• Smart Structures and Systems
• /
• v.3 no.3
• /
• pp.263-280
• /
• 2007

In this paper, an improved GA-based damage detection algorithm using a set of combined modal features is proposed. Firstly, a new GA-based damage detection algorithm is formulated for beam-type structures. A schematic of the GA-based damage detection algorithm is designed and objective functions using several modal features are selected for the algorithm. Secondly, experimental modal tests are performed on free-free beams. Modal features such as natural frequency, mode shape, and modal strain energy are experimentally measured before and after damage in the test beams. Finally, damage detection exercises are performed on the test beam to evaluate the feasibility of the proposed method. Experimental results show that the damage detection is the most accurate when frequency changes combined with modal strain-energy changes are used as the modal features for the proposed method.

• Smart Structures and Systems
• /
• v.24 no.4
• /
• pp.475-490
• /
• 2019

The detection of structural damage without a priori information on the healthy state is challenging. In order to address the issue, the study presents a baseline-free approach to detect damage in beam structures based on an actual influence line. In particular, a multi-segment function-fitting calculation is developed to extract the actual deflection influence line (DIL) of a damaged beam from bridge responses due to a passing vehicle. An intact basis function based on the measurement position is introduced. The damage index is defined as the difference between the actual DIL and a constructed function related to the intact basis, and the damage location is indicated based on the local peak value of the damage index curve. The damage basis function is formulated by using the detected damage location. Based on the intact and damage basis functions, damage severity is quantified by fitting the actual DIL using the least-square calculation. Both numerical and experimental examples are provided to investigate the feasibility of the proposed method. The results indicate that the present baseline-free approach is effective in detecting the damage of beam structures.

• Toxicological Research
• /
• v.17 no.4
• /
• pp.249-253
• /
• 2001

Fumonisin B1, a mycotoxin, is thought to induce esophageal cancer in humans and apoptosis in animal cells by inhibiting ceramide synthase. Dumonisin Bl may also generate reactive oxygen species directly or indirectly, leading to DNA damage and lipid peroxidation. In this study, a DNA fragmentation assay, dichlorofluorescein (DCF) analysis, and single cell gel electrophoresis (SCGE) were used to investigate the involvement of cellular free radicals, specifically hydrogen peroxide, in the DNA damaging activity of fumonisin B1. From an in vitro DNA fragmentation assay, E. coli DNA, damage by fumonisin Bl was increased by the addition of superxide dismutase (SOD) and decreased by catalase. SCGE and DCF analysis in vivo showed that the nuclear DNA damage and intracellular free radicals in cultured rat hepatocytes treated with fumonisin B1 were increased with the concentration of fumonisin Bl . DNA damage and free radical generation were inhibited by the addition of catalase. Fumonisin Bl , in the presence of SOD, produces hydrogen peroxide causing oxidative DNA damage and protein malfunction, leading to genotoxicity and cytotoxicity of the toxin.

• Smart Structures and Systems
• /
• v.12 no.2
• /
• pp.181-207
• /
• 2013

In this paper, a statistical reference-free real-time damage detection methodology is proposed for detecting joint and member damage of truss bridge structures. For the statistical damage sensitive index (DSI), wavelet packet decomposition (WPD) in conjunction with the log likelihood ratio was suggested. A sensitivity test for selecting a wavelet packet that is most sensitive to damage level was conducted and determination of the level of decomposition was also described. Advantages of the proposed method for applications to real-time health monitoring systems were demonstrated by using the log likelihood ratios instead of likelihood ratios. A laboratory truss bridge structure instrumented with accelerometers and a shaker was used for experimental verification tests of the proposed methodology. The statistical reference-free real-time damage detection algorithm was successfully implemented and verified by detecting three damage types frequently observed in truss bridge structures - such as loss of bolts, loosening of bolts at multiple locations, sectional loss of members - without reference signals from pristine structure. The DSI based on WPD and the log likelihood ratio showed consistent and reliable results under different damage scenarios.

• Journal of Advanced Research in Ocean Engineering
• /
• v.1 no.4
• /
• pp.198-210
• /
• 2015

This paper presents the damage assessment of a free-fall dropped object on the seabed. The damage to a dropped object totally depends on the relationship between the impact energy and the soil strength at the mudline. In this study, unexpected dropping scenarios were first assumed by varying the relevant range of the impact velocity, structure geometry at the moment of impact, and soil strength profile along the penetration depth. Theoretical damage assessments were then undertaken for a free-fall dropping event with a fixed final embedment depth for the structure. This paper also describes the results of a three-dimensional large deformation finite element analysis undertaken for the purpose of validation. The analyses were carried out using the coupled Eulerian-Lagrangian approach, modifying the simple elastic-perfectly plastic Tresca soil model. The validation exercises for each dropping scenario showed good agreement, and the present numerical approach was capable of predicting the behavior of a free-fall dropped object.

• Biomedical Science Letters
• /
• v.5 no.1
• /
• pp.51-58
• /
• 1999

To evaluate an effect of liver damage on the dermal oxygen free radical metabolizing enzyme activities, the $CCl_4$ (0.1 ml/ 100 g body wt., 50% $CCl_4$ in olive oil) was intraperitoneally given to the rats every other day for 2 weeks. Based on the histopathological findings, liver weight (%), serum alanine aminotransferase, xanthine oxidase activities and hepatic lipid peroxide contents, the animals were induced severe liver damage. In the present liver damaged animal, all the activities of dermal scavenging enzymes such as superoxide dismutase, catalase and glutathione peroxidase were significantly decreased compared with central. And under the cytochemical electron microscopy the more coarse granules of cerrous perhydroxide were found compared with the control. In conclusion, the $CCl_4$-induced liver damage may influence upon the activities of some dermal oxygen free radical scavenging enzymes.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 2006.04a
• /
• pp.459-466
• /
• 2006

The objective of this study is to improve the accuracy of damage detection using natural frequency and modal strain energy. The following approaches are used to achieve the goal. First, modal strain energy is introduced and newly GA-based damage detection technique using natural frequency and modal strain energy is proposed. Next, to verify efficiency of the proposed technique, damage scenarios for free-free beams are designed and the vibration modal tests as damage cases are conducted. Finally, feasibility of proposed technique is verified in comparison with a GA-based damage detection technique using natural frequency and mode shape.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 2007.04a
• /
• pp.43-48
• /
• 2007

In this study, an ANN-based damage detection algorithm using acceleration signals is developed for alarming locations of damage in beam-type structures. A new ANN-algorithm using output-only acceleration responses is designed for damage detection in real time. The cross-covariance of two acceleration signals measured at two different locations is selected as the feature representing the structural condition. Neural networks are trained for potential loading patterns and damage scenarios of the target structure for which its actual loadings are unknown. The feasibility and practicality of the proposed method are evaluated from laboratory-model tests on free-free beams for which accelerations were measured before and after several damage cases.

• Preventive Nutrition and Food Science
• /
• v.14 no.4
• /
• pp.277-282
• /
• 2009

The antioxidant potency of methanolic extract of Duchesnea indica (MDI; Indian strawberry) was investigated by employing various established in vitro systems, such as total phenolic content, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, reducing power assay, metal chelating assay, superoxide radical scavenging activity and protective ability of DNA damage and protein oxidation. MDI inhibited metal chelating by 75.57% at 2 mg/mL, scavenged 50% DPPH free radical at 29.13 ${\mu}$g/mL, and eliminated approximately 46.21% superoxide radical at the concentration of 1 mg/mL. In addition, MDI showed strong ability on reducing power, DNA damage protection and protein oxidation protection. Overall, results suggested that MDI might be beneficial as a potent antioxidant and effectively employed as an ingredient in food applications.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2008.10a
• /
• pp.1323-1324
• /
• 2008

We developed the Hyper-thermal Neutral Beam (HNB) sputtering process as a plasma damage free process for ITO top anode deposition on inverted Top emission OLED (ITOLED). For examining the effect of the HNB sputtering system, Inverted Bottom emission OLEDs (IBOLED) with ITO top anode electrode were fabricated; the characteristics of IBOLED using HNB sputtering process shows significant suppression of plasma induced damage.