• Journal of The Korean Society of Grassland and Forage Science
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• v.31 no.4
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• pp.371-382
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• 2011

The aim of the present study was to investigate the relationship between climates, growth characteristic and yield of silage corn at Hanwoo Experiment Station, National Institute of Animal Science, Daegwallyeong in Gangwon Province located at altitude of 760 m, from 2009 to 2010. The mean minimum temperature was $12.29^{\circ}C$ from seeding to harvest in 2009, $14.30^{\circ}C$ in 2010, the mean maximum temperature was $21.66^{\circ}C$, $23.48^{\circ}C$, respectively. The mean temperature was $16.85^{\circ}C$ in 2009 and $18.55^{\circ}C$ in 2010, respectively. Duration of sunshine was 711.3 hours in 2009 and 663.8 hours in 2010, and precipitation was 893.8 mm in 2009 and 752.1 mm in 2010, respectively. In 2009, for all Kwangpyeongok, Gangdaok, Cheonganok, Cheongsaok, Pyeonganok, the early growth was good with 1.2, while in 2010 the growth for Pyeonganok was good with 1.3 comparing to others, which showed worse growth than in the previous year with 2.4~3.0. There was significant difference in the ear height between 2009 and 2010, showing mean value of 85.8 cm and 105 cm for all the species in 2009 and in 2010, respectively (p<0.001). In 2010, stem diameter for all the species were larger, and there was significant difference in mean value of the diameter between 2009 and 2010 (p<0.001). There was significant difference in the plant height and ear height between 2009 and 2010, showing 200 cm and 258 cm in 2009 and 2010, respectively (p<0.001). There was significant difference in the average days to silk, showing 103.8 days in 2009, 90 days in 2010, respectively (p<0.001). There was no lodging or disease-insect damage in all hybrid silage corn in both 2009 and 2010. The mean ear rates were 23.4% in 2009, but almost doubled, 52.1%, in 2010. There was significant difference in fresh yield between the two years, showing 54,611 kg/ha in 2009 and 78,733 kg/ha in 2010, respectively (p<0.001). Dry matter yields were higher in 2010 than in 2009. TDN yields of Gangdaok and Cheonganok were higher in 2009, whereas that of Cheongsaok and Pyeonganok were higher in 2010. Crude protein contents were higher in 2010 than in 2009 for all the species.

• Journal of The Korean Society of Grassland and Forage Science
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• v.32 no.3
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• pp.209-220
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• 2012

Most oats are used for livestock feed in the world. This experiment was conducted at Iksan city of Korea from 2007 to 2008. The objective of this study was to select eminent oat (Avena sativa L.) cultivars with high-yielding and a quality for forage adaptable in each planting seasons. Experimental design was split-plot design with three replications. A split plot design was used with seeding date on the main plots and other treatments fully randomized in sub-plots. A factorial arrangement of treatments included three different ecotypes cultivars, winter type (Sanmhan, Donghan and Chohan), summer type (High-speed, Darkhorse, and Swan), and naked oats near to spring type (Daeyang, Choyang, and Sunyang) and twelve seeding dates (twice a month from March to November). Plant height, dry matter yield, and percent TDN was significantly affected by seeding dates, cultivars, and the interaction of cultivars ${\times}$ seeding dates. There was a decrease in plant height, dry matter yield, and percent total digestible nutrients (TDN) as seeding was delayed from early March to late June and it also from early September to early November. The winter type oat cultivars such as Samhan, Donghan, and Chohan adapted to fall seeding and early summer harvest, while summer type cultivars such as High-speed, Darkhorse, and Swan showed high productivity either to summer seeding and mid-fall harvest or to spring seeding and early summer harvest. Naked type cultivars, Choyang and Daeyang, showed high forage yield by spring and summer seeding except for fall seeding because of cold damage. Summer type oat cultivars such as High-speed, Darkhorse, and Swan can supplement high forage production in spring. TDN yield showd the most at seeding in October 10 (780 kg $10a^{-1}$), followed at seeding in March 23 (627 kg $10a^{-1}$).

• Journal of Life Science
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• v.27 no.9
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• pp.975-985
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• 2017

To investigate the beneficial effects of an agar gel mask (AGM) on UV-induced photoaging, SKH-1 hairless mice were treated with a topical application of AGM and an AGM dipped in essence (AGMdE). The mice were divided into an no radiation group, UV + AGM, UV + AGMdE, and UV + vehicle (PBS) treatment groups. Alterations in skin wrinkles, skin phenotype, histological structures, oxidative status, and toxicity were then evaluated during 4 weeks of exposure. The topical application of AGM and AGMdE inhibited wrinkle formation, suppressed the erythema index, prevented transepidermal water loss, and enhanced skin hydration. In addition, epidermal thickness recovered to a similar level as that in the no irradiation group in the UV + AGM and UV + AGMdE treatment groups compared with the UV + vehicle (distilled water) group. Furthermore, the expression levels of matrix metalloproteinase-1 (MMP-1) and tyrosinase were reduced in the UV + AGM and UV + AGMdE treatment groups, although the highest level varied. Moreover, superoxide dismutase (SOD) activity was significantly lower in the UV + AGM and UV + AGMdE treatment groups as compared with the UV + vehicle group. No significant alterations induced by most toxic compounds were measured in serum biochemical markers and liver and kidney histological features of the UV + AGM and UV + AGMdE treatment groups. These results suggest that AGM may protect against skin aging by regulating skin morphology, histopathological structures, and oxidative conditions.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.6
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• pp.674-682
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• 2009

This study was designed to examine the effects of Compositae plants on plasma glucose and lipid levels in streptozotocin (STZ) induced diabetic rats. Sprague-Dawley rats were randomly assigned to 5 groups: normal, STZ-control and three experimental groups [Artemisia iwayomogi (A. iwayomogi), Atractylodes lancea (A. lancea), and Taraxacum mongolicum (T. mongolicum)]. Normal and STZ-control group were fed an AIN-93 diet and three experimental groups were each fed a modified diet containing 10% compositae powder for 4 weeks. The plasma glucose levels at 4 weeks of A. iwayomogi, A. lancea, and T. mongolicum groups were significantly lower than STZ-control group. The A. iwayomogi and A. lancea groups had significantly suppressed hypertrophy of liver and kidney. The hematocrit levels of A. lancea and T. mongolicum group were significantly lower than STZ-control groups. The total cholesterol and triglyceride levels and atherogenic index (AI) of A. lancea group were significantly lower than STZ-control group. Intake of Compositae plants may be effective in antihyperglycemia by lowering blood glucose levels. The A. iwayomogi, A. lancea, and T. mongolicum can be beneficial for the diabetic complications and damage from the lipid peroxidation.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.11
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• pp.1533-1543
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• 2016

The anti-stress effects of Punica granatum L. (family Lythraceae, PG) on $H_2O_2$/corticosterone (CORT)-induced stress in cells and sleep-deprived rats were investigated. The PG extract showed neuroprotective effects in SH-SY5Y cells against $H_2O_2$/CORT-induced stress. Sleep deprivation led to behavioral, hormonal, and biochemical alterations in the animal model. The effects of P. granatum on physiological, behavioral, and biochemical parameters aggravated by sleep deprivation were investigated. Sleep deprivation impaired physiological (survival, body weight, and drowsiness scores) and behavioral (rotarod, passive avoidance, hot hyperalgesia, and Y maze) parameters as well as biochemical factors (cortisol, serotonin, dopamine, testosterone, and growth factor I contents in serum). These parameters were significantly recovered by PG extract in a concentration-dependent manner. The PG extract also enhanced catalase, superoxide dismutase, and non-enzymatic antioxidative activities such as glutathione compared to sleep-deprived rats. On the basis of these results, our findings suggest that Punica granatum prevents impairment of body functions induced by sleep deprivation and related oxidative damage.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.5
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• pp.561-568
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• 2009

To investigate the effects of garlic and medicinal plants extracts (GP) on liver function and lipid metabolism of rat administered with ethanol chronically, Sprague-Dawly male rats were fed with a basial diet (Normal), a basial diet plus ethanol (Control, 10 mL of 20% ethanol/kg b.w/day), a control diet plus 0.5% garlic and 1.0% medicinal plants extracts (GP-I), and a control diet plus 1.0% garlic and medicinal plants extracts (GP-II) for 4 weeks. Blood glucose in GP group was significantly decreased, but not significantly different between GP-I and GP-II group. Albumin content of serum was significantly increased in GP groups, while total lipid, cholesterol and triglyceride of serum were significantly decreased in GP group. Total cholesterol and triglyceride were not significantly different between GP-I and GP-II group. LDL-cholesterol in blood was decreased to 58% in GP-I group and 73% in GP-II group compared to the control group, it's contents were the lowest amounts among the normal, control and experimented groups. Lipid levels in liver of rat administered with alcohol were decreased in GP group and significantly different in GP-II group. GOT and r-GTP activities were significantly higher in control than normal group, while GPT and ALP activities were not significant in groups administered with alcohol. Activities of GOT, GPT and r-GTP were significantly lower in GP group than control group, while ALP activity was not significant in all groups. TBARS contents were not significant in serum, but it's contents in liver were significantly decreased in GP groups than control group. DPPH radical scavenging ability in serum and liver was significantly increased in GP groups. These results indicate that garlic and medicinal plants extracts were effective in improving and protecting liver disorder induced from long-term alcohol consumption.

• The Korean Society of Law and Medicine
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• v.19 no.2
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• pp.139-171
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• 2018

The 「Act on Remedies for Injuries from Medical Malpractice and Mediation of Medical Disputes」(hereinafter referred to as 'the Act on Mediation of Medical Disputes') provides that the state should compensate the victims of medical accidents occurred irresistibly in childbirth despite that health and medical service personnel fulfilled their duty of care for their damage within the range of its budget(Article 46 of the Act on Mediation of Medical Disputes). Given that victims of medical accidents could expect demage recovery only through lawsuits thus far, this act can be said to be a groundbreaking act. However, However, as 30% of the costs for such medical accident compensation projects are borne by those who have records of childbirth among the founders of health and medical institutions (Article 21 of the Act on Mediation of Medical Disputes), there has been a question about whether doctors are held responsible despite that the accidents such as the deaths of mothers and newborn babies occurred irresistibly without doctors' fault. However, recently, the Constitutional Court ruled that 'the range of founders of health and medical institutions' and 'share ratios of finances for compensation' in Article 46 (3) of the Act on Mediation of Medical Disputes' related to the imposition of the share of costs are institutional (Constitutional Court ruling dated April 26, 2018, 2015Heonga13, hereinafter referred to as 'the ruling in the case'). Although the ruling in the case was made based on only the principle of statutory reservation and the principle of ban on comprehensive authorization, this paper added a practical judgment. This paper proved that the share of costs in this case has the nature of burden charges in pursuit of study and does not infringe on the property rights of the founders of health medical institutions even in light of the principle of proportionality because there is a legitimate reason for imposing the burden charge. The imposition of the share of costs in the system for compensation for medical accidents occurred irresistibly is against the principle of liability with fault in part. However, the medical accident compensation projects are rational a national policy for the victims of medical accidents and the medical world clearly gains some benefits from the effect to terminate medical disputes. The expansion of finances for compensation through the payments of the share of costs will reduce the suffering and misunderstanding of victims of medical accidents occurred in the process of childbirth and will be very helpful to the construction of stable treatment environments of medical workers by quickly establishing the medical accident compensation projects as such.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.5 no.1
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• pp.1-10
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• 2002

Purpose; Dysregulation of gastric epithelial cell proliferation and apoptosis are important in development of ulcer, atrophy and neoplasia in Helicobacter pylori (H. pylori) infection. The aim of this study was to investigate the effect of infection of H. pylori on gastric epithelial cell proliferation and apoptosis in children. Methods: Histological grading by updated Sydney system, PCNA immunostaining and TUNEL method were performed in H. pylori positive (N=58) and negative (N=40) gastric biopsy specimens. Results: In H. pylori positive children, there were significantly higher grade of polymorphonuclear neutrophil activity (P=0.000), chronic inflammation (P=0.000), epithelial damage (P=0.000) and lymphoid follicles (P=0.000) than in H. pylori negative children. Intestinal metaplasia was not seen in H. pylori positive children. PCNA index was significantly different between H. pylori positive children ($67.8{\pm}18.13$) and H. pylori negative children ($54.8{\pm}14.46$, P=0.000). There was positive correlation between PCNA index and H. pylori density (r=0.277, P=0.007), polymorphonuclear neutrophil activity (r=0.280, P=0.007) and chronic inflammation (r=0.284, P=0.006). Apoptosis index of H. pylori positive children ($0.44{\pm}0.447$) was significantly higher than of H. pylori negative children ($0.14{\pm}0.196$, P=0.000). There was positive correlation between apoptosis index and H. pylori density (r=0.472, P=0.000), polymorphonuclear neutrophil activity (r=0.370, P=0.001) and chronic inflammation (r=0.483, P=0.000). There was positive correlation between PCNA index and apoptosis index (r=0.353, P=0.003). Conclusion: The PCNA and apoptosis index in H. pylori positive children were significantly higher than in H. pylori negative children. This study suggested that gastric epithelial cell proliferation and apoptosis are important to pathogenesis of H. pylori infection in children.

• Korean Journal of Ecology and Environment
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• v.42 no.2
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• pp.260-269
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• 2009

Hwabuk Dam has been under construction to reduce flood damage in Nakdong River watershed and to supply stable water for middle area of Gyeongbuk Province. Therefore, fish investigation in up and downstream of the dam was conducted from 2004 to 2008 in order to determine any negative effect on fish community due to dam construction and to use as fundamental data for conserving species diversity and maintaining stream health. According to data analysis on water quality, temperature, dissolved oxygen, pH, suspended solids, and total E-coli had seasonal variation, but they did not significantly differ in sites. However, biological and chemical oxygen demand, chlorophyll-a, nitrogen, and phosphorus representing organic matter and nutrient concentration were higher in upper site and decreased to lower site so that they differed by site. Concentration of arsenic among the heavy metals was less than 0.05 mg $L^{-1}$, which is regulated for protection of human health in water quality standard, except for 0.092 mg $L^{-1}$ in June 2005. During the study period, the total number of fish caught from the 6 sites was 10,263 representing 7 families 19 species. Among them, dominant and subdominant species were Korean chub (Zacco koreanus, 62.5%) and Chinese minnow (Rhynchocypris oxycephalus, 10.6%) which inhabit mostly in mid and upper streams, Korea. Among the 19 species, Korean endemic species were 9 species (47.4%) including Korean slender gudgeon (Squalidus gracilis majimae), Korean dark sleeper (Odontobutis platycephala), and Korean shiner (Coreoleuciscus splendidus). There was several individuals of the $1^{st}$-class endangered species, Naktong nose loach (Koreocobitis nahtongensis), caught in 2005${\sim}$2007, and no introduced species of fish was found in entire sampling period. According to result of community analysis, dominance index decreased toward lower site, but diversity and richness indices increased toward lower site. The equation of length-weight relationship on the dominant species was TW=0.000003$(TL)^{3.2603}$. The parameter b in the equation was greater than 3.0 indicating good nutritional condition in the populations. Compared to populations of Korean chub in other streams, the population in Hwabuk Dam watershed had higher mean of condition factor by size indicating better growth rate. With fish fauna and multi-metric health assessment model in each sampling attempt, index of biotic integrity (IBI) was evaluated and it resulted mostly in good (26${\sim}$35) and excellent (36${\sim}$40) condition in all sites, and the mean of IBI was the highest in site 5. The results indicate that it is very important to study not only environmental impact assessment with fish composition but also stream health assessment in order to conserve healthy aquatic ecosystem.

• Journal of Food Hygiene and Safety
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• v.32 no.6
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• pp.536-541
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• 2017

The object of this study was to investigate the inhibitory effects of Litsea japonica fruit flesh extract (LJF-HE) on gastritis of an stress-induced SD rat model. Rats were randomly divided into six groups: Normal (normal group), Control (stress-induced gastritis), Ranitidine (stress-induced gastritis and ranitidine 50 mg/kg), LJF-HE-L (stress-induced gastritis pretreated with L. japonica fruit flesh extract at 30 mg/kg), LJF-HE-M (stress-induced gastritis pretreated with L. japonica fruit flesh extract at 60 mg/kg), LJF-HE-H (stress-induced gastritis pretreated with L. japonica fruit flesh extract at 120 mg/kg). In groups treated with LJF-HE, gastric mucosal damage and pepsin activity were reduced. Additionally, there were decreases in the expression of cholecystokinin 2 receptor (CCK-2r) in the gastric lesions. The plasma levels of IL-$1{\beta}$ slightly but significantly decreased in LJF-HE treated groups compared to control. The plasma level of PGE2 was also significantly increased in LJF-HE treated groups. These results suggest that LJF-HE has the ability to reduce of the severity stress-induced gastritis.