• 제목/요약/키워드: Damage Effect

검색결과 5,921건 처리시간 0.034초

Protective Effect of Crataegus pinnatifida and Cinnamomum cassia on Ethanol-induced Cytotoxicity and DNA Damage in HepG2 Cells

  • Kim, Nam Yee;Song, Eun Jeong;Heo, Moon Young
    • Natural Product Sciences
    • /
    • 제20권4호
    • /
    • pp.237-242
    • /
    • 2014
  • Plant extracts produced from branches of Crataegus pinnatifida and barks of Crataegus pinnatifida inhibited ethanol-induced cytotoxicity and DNA damage in liver cells. Furthermore, these two extracts inhibited the expression and activities of CYP2E1 enzyme. Cinnamomum cassia had a better effect on inhibition of DNA damage than Crataegus pinnatifida, as well as showed a high tendency to inhibit CYP2E1 expression and catalytic activities. It is considered that extracts produced from Crataegus pinnatifida or Cinnamomum cassia have an effect to reduce ethanol-induced cytotoxicity and DNA damage in liver cells. Therefore, we suggest to use Crataegus pinnatifida and Cinnamomum cassia and their ingredients as potential candidate substances to prevent and treat ethanol-induced cytotoxicity and genotoxicity in liver cells.

충격손상을 가진 CFRP 적층복합재료의 피로수명예측모델 (A Model for Fatigue Life In CFRP Laminates with Impact Damage)

  • 강기원;김정규
    • 대한기계학회논문집A
    • /
    • 제24권11호
    • /
    • pp.2828-2835
    • /
    • 2000
  • This paper presents the fatigue behavior of composite materials with impact-induced damage. The impact damage parameter is proposed to evaluate the effect of impact damage on fatigue life. Subsequently, a new model is developed to predict the fatigue life of impacted composite materials. Also, a stochastic model is proposed to describe the variation of fatigue life due to the material nonhomogeneity. For these models, the fatigue tests were performed on the unimpacted and impacted composite materials, The effect of impact damage on fatigue life can be characterized by the impact damage parameter. Additionally, the results by the present fatigue life prediction model agree will with experimental results regardless of applied impact energy. Also, the variation of fatigue life can be described by the present stochastic model and is reduced with applied impact energy.

충격손상 CFRP 적층복합재료의 피로특성 (Fatigue Characteristics in CFRP Laminates with Impact Damage)

  • 강기원;김정규
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2000년도 추계학술대회논문집A
    • /
    • pp.225-230
    • /
    • 2000
  • This paper presents the fatigue behavior of composite materials with impact-induced damage. The impact damage parameter is proposed to evaluate the effect of impact damage on fatigue life. Subsequently, a new model is developed to predict the fatigue life of impacted composite materials. Also, a stochastic model is proposed to describe the variation of fatigue life due to the material nonhomogeneity. For these models, the fatigue tests were performed on the unimpacted and impacted composite materials. The effect of impact damage on fatigue life can be characterized by the impact damage parameter. Additionally, the results by the present fatigue life prediction model agree well with experimental results regardless of applied impact energy. Also, the variation of fatigue life can be described by the present stochastic model and is reduced with applied impact energy.

  • PDF

Investigation on damage development of AP1000 nuclear power plant in strong ground motions with numerical simulation

  • Chen, Wanruo;Zhang, Yongshan;Wang, Dayang;Wu, Chengqing
    • Nuclear Engineering and Technology
    • /
    • 제51권6호
    • /
    • pp.1669-1680
    • /
    • 2019
  • Seismic safety is considered to be one of the key design objectives of AP1000 nuclear power plant (NPP) in strong earthquakes. Dynamic behavior, damage development and aggravation effect are studied in this study for the three main components of AP1000 NPP, namely reinforced concrete shield building (RCSB), steel vessel containment (SVC) and reinforced concrete auxiliary building (RCAB). Characteristics including nonlinear concrete tension and compressive constitutions with plastic damage are employed to establish the numerical model, which is further validated by existing studies. The author investigates three earthquakes and eight input levels with the maximum magnitude of 2.4 g and the results show that the concrete material of both RCSB and RCAB have suffered serious damage in intense earthquakes. Considering RCAB in the whole NPP, significant damage aggravation effect can be detected, which is mainly concentrated at the upper intersection between RCSB and RCAB. SVC and reinforcing bar demonstrate excellent seismic performance with no obvious damage.

전기저항 측정과 음향방출을 이용한 표면 처리된 탄소 나노튜브와 나노 섬유 강화 에폭시 복합재료의 비파괴적 손상 감지능 (Nondestructive Damage Sensitivity for Functionalized Carbon Nanotube and Nanofiber/Epoxy Composites Using Electrical Resistance Measurement and Acoustic Emission)

  • Kim, Dae-Sik;Park, Joung-Man;Kim, Tae-Wook
    • 한국복합재료학회:학술대회논문집
    • /
    • 한국복합재료학회 2003년도 추계학술발표대회 논문집
    • /
    • pp.42-45
    • /
    • 2003
  • Nondestructive damage sensing and mechanical properties for acid-treated carbon nanotube (CNT) and nanofiber (CNF)/epoxy composites were investigated using electro-micromechanical technique and acoustic emission (AE). Carbon black (CB) was used to compare to CNT and CNF. The results were compared to the untreated case. The fracture of carbon fiber was detected by nondestructive acoustic emission (AE) relating to electrical resistivity under double-matrix composites test. Sensing for fiber tension was performed by electro-pullout test under uniform cyclic strain. The sensitivity for fiber damage such as fiber fracture and fiber tension was the highest for CNT/epoxy composites. Reinforcing effect of CNT obtained from apparent modulus measurement was the highest in the same content. For surface treatment case, the damage sensitivity and reinforcing effect were higher than those of the untreated case. The results obtained from sensing fiber damage were correlated with the morphological observation of nano-scale structure using FE-SEM. The information on fiber damage and matrix deformation and reinforcing effect of carbon nanocomposites could be obtained from electrical resistivity measurement as a new concept of nondestructive evaluation.

  • PDF

섬유소계 직물의 탄화날염가공이 섬유손성에 미치는 영향 (Effect of Burn out Print Finishing on Cellulose Fiber Damage)

  • 신정숙;송석규
    • 한국의류학회지
    • /
    • 제25권1호
    • /
    • pp.124-131
    • /
    • 2001
  • To find out the effect of burn out print finishing for better quality of fabric, examined processing which could make less damages on the fiber because the biggest problem is remained fibers damage after burn out print finishing. Fiber damage examined to the condition of finishing material NaHSO$_4$and H$_2$SO$_4$, 3~10min., 100~13$0^{\circ}C$, glycerin. The fiber damages evaluated the break strength and the surface condition by SEM. Among satin, pile fabric which remained fiber is silk, warp knitted fabric which remained fiber is polyester, the fibers damage level were warp knitted fabric$0^{\circ}C$, glycerin and for 6 minutes by NaHSO$_4$. When carbonized by 20%. 50% and 70% to express textile design, carbonizing rate was not effect on the fiber damage very much. There was almost no damages with glycerine, and almost no damages during 3~6minutes fixation time, 10$0^{\circ}C$ steaming heat fixation by NaHSO$_4$and H$_2$SO$_4$. Without glycerine, there were damage by hydrolysis on polyesters surface and the fiver was broken by fixation time.

  • PDF

Site classes effect on seismic vulnerability evaluation of RC precast industrial buildings

  • Yesilyurt, Ali;Zulfikar, Abdullah C.;Tuzun, Cuneyt
    • Earthquakes and Structures
    • /
    • 제21권6호
    • /
    • pp.627-639
    • /
    • 2021
  • Fragility curves are being more significant as a useful tool for evaluating the relationship between the earthquake intensity measure and the effects of the engineering demand parameter on the buildings. In this paper, the effect of different site conditions on the vulnerability of the structures was examined through the fragility curves taking into account different strength capacities of the precast columns. Thus, typical existing single-story precast RC industrial buildings which were built in Turkey after the year 2000 were examined. The fragility curves for the three typical existing industrial structures were derived from an analytical approach by performing non-linear dynamic analyses considering three different soil conditions. The Park and Ang damage index was used in order to determine the damage level of the members. The spectral acceleration (Sa) was used as the ground motion parameter in the fragility curves. The results indicate that the fragility curves were derived for the structures vary depending on the site conditions. The damage probability of exceedance values increased from stiff site to soft site for any Sa value. This difference increases in long period in examined buildings. In addition, earthquake demand values were calculated by considering the buildings and site conditions, and the effect of the site class on the building damage was evaluated by considering the Mean Damage Ratio parameter (MDR). Achieving fragility curves and MDR curves as a function of spectral acceleration enables a quick and practical risk assessment in existing buildings.

손상된 재료의 탄소성변형에 대한 운동학적 해석 (Kinematic Description of Damage-Elastoplastic Deformation)

  • 박대효;박용걸
    • 전산구조공학
    • /
    • 제10권4호
    • /
    • pp.131-142
    • /
    • 1997
  • 본 논문에서는 4차 손상유효 tensor를 이용하여 유한 탄소성변형에 대한 운동학적인 손상해석이 소개된다. 이는 뼈대구조에서의 연속체 손상역학의 유효응력개념을 통하여 이루어진다. 소규모 변형율상태에만 적용할 수 있는 등가변형율 혹은 에너지법과는 달리 제안된 운동학적인 방법은 유효변형율과 유한변형율에 적용할 수 있는 소규모 변형상태에 있어서의 손상탄소성변형율 사이의 관계를 제공한다. 이는 실제 형상과 가상의 유효형상 모두에 대한 변형장의 운동학을 직접 고려하여 수행된다. 이 방법은 등가변형율이나 변형율 에너지 경우처럼 소규모 변형율에 한정되지 않으며, 유한변형율에 대한 에너지등가의 가정과 일치함을 보여준다. 본 논문에서는 손상이 탄소성영역에서 운동학적으로 표현되며, 손상유효 tensor는 2차 손상 tensor를 통해 손상을 운동학적 측정값이 항으로 특징지워진다.

  • PDF

LPG 충전소 중대사고의 피해효과에 관한 연구 - 부천 LPG충전소 사고 사례를 중심으로 - (A Study on Damage Effect from Major Accident of LPG Charging Facility - A case study of an LPG Charging and Automotive Outlet -)

  • 노삼규;김태환;함은구;홍창문
    • 시큐리티연구
    • /
    • 제2호
    • /
    • pp.83-98
    • /
    • 1999
  • The LPG station's explosion at Bucheon city was a major accident which with rare frequency of occurrence but large damage effect. Therefore, to prevent similar accident in the future from LPG chargings stations which located at inner urban area, it needs to identify the damage effects of such facilities by comparing theoretically quantities risks-PHAST. The BLEVE effects from the accident showed similar level in case of heat flux, however, the over pressure level reflected at reduced distance. The structure damage to the nearby area showed comparatively large reduction of concrete strength and shape changes through by heat effect while the overpressure effect was small.

  • PDF

지오그리드의 시공 시 손상 및 크리프 변형의 복합효과 평가 (Assessment of Combined Effect of Installation Damage and Creep Deformation of Geogrids)

  • 조삼덕;이광우;오세용;이도희
    • 한국지반공학회논문집
    • /
    • 제21권5호
    • /
    • pp.153-161
    • /
    • 2005
  • 시공 시 손상 및 크리프 변형의 복합효과가 지오그리드의 장기설계인장강도에 미치는 영향을 평가하기 위하여, 세 종류의 지오그리드를 대상으로 일련의 현장 내시공성시험 및 크리프시험을 수행하였다. 연구결과, 지오그리드의 시공시 손상 및 크리프 변형 특성은 지오그리드의 재질 및 제조방법에 크게 영향을 받으며, 시공 중 지오그리드의 인장강도감소가 클수록, 시공 시 손상과 크리프 변형의 복합효과가 미치는 영향이 더 큰 것으로 나타났다. 또한 지오그리드의 인장강도 감소계수를 영향인자별로 각각 산정하여 장기설계인장강도를 평가하도록 되어 있는 현행 설계법은, 지오그리드의 시공 시 손상과 크리프 변형의 복합효과를 고려하여 강도감소계수를 산정하는 방법에 비해 지오그리드의 강도감소계수를 안전측으로 산정하는 것으로 평가되었다.