• Journal of Nutrition and Health
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• v.41 no.3
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• pp.242-253
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• 2008

It is a common clinical practice to recommend taking iron supplements for pregnant women during gestation. Although it is required to ensure adequate iron stores during pregnancy, there has been some debate over the interference effects of excessive iron load, because it is possible to compete in the transport in the intestine and placenta and in binding to serum proteins of other trace minerals. In this study, maternal and neonatal serum concentrations of Fe, Zn, Cu, Se, Cr, Mn, and Co were assessed along with maternal Fe intakes. A total of 124 pregnant women and their term neonates participated voluntarily in this research. The women were divided into one of the three groups {high Fe intake (HFI), median Fe intake (MFI), and low Fe intake (LFI)} by their total Fe intakes and one of the two groups (Anemic and Normal) by their Fe nutritional status. All the data were compared among the three groups and between the two groups also. Total Fe intakes of HFI, MFI, and LFI groups were 140.8 ${\pm}$ 76.1, 68.0 ${\pm}$ 11.2, and 30.2 ${\pm}$ 8.6 mg/day, respectively. Those of Anemic and Normal groups were 90.1 ${\pm}$ 74.8 and 86.6 ${\pm}$ 46.8 mg/day, respectively. Maternal Hb concentration and Hct were not significantly different among HFI, MFI, and LFI groups but those were significantly different between Anemic and Normal groups. However, neonatal Hb concentration was not significantly different among HFI, MFI, and LFI groups and between Anemic and Normal groups either. Maternal serum Fe concentrations of the three groups, HFI, MFI, and LFI, were similar but that of Anemic group was significantly lower compared to Normal group. However, there was no significant difference in neonatal serum Fe concentrations among the three groups and between the two groups either. Serum concentrations of the other trace minerals in both mothers and neonates were not significantly different among HFI, MFI, and LFI groups and between Anemic and Normal groups. In addition, in the maternal serum, Fe concentration was positively correlated to Zn and Se concentration, respectively. As for the neonatal serum, Fe concentration showed a positive correlation to Zn, Cu, Mn, Se, and Co concentration, respectively. No trace mineral concentration was found to correlate negatively to Fe concentration in both maternal and neonatal serum, The results in this study indicate that Fe intakes of pregnant women, even if it is considerably above the level of estimated average requirement (EAR), may not affect serum Fe concentration in both mothers and neonates. In addition it might not influence adversely on the availability of other trace minerals including Zn and Cu in both mothers and neonates.

• Journal of Korean Society of Transportation
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• v.27 no.4
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• pp.155-166
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• 2009

Road design safety assessment by existing tools and methods have normally been examined by expert judgements using design documents and on-site inspections. The existing methods, however, have two main problems such as insufficiency of objectiveness and inability to measure effects of accident countermeasures. This paper studies ways to develop a road safety assessment system through reviewing the IHSDM developed in USA. The crash prediction module of IHSDM calculate accident frequency and rate of roadway segments using accident prediction models and accident modification factors for safety evaluation. The methodology of evaluation and development of accident modification factors somewhat overcome the problems of the existing methods. In spite of these advantages, IHSDM could not relevantly reflect characteristics of domestic rural roadways since it overestimate the number of accidents and rate of korean rural roadways. Especially, IHSDM may not evaluate or consider land use patterns of Korean roadways, and futhermore, original environment on base conditions used to develop IHSDM may not be different from ours. The user requirements being developed for a road safety assessment system for Korean roadways include enhanced flexibility and diversity of data input-output processes.

• Korean Journal of Ecology and Environment
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• v.50 no.4
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• pp.411-421
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• 2017

Understanding the need for temperature regulation, behavior, and ecology of hibernating bats provides the possibility of conservation and management for target species. Our objective in this study was to improve understanding of the population trend and ecological requirement in Myotis formosus population in South Korea. From 2007 to 2016, total of 58 hibernacula for Myotis formosus were found across the country. Of the 58 hibernating sites of Myotis formosus, 86% (n=49) were abandoned mines and 14% (n=8) were natural caves. During the survey period, 28 (5%) bats of total 570 bats were observed in natural caves (n=8) and 542 (95%) bats were observed in abandoned mines (n=49). The internal environments of hibernacula of M. formosus were highly stable despite dramatic variation in the external environment. Specifically, we examined the population trend of the endangered bat Myotis formosus in South Korea by long-term monitoring for hibernation sites. The population trend of endangered species M. formosus showed a marked stable in hibernating population. Our results indicate that a tightly collected long-term data set may help to establish the initial approximation of population trends and manage to threats for the endangered bat species.

• Korean Journal of Agricultural and Forest Meteorology
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• v.20 no.2
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• pp.228-232
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• 2018

Process-based crop models have been used to assess the impact of climate change on crop production. These models are implemented in procedural or object oriented computer programming languages including FORTRAN, C++, Delphi, Java, which have a stiff learning curve. The requirement for a high level of computer programming is one of barriers for efforts to develop and improve crop models based on biophysical process. In this study, we attempted to develop a Chinese cabbage model using Microsoft Excel with Visual Basic for Application (VBA), which would be easy enough for most agricultural scientists to develop a simple model for crop growth simulation. Results from Soil-Plant-Atmosphere-Research (SPAR) experiments under six temperature conditions were used to determine parameters of the Chinese cabbage model. During a plant growing season in SPAR chambers, numbers of leaves, leaf areas, growth rate of plants were measured six times. Leaf photosynthesis was also measured using LI-6400 Potable Photosynthesis System. Farquhar, von Caemmerer, and Berry (FvCB) model was used to simulate a leaf-level photosynthesis process. A sun/shade model was used to scale up to canopy-level photosynthesis. An Excel add-in, which is a small VBA program to assist crop modeling, was used to implement a Chinese cabbage model under the environment of Excel organizing all of equations into a single set of crop model. The model was able to simulate hourly changes in photosynthesis, growth rate, and other physiological variables using meteorological input data. Estimates and measurements of dry weight obtained from six SPAR chambers were linearly related ($R^2=0.985$). This result indicated that the Excel/VBA can be widely used for many crop scientists to develop crop models.

• Land and Housing Review
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• v.3 no.4
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• pp.343-355
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• 2012

The purpose of this paper is to propose reasonable improvements of demand estimation methods of commercial site through the case study. Thus, we investigated the problems and limitation of demand estimation methods and process applied to primary and secondary new towns in Korea. And we suggested the way to reduce error of demand estimation and to raise its objectivity. The result of case analysis is as follows; firstly, it was insufficient to consider location, hierarchy and change of land use like mixed-use development in commercial site. Secondly, improper comparable group or operated relevant index data in the same light were selected the aggregated unit requirement method such as comparative analogy method and planning guidelines. Thirdly, there were many cases that demand estimation value was amended arbitrarily, and it tends to occur a serious reliability problem. Therefore, to improve these problems and to make better use of demand estimation hereafter are required the sublation of arbitrary commercial sphere's settings, the making of comparative group considered development conditions, and putting forward objective revision basis.

• Journal of Cadastre & Land InformatiX
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• v.49 no.2
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• pp.123-134
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• 2019

The introduction of the world geodetic reference system in cadastral sector can apply the international standardization of cadastral survey and can be the basis for the creation of new industries by merging with other industries based on spatial information. With the introduction of the world geodetic reference system, non-coincidence land may cause problems which are whether the cadastral record and the real estate register are not consistent, etc. This problem infringes on the protection of ownership of citizens suggested in the main purpose of ｢Act On The Establishment, Management, Etc. Of Spatial Data｣. We have analyzed at overlapping cases between private land and overlapping cases between national and public land and suggested institutional improvement measures to solve problems arising on the site. As a result, it will be necessary to introduce a transformation verification measure by the world geodetic reference system in order to assign a function as a cadastral records to mapping converted to the world geodetic reference system. It is also expected that the legal and institutional basis should be established for alert adjustment and positioning through verification measures. Finally, it is difficult to determine the transformation factor as the co-ordinates of common points also differ because survey results vary by work area. Therefore, it is deemed necessary to consider the requirement to use the cadastral measurement basis by the world geodetic reference system in 2021.

• Proceedings of the Microbiological Society of Korea Conference
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• 2008.05a
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• pp.23-25
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• 2008

Serum complement proteins comprise an important system that is responsible for several innate and adaptive immune defence mechanisms. There were three well described pathways known to lead to the generation of a C3 convertase, which catalyses the proteolysis of complement component C3, and leads to the formation of C3 opsonins (C3b, iC3b and C3d) that fix to bacteria. A pivotal step in the complement pathway is the assembly of a C3 convertase, which digests the C3 complement component to form microbial-binding C3 fragments recognized by leukocytes. The spleen clears microorganisms from the blood. Individuals lacking this organ are more susceptible to Streptococcus pneumoniae. Innate resistance to S. pneumoniae has previously been shown to involve complement components C3 and C4, however this resistance has only a partial requirement for mediators of these three pathways, such as immunoglobulin, factor B and mannose-binding lectin. Therefore it was likely that spleen and complement system provide resistance against blood-borne S. pneumoniae infection through unknown mechanism. To better understand the mechanisms involved, we studied Specific intracellular adhesion molecule-grabbing nonintegrin (SIGN)-R1. SIGN-R1, is a C-type lectin that is expressed at high levels by spleen marginal-zone macrophages and lymph-node macrophages. SIGN-R1 has previously been shown to be the main receptor for bacterial dextrans, as well as for the capsular pneumococcal polysaccharide (CPS) of S. pneumoniae. We examined the specific role of this receptor in the activation of complement. Using a monoclonal antibody that selectively downregulates SIGN-R1 expression in vivo, we show that in response to S. pneumoniae or CPS, SIGN-R1 mediates the immediate proteolysis of C3 and fixation of C3 opsonins to S. pneumoniae or to marginal-zone macrophages that had taken up CPS. These data indicate that SIGN-R1 is largely responsible for the rapid C3 convertase formation induced by S. pneumoniae in the spleen of mice. Also, we found that SIGN-R1 directly binds C1q and that C3 fixation by SIGN-R1 requires C1q and C4 but not factor B or immunoglobulin. Traditionally C3 convertase can be formed by the classical C1q- and immunoglobulin-dependent pathway, the alternative factor-B-dependent pathway and the soluble mannose-binding lectin pathway. Furthermore Conditional SIGN-R1 knockout mice developed deficits in C3 catabolism when given S. pneumoniae or its capsular polysaccharide intravenously. There were marked reductions in proteolysis of serum C3, deposition of C3 on organisms within SIGN-$R1^+$ spleen macrophages, and formation of C3 ligands. The transmembrane lectin SIGN-R1 therefore contributes to innate resistance by an unusual C3 activation pathway. We propose that in the SIGN-R1 mediated complement activation pathway, after binding to polysaccharide, SIGN-R1 captures C1q. SIGN-R1 can then, in association with several other complement proteins including C4, lead to the formation of a C3 convertase and fixation of C3. Therefore, this new pathway for C3 fixation by SIGN-R1, which is unusual as it is a classical C1q-dependent pathway that does not require immuno globulin, contributes to innate immune resistance to certain encapsulated microorganisms.

• Journal of Animal Science and Technology
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• v.62 no.2
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• pp.180-186
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• 2020

The objective of this study was to determine the effect of replacing corn with soy hulls on nutrient digestibility of growing pigs. Three experimental diets were tested using a 3 × 3 Latin square design using three barrows per group (Landrace × Yorkshire × Duroc, average initial body weight of 36.9 ± 4.0 kg) in individual metabolic cages. The dietary treatments were the control (CON) basal diet (corn-soybean meal based diet), whereas in the test diets, soy hulls were included at 5% (H1), 10% (H2), gradually replacing corn. The daily feed allowance was adjusted to 2.7 times the maintenance requirement for digestible energy (DE) (2.7 × 110 kcal of DE/kg BW^0.75). Intake of crude fiber (CF) was different among treatments (p < 0.05). Pigs fed with H2 diet excreted higher concentrations of dry matter (DM), and CF than pigs fed with H1 diet and basal diet (p < 0.05). Pigs fed with H1 and H2 diets excreted higher concentrations of crude protein (CP) than pigs fed with CON diet (p < 0.05). The apparent total tract digestibility (ATTD) of CF from H1 and H2 diets were higher than CON diet (p < 0.05). Pigs fed with H2 diets were significantly lower (p < 0.05) the ATTD of CP than the pigs fed with CON and H1 diets. The current data suggest that 10% inclusion soy hulls can slightly decrease CP digestibility. However, soy hulls considerably increased CF digestibility.It is concluded that 5% soy hulls may be a usable alternative to corn in growing pig diets.

• Environmental and Resource Economics Review
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• v.23 no.2
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• pp.187-224
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• 2014

We present key issues to consider in estimating damages from price-fixing cases and then apply the procedure addressing those issues to a transportation fuel market. Among the five methods of overcharge calculation, the regression analysis incorporating the yardstick method is the best. If the price equation relates the domestic price to the foreign price and the exchange rate as in the transportation fuel market, the functional form satisfying both logical consistency and modeling flexibility is the log-log functional form. If the data under analysis is of time series in nature, then the ARDL model should be the base model for each market and the regression analysis incorporating the yardstick method combines these ARDL equations to account for inter-market correlation and arrange constant terms and collusion-period dummies across component equations appropriately so as to identify the overcharge parameter. We propose a two-step test for the benchmarked market: (a) conduct market-by-market Spearman or Kendall test for randomness of the individual market price series first and (b) then conduct across-market Friedman test for homogeneity of the market price series. Statistical significance is the minimal requirement to establish the alleged proposition in the world of uncertainty. Between the sensitivity analysis and the model selection process for the best fitting model, the latter is far more important in the economic analysis of damage in price-fixing litigation. We applied our framework to a transportation fuel market and could not reject the null hypothesis of no overcharge.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.4 no.4
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• pp.393-400
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• 2006

In design of a deep geological repository for the high level wastes, it is very important that the temperature of the bentonite block should not be over $100^{\circ}C$ to maintain the integrity of the bentonite buffer block from the decay heat. In this study, for the layout of the repository to meet the requirement, the analysis of the disposal tunnel and disposal pit spacing was carried out. To do this, based on the reference repository concept, several cases of cooling times and disposal tunnel and disposal pit spacing were compared. The thermal stabilities of the disposal systems were analyzed in terms of the cooling time and spacing. The results showed that it was more desirable to determine the layout of the repository in terms of disposal pit spacing than the disposal tunnel spacing. The results of these analyses can be used in the deep geological repository design. The detailed analyses with the exact site characteristics data will reduce the uncertainty of the results.