Kim, Chobok;Heo, Juyeon;Hong, Jiyun;Yi, Kyongmyon;Park, Jungkyu;Shin, Changhwan
한국노년학
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v.40
no.2
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pp.325-340
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2020
Early diagnosis and intervention of dementia is critical to minimize future risk and cost for patients and their families. The purpose of this study was to develop and validate Figure-Copy Test(FCT), as a new dementia screening test, that can measure neurological damage and cognitive impairment, and then to examine whether the grading precesses for screening can be automated through machine learning procedure by using FCT imag es. For this end, FCT, Korean version of MMSE for Dementia Screening (MMSE-DS) and Clock Drawing Test were administrated to a total of 270 participants from normal and damaged elderly groups. Results demonstrated that FCT scores showed high internal constancy and significant correlation coefficients with the other two test scores. Discriminant analyses showed that the accuracy of classification for the normal and damag ed g roups using FCT were 90.8% and 77.1%, respectively, and these were relatively higher than the other two tests. Importantly, we identified that the participants whose MMSE-DS scores were higher than the cutoff but showed lower scores in FCT were successfully screened out through clinical diagnosis. Finally, machine learning using the FCT image data showed an accuracy of 73.70%. In conclusion, our results suggest that FCT, a newly developed drawing test, can be easily implemented for efficient dementia screening.
The electric submersible pump (ESP) has been operating in production wells around the world because of its high applicability and operational efficiency among artificial lift techniques. When operating an ESP in a reservoir, variables such as temperature, pressure, gas/oil ratio, and flow rate are factors that affect ESP performance. In particular, free gas in the production fluid is a major factor that reduces the life and operational efficiency of ESP. This study presents the flow loop system which can implement the performance and damage tests of ESP considering field operating conditions to quantitatively analyze the variables that affect ESP performance. The developed apparatus in an integrated system that can diagnose the failure and causes of ESP, and detect leak of tubing by linking ESP and tubing as one system. In this study, the flow conditions for stable operation of ESP were identified through single phase and two phase flow experiments related to evaluation for the performance of ESP. The results provide the basic data to develop the failure prediction and diagnosis program of ESP, and are expected to be used for real-time monitoring for optimal operating conditions and failure diagnosis for ESP operation.
Kim, Sun-Mee;Cho, Min-Kyung;Yu, Hak-Sun;Cha, Hee-Jae;Ock, Mee-Sun
Journal of Life Science
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v.19
no.9
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pp.1328-1332
/
2009
Anisakidosis is caused by anisakid nematodes (family Anisakidae) larvae which can cause not only direct tissue damage but also a severe allergic response related to excretory-secretion products. Lots of different species of anisakid larvae, including Anisakis simplex, Contracaecum, Goezia, Pseudoterranova, and Hysterothylacium, cause the anisakidosis. But it is difficult to diagnosis the species of larvae since the morphologies of larval anisakid nematodes are almost indistinguishable. In order to diagnosis the differential infections of larval anisakid nematodes, polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) of 18S rDNA - was conducted. Three major species of anisakid larvae including A. simplex, C.ontracaecum spp, and Goezia spp. were collected from mackerel (Scomber japonicus), mullet (Mugil cephalus), founder (Paralichthys olivaceus), eel (Astroconger myriaster) and red sea bream (Pagrus major). PCR amplified 18S rDNA from each species of anisakid larvae was digested with eight restriction enzymes including Taq I, Hinf I, Hha I, Alu I, Dde I, Hae III, Sau96 I, and Sau3A I. The original sizes of PCR amplified 18S rDNA were 2.0Kb in both anisakid larvaes and Goezia. Restrction enzymes including Hinf 1, Alu 1, Hha I, Dde 1 and Hae III cut differently and distinguished the A. simplex and Contracaecum type C'. However, Contracaecum type A showed two different restriction enzyme cutting patterns by Taq 1, Hinf I, Alu 1, and Dde 1. One of the patterns was the same as those of A. simplex, Contracaecum type C' and Goezia and the other was unique. These results suggest that PCR-RFLP pattern by Hinf 1, Alu 1, Hae I, Dde 1 and Hae III can be applied to differential diagnosis of human infection with A. simplex and Contracaecum type C'. Contracaecum type A needs further study of classification by morphological characteristics and genetic analysis.
Journal of Korean Society of Disaster and Security
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v.12
no.3
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pp.25-34
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2019
Modern disasters prevent accidents in advance and recover after accidents are very important. Our government's current response to these accidents is not appropriate. As for disaster management so far, it has been the center of disaster response and recovery efforts, and has been led by the government against it. The reality is that most private organizations and agencies have only subsidized government disaster management agencies. Korea is no longer a safe zone for earthquakes. Now for the establishment of effective disaster management system for earthquakes in the diagnosis is very urgent and the problems of the operational disaster management, which the problems of the nation.Policies to improve academic efforts to seek alternative proposal is also at a time when volume can be said to be very big need to mine. This study from 2016 to 2019, about the earthquake that took place between National Statistical Office, based on analysis of data to. First of all, research 1: What was the government's plan on Pohang earthquake? The results showed that the residents' evacuation of Pohang was important in the Pohang earthquake, but for the sake of students' safety, they were directly assigned to the test site to cope with the emergency situation. Therefore, the research and analysis shows that the nation should continue to think about the causes and responses of the damage at the disaster site and strive to develop technologies and methods to minimize the damage.
This study aims to find out the standardized test criteria regarding patients with the anterior cruciate ligament damage by identifying the degree of the flexion gap of femur and tibia upon bending of the anterior cruciate ligament in order to carry out the accurate test of such impairment. On the standardized test method and judgement criteria upon the anterior cruciate ligament test using Telos, it has been shown that there was no significant difference in the results according to the position of a fixed roller in the anterior cruciate ligament test for normal patients. However, in a test for patients who had undergone the anterior cruciate ligament reconstruction, it has been shown that the measured values of the anterior cruciate ligament tended to be pushed when the position of a fixed roller was less than 1cm in the test according to the position of a fixed roller of Telos (less than 1cm, more than 3cm), and this was statistically significant. The anterior cruciate ligament test (knee stress test) is a limited method used in orthopedics and rehabilitation medicine, and there have been no standardized test guidelines available yet although numerous ligament measurement tests have been performed. In addition, since the measured values are often different depending on testers even on the test that is expected to give the same result, the reproducibility of the test is still low. Accordingly, it is considered that the criteria for the anterior cruciate ligament test need to be established, and this would contribute to the accuracy of the diagnosis through the accurate test and standardized measurements.
Lee, Jang Jon;Ahn, Ji Yoon;Yoo, Young Mi;Lee, Kyeong Min;Han, Min Su
Journal of Conservation Science
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v.33
no.6
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pp.431-442
/
2017
The purpose of this study is to reveal that coloring status and the degree of damage and the kinds of pigments used in large buddhist painting (Gwaebultaeng) of Tongdosa temple using a scientific analysis methods. It was observed that the physical damage patterns of the Gwaebultaeng were folding, lifting, fading, and peeling. Lead red, cinnabar and organic pigments were used as red pigments. Malachite and atacamite were used as green pigments, azulite and lazulite were blue pigments, lead white and talc were white pigment. It is estimated that overlapping organic pigments on the lead white were used as the yellow pigment and carbon was the black pigment. Through the analysis of the particle status of the pigments, it was confirmed that different types of raw materials were used for the green pigment, and the crystal form was easily distinguishable. Also, the dark blue color and the light blue color differed from each other depending on the size and shape of the raw material particles. Yellow and purple colors were organic pigments which did not have a graininess. The yellow and purple colors were organic pigments free from the graininess, and the pigments of dark red pigments was found to be mixed with the orange color pigments and carbon particles.
There are two opinions on the legal characteristics of damages for non-pecuniary loss, a private sanctions theory and complementary function of damages for non-pecuniary loss, briefly. There is a close connection between the legal characteristics and the function of damages for non-pecuniary loss. The functions of damages for non-pecuniary loss are consist of satisfaction, prevention( sanctions) and complementation. Several cases of medical injury relief reported to Korea Comsumer Agency are categorized as follows, 1) cases of death after having an operation, 2) diagnosed with disability after a medical accident, 3) extended damages happening related to delayed diagnosis, 4) et cetera(a plastic surgery, a treatment with oriental medicine), and the damages for non-pecuniary loss in respect to each cases are examined. In the case of occurring death or disability, Korea Comsumer Agency has set up guidelines for assessment of damages for non-pecuniary loss by classifying into major and collateral violation for a duty of care. Furthermore, the damages for non-pecuniary loss in the case of all sorts of cancers, are assessed in accordance with the degree of responsibility subsequent to dividing cancer into good and poor prognosis. When it comes to a complementary function of damages for non-pecuniary loss in the actual work, it is hard to assess the damages as it is difficult to objectify non-pecuniary loss, such as emotional distress. Though compensation for damages is major legal characteristics of consolation money, preventing a damage(private sanctions) through consolation for a victim or sanctions against an assailant also has great significance. Therefore, it is necessary to approach flexibly for mutual agreement by considering specialty( concrete facts) of individual issue thoroughly. If considering this aging society that limits the possible age for work to 60 years old, it is needed to have a complementary function of consolation money in mind not to make it less meaningful for victims due to small sum of consolation money.
Nervous necrosis virus (NNV) contains a bi-segmented viral genome, RNA1 (3.4 kb, RdRp), and RNA2 (1.4 kb, capsid protein) in a small particle (25 nm). Despite its extremely compact size, NNV has caused serious damage by infecting approximately 120 fish species worldwide since it was first reported in the late 1980s. In order to minimize the damage caused by NNV infection and develop effective vaccines, it is necessary to understand the intra cellular signaling system according to NNV infection. NNV infection induces cell cycle arrest at the G1 phase via the p53-dependent pathway to use the cellular system for its replication. Otherwise, host cells recognize NNV infection through the RIG-1-like receptor (RLR) signaling pathway to control the virus and infected cells, and then ISGs required for antiviral action are activated via the IFN signaling pathway. Moreover, apoptosis of infected cells is triggered by the unfolded protein response (UPR) through ER stress and mitochondria-mediated cell death. Cell signaling studies on the NNV infection mechanisms are still at an early stage and many pathways have yet to be identified. Understanding the various disease-specific cellular signaling systems associated with NNV infection is essential for rapid and accurate diagnosis and vaccine development.
Journal of The Korean Society of Agricultural Engineers
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v.62
no.4
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pp.75-86
/
2020
The purpose of this study is to develop a technology for estimating rice growth and damage effect according to bacterial leaf blight using UAV multi-spectral imagery. For this purpose, we analyzed the change of aerial images, rice growth factors (plant height, dry weight, LAI) and disease effects according to disease occurrence by using UAV images for 3 rice varieties (Milyang23, Sindongjin-byeo, Saenuri-byeo) from 2017 to 2018. The correlation between vegetation index and rice growth factor during vegetative growth period showed a high value of 0.9 or higher each year. As a result of applying the growth estimation model built in 2017 to 2018, the plant height of Milyang23 showed good error withing 10%. However, it is considered that studies to improve the accuracy of other items are needed. Fixed wing unmanned aerial photographs were also possible to estimate the damage area after 2 to 4 weeks from inoculation. Although sensing data in the multi-spectral (Blue, Green, Red, NIR) band have limitations in early diagnosis of rice disease, for rice varieties such as Milyang23 and Sindongjin-byeo, it was possible to construct the equation of infected leaf area ratio and rice yield estimation using UAV imagery in early and mid-September with high correlation coefficient of 0.8 to 0.9. The results of this study are expected to be useful for farming and policy support related to estimating rice growth, rice plant disease and yield change based on UAV images.
Lee, Hee Young;Lee, Jung Hun;Jeon, Hyeok Jin;Kim, Ho Jung;Kim, Sang Chul;Youn, Young Han;Lee, Kang Hyun
Journal of Auto-vehicle Safety Association
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v.10
no.4
/
pp.7-12
/
2018
Injury mechanisms of lower extremity injuries in motor vehicle accidents are focused on fractures, sprains, and contusions. The purpose of this study is to evaluate the analysis of lower extremity injury mechanism in occupant motor vehicle accident by using Hospital Information System (HIS) and reconstruction program, based on the materials related to motor vehicle accidents. Among patients who visited the emergency department of Wonju Severance Christian Hospital due to motor vehicle accidents from August 2012 to February 2014, we collected data on patients with agreement for taking the damaged vehicle's photos. After obtaining the verbal consent from the patient, we asked about the cause of the accident, information on vehicle involved in the accident, and the location of car repair shop. The photos of the damaged vehicle were taken on the basis of front, rear, left side and right side. Damage to the vehicle was presented using the CDC code by analytical study of photo-images of the damaged vehicle, and a trauma score was used for medical examination of the severity of the patient's injury. Among the 1,699 patients due to motor vehicle crashes, 88 (5.2%) received a diagnosis of lower extremity fracture and 141 (8.3%) were the severe who had ISS over 15. Nevertheless during 19 months for research, it was difficult to build up in-depth database about motor vehicle crashes. It has a limitation on collecting data because not only the system for constructing database about motor vehicle crash is not organized but also the process for demanding materials is not available due to prevention of personal information. For accurate analysis of the relationship between occupant injury and vehicle damage in motor vehicle crashes, build-up of an in-depth database through carrying out various policies for motor vehicle crashes is necessary for sure.
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