• Earthquakes and Structures
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• v.9 no.1
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• pp.257-279
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• 2015

The primary objective of this study is to summarize results from previous experimental tests on laboratory specimens of RC/steel frames with masonry infills, in order to develop fragility functions that permit the estimation of damage in typical non-structural components of RC frame buildings, as a function of attained peak interstory drift. The secondary objective is to derive loss functions for such non-structural components, which provide information on the probability of experiencing a certain level of monetary loss when a given damage state is attained. Fragility curves and loss function developed in this study can be directly used within the FEMA P-58 framework for the seismic performance assessment of RC frame buildings with masonry infills.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.04a
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• pp.789-794
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• 2008

The damage identification in a flexible system requires modal informations which is represented by FRF(Frequency response function) or modal parameters. In this paper, energy isoclines are introduced to access the prediction of fatigue damage on a flexible component exposed mainly to the exciting source rather than external forces. After deriving the concerned function, energy isoclines, from the investigation of the relationship between energy and damage, its practical application is explained by the simple uni-axial excitation test for the notched round bar.

• Smart Structures and Systems
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• v.9 no.1
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• pp.55-70
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• 2012

It is not easy to experimentally obtain the FRF (Frequency Response Function) matrix corresponding to a full set of DOFs (degrees of freedom) for a dynamic system. Utilizing FRF data measured at specific positions, with DOFs less than that of the system, as constraints to describe a damaged system, this study identifies parameter matrices such as mass, stiffness and damping matrices of the system, and provides a damage identification method from their variations. The proposed parameter identification method is compared to Lee and Kim's method and Fritzen's method. The validity of the proposed damage identification method is illustrated in a simple dynamic system.

• Advances in Traditional Medicine
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• v.4 no.2
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• pp.100-103
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• 2004

The plant Indigofera aspalathoides are used by a large number of tribes in India for the treatment of various hepatic disorder. The methanol extract of Indigofera aspalathoides (MEIA) was evaluated for its effect on carbontetrachloride $(CCl_{4})$ induced liver damage. Biochemical parameters such as serum glutamine oxaloacetate trasaminase (SGOT), serum glutamine pyruvate transaminase (SGPT), serum alkaline phosphatase (ALP), total serum protein (TP), thiobarbituric acid reactive substances (TBRS) and glutathione content of the liver were estimated to assess liver function and metabolism. Biochemical observations suggest that methanol extract of Indigofera aspalathoides (MEIA) significantly restored the liver function and metabolism towards normal condition in $CCl_{4}$-induced hepatic damage.

• Geomechanics and Engineering
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• v.9 no.1
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• pp.15-24
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• 2015

The porosity is often regarded as a linear function of fluid pressure in porous media and permeability is approximately looked as constants. However, for some scenarios such as unconsolidated sand beds, abnormal high pressured oil formation or large deformation of porous media for pore pressure dropped greatly, the change in porosity is not a linear function of fluid pressure in porous media, and permeability can't keep a constant yet. This paper mainly deals with the relationship between the damage variable and permeability properties of a deforming media, which can be considered as an exploratory attempt in this field.

• Journal of Yeungnam Medical Science
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• v.40 no.3
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• pp.225-232
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• 2023

Cognitive dysfunction is relatively less considered a complication of hypertension. However, there is sufficient evidence to show that high blood pressure in middle age increases the risk of cognitive decline and dementia in old age. The greatest impact on cognitive function in those with hypertension is on executive or frontal lobe function, similar to the area most damaged in vascular dementia. Possible cognitive disorders associated with hypertension are vascular dementia, Alzheimer disease, and Lewy body dementia, listed in decreasing strength of association. The pathophysiology of cognitive dysfunction in individuals with hypertension includes brain atrophy, microinfarcts, microbleeds, neuronal loss, white matter lesions, network disruption, neurovascular unit damage, reduced cerebral blood flow, blood-brain barrier damage, enlarged perivascular damage, and proteinopathy. Antihypertensive drugs may reduce the risk of cognitive decline and dementia. Given the high prevalence of dementia and its impact on quality of life, treatment of hypertension to reduce cognitive decline may be a clinically relevant intervention.

• Journal of the Earthquake Engineering Society of Korea
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• v.28 no.4
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• pp.215-222
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• 2024

Many older reinforced concrete (RC) buildings were constructed and designed with only gravity loads in mind. Columns in those buildings have insufficient reinforcement details that do not satisfy the requirements specified in current seismic design standards. This study aims to develop drift-based fragility functions for lightly RC columns. For this purpose, a database of 193 lightly RC columns was constructed to determine central and dispersion values of drift ratios for individual damage states. Additionally, to develop more accurate fragility functions of the columns, the failure mode of RC columns was incorporated into fragility functions. The classification procedure for column failure mode is proposed in this study. Fragility functions for older RC columns are constructed according to four different damage states. The main variables of the fragility functions proposed in this study are column properties and failure mode.

• Journal of Ocean Engineering and Technology
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• v.30 no.5
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• pp.341-348
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• 2016

The fatigue damage caused by wide band loadings has generally been predicted using fatigue damage models in the frequency domain rather than a rain-flow counting method in the time domain because of its computation cost. This study showed that these fatigue damage models can be simplified in the form of normalized fatigue damage as a function of the S-N curve slope and bandwidth parameters. Based on numerical simulations of various wide band spectra, it was found that fatigue damage models in the form of normalized fatigue damage with one S-N curve slope and two bandwidth parameters( α₁ , α₂ ) provided less reasonable fatigue damage. Therefore, an additional bandwidth parameter needs to be considered based on a sensitivity study using various neural networks, which proved that α_1-5 would be the dominant factor of a fatigue damage model as an additional bandwidth parameter.

• Journal of Advanced Marine Engineering and Technology
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• v.28 no.6
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• pp.993-999
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• 2004

The estimation of fatigue life at the design stage of membrane type LNG tank is very important in order to arrive at feasible and cost effective solutions considering the total lifetime of the tank. In this study, the practical procedure of fatigue life prediction by use of cumulative damage factors based on Miner-Palmgren hypothesis and probability density function has been shown with the corner region of Gaz Transport Membrane type LNG tank being used as an example. In particular the parameters of Weibull distribution that determine the stress spectrum are discussed. The main results obtained from this study are as follows: 1. The recommended value for the shape parameter of Weibull distribution for the LNG tank is 1.1 in case of using the direct calculation method proposed in this study. 2. The calculated fatigue life is influenced by the shape parameter of Weibull distribution and stress block. The safe fatigue design can be achieved by using higher value of shape parameter and the stress blocks divided into more stress blocks.

• Nuclear Engineering and Technology
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• v.31 no.3
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• pp.267-275
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• 1999

This paper deals with the industrial problem of thermal striping damage on the French prototype fast breeder reactor, Phenix and it was studied in coordination with the research program of IAEA. The thermomechanical and fracture mechanics evaluation procedure of thermal striping damage on the tee-junction of the secondary piping using Green's function method and standard FEM is presented. The thermohydraulic(T/H) loading condition used in the present analysis is the random type thermal loads computed by T/H analysis on the turbulent mixing of the two flows with different temperatures. The thermomechanical fatigue damage was evaluated according to ASME code section 111 subsection NH. The results of the fatigue analysis showed that fatigue failure would occur at the welded joint within 90,000 hours of operation. The assessment for the fracture behavior of the welded joint showed that the crack would be initiated at an early stage in the operation. It took 42,698.9 hours for the crack to propagate up to 5 mm along the thickness direction. After then, however, the instability analysis, using tearing modulus, showed that the crack would be arrested, which was in agreement with the actual observation of the crack. An efficient analysis procedure using Green's function approach for the crack propagation problem under random type load was proposed in this study. The analysis results showed good agreement with those of the practical observations.