• Journal of Korea Water Resources Association
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• v.54 no.3
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• pp.181-190
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• 2021

In this study, a large-scale levee breach experiment from lateral overflow was conducted to verify the effect of the new reinforcement method applied to the levee's surface. The new method could prevent levee failure and minimize damage caused by overflow in rivers. The levee was designed at the height of 2.5 m, a length of 12 m, and a slope of 1:2. A new material mixed with biopolymer powder, water, weathered granite, and loess in an appropriate ratio was sprayed on the levee body's surface at a thickness of about 5 cm, and vegetation recruitment was also monitored. At the Andong River Experiment Center, a flow (4 ㎥/s) was introduced from the upstream of the A3 channel to induce the lateral overflow. The change of lateral overflow was measured using an acoustic doppler current profiler in the upstream and downstream. Additionally, cameras and drones were used to analyze the process of the levee breach. Also, a new method using 3D point cloud for calculating the surface loss rate of the levee over time was suggested to evaluate the performance of the levee reinforcement method. It was compared to existing method based on image analysis and the result was reasonable. The proposed 3D point cloud methodology could be a solution for evaluating the performance of levee reinforcement methods.

• Journal of Ginseng Research
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• v.45 no.2
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• pp.295-304
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• 2021

Background: Acute promyelocytic leukemia (APL) is a hematopoietic malignancy driven by promyelocytic leukemia-retinoic acid receptor A (PML-RARA) fusion gene. The therapeutic drugs currently used to treat APL have adverse effects. 20(S)-ginsenoside Rh2 (GRh2) is an anticancer medicine with high effectiveness and low toxicity. However, the underlying anticancer mechanisms of GRh2-induced PML-RARA degradation and apoptosis in human APL cell line (NB4 cells) remain unclear. Methods: Apoptosis-related indicators and PML-RARA expression were determined to investigate the effect of GRh2 on NB4 cells. Z-VAD-FMK, LY294002, and C 87, as inhibitors of caspase, and the phosphatidylinositol 3-kinase (PI3K) and tumor necrosis factor-α (TNF-α) pathways were used to clarify the relationship between GRh2-induced apoptosis and PML-RARA degradation. Results: GRh2 dose- and time-dependently decreased NB4 cell viability. GRh2-induced apoptosis, cell cycle arrest, and caspase3, caspase8, and caspase9 activation in NB4 cells after a 12-hour treatment. GRh2-induced apoptosis in NB4 cells was accompanied by massive production of reactive oxygen species, mitochondrial damage and upregulated Bax/Bcl-2 expression. GRh2 also induced PML/PML-RARA degradation, PML nuclear bodies formation, and activation of the downstream p53 pathway in NB4 cells. Z-VAD-FMK inhibited caspase activation and significantly reversed GRh2-induced apoptosis and PML-RARA degradation. GRh2 also upregulated TNF-α expression and inhibited Akt phosphorylation. LY294002, an inhibitor of the PI3K pathway, enhanced the antitumor effects of GRh2, and C 87, an inhibitor of the TNF-α pathway, reversed NB4 cell viability, and GRh2-mediated apoptosis in a caspase-8-dependent manner. Conclusion: GRh2 induced caspase-dependent PML-RARA degradation and apoptosis in NB4 cells via the Akt/Bax/caspase9 and TNF-α/caspase8 pathways.

• Korean Journal of Remote Sensing
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• v.37 no.3
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• pp.577-589
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• 2021

Drone mapping systems can be applied to many fields such as disaster damage investigation, environmental monitoring, and construction process monitoring. To integrate individual sensors attached to a drone, it was essential to undergo complicated procedures including time synchronization. Recently, a variety of composite sensors are released which consist of visual sensors and GPS/INS. Composite sensors integrate multi-sensory data internally, and they provide geotagged image files to users. Therefore, to use composite sensors in drone mapping systems, mapping accuracies from composite sensors should be examined. In this study, we analyzed the mapping accuracies of a composite sensor, focusing on the data acquisition area and pre-calibration effect. In the first experiment, we analyzed how mapping accuracy varies with the number of ground control points. When 2 GCPs were used for mapping, the total RMSE has been reduced by 40 cm from more than 1 m to about 60 cm. In the second experiment, we assessed mapping accuracies based on whether pre-calibration is conducted or not. Using a few ground control points showed the pre-calibration does not affect mapping accuracies. The formation of weak geometry of the image sequences has resulted that pre-calibration can be essential to decrease possible mapping errors. In the absence of ground control points, pre-calibration also can improve mapping errors. Based on this study, we expect future drone mapping systems using composite sensors will contribute to streamlining a survey and calibration process depending on the data acquisition circumstances.

• Journal of the wind engineering institute of Korea
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• v.22 no.4
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• pp.155-161
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• 2018

In modern society, damage caused by strong winds such as typhoons is expected to increase due to urbanization and global warming. In order to test the reinforcement performance of the newly developed window protection device, two-point force test and uniformly distributed load test were carried out on non-reinforced plate glass. It reinforcement performance of the window protection device was evaluated based on the flexural performance improvement. The analytical performance of the window protection device was evaluated by analysis using differential equations of elastic loading method and deflection curve and Midas-Gen. First, the analytical window protection device was evaluated by formulae derived using differential equations of elastic loading and deflection curve. The validity of the derived formulae investigated by comparing the maximum deflection of the central part of the plate with the experimental value and the theoretical value at maximum load. Then the results were compared with those by finite element FE method using Midas-Gen. Under the experimental conditions, with the window protection device, stress reduction effect up to 40% and deflection reduction up to 71.4% under the same load were obtained. It was also found that it is advantageous to perform the FE analysis using the plate element when the performance is evaluated because the error of FE analysis result using plate elements is far less than that using beam elements.

• Journal of Wetlands Research
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• v.23 no.2
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• pp.154-162
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• 2021

The naturally opened Han river estuary is a place where the flows of the Han river, Imjin river, Yaesung river meet with West Sea of Korea, so the hydrodynamic mechanism(Impact-Response) structure of Han river estuary is complex. Continuous observation and measurement due to the morphological characteristics at the estuary are required to maintain the estuary environment and river management facilities. However, the Sannam wetland(the study area) is in the military operation area. Therefore, Sannam wetland has the limited access under the control from military office. In 2020, there had a natural disaster due to flooding in August and COVID-19, and it made a survey hard. The noncontact survey technique, the analysis of LANDSAT images at Sannam wetland, was applied to analyze riverbed fluctuation and morphological transformation around Sannam wetland. LANDSAT images obtained from EarthExplorer, USGS and analyzed by QGIS. The analysis was performed based on the area and the distance near Sannam wetland. As a result, an erosion was happened on the downstream of the study area, and the upstream of the study area did not have any serious sediment transport. Considering the resolution of LANDSAT images, this noncontect survey technique is applicable to manage the study area. From the analysis of LANDSAT images, it is assumed that the tidal effect is greater than the inflow from the upstream. The pattern change of tidal response causes the damage of the river facilities near the Hangang river estuary.

• Korean journal of applied entomology
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• v.59 no.4
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• pp.421-425
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• 2020

We investigated an ecologically-sensitive method to control Polyphagotarsonemus latus in a green perilla polyvinyl house using concentrated pyrethrum. The survival rates of Polyphagotarsonemus latus nymphs and adults to 2%, 4%, and 6% pyrethrum 3 days after spraying were 58.1%, 27.5%, and 22.7% respectively, and 73.4%, 37.3%, and 30.6% at 5 days after spraying. These results show that the most effective control occurred using 6% pyrethrum. To investigating the densities of P. latus on a 1 cm diameter leaf-disk of green perilla, we sprayed the leaf every 10 days from May 10 with 6% pyrethrum 1,000 times and milbemectin EC 2% 1,000 times. The period chosen was one where the incidence of P. latus could be predicted. The density was kept low during the treatment period. However, if leaf damage had already occurred from P. latus, the density could not be decreased by spraying 1 or 2 times each week where milbemectin EC 2% was used, but the population could be reduced when sprayed 3 times. Therefore, in order to effectively control P. latus in green perilla greenhouses, it is important to begin treatment at an early stage when P. latus are first observed.

• Journal of the Korean Geotechnical Society
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• v.37 no.1
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• pp.29-41
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• 2021

Although underground works are essential to use underground spaces in urban areas efficiently, various damages caused by constructions have often occurred, making them major social problems. Since 2018, it is stipulated in the Special Act on Underground Safety Management that appropriate construction methods must be used in the design stage to prevent various damage cases. This Special Act includes establishing an area subject to underground safety impact assessment, analysis of ground and geological status, review of effects caused by changes in groundwater, review of ground safety, and establishment of measures to secure underground safety. This study area consists of various strata in order of landfill, sedimentary silt, sedimentary sand, sedimentary gravel, weathering zone, and foundation rock. Also, the slurry wall, a highly rigid underground continuous wall, was chosen as a construction method to consider high water table distribution and minimize the influence of the surroundings in this area. However, ground subsidence occurred on the road nearby in December 2019 due to the inflow of loosening soil to the construction area. Thus, several types of site investigations were conducted to suggest an appropriate analysis method and to find out loosed ground behavior and its area for the subsided site. As a result, new design soil properties were re-calculated, and the reinforcement measures were proposed through analytical verification.

• Journal of Wetlands Research
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• v.23 no.1
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• pp.1-6
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• 2021

The average annual rainfall in Busan to increase, and in case of Oncheon-Chen in Busan, frequent flooding occurred frequently. The middle and lower reaches of the Oncheon-Chen are relatively flat and urban areas are developed. Therefore, due to the frequent flooding of rivers and the large flood damage, a method of effectively eliminating the flow rate of Oncheon-Chen in the event of heavy rain is needed. In this study, underground waterway was established in the east of Hoedong-Reservoir as a measure to reduce floods in hot springs and simulated with EPA-SWMM. The information needed to construct the basin was utilized by GIS. In middle part of the Suyeong-Gang, there is a Hoedong-Reservoir and a dam is installed and has better conditions than the Nakdong-Gang. It also analyzed the effect of the Oncheon-Chen flow through the underground waterway on the Suyeong-Gang when it was transferred to the Hoedong-Reservoir. It was analyzed that the flood reduction rate at the flood risk points set up in this study was reduced by 24.64% on average when the underground waterway was installed, and the inflow of the water into the Suyeong-Gang increased by 1% on average when the flow rate was excluded by the Suyeong-Gang.

• Herbal Formula Science
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• v.29 no.2
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• pp.81-91
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• 2021

Objectives : This study was conducted to evaluate the efficacy of a complex mixture of natural substances of ginseng and baeknyeoncho on the arthritic rats. Methods : In vitro experiments were conducted to ensure the stability of the complex. After setting toxicity and concentration by MTT assay, the antioxidant effect was measured through DPPH and ABTS radical scavenging activity. To confirm the anti-inflammatory effects of the complex, levels of nitric oxide (NO) and pro-inflammatory cytokines (IL-1β, TNF-α) were measured in LPS-treated macrophage cell lines (RAW264.7). We injected monosodium iodoacetate (MIA) 50 μl (60 mg/ml) into knee joints of rats to induce osteoarthritis. The rats were divided into three groups (normal (n=5), control (n=5), and OR (n=5) group). The control group consumed 2 mg/kg of physiological saline once a day for 4 weeks, and the OR group was mixed at a concentration of 416.5 mg/kg of Baengnyeoncho (O) and 208.25 mg/kg of red ginseng (R) and ingested 1 mL each 5 days a week. Results : This complex increased the DPPH and ABTS radical scavenging rate. The complex decreased NO production and pro-inflammatory cytokine production of macrophages. In the OR group, the secretion of cytokine in serum was decreased. In histopathological examination, the joint tissue of the composite showed less damage to the synovial membrane, cartilage, and fibrous tissue than the control group. Conclusions : As a result of this study, natural complexes have antioxidant, anti-inflammatory and cartilage protection effects. Therefore, we expect the complex to be effective in treating osteoarthritis.

• Korean Journal of Agricultural and Forest Meteorology
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• v.23 no.4
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• pp.222-234
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• 2021

Airborne-pests can be introduced into Korea from overseas areas by wind, which can cause considerable damage to major crops. Meteorological models have been used to estimate the wind trajectories of airborne insects. The objective of this study is to analyze the effect of input settings on the prediction of areas where airborne pests arrive by wind. The wind trajectories were predicted using the HYbrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model. The HYSPLIT model was used to track the wind dispersal path of particles under the assumption that brown plant hopper (Nilaparvata lugens) was introduced into Korea from sites where the pest was reported in China. Meteorological input data including instantaneous and average wind speed were generated using meso-scale numerical weather model outputs for the domain where China, Korea, and Japan were included. In addition, the calculation time intervals were set to 1, 30, and 60 minutes for the wind trajectory calculation during early June in 2019 and 2020. It was found that the use of instantaneous and average wind speed data resulted in a considerably large difference between the arrival areas of airborne pests. In contrast, the spatial distribution of arrival areas had a relatively high degree of similarity when the time intervals were set to be 1 minute. Furthermore, these dispersal patterns predicted using the instantaneous wind speed were similar to the regions where the given pest was observed in Korea. These results suggest that the impact assessment of input settings on wind trajectory prediction would be needed to improve the reliability of an approach to predict regions where airborne-pest could be introduced.