to the specific severity measure. Methods : The medical records of 584 patients who underwent coronary artery bypass graft surgery in 6 general hospitals during 1996 and 1997 were reviewed by trained nurses. The MedisGroups, Disease Staging, Computerized Severity Index, APACHE III and KDRG were used to quantify severity of the patients. The predictive probability of death was calculated for each patient in the sample from a multivariate logistic regression model including the severity score, age and sex to evaluate the hospitals' performance, the ratio of the observed number of deaths to the expected number for each hospital was calculated. Results : The overall in-hospital mortality rate was 7.0%, ranging from 2.7% to 15.7% depending on the particular hospital. After the severity adjustment, the mortality rates for each hospital showed little difference according to the severity measure. The 5 severity measurement methods varied in their statistical performance. All had a higher c statistic and $R^2$ than the model containing only age and sex. There was a little difference in the relative hospital performance evaluation by the severity measure. Conclusion : These results suggest that judgments regarding a hospital's performance based on severity adjusted mortality can be sensitive to the severity measurement method. Although the 5 severity measures regarding hospital performance concurred, more often than would be expected by chance, the assessment of an individual hospital mortality rates varied by the different severity measurement method used.
The purpose of this study is to analyze death injuries and operation troubles of urban transit. No difference was shown in death rates between Line 1 of Pusan urban transit and Line 5, 7, And 8 of Seoul metropolitan transit. And relief time by another train did not depend upon the number of crews. We concluded that thorough inspection and preventive maintenance of trains and facilities are necessary for safe and timely service of urban transit.
Life table of Korean population for years 1983 1985 1987 and 1989 were constructed byt the National Bureau of Statics. The ago specific death rates were calculated froom the death registral ion for numerators and the estimated population by age and sex for denominators. In the course of constructing life tables, we have maole some adjustments for deficiencies in regist rat ion olata as follows. First, the non-registered portion oof infant deaths especially for neo-natal deaths was estirnateol and added too the original data. The main reason is that deaths occorring in the neo-natal period and prior to the registrat ion of birth leave little incentive for the registration of either the birth or the death. Second. t he do~hayed p(ortioon of deaths registering after one year of occurrence was estimated and added too the original data. Third t the ptortioon haying in, occuracies in ,~oge reporting was also estimated. Fourth the moving average methood was finally employed in an effort too remove the random error. The major fin(hings are as foolloows. 1. the average life expectancy at birth in 1989 is calculateol as 70.8 years in 1989, 2. a gap netween the male and female life expectancies is widened to more than 8 years toorm 1.8 years in 1906 10. It means that the female life expectancy has increased substantially, 3. the death rates of the middle - aged men starting age 40 are found to he relatively higher than those of females and younger age groups. This peculiar pattern was also found with the comparison of those of other countries.
The Journal of the Korean life insurance medical association
/
v.1
no.1
/
pp.88-95
/
1984
In Korea, life insurance policies are sold to the policy holders by insuring either the insureds undergo a medical examination at a clinic or the insureds' report their history of diseases ever experienced that replaces the medical examination. This study aimed to measure the level of death rates for the insureds between those who received medical examination and those who did not receive medical examination, and to examine differences of the rates in terms of the insureds' characteristics such as age, sex, cause of death and duration. A total number of 32,358 insureds were selected for the population of this study from the D. Life Insurance Company located in Seoul City. Out of the 32,358 insureds, 2,997 received medical examination and the rest of 29,381 did not received any medical examination. Results of analysis are summarized as follows: 1. Death rate per 100,000 insureds for the all was 19.3 in the first year, 96.3 in the second year, 143.8 in the third year 93.4 in the fourth year. For the group of medical examination received, the rate was zero in the first year, 41.3 in the second year, 55.4 in the third year and 268.8 in the fourth year, and for the group of non-medically examined the rate was 21.3 in the first year, 101.9 in the second year, 152.2 in the third year and 76.8 in the fourth year. The levels of death rates between the insureds with medical examsination and the inureds without medical examination were non-significant in the differences by duration except the levels of the third year, which indicated the death rate of non-medically examined group was higher than that of the medically examined group. 2. 73.0 per cent of the total deaths observed during the insured period were caused by various diseases and the rest of 27.0 per cent deaths were due to accidents. For the group of medical examination received, 55.6 per cent deaths were caused by diseases, and for the group of nonmedically examined, 74.7 per cent of deaths were due to diseases. 3. cancer was the most frequent cause which accounted for 22.0 per cent of the total deaths. Proportion of deaths due to cancer from the group of medical examination received was 22.2 per cent, and the corresponding rate for the group of non-medically examined also showed high rate of 22.0 per cent.
Korea National Statistical Office(KNSO) estimated period birth rates, period death rates, and probability of dying for infant(q$q_{0}$) at period life table, considering the unregistered infant deaths. As Ministry of Health and Welfare(MHW) conducted 1993 and 1996 birth cohort infant death surveys. KNSO re-estimated infant mortality levels(especially q$q_{0}$). For the re-estimation, reference data were derived from death registration. MHW surveys, death registration of developed countries. Model Life Tables, and Life Table for Japan. Seventeen simulations were made by the combination of estimation methods and reference data. The final $q_{0}$ was estimated based on the relationship between $q_{0}$ of MHW 1993 survey and $q_{1-4}$ of registered deaths for the period of 1971~1997. For 1993, $q_{0}$ was calculated directly from the 1993 MHW survey and interpolation and extrapolation were made for 1995 and 1997 using the relative decrease rates of $q_{0}$ between 1993 and 1996 MHW surveys. Utilizing the formular of Coale-Demeny North Model, $q_{0}$ was transformed into $m_{0}$ for the period 1971~1997. Finally, cremation data are found to be very useful for the estimation of 1998 infant mortality level by supplementing unregistered infant deaths, especially neonatal deaths. Furthermore, they are found to be very useful to produce fetal and perinatal death statistics.
Seo, Myoung-Won;Woo, Hyo-Jin;Lee, Gil-Seong;Choo, Yeon-Sik;Lee, Ki-Sup;Choi, Kee-Ryong;Park, Yong-Mok
Journal of Ecology and Environment
/
v.31
no.4
/
pp.333-339
/
2008
We investigated death rates, growth rates and recruitment of culms in two neighboring bamboo (Phyllostachys bamboosoides) stands nested in by two different bird species to analyze stand structure and to design conservation strategies. A third bamboo grove not used by birds, the Taewha stand, was included as a control stand. The bamboo stand occupied by birds in the family Ardeidae (the Ardeidae stand) had an approximately 1.5 times higher culm density than the stand occupied by birds in the family Corvidae (the Corvidae stand). The crude death rate and the number of newly emerged shoots were also higher in the Ardeidae stand than the Corvidae stand. The death rate for bamboo in the Ardeidae stand was not dependent on diameter at breast height (DBH) and was almost 40% for culms of all sizes, whereas most dead culms in the Corvidae stand were < 4 cm DBH. Consequently, we conclude that in the Ardeidae stand, density-independent causes of death are operating, while density-dependent factor are more important in the Corvidae site. The results of soil analysis in these stands suggest that the density-independent death pattern observed in the Ardeidae stand may be due to soil acidification resulting from wastes produced by the birds during breeding. On the other hand, the culm distribution and death patterns in the Corvidae stand suggest that the stand characteristics were not affected by the nesting birds. These results suggest that different conservation strategies must be applied to conserve bamboo groves used by ardeids and corvids for nesting.
Problems concerning the vital registration system and its management, errors and methods to adjust them in the vital registration data in Korea have been studied. It is found that birth and death registration rates were above 95% in 1994. The registration rates rose rapidly since 1970 due to 1) simplification of registration form, 2) improving accessibility by allowing registration at the current residence, 3) enforcing fine against non-registration, and 4) improvements in social security system. However, there should be some continuing efforts for further improvement of the vital registration system. The content error in the data could be substantially reduced following the rapid rise of the registration rates in the 1980s, though this has never been actually studied. There are still substantial registrations with false date of death. The false date of events may affect the computed vital rates specially when the registration rates are rapidly rising. Especially the death rates of the young can be seriously affected. A study on the data in the 1970s shows that death of age between 3 to 19 has been over-registered up to 67% compared with the expected. It is a serious matter that some researchers analyze the registration data without adjusting the errors. It is strongly recommended for the Government Statistical Office to undertake a study on the registration behavior of the people.
Cecen, Emre;Altun, Zekiye;Ercetin, Pinar;Aktas, Safiye;Olgun, Nur
Asian Pacific Journal of Cancer Prevention
/
v.15
no.21
/
pp.9445-9451
/
2014
Neuroblastoma is the most common extracranial solid tumor in children. Approximately half of the affected patients are diagnosed with high-risk poor prognosis disease, and novel therapies are needed. Sanguinarine is a benzophenanthridine alkaloid which has anti-microbial, anti-oxidant and anti-inflammatory properties. The aim of this study is whether sanguinarine has in vitro apoptotic effects and which apoptotic genes might be affected in the human neuroblastoma cell lines SH-SY5Y (N-myc negative), Kelly (N-myc positive, ALK positive), and SK-N-BE(2). Cell viability was analysed with WST-1 and apoptotic cell death rates were determined using TUNEL. After RNA isolation and cDNA conversion, expression of 84 custom array genes of apoptosis was determined. Sanguinarine caused cell death in a dose dependent manner in all neuroblastoma cell lines except SK-N-BE(2) with rates of 18% in SH-SY5Y and 21% in Kelly human neuroblastoma cells. Cisplatin caused similar apoptotic cell death rates of 16% in SH-SY5Y and 23% in Kelly cells and sanguinarine-cisplatin combinations caused the same rates (18% and 20%). Sanguinarine treatment did not affect apoptototic gene expression but decreased levels of anti-apoptotic genes NOL3 and BCL2L2 in SH-SY5Y cells. Caspase and TNF related gene expression was affected by the sanguinarine-cisplatin combination in SH-SY5Y cells. The expression of regulation of apoptotic genes were increased with sanguinarine treatment in Kelly cells. From these results, we conclude that sanguinarine is a candidate agent against neuroblastoma.
Park, Jung-Han;Lee, Young-Sook;Rhee, Jung-Ae;Cho, Hyun;Chung, Young-Hae;Park, Soon-Woo;Jun, Hae-Ri
Health Policy and Management
/
v.8
no.2
/
pp.125-148
/
1998
Accurate vital statistics are essential for a national health planning and evaluation. Among various vital statistics, birth and death rates, and infant and matemal mortality rates together with the causes of death are the very basic ones for above purposes as well as for the maternal and child health management. These statistics are based on the birth and death reports. It is required by law to report every birth and death within one month after its occurrence. However, in case of a neonatal death occurring prior to the birth report, most of the birth and death are not reported. Thus accurate infant and maternal mortality rates are not available yet in Korea. The main objective of this study is to develop a birth and infant death reporting system via computer network. We designed a new birth report form based on the current form and data from the analysis of medical record forms of 14 hospitals. A new form is basically addition of essential medical information to the current birth report form. Since a revision of the rules and regulations related wtih the birth report is necessary to use a new form, we kept the current from intact to make it acceptable to the government office for a field trial. We also developed computer programs for data input for birth and death reports at a medical faciltiy, data processing for production of maternal and child health indices at a health center, and management of maternal and child health services including immunization and postantal care at health center. The birth certificate and birth report can be printed out at a medical facility. The computer packages were programmed by Borland Delphi 3.0 and can be run under Windows 95 system. We proposed a new birth and death reporting system via computer network after a field trial for data input, transmission, and processing. The medical and demographic data o birth and death at medical facilities will be sent to health centers directly via computer network. The health center will retain the medical data for analysis and forward only the data for birth and death reports required by current regulations to the Dong, Up, or Myun Office. Once the birth or death is reported via computer network to the Dong Office, then the Dong Office will notify the baby's mother of the birth report and request to submit the baby's name by mail. When the baby's name its submitted. the Dong Office will forward the birth reports to the Common Court and Statistics Agency in the same way as the current system, Upon the completion of birth registration of the Common Court, the court will issue the birth certificate to mother which will be used in lieu of the family record. The advantages of proposed birth and death reporting system via computer network ar as follows ; I) The accuracy, timing, and completeness of reporting will be improved and more accurate maternal and child health indices can be obtained, ii) The maternal and child health services of health center will be obtained, iii) Epidemiologic data for pregnancy and birth can be obtained, iv) Manpower for birth and death reporting will be saved.
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