• Tunnel and Underground Space
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• v.25 no.4
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• pp.332-340
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• 2015

Ground subsidence occurring in mine area can cause an enormous damage of loss of lives and properties, and a systematic survey should be conducted a series of field investigation and ground stability analysis in subsidence area. This study describes the results from field investigation and ground stability analysis in a limestone mine located in Cheongwon-gun, Chungcheongbuk-do, Korea. Rock mechanical measurements and electrical resistivity surveys are applied to obtain the characteristics of in-situ rock masses and the distribution patterns of subsurface weak zone, and their results are extrapolated in numerical analysis. From the field investigation and stability analysis, it is concluded that the subsidence occurrence in this limestone mine is caused mainly by subsurface limestone cavities.

• Journal of environmental and Sanitary engineering
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• v.19 no.3 s.53
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• pp.71-80
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• 2004

The purpose of this study was to find the relationship between osteoporosis and various factors such as general personal background, physical activity, menstruation, daily life and dietary habit. The following are the results of this study: 1. In the relationship of osteoporosis status with general personal background, the risk of osteoporosis increased with age. Active women with higher education, high income and jobs tended to have less risk of osteoporosis. Women with earlier menarche had a tendency of having thicker bone mineral density. 2. As for disease related to bone mineral density, stomach disease, thyroid, bone damage, and bad teeth conditions were significant factors affecting bone mineral density. Women with those diseases and family history of osteoporosis were more likely to have osteoporosis. 3. In relation to food intake regular diet of dairy products, anchovy, or meat showed significantly less risk of osteoporosis. 4. In relation between dietary habits and bone mineral density, unbalanced diet had statistically less probability of osteoporosis. It is important for genetically disposed women to prevent osteoporosis in advance by considering acquired factors like life-style and medication.

• Toxicological Research
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• v.22 no.2
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• pp.87-93
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• 2006

The KFDA (Korea Food & Drug Administration) has performed a collaborative toxico-genomics project since 2003. Its aim is to construct a toxicologenomic database of 12 hepatotoxic compounds from mice livers. Phenylbutazone which is non-steroidal anti-inflammatory drug was assigned. It was administered at low (0.0238 mg/kg) and at high (0.238 mg/kg) dose (5 mice per group) orally to the postnatal 6 weeks ICR mice, then the serum and liver were collected at the indicated time (6, 24 and 72 h) after administration. Serum biochemical markers for liver toxicity were measured and histopathologic studies also were carried out. The gene expression profiling was carried out by using Applied Biosystems 1700 Full Genome Expression Mouse. The 2-way ANOVA was used to find genes that reflected phenylbutazone-induced acute toxicity or dose-dependant changes. By self-organization maps (SOM), we identified groups with unique gene expression patterns, some of them are supposed to be related to phenylbutazone induced toxicity, including lipid metabolism abnormality, oxidative stress, cell death and cytoskeleton destruction.

• Journal of the Korean Society of Marine Environment & Safety
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• v.6 no.2
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• pp.1-15
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• 2000

In world trade, the vessel traffic in major routes has been congested due to the rapid increase of cargoes and shipping tonnages. The patterns of vessel traffic have also been complicated and diversified. Therefore it was necessary that the Vessel Traffic Service(VTS) should be established in order to enhance the safety of navigation, to prevent the loss of life and damage to the environment. The first advanced radar surveillance system(LevelIII-VTS) was introduced in Pohang, Korea in 1993 and in 13 other ports later. While the hardware of Korea VTS is equal to that of an advanced country, the software, specially the operation manual, the recruitment and education of VTS operator, and the VTS service area is behind that of Russia, USA, Germany, Hong Kong, Singapore and others. After researching and investigating. the VTS equipment and service area of many countries, and analyzing the IMO regulations relevant to VTS and the traffic pattern and accident of Pohang port, the most efficient VTS service area should be established in Pohang. According to the analysis of the preceding studies and research on VTS, the worldwide VTS areas are recognized under the following conditions: First, the service area should be extended over at least radar coverage taking into account of traffic flow, traffic density, the degree of danger to navigation and harbour condition in order to provide all possible services. Second, the established service area should be subdivided and systematized to render reliable VTS services, such as the allocation of VHF frequency and reporting procedure in each area. In conclusion, the VTS service area of Pohang must be established and operated over 10 miles from shore(radar site) covering the radar coverage, so as to include the area of traffic congestion and high density traffic flow.

• Journal of the Korean Professional Engineers Association
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• v.23 no.2
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• pp.81-93
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• 1990

The blasting to construct subways in Seoul, Korea. have often increased complaints of ground vibration. In order to prevent the damage to structures, it was necessary to predict the level of blasting induced vibration and to determine the maximum charge weight per delay within a allowable vibration level. A total of 109 blasts were recorded at ten sites. Blast-to-structure distances ranged from 8 to 84.2 meter, where charge weight varied from 0,1125 to 7.85 kg per delay. The data from blast were studied to determine the effect of explosives type on the vibration constants(k). Vibration constants were also analyzed in terms of compressive strength of rock and blasting patterns.

• The Journal of the Korea Contents Association
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• v.6 no.8
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• pp.57-67
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• 2006

The motion effect of animation can be maximized by using the intended number of frame(flickering phenomena) responding to the viewer's perception in the production processes. But, the high contrast of chroma in a color arrangement can cause very dangerous situation if a particular effect(scheduled number of frame for the intended rapid flickering in a zoom-in scene of the warning light of police car and the traffic light) or a excessive visual stimulus is tried. The danger of flickering phenomena is defined as 'Flash Nervousness Attack Symptom' in medical terminology, which has received wide attention because the damage to the viewers of Pocket Monster was very serious in Japan. Producing a piece of animation work, the quality control of colors is important but the color setting considering the psychological aspects, the danger of repetitive flickering of flashes and patterns in image effect are more serious, so these factors should be checked in the production stages. After investigating the domestic and foreign prescriptions including the guidelines for animation production technique in Japan, a solution to reduce the danger of flickering phenomena of color and light was suggested through statistical comparative analysis with the test results.

• Journal of Nutrition and Health
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• v.36 no.5
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• pp.491-499
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• 2003

Selenium is a strong antioxidant trace mineral, scavenging free radicals. The prevalence of chronic degenerative diseases is increasing in Korean adults with increasing age. The increased cell damage from free radicals has been implicated in the etiology of these diseases, and evidence is accumulating that the low selenium status that comes with advanced aged is involved in the prevalence of age-associated diseases. However, little is known about the selenium status of Koreans, its age-related change and its relationship to dietary nutrient intake. In this study, the serum selenium levels of healthy adult females according to life cycle and its association with blood albumin levels and nutrient intake were examined. Serum selenium level was measured with the Huwo research reactor using the neutron activation analysis method (NAA). The overall proportion of women with selenium deficiency, serum selenium concentrations below 7.0 $\mu\textrm{g}$/dl, was 9.4%. The average serum selenium levels were 12.39 $\mu\textrm{g}$/dl, 9.45 $\mu\textrm{g}$/dl and 9.16 $\mu\textrm{g}$/dl in the young adult, middle-aged and elderly groups, respectively, showing a reduction of selenium status with advancing age. Selenium deficiency was seen only in the elderly group. Generally, serum selenium levels positively or negatively correlated with nutrient intake, but these association patterns differed depending on the age. The nutrients that showed positive correlations with selenium levels were proteins and phosphate in the young adult group (p < 0.05, p < 0.05), and total calcium, potassium and vegetable-origin calcium in the middle-aged group. Vitamin C and fiber were the negative correlated nutrients with serum selenium levels in the elderly group (p < 0.05, p < 0.05). Multiple stepwise regression analysis of the determining factors responsible for selenium status showed that age and serum albumin levels were important factors which explained up to 26.9% variances in serum selenium levels. The average selenium concentrations of Korean adult female subjects were above the deficiency levels in all three age groups. There was a tendency toward decreasing selenium levels as the age of the subjects increased. The factors with the strongest in-fluence on selenium status in healthy adult Korean females were age and serum protein status. (Korean J Nutrition 36(5): 491~499, 2003)

• YAKHAK HOEJI
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• v.49 no.4
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• pp.317-322
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• 2005

Isoflavones are reported to playa role in menopausal women as a phytoestrogen, which can replace estradiols in hormone replacement therapy (HRT). Recently; due to the risk of breast cancer by HRT, phytoestrogens (e.g. isoflavones) have been focused as an alternative therapy in menopause. In the study, we investigated whether isoflavones derived from Sophorae fructus (SISO) have more benefit than that of soybean isoflavones in estrogen deficient rats. We found that SISO effectively controled $H_2O_2$ comparing with the baseline (p<0.01 vs. post value of OVX-Cont), and the blood sugar and weight were also controlled with decreasing patterns. Additionally, in LDH assay for cytoprotective effect in Neuro-2a cell line, SISO protected cells from the damage by SNAP (p<0.05). In conclusion, SISO may have more beneficial effect in enhancing the menopausal signs than that of soybean isoflavones and the cytoprotective effect in neuron cells suggests that SISO can play a certain role in neuroprotection after menopause.

• Journal of the Korea Society of Computer and Information
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• v.19 no.1
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• pp.85-94
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• 2014

This paper studied the detection technique using file DNA-based behavior pattern analysis in order to minimize damage to user system by malicious programs before signature or security patch is released. The file DNA-based detection technique was applied to defend against zero day attack and to minimize false detection, by remedying weaknesses of the conventional network-based packet detection technique and process-based detection technique. For the file DNA-based detection technique, abnormal behaviors of malware were splitted into network-related behaviors and process-related behaviors. This technique was employed to check and block crucial behaviors of process and network behaviors operating in user system, according to the fixed conditions, to analyze the similarity of behavior patterns of malware, based on the file DNA which process behaviors and network behaviors are mixed, and to deal with it rapidly through hazard warning and cut-off.

• Journal of Haehwa Medicine
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• v.13 no.1
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• pp.27-38
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• 2004

Saam acupuncture has an evident principles of prescription based on acupuncture tonification and purgation of Nan-gyeong but many prescriptions of Saam acupuncture are not typical patterns. Therefore it is difficult to understand principles of those prescriptions. Understanding the principles of any prescription means understanding the physiology and pathology of that prescription and it have an important role in selecting the best prescription and taking the most effective treatment. This paper studies principles of prescriptions of the king fire and the premier fire. The theoretical authorities of analysis are Nan-gyeong, works of Joo dan-gye and Li dong-won and Uihakimmun. The damage of fire to mentality is very intensive and severe. The prescriptions of the king fire and premier fire have a good effect on diseases by fire. The fire of human body are two types, the king fire and the premier fire but the water of human body is only one and then inferior to fire. The fire superior to the water is unstable and the fire influences rapidly and intensively on four elements, wood, earth, metal, water. So the control of the water is the key to treat the disease by fire. Considering the attack and the treatment of disease, heart and liver are attacked with a disease by fire in its early stage and kidney and lung are the key to treatment. Consequently the pathology of the disease by fire is corresponding to the theory- Yang Sufficient, Yin Deficient- of Joo dan-gye. It seems that the theory of Joo dan-gye influenced on the medical theory of Saam Acupuncture. On that account I believe that the study of medical theories of the Geum and Won Dynasty that various medical theories appeared is very available.