• Journal of Life Science
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• v.26 no.4
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• pp.387-397
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• 2016

The purpose of this study was to determine if heat shock proteins are involved in autophagy in skeletal muscle. We used the autophagy flux strategy, which is an LC3 II/p62 turnover assay conducted with and without an autophagy inhibitor, to determine whether 17-DMAG (an Hsp90 inhibitor/Hsp72 activator) stimulates autophagy in skeletal muscle. We treated C2C12 cells with 17-DMAG (500 nM) for 24 hr with and without the autophagy inhibitor (Bafilomycin A1, 200 ng/ml), and we injected C57BL/6 mice i.p. with 17-DMAG (10 mg/kg) daily for 7 days with and without colchicine as an autophagy inhibitor (0.4 mg/kg/day, administered on the last 2 days). C2C12 myotubes and tibialis anterior muscles were harvested for analysis of mTOR-dependent autophagy signaling pathway proteins and autophagic marker proteins (p62 and LC3 II) by Western blot analysis. The blots showed that 17-DMAG upregulated hsp72 and decreased Akt protein levels and S6 phosphorylation in C2C12 cells. However, an in vitro autophagic flux assay demonstrated that 17-DMAG did not increase LC3 II and p62 protein concentrations to a greater extent than Bafilomycin A1 treatment alone. Similarly, 17-DMAG increased Hsp72 protein levels and decreased the expression of Akt and the phosphorylation of S6 in mouse skeletal muscle. However, unlike the response seen in C2C12 myotubes, the p62 protein levels were significantly decreased in 17-DMAG-treated mouse skeletal muscle (~50%; p<0.05). The LC3 II protein levels in 17-DMAG-treated mice were increased ~2-fold more when degradation was inhibited by colchicine (p<0.01). This suggests that 17-DMAG stimulates basal autophagy in skeletal muscle but is not found in C2C12 myotubes.

• Journal of the Korea Convergence Society
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• v.7 no.6
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• pp.317-325
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• 2016

The purpose of this study was to examine the effect of the education intervention program as a nutrition program and exercise for the improvement of metabolic syndrome in women who voluntarily participated in health program in public health centers over 30 years of age. The subjects of this study were 120 women who completed the 12 - week obesity clinic program among the 400 obesity clinic participants in the northeastern of Seoul. Exercise and nutrition programs were administered on a daily basis for 1 hour every week for 12 hours with exercise and nutrition for 1 week to assess the effect of the participants on the risk factors of metabolic syndrome in health program. The metabolic syndrome and the risk of the disease were examined by analyzing the metabolic syndrome risk factors, change magnitude and change rates before and after the intervention. Waist circumference(p <.001), systolic blood pressure (p <.001), diastolic blood pressure (p <.001) and body mass index (p <.001) decreased during the 12 - week health program. Body weight (p <.01), waist circumference (p <.05), BMI (p <.01) and fat mass (p <.05) decreased more in the age group below 50 years.

• Biomolecules & Therapeutics
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• v.11 no.2
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• pp.99-108
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• 2003

Background: There is abundance of studies on the decrease in body fat through limited calorie intake or exercise; however, studies focusing simultaneously on functional foods and exercise are rare. This study was aimed to identify the effects of combination of a functional beverage and exercise on body composition and biochemical metabolic profiles. Method: Eighty-one healthy volunteers (69 females aged 19 to 50 years and 12 males aged 19 to 55 years), who maintained their body weight stable with 23 or higher in BMI (kg/$m^2$) and 25% or higher body fat for the last three months, were recruited in the study through written advertisement. All the subjects gave their informed consent, and the study was conducted in accordance with the Declaration of Helsinki. The study design was a randomized double-blind placebo-controlled parallel group design. All participants were given 12-week programed-exercise, which was performed 3 times a week. One bottle (100 ml) of test (Garcinia cambogia 300 mg, L-carnitine 20 mg, Soy peptide 1,000 mg) or placebo solution was given daily 30 min before each session of programed-exercise. BMI (body mass index), %fat, local fat amount (visceral and mid-thigh), waist circumference, skin fold thickness and some biochemical metabolic parameters like glucose, insulin and free fatty acids, etc in the blood were measured and compared before and after 12-week intervention within groups as well as between groups according to the protocol Results: Twenty six volunteers were dropped out and fifty five volunteers completed the study. At the end of 4, 8, and 12 weeks, approximately 1.98%, 3.00% and 3.50% losses of initial body weight were observed, respectively, in the test group (P<0.01), and 0.29, % ,0.74%, 1.60%, respectively, in the placebo group (P>0.05). BMI changed by 2.40%, 3.41% and 4.46%, respectively, in the test group, and 0.38%, 0.95% and 1.75%, respectively, in the placebo group, at each period of time. The reductions of body weight and BMI were significantly higher in the test group than in the placebo group at each period of time (P<0.05). Conclusions: It is thought that the combination of functional beverage, which contains mostly garcinia cambogia, L-carnitine, and soy peptide, and exercise have synergy effects on reducing body fat.

• The Korean Journal of Community Living Science
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• v.17 no.3
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• pp.15-28
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• 2006

This study is on the kindergarten uniforms in Changwon, south Gyeongsang province. The first part of this research is on whether or not students should wear uniforms and how often they should wear uniforms. The research also deals with what types of uniforms are required, how much they should cost and their size. Fifty one preschools including kindergarten and nursery were targeted for this research. The second part of the research is on the discrepancy of the labeled size and the actual size of the child. The results of the first part are as follows: A total of 46 out of 51 places adopted uniforms for their children. Sports wear style is the most popular for spring, fall and summer uniforms. For wearing frequency of kindergarten uniforms, 26 (61%) places allowed the students to wear uniforms for special events such as picnics or observation trips 17(34%) places had the students wear their uniforms on a daily basis and 2 3 times only wearing a week.'rho preschool children interviewed for this study were from 2 to 5 in lull age. However, sizes with high frequency rates were 9 to 11 and the supplied sizes of uniforms were from 5 to 17. The results of the second part are as follows: The bust girth and the shoulder width of upper garments of uniforms are bigger than children's physical size, while clothes length and sleeve length are relatively shorter. Also the bust girth of upper garments of uniforms differs in the size depending on each preschool. The waist girth and the total length of lower garments of uniforms are made smaller than children's physical sizes, while hip girth is relatively larger. In the case of lower garments, the rest parts of cloth length are smaller than upper garments of uniforms. Also, the waist girth and hip width of uniforms are smaller than those of lower garments In summer garments, while thigh width is similar in both cases. The waist width is made too small. Described in the above excluding the waist width, the rest parts are relatively larger than children's physical sizes, but shorter in the length. Due to the length, children at age 7 may wear uniforms in the level of 17. Since summer uniforms touch the students' bare skin, the rest parts excluding clothes length are shorter than these of the spring and fall uniforms. In the case of clothes length, it seems to be due to different designs. The waist width of lower garments in all the uniforms tested in this study is too small for children, requiring them to be made in a larger size.

• Clinics in Shoulder and Elbow
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• v.10 no.1
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• pp.33-41
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• 2007

Purpose: The purpose of this study was to prove the effectiveness of the open medial (glenoid-based) anterior-inferior capsular shift in patients with multidirectional shoulder instability. Materials and Methods: We reviewed 19 patients treated by medial anterior-inferior capsular shift for multidirectional shoulder instability from March, 1998 to December, 2003. 15 patients of them have experienced recurrent dislocation. 8 patients(42%) showed bilateral laxity and 11 patients(58%) generalized ligamentous laxity, and 2 patients(10.5%) voluntary subluxation. An average follow-up was 24 months (range : $9{\sim}32$ months). Results: Pain improved in 18 patients of all. There was an average loss of 10 degree of external rotation, but no limitation of activity of daily living. There was no redislocation and subluxation, but two patients had some apprehension in sports activity. With Rowe score, the result was excellent or good in all patients. There were hematoma and local skin problem in 1 patient, but all had healed up. Conclusion: Medial anterior-inferior capsular shift in multidirectional shoulder instability provided satisfactory results in pain relief, patient's satisfactions and stability of glenohumeral joint. Though some of them have anterior gleniod deformities and large Hill-Sachs lesions, we could get good stabilities.

• Clinics in Shoulder and Elbow
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• v.10 no.1
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• pp.78-83
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• 2007

Purpose: This study reports the clinical results of the tenodesis of long head of the Biceps brachii tendon with bioabsorbable interference screw by minimal open procedure. Materials and Methods: Ten cases of 10 patients (7 male, 3 female) were included in this study. The average age was 45.8 years old and the average period from the symptom onset to operation was 13.7 months. Average preoperative ASES score was 38.5. The causes of injury was; sports activities in 4 patients, unknown in 4 patients, industrial accident in 1 patient and traffic accident in 1 patient. The average follow up period was 12.1 months. Tenodesis with bioabsorbable interference screw by minimal open precedure was performed in all cases. Results: The ASES score improved to 87.5 at last follow up period and 6 cases had full range of motion of the shoulder. 4 cases had mild limited range of motion of the shoulder without any problem in normal daily activity. Conclusion: It was assumed that tenodesis of long head of the biceps brachii tendon with bioabsorbable interference screw by minimal open precedure was one of the good methods with good clinical results.

• Korean journal of communication and information
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• v.37
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• pp.204-236
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• 2007

This study explores the corrections on the Korean and the U. S. daily newspapers for the characteristics and differences through the content analysis. For the research, Chosun Ilbo, Hankyoreh Shinmun, The New York Times and The San Francisco Chronicles are selected. The main differences between the Korean and American newspapers are as follows: Firstly, the average number of newspaper errors in Korean dailies are as half as little of those in the U. S. dailies. Secondly, regarding the subcategory of mistakes, the largest thematical number is the societal matters(36.0%), followed by politics(18.3%) and economy(12.1%) for the Korean newspapers. By contrast, errors in culture(17.4%) is the most frequently made by the American newspaper reporters and editors, followed by lifestyle(8.6%), and sports(7.0%). Thirdly, in terms of content of mistakes, errors in names(26.2%) that occurred the most, followed by misidentifications(18.1%) and misattribution(15.8%) for the Korean dailies; the errors in numbers(33.7%), spelling and typographical errors(12.1%) and date(5.6%) for the U. S. dailies. Fourthly, one of the critical reasons that mistakes occurred because Korean reporters are lack of double checking the stories; the U. S. reporters simply by overlooking the articles. Finally, the Korean newspapers make use of only two kinds of correction formats, while the U.S. newspapers use six different correction formats for their newspaper readers.

• Journal of the Society of Disaster Information
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• v.10 no.4
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• pp.536-547
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• 2014

With the changing safety services and social order systems accompanied by the economic development and changing public security environment since the Chinese economic reform, the security service industry in China is growing daily and related problems are increasing. For the Chinese security service market to be activated, the monopoly of security services by the public security agencies must be removed. In addition, the research and development, expansion, and applications of safety and crime prevention technologies regarding the safety and protection of exhibition, sales, culture, sports, commerce activities, combinations of safety technologies and crime prevention processes, the provision of relevant technical operations, and the expansion of security service areas are required. Furthermore, the administration rights, property rights, and business management rights of security companies must be separated, the security headquarters must be integrated and coordinated for optimization of various resources solely by market needs, and their rights and affiliation relations must be clear. Besides, the competitiveness of security companies in the security service market must be enhanced by unifying the business management, and optimizing and sharing their resources. The security service ordinances of China that have been implemented now must be applied realistically, methods to activate the true market economy for security services must be researched, and various ordinances related to security services must be realigned in line with the characteristics of security services. Finally, for the mutual cooperation system between public and private security services, the public security agencies must acknowledge the importance of private security services and the status of security service providers in crime prevention and social order maintenance. They must establish partnership relations with each other beyond the unilateral direction and management system for security services and drive with positive attitudes the security service industry which is still in its infancy.

• Science of Emotion and Sensibility
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• v.18 no.3
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• pp.35-48
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• 2015

It is frequently found in daily life that people who experience good luck as lottery winners try to improve their background (e.g., home, car) but it has not been empirically validated why they do that. Present research attempts to explore the prediction that people who experience good luck expand the scope of attention to background and those who undergo bad luck shrink the scope of attention to adjacent objects. Findings from Experiment 1a indicate that participants who experienced good luck (won the rock-paper-scissors game) paid more attention to background and performed worse in the "find the hidden picture" (below FHP) task while those who underwent bad luck (lost the rock-paper-scissors game) paid more attention to objects, leading to better performance in the FHP task. It is also found in Experiment 1a that, if people washed their hands after experiencing good or bad luck, the opposite result occurred. Experiment 1b confirmed that the rock-paper-scissor game manipulated good and bad luck successfully and did not influence self-control. Experiment 2 shows that people who strongly believe in good luck performed poorly in FHP task while those who do not believe in good luck performed well in FHP task. Overall, three experiments support the proposed research hypotheses. Implications of the study findings for cognitive psychology and related fields including consumer and sports psychology are discussed.

• Journal of Arbitration Studies
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• v.21 no.2
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• pp.85-112
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• 2011

These days utilization of copyright in daily life and economic activities is becoming more important than ever, and IT technology is developing day by day. Along with those fact, copyright infringement and dispute is naturally increasing. This thesis dealt with the 3 different issues of ADR on copyright. The First part, introduce ADR system that was performed by Korea Copyright Committee according to Copyright law. This paper evaluate the committee's efforts to provide resolution of copyright disputes via conciliation was effective. So it needs to be look over several countries' ADR, beside conventional judicial remedy. And Korea's copyright conciliation system which is successfully operating also introduced. Second, In many countries, including South Korea are take advantage of conciliation as the way to settle down the dispute over copyright. Furthermore, looked over if we can use arbitration as tool to settle dispute or not. Currently in Korea, patent dispute is handled by Industrial Property Dispute Conciliation Committee(The Invention Promotion Act Ch.5) and Layout-design Review and Mediation Committee(The Act on the Layout-designs of Semiconductor Integrated Circuits Art.29-34), but using performance of those two committee is still too low. In comparison, the copyright committee, a affiliation organization of the ministry of culture, sports and tourism has much more result in conciliation compare with patent dispute. Copyright disputes has arbitrability of it's subject-matter and many regulating organs are interested in it. (especially, binding of arbitral award and final resolution). Take advantage of both conciliation and arbitration could be good way to resolve copyright disputes. Third, the writer look at the proposal on the creation of Northeast Regional Center for Intellectual Property ADR. Because of the nature of copyright and rapid development of internet technology, international use of work become more frequent and accordingly infringement cases are increasing. The role of commercial arbitration regimes and institutions which has progressed significantly worldwide level, but which has only just begun in the intellectual property ADR area, leads also to a clash of often very different legal cultures and protection in a market economy. International cooperation in regional area with conflict interests becomes an important alternative. But it will depend on the building of regional institutions and mechanisms. The feasibility of this proposal and preconditions were examined. Establishment of new international organization requires a lot of time, cost and efforts. And risk of failure is much too high. Therefore factual, statistical review should be preceded. In addition, technical measures, such as on-line arbitration is necessary to review also. Furthermore in order to establish new organization, the relative law, legal environment, public sentiment and international compliance must be carefully considered with factual review about the needs and economic benefits of each country Yet on complex regulatory matters such as IP and ADR, a great deal of the potential benefits from international standards arises not from the international legal framework nor even the formal content of national legislation, but from the informed and effective use made of the possibilities within the system, including by policymakers and regulators.