• BMB Reports
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• 제34권6호
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• pp.489-495
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• 2001

DNA damage by UV and environmental agents are the major cause of genomic instability that needs to be repaired, otherwise it give rise to cancer. Accordingly, mammalian cells operate several DNA repair pathways that are not only responsible for identifying various types of DNA damage but also involved in removing DNA damage. In mammals, nucleotide excision repair (NER) machinery is responsible for most, if not all, of the bulky adducts caused by UV and chemical agents. Although most of the proteins involved in NER pathway have been identified, only recently have we begun to gain some insight into the mechanism by which proteins recognize damaged DNA. Binding of Xeroderma pigmentosum group C protein (XPC)-hHR23B complex to damaged DNA is the initial damage recognition step in NER, which leads to the recruitment of XPA and RPA to form a damage recognition complex. Formation of damage recognition complex not only stabilizes low affinity binding of XPA to the damaged DNA, but also induces structural distortion, both of which are likely necessary for the recruitment of TFIIH and two structure-specific endonucleases for dual incision.

• 한국해양공학회지
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• 제14권1호
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• pp.80-87
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• 2000

Despite many combined research efforts outstanding needs exist to develop robust safety-estimation methods for large complex structures. This paper presents a practical damage identification scheme which can be applied to truss structures using only limited modal responses. firstly a theory of pattern recognition (PR) is described. Secondly existing damage-detection algorithms are outlined and a newly-derived algorithms for truss structures. Finally the feasibility of the proposed scheme is evaluated using numerical examples of plane truss structures.

• 대한토목학회논문집
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• 제38권4호
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• pp.621-625
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• 2018

본 연구는 딥러닝을 활용하여 교량 점검보고서에서 손상 및 손상 인자를 자동으로 식별하는 방법을 제안한다. 교량 점검보고서에는 점검 결과 발견된 손상 및 원인 분석 결과가 기록되어 있다. 그러나 점검보고서의 양이 방대하여 인력으로 보고서로부터 정보를 수집하는 데 한계가 있다. 따라서 본 연구에서는 딥러닝 기반 개체명 인식 방법을 활용하여 교량 점검보고서 텍스트로부터 손상 및 손상 인자에 해당하는 단어들을 식별할 수 있는 모델을 제안한다. 모델 구현의 주요 방법론으로는 개체명 인식(Named Entity Recognition), 워드 임베딩(Word Embedding), 딥러닝의 일종인 순환신경망(Recurrent Neural Network)을 활용하였다. 실험 결과 제안된 모델은 1)훈련 데이터에 포함된 손상 및 손상 인자 단어들을 잘 식별할 수 있고, 2)단어 주변 맥락에 따라 특정 단어가 손상에 해당하는지 손상 인자에 해당하는지 잘 판별할 수 있을 뿐만 아니라, 3)훈련 데이터에 포함되지 않은 새로운 종류의 손상 단어도 잘 인식할 수 있는 것으로 확인되었다.

• Structural Monitoring and Maintenance
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• 제6권3호
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• pp.173-190
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• 2019

Steel-confined reinforced concrete (SCRC) columns feature highly complex and invisible mechanisms that make damage evaluation and pattern recognition difficult. In the present article, the prevailing acoustic emission (AE) technique was applied to monitor and evaluate the damage process of steel-confined RC columns in a quasi-static test. AE energy-based indicators, such as index of damage and relax ratio, were proposed to trace the damage progress and quantitatively evaluate the damage state. The fuzzy C-means algorithm successfully discriminated the AE data of different patterns, validity analysis guaranteed cluster accuracy, and principal component analysis simplified the datasets. A detailed statistical investigation on typical AE features was conducted to relate the clustered AE signals to micro mechanisms and the observed damage patterns, and differences between steel-confined and unconfined RC columns were compared and illustrated.

• International Journal of Railway
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• 제7권4호
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• pp.94-99
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• 2014

Urban railway systems are located under populated areas and are mostly constructed for underground structures which demand high standards of structural safety. However, the damage progression of underground structures is hard to evaluate and damaged underground structures may not effectively stand against successive earthquakes. This study attempts to examine initial damage-stage and to access structural damage condition of the ground structures using Earthquake Damage Monitoring (EDM) system. For actual underground structure, vulnerable damaged member of Ulchiro-3ga station is chosen by finite element analysis using applied artificial earthquake load, and then damage pattern and history of damaged members is obtained from measured acceleration data introduced unsupervised learning recognition. The result showed damage index obtained by damage scenario establishment using acceleration response of selected vulnerable members is useful. Initial damage state is detected for selected vulnerable member according to established damage scenario. Stiffness degrading ratio is increasing whereas the value of reliability interval is decreasing.

• 대한토목학회논문집
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• 제42권1호
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• pp.117-126
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• 2022

현재 국내 교량 구조물은 지속적으로 증가 및 대형화되고 있으며 그에 따라 공용된 지 30년 이상 된 노후 교량도 꾸준히 늘어나고 있다. 교량 노후화 문제는 국내뿐 아니라 전 세계적으로도 심각한 사회 문제로 다루어지고 있으며, 기존 인력 위주의 점검 방식은 그 한계점을 드러내고 있다. 최근 들어 딥러닝 기반의 영상처리 알고리즘을 활용한 각종 교량 손상탐지 연구가 이루어지고 있지만 교량 손상 데이터 세트의 한계로 인하여 주로 균열 1종에 국한된 교량 손상탐지 연구가 대부분이고, 이 또한 Close set 분류모델 기반 탐지방식으로서 실제 교량 촬영 영상에 적용했을 시 배경이나 기타 객체 등 학습되지 않은 클래스의 입력 이미지들로 인하여 심각한 오인식 문제가 발생할 수 있다. 본 연구에서는 균열 포함 5종의 교량 손상을 정의 및 데이터 세트를 구축해서 딥러닝 모델로 학습시키고, OpenMax 알고리즘을 적용한 Open set 인식 기반 교량 다중손상 인식 모델을 개발했다. 그리고 학습되지 않은 이미지들을 포함하고 있는 Open set에 대한 분류 및 인식 성능평가를 수행한 후 그 결과를 분석했다.

• Structural Monitoring and Maintenance
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• 제5권2호
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• pp.231-242
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• 2018

Subway tunnel structure has been rapidly developed in many cities for its strong transport capacity. The model-based damage detection of subway tunnel structure is usually difficult due to the complex modeling of soil-structure interaction, the indetermination of boundary and so on. This paper proposes a new data-based method for the damage detection of subway tunnel structure. The root mean square acceleration and cross correlation function are used to derive a statistical pattern recognition algorithm for damage detection. A damage sensitive feature is proposed based on the root mean square deviations of the cross correlation functions. X-bar control charts are utilized to monitor the variation of the damage sensitive features before and after damage. The proposed algorithm is validated by the experiment of a full-scale two-rings subway tunnel lining, and damages are simulated by loosening the connection bolts of the rings. The results verify that root mean square deviation is sensitive to bolt loosening in the tunnel lining and X-bar control charts are feasible to be used in damage detection. The proposed data-based damage detection method is applicable to the online structural health monitoring system of subway tunnel lining.

• 한국구조물진단유지관리공학회 논문집
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• 제24권6호
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• pp.77-84
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• 2020

본 논문에서는 사장교와 같은 장대형 구조물의 손상위치를 판단할 수 있는 손상평가 기법을 개발하고, 개발한 기법의 성능을 실험을 통하여 검증하고자 하였다. 손상평가 기법은 무손상 데이터가 확보되지 않은 상태에서 구조물의 손상평가가 가능하고, 구조물의 응답 데이터의 분석만으로 손상위치를 판단할 수 있는 데이터를 추출하는 것을 목표로 하였다. 이러한 목표를 완성하기 위하여, 손상 위치 판별을 위하여 통계적 패턴인식 기술인 개선된 마할라노비스 거리(IMD : Improved Mahalanobis Distance) 이론에 기반하여 변동성이 고려된 손상평가 기법을 개발하였다. 개발한 손상평가 기법에는 구조물의 고유한 정보에 기반한 Simulation 프로그램을 반영하여 다양한 외력에 따른 구조물의 무손상 응답을 출력하도록 하였다. 개발한 기법의 성능을 실험적으로 평가하기 위하여 모형 사장교를 대상으로 케이블 손상실험을 수행하였다. 그 결과, 변동성이 고려된 손상평가 기법은 외력에 따른 무손상 데이터를 자동으로 출력하고, 출력된 무손상 데이터와 계측된 손상 데이터의 분석을 통하여 케이블의 손상 위치를 판단할 수 있는 정보를 추출하는 성능을 보이는 것을 확인하였다.

• Structural Engineering and Mechanics
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• 제75권6호
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• pp.723-736
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• 2020

In this paper, acoustic emission (AE) and pattern recognition are utilized to identify the AE signal signatures caused by propagation of stress corrosion cracking (SCC) in a 304 stainless steel plate. The surface of the plate is under almost uniform tensile stress at a notch. A corrosive environment is provided by exposing the notch to a solution of 1% Potassium Tetrathionate by weight. The Global b-value indicated an occurrence of the first visible crack and damage stages during the SCC. Furthermore, a method based on linear regression has been developed for damage identification using AE data.

• Structural Engineering and Mechanics
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• 제75권3호
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• pp.295-309
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• 2020

The construction of Reinforced Concrete (R/C) buildings with unreinforced masonry infills is part of the traditional building practice in many countries with regions of high seismicity throughout the world. When these buildings are subjected to seismic motions the presence of masonry infills and especially their configuration can highly influence the seismic damage state. The capability to avoid configurations of masonry infills prone to seismic damage at the stage of initial architectural concept would be significantly definitive in the context of Performance-Based Earthquake Engineering. Along these lines, the present paper investigates the potential of instant prediction of the damage response of R/C buildings with various configurations of masonry infills utilizing Artificial Neural Networks (ANNs). To this end, Multilayer Feedforward Perceptron networks are utilized and the problem is formulated as pattern recognition problem. The ANNs' training data-set is created by means of Nonlinear Time History Analyses of 5 R/C buildings with a large number of different masonry infills' distributions, which are subjected to 65 earthquakes. The structural damage is expressed in terms of the Maximum Interstorey Drift Ratio. The most significant conclusion which is extracted is that the ANNs can reliably estimate the influence of masonry infills' configurations on the seismic damage level of R/C buildings incorporating their optimum design.