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검색결과 3,308건 처리시간 0.034초

Antihypertensive activity of Zingiber officinale and Korean ginseng in experimentally induced hypertension in rats

  • Mohan, M;Balaraman, R;Kasture, SB
    • Advances in Traditional Medicine
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    • 제7권3호
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    • pp.261-273
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    • 2007
  • We investigated the antihypertensive effect of Pet ether extract (PE) of ginger rhizome; its toluene fraction (TF) and Korean ginseng extract (KGE) in deoxycorticosterone acetate (DOCA) - salt induced and fructose induced hypertensive rats. In DOCA model, DOCA (25 mg/kg, once a week; s.c) was administered in uninephrectomised animals for 4 w. PE (50 mg/kg/day; p.o), TF (10 mg/kg/day; p.o) and KGE (30 mg/kg/day; p.o) were evaluated for their antihypertensive effect. In the fructose model, drinking water was replaced with fructose (10%) for five weeks to induce hypertension. PE (50 mg/kg/day; p.o) and KGE (30 mg/kg/day; p.o) were assessed for its antihypertensive effect in fructose model. After completion of the treatment schedule, vascular reactivity to various agonists like 5-HT, noradrenaline, adrenaline, phenylbiguanide and acetylcholine were recorded in rats of both the models. A cumulative dose response curve (CDRC) of 5-HT was carried out in isolated rat fundus strip of the fructose induced hypertensive rats. Chronic administration of PE (50 mg/kg/day; p.o), TF (10 mg/kg/day; p.o), and KGE (30 mg/kg/day; p.o) significantly reduced the blood pressure in DOCA salt whereas PE (50 mg/kg/day; p.o) and KGE (30 mg/kg/day; p.o) reduced the blood pressure in fructose induced hypertensive rats. Treatment with PE (50 mg/kg/day; p.o) and KGE (30 mg/kg/day; p.o) in fructose model for five weeks shifted the CDRC towards the right on rat fundus. The mechanism of action may partly involve the serotonergic antagonistic property.

급성 요통을 동반한 성인 측만증 환자에게 적용한 고유수용성신경근촉진법이 요부 능동 굴곡 관절가동 범위 및 일상생활동작에 미치는 영향 : 증례보고 (The Effects of PNF on Active Lumbar Flexion ROM and Activity of Daily Living for Adult Scoliosis with Low Back Pain)

  • 라은진;신승섭
    • PNF and Movement
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    • 제10권4호
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    • pp.33-40
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    • 2012
  • Purpose : The purpose of this study was to investigate the effects of PNF on active lumbar flexion ROM and difficulty of activity of daily living for adult scoliosis with low back pain. Methods : A 23-aged adult scoliosis with diagnosed herniated lumbar disc. The patient was treated by PNF for 30 minutes a day, 2 times a week during six weeks. Active lumbar flexion ROM and difficulty of activity of daily living were evaluated by the Modified-Modified Schober test and Oswestry Disability Questionnaire every week after treatment including the pretest of the first day of treatment. Results : There were a significant improvement in active lumbar flexion ROM between pretest and the last test. There were significant decreased in difficulty of activity of daily living positive between pretest and the last test. Conclusion : PNF will be useful for increasing active lumbar flexion ROM and decreasing the difficulty of activity of daily living positive for adult scoliosis with low back pain.

Effect of Weight Shift Training with Electrical Sensory Stimulation Feedback on Standing Balance in Stroke patients

  • Kim, Da-young;Cha, Yong-jun
    • 대한물리의학회지
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    • 제10권3호
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    • pp.39-45
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    • 2015
  • PURPOSE: The purpose of this study was to investigate the effect of weight shift training with electrical sensory simulation feedback on quiet standing balance in hemiplegic stroke patients. METHODS: 30 stroke patients were equally allocated at random to an experimental group or a control group. Patients in both two groups underwent comprehensive rehabilitation physical therapy for 30 minutes per day for 5 days per week for 4 weeks. Members of the experimental group received additional weight shift training with electrical sensory simulation feedback was conducted for 15 minutes after 30 minute sessions, whereas members of the control group underwent additional leftward/rightward weight shift training by themselves after 30 minutes per day for four weeks. COP (center of pressure) path lengths, COP velocities, and foot forces were measured before and immediately after the 4-week training period in both groups and results were compared. RESULTS: COP path lengths significantly decreased by 3% after training in the experimental group and this was significantly greater than that observed in the control group (p<0.05). In both groups, foot forces of affected sides showed significant increases after intervention, whereas foot forces of unaffected sides showed significant decreases (p<0.05). No significant difference was observed between the two groups with respect to these changes. CONCLUSION: Weight shift training using electrical sensory simulation feedback has a positive effect on quiet standing balance in hemiplegic stroke.

The Effects of Virtual Reality Based Treadmill Training on the Muscle Architecture of Gastrocnemius in Chronic Stroke Patients : Randomized Controlled Trial

  • Cho, KiHun
    • 대한물리치료과학회지
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    • 제24권3호
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    • pp.1-11
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    • 2017
  • Purpose: The purpose of this study was to investigate the effects of virtual reality based treadmill training on muscle architecture of gastrocnemius in chronic stroke patients. Methods: Thirty chronic stroke patients were randomly assigned to either the virtual reality based treadmill training (VRTT) group (n=15) or treadmill training (TT) group (n=15). Both groups participated in a standard rehabilitation program; in addition, the VRTT group participated in virtual reality based treadmill training for 30 minutes per day, three times per week, for 6 weeks, and TT group participated in treadmill walking training for 30 minutes per day, three times per week, for 6 weeks. Ultrasound image was used for measurement of pennation angle and muscle thickness of the medial gastrocnemius muscle at rest and during maximum voluntary contraction. Results: In the paretic side medial gastrocnemius muscle, greater improvement on the pennation angle and muscle thickness while resting and maximal voluntary contraction were observed in the VRTT group compared with the TT group. Conclusion: Findings of this study demonstrated that the virtual reality based treadmill training has an effect on muscle architecture of medial gastrocnemius in chronic stroke patients.

한국 청소년 여학생의 신체이미지 왜곡 실태와 영향요인 - 제14차 청소년건강행태조사 이용 - (Body Image Distortion and Related Factors among Female Adolescents in Korea - Based on the 14th Korean Youth Health Behavior Survey -)

  • 정낙영;계승희
    • 한국식생활문화학회지
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    • 제37권3호
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    • pp.256-264
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    • 2022
  • This study was undertaken to examine body image distortion among female adolescents and identify related factors. Raw data from the 14th Korean Youth Health Behavior Survey were used. The proportion of participants exhibiting body image distortion was 39.5%, with the ratio being higher among female students of normal weight as compared to underweight female students. Logistic regression revealed that the risk of having a distorted body image was higher among high school females than in middle school females having lower subjective academic performance and household economic status. In addition, the risk of having a distorted body image was higher for students who drank alcohol when compared to students who did not drink, for the group engaging vigorously in physical activity (exercise) more than three times per week as opposed to the group exercising less than three times per week, and for the group consuming less than one serving of fruit per day as compared to the group consuming more than one serving of fruit per day. Taken together, the results of this study indicate that continuous nutrition education needs to be provided so that adolescents can correctly perceive their body images and form desirable eating habits.

Effects of Kinesio Taping on Muscle Tone, Stiffness in Patients with Shoulder Pain

  • Choi, Jin-Ho
    • 대한물리의학회지
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    • 제12권3호
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    • pp.43-47
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    • 2017
  • PURPOSE: The purpose of this study was to identify the effects of physical therapy plus Kinesio taping (KT) on muscle tone and stiffness in patients with shoulder pain. METHODS: This study included 22 participants who were divided into the experimental group (n=11) who underwent a routine physical therapy with KT and the control group (n=11) who received the same physical therapy only. The physical therapy consisted of heat application and electrical stimulation. Heat was applied for 10 minutes and electrical stimulation was conducted for 20 minutes. Intervention was provided over a 1-week period, and frequency for muscle tone and stiffness was measured to determine changes in shoulder muscle status. The muscles were supraspinatus and deltoid. Measurements were taken before, after 1day, 3day and after 1 week to identify time-dependent effects of intervention. RESULTS: The effects of the intervention were significant in both groups, and effects were greater in the experimental group. Changes in muscle tone and stiffness were statistically significant in both groups and at varying time points (p<.05). CONCLUSION: Based on the improved muscle performance found in this study, KT is considered an effective intervention strategy for patients with shoulder pain when it is combined with conventional physical therapy.

SD Rats를 이용 1-hexene의 흡입독성 연구 (Study on Inhalation Toxicity of 1-Hexene in SD Rats)

  • 김현영;임철홍;정용현;이권섭;이성배;이준연;한정희;전윤석;이용묵
    • Environmental Analysis Health and Toxicology
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    • 제16권4호
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    • pp.211-221
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    • 2001
  • The purpose of this study was to investigate the acute (4 hours) and repeated-dose (6 hours a day, 5 days a week, 4 weeks) toxic effects of 1-hexene on Sprague-Dawley (SD) rats which were treated by inhalation. The results were as follows; 1. The median lethal concentration(LC$_{50}$) was estimated 52,694 ppm (confidence limit 95%; 49,494~55,447 ppm) in acute inhalation. Abnormal clinical signs related to the 1-Hexene were not observed with the acute inhalation dose. Cross findings of necropsy revealed on evidence of specific toxicity related to the 1-hexene. II. By repeated inhalation exposure the body weight of male were more or less reduced by the dose of 2,500 ppm and 5,000 ppm compared with control group. However there were no significant variation hematology and blood biochemistry for the exposed rats compared with the control rats. Abnormal clinical signs and gross findings of necropsy related to the 1-hexene were not shown. In conclusion when we exposed 1-hexene to SD rats for 4 weeks, 5 days per week, 6 hours per day, the Lowest observed effect level (LOEL) was over 2,500 ppm and Non observed effect level (NOEL) was below 500 ppm.

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허혈성 대퇴골두 괴사 유발견에서 전산화 단층 영상 평가 (Computed Tomographic Assessment of Experimentally Induced Legg-Calve-Prethes Disease in Dogs)

  • 배선희;성윤상;엄기동;김재훈;장광호
    • 한국임상수의학회지
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    • 제25권1호
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    • pp.9-14
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    • 2008
  • This purpose of this study was to describe and compare the radiographic and computed tomographic(CT) appearance of the experimentally induced Legg-Calve-Perthes Disease(LCPD) in dogs. LCPD was experimentally induced at the left femoral head in 7 litters of a dog. The lesions were evaluated with radiography, CT, and contrast CT every week from day 7 to day 70 after operation. Histopathologic examination was performed on 92th day after operation. Every images were evaluated according to the staging system of the osteonecrosis published by Association Research of Circulation Osseous in 1997 and the scoring(0-4). On CT scan, diffuse porotic lesion and focal sclerotic lesion were detected on day 14 and on day 21 after operation, respectively. Subchondral fracture, articular collapse and crescent sign with decreased attenuation were shown on day 28 after operation for the first time and no change of the sign were detected from operation day 9 to day 70 after operation. Focal porotic lesion and irregular radiopacity of femoral head were detected on day $41{\pm}7.48$ and on day $51{\pm}5.29$ after operation respectively on radiographs. In scoring evaluation, 2.00 was scored on day 14 after operation on CT scan, on day 56 after operation on radiographs, respectively This study has shown that CT is more suitable for early diagnosis of LCPB and has superior sensitivity than radiography. Also, CT has been expected to be important for staging and treatment of LCPD.

응급실 방문 환아에 대한 임상적 고찰 (A Clinical Study of the Pediatric Patients Visiting Emergency Center)

  • 김신정;문선영
    • Child Health Nursing Research
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    • 제5권1호
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    • pp.97-106
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    • 1999
  • The purpose of this study was to provide basic data of nursing intervention through understanding disease pattern of pediatric patients. Data were collected from 3,016 patients who visited emergency center of I university Hospital during one year period from January to December, 1997. The results were as follows : 1. The most common type of disease was respiratory disease (26.7%). 2. According to the developmental age, toddler (35%) ranked first followed by preschooler(22.1%), infant(18.5%), schooler(16.0%), adolescent (5.6%), neonate (2.7%). 3. The proportion of males to females, male patients(59.8%) outnumbered female(40.2%) by the ratio of 1.48 ; 1. 4. Visiting patients were seasonally more frequent in spring(29.8%) and summer (29.3%) than fall or winter. 5. Comparing weekly distribution, week end involing holiday outnumbered week day(48.5%). 6. The visiting time predominattly high from 8 : 00 PM to 0 : 00 AM(29.8%) during a day. 7, The majority duration of stay at Emergency center was 1-6 hours. 8. Most patients dischrged from the emergency center in good condition(76.5%).

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울산시 주민의 건강을 위한 식행동 조사 연구 (Consumption Pattern of Meals among Ulsan City Residents)

  • 신애숙;김광기
    • 동아시아식생활학회지
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    • 제9권2호
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    • pp.135-148
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    • 1999
  • This is a descriptive study of consumption Patterns of how to take meals in everyday life. The data used was collected from a probability sample by multi-stage cluster sampling, drawn from those who were living in the Ulsan Metropolitan Area. Face-to-face interviews were conducted by trained interviewers with a household member who was between the ages of 15 and 60 in 1989 and had the earliest birthday, resulting in a sample of 1,232 respondents. Univariate and bivariate analyses were made to describe behavioral patterns of taking meals. Meal-taking behaviors under this study include frequency of taking meals per day, regularity of taking meals, which meal to skip, number of frequency of taking a meal by oneself. reasons of skipping and irregular meals, and eatting out. Half of the respondents reported to take meals three times a day, while those who skipped at least a meal reported as one most frequently skipped. Of reasons not to take a meal on a regular basis, "too busy to eat" was most frequently mentioned. Only 32.8% of the respondents reported dining-out once a week.ce a week.

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