• Title/Summary/Keyword: Data Migration

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Early Growth Response Protein-1 Involves in Transforming Growth factor-β1 Induced Epithelial-Mesenchymal Transition and Inhibits Migration of Non-Small-Cell Lung Cancer Cells

  • Shan, Li-Na;Song, Yong-Gui;Su, Dan;Liu, Ya-Li;Shi, Xian-Bao;Lu, Si-Jing
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.4137-4142
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    • 2015
  • The zinc finger transcription factor EGR 1 has a role in controlling synaptic plasticity, wound repair, female reproductive capacity, inflammation, growth control, apoptosis and tumor progression. Recent studies mainly focused on its role in growth control and apoptosis, however, little is known about its role in epithelial-mesenchymal transition (EMT). Here, we aim to explore whether EGR 1 is involved in TGF-${\beta}1$-induced EMT in non-smallcell lung cancer cells. Transforming growth factor (TGF)-${\beta}1$ was utilized to induce EMT in this study. Western blotting, RT-PCR, and transwell chambers were used to identify phenotype changes. Western blotting was also used to observe changes of the expression of EGR 1. The lentivirus-mediated EGR 1 vector was used to increase EGR 1 expression. We investigated the change of migration to evaluate the effect of EGR 1 on non-small-cell lung cancer cells migration by transwell chambers. After stimulating with TGF-${\beta}1$, almost all A549 cells and Luca 1 cells (Non-small-cell lung cancer primary cells) changed to mesenchymal phenotype and acquired more migration capabilities. These cells also had lower EGR 1 protein expression. Overexpression of EGR 1 gene with EGR 1 vector could decrease tumor cell migration capabilities significantly after adding TGF-${\beta}1$. These data s howed an important role of EGR 1 in the EMT of non-small-cell lung cancer cells, as well as migration.

Platform Design for Optimal Migration Cost of Mobile Agents (이동 에이전트의 최적 이주 비용을 위한 플랫폼 설계)

  • 김완성;복경수;신재룡;유재수
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.8 no.1
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    • pp.137-149
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    • 2004
  • A new software paradigm is required on the development of network and various service requirements. With this, many studies on a mobile agent have been made. For the execution of the mobile agent, migration is the most important factor that influences the performance of the mobile agent. In this paper we propose the method that leads to high migration efficiency in order to improve the performance. The features of our migration technique are as follows. First, the migration technique creates the dynamic itinerary that appropriately copes with the network conditions and the platform changes to improve the agent execution efficiency. Second, it perfecters an executed code to reduce the amount of the mobile data and reduces the execution time by instantiating the agent in advance. Third, it improves the execution efficiency by using the checkpoint-based recovery method that does not execute the agent again and recovers the process states even though the errors take place. Though the simulation we compare the proposed method with the existing methods. The simulation result shows that the proposed method outperform the existing methods in terms of migration.

An Analysis of Urban Migration and Local Government Finance (도시의 인구이동과 지방재정에 관한 연구)

  • 김헌민
    • Korea journal of population studies
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    • v.14 no.2
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    • pp.1-17
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    • 1991
  • While various fiscal measures have been used to influence regional capital inflow or industrial location, the effect of fiscal variables on labor mobility has been little understood. Understanding the relationship between the composition of local public and urban migration would enhance the city govenment's ability to pursue an appropriate population policy. In order to examine the potential for local public finance to be utilized as a policy tool in directing urban population growth, this paper analyzes the impact of local government financial structure on urban migration. In examining the data on local government finance and the changes in population of Korean cities during the last ten years, it was found that cities with high per capita expenditure in regional development have experienced high population growth rates. In this study migration equations were constructed using various fiscal variables such as the proportion of special account expenditures which are mostly spent for local development purposes, per capita regional development expenditure, degree of local financial independence and per capita net fiscal benefit, along with other explanatory variables. The results of regression analysis showed that city government's regional development expenditure variables have a positive effect on urban net migration and a negative effect on outmigration. Fiscal independence and per capita net fiscal benefit had mixed effects on in and out migration variables, implying that local tax burden does not consistently deter inmigration or induce outmigration. Based on the results of this study some important policy implications can be found regarding local government's fiscal policies. Those cities seeking to attract higher population inflow should make a greater effort in appropriating local expenditures for regional development purposes such as infrastructure, housing, and transportation. city governments should not be too concerned about high local tax burden or necessarily seek to enhance financial independence for these factors do not exert a clear influence on urban population growth or labor supply.

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A Dynamic Routing Protocol for Energy Effectiveness in Wireless Sensor Networks (무선 센서 네트워크에서의 에너지 효율 개선을 위한 동적 라우팅 프로토콜)

  • Oh, Sei-Woong;Jun, Sung-Taeg
    • Journal of Information Technology Services
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    • v.6 no.1
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    • pp.141-149
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    • 2007
  • Sensor node's mobility brings new challenges to data dissemination in large sensor networks. Frequent location updates of sensor nodes can lead to both excessive drain of sensor's limited battery supply and increased collisions in wireless transmissions. Conventional studies for routing protocols in wireless sensor networks are not enough to cover energy consumption and migration of sensor nodes. This study proposes a dynamic routing protocol based on the SPIN considering energy consumption and the migration, and also shows the effectiveness of the proposed routing protocol.

EFFICIENT MANAGEMENT OF VERY LARGE MOVING OBJECTS DATABASE

  • Lee, Seong-Ho;Lee, Jae-Ho;An, Kyoung-Hwan;Park, Jong-Hyun
    • Proceedings of the KSRS Conference
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    • v.2
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    • pp.725-727
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    • 2006
  • The development of GIS and Location-Based Services requires a high-level database that will be able to allow real-time access to moving objects for spatial and temporal operations. MODB.MM is able to meet these requirements quite adequately, providing operations with the abilities of acquiring, storing, and querying large-scale moving objects. It enables a dynamic and diverse query mechanism, including searches by region, trajectory, and temporal location of a large number of moving objects that may change their locations with time variation. Furthermore, MODB.MM is designed to allow for performance upon main memory and the system supports the migration on out-of-date data from main memory to disk. We define the particular query for truncation of moving objects data and design two migration methods so as to operate the main memory moving objects database system and file-based location storage system with.

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Migration and Distribution of the Common Squid (Todarodes pacificus) in Korean Waters (한국주변해역 살오징어(Todarodes pacificus)의 회유 및 분포특성)

  • Kim, Yoon-Ha;Choi, Kwangho;Lee, Chung Il
    • Journal of Environmental Science International
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    • v.26 no.2
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    • pp.173-181
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    • 2017
  • Catch data for the common squid (Todarodes pacificus), classified by squid-jigging fisheries per grid (size: $0.5^{\circ}latitude{\times}0.5^{\circ}longitude$), and the water temperature values KODC (Korea Ocean Data Center) were collected for the 1980-2009 period to study the changes in squid distribution and migration with climate regimes (1980s, 1990s, and 2000s). The primary fishing period in the 1990s and 2000s was approximately 2-3 months earlier than that in the 1980s. Especially in the East Sea, the fishing grounds in the 1980s stayed longer at high latitudes than those in the other decades. Moreover, in the 1980s, centers of the fishing ground were located near the Yamato bank (central East Sea), whereas in the 1990s and 2000s, they were situated near the southeastern coast of the Korean peninsula.

Variability of Vertical Distribution of Volume Scattering Observed in the Shallow Water (천해 체적 산란강도의 수직분포 변동성)

  • 박경주;김은혜;강돈혁;나정열
    • The Journal of the Acoustical Society of Korea
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    • v.22 no.1
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    • pp.69-77
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    • 2003
  • Measurements of backscattered intensity were made over a shallow water using 300 ㎑and 1200 ㎑ bottom mounted ADCP (Acoustic Doppler Current Profiler) to determine the temporal variability of vertical distribution of high-frequency volume scattering strength (Sv). The variability of Sv in relatively deep water column(85 m and 113 m was due to the daily vertical migration, probably of larger zooplankton. However it was not found with 1200㎑ data at shallow water column. From the empirical orthogonal function (EOF) analysis using 1200㎑ data, the vertical distribution of the first mode eigenvectors of Sv is characterized by the presence of the maximum values near the bottom of the water.

Analyzing Migration Decision-Making Characteristics Based on Population Change Pattern and Distribution of Basic Living Services in Rural Areas (농촌지역 인구변화 특성 및 기초생활서비스 분포 특성을 고려한 이주 의사 결정 요인 분석)

  • Kim, Suyeon;Choi, Jin-Ah
    • Journal of Korean Society of Rural Planning
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    • v.28 no.4
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    • pp.1-9
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    • 2022
  • Rural decline due to the decrease of the local population is an inevitable phenomenon, and a vicious cycle has been formed between a lack of basic living services and a population decrease in rural areas. Therefore, the study aims to derive the migration decision-making characteristics based on basic living service infrastructure data in rural areas. To do this, the population change over the past 20 years was categorized into six types, and the relationship between the classified population change types and the number of basic living service infrastructures was analyzed using decision tree analysis. Of the total 3,501 regions, 801 regions were the continuous decline type, of which 740 were rural areas. On the other hand, among 569 regions that were the continuous increase type, 401 regions were urban areas, confirming the population imbalance between rural and urban areas. As a result of the decision tree analysis on the relationship between population change types and the distribution of basic living service infrastructure, the number of daycare centers was derived as an important variable to classify the continuous increase type. Hospitals, parks, and public transportation were also found to be major basic living services affecting the classification of population change types.

Performance Evaluation of WAN Storage Migration Scheme for Cloud Computing Environment (클라우드 컴퓨팅 환경을 위한 WAN 스토리지 이주 기법 성능평가)

  • Chang, Jun-Hyub;Lee, Won-Joo;Jeon, Chang-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.5
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    • pp.1-7
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    • 2012
  • In this paper, we design and implement the simulator for WAN storage replication model performance evaluation in cloud computing environment. Each cloud of simulator is composed of virtual machine emulator and storage emulator. The virtual machine emulator is composed of read/write ratio module, the read/write sequence combination module, and the read/write request module. The storage emulator is composed of storage management module, data transfer module, read/write operations module, and overhead processing module. Using the simulator, we evaluate performance of migration scheme, pre-copy and the post-copy, considering about read/write ratio, network delay, and network bandwidth. Through simulation, we have confirmed that the average migration time of pre-copy was decreased proportional to the read operation. However, average migration time of post-copy was on the increase. Also, the average migration time of post-copy was increased proportional to the network delay. However, average migration time of pre-copy was shown uniformly. Therefore, we show that pre-copy model more effective to reduce the average migration time than the post-copy model. The average migration time of pre-copy and post-copy were not affected by the change of network bandwidth. Therefore, these results show that selects the storage replication model to be, the network bandwidth know not being the important element.

The Effects of Status Inconsistency between Spouses on Migration in the United States: Propensities and Rural-Urban Destination Selections (미국에서 이동시 부분간 지위불일치의 효과 : 경향과 농촌-도시 목적지 선택을 중심으로)

  • Lee Ji-Youn;Toney Michael B.;Berry Helen E.
    • Korea journal of population studies
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    • v.26 no.2
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    • pp.197-219
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    • 2003
  • Using the panel data from the National Longitudinal Survey of Youth 79, we test the effects of relative status inconsistency within American young couples on the direction of migration as well as on migration propensities. Key findings in this study indicate that only couples in which the wife's education is greater than the husband's education are less likely to migrate than couples for which the wife's status is as lower than the husband's. There are no differences in the propensity for rural couples to migrate to urban counties or for urban couples to migrate to rural counties based on status inconsistency between spouses. However, we find that there is the gendered difference in the effect of status inconsistency on the probability of family migration. A spouse's higher status has an impact on a wife's probability of migration but does not affect a husband's migration propensity in a comparable situation. These findings are most consistent with a gender role perspective on migration since increases in the wife's status have little effect on family migration, once the presence and age of children is controlled.