• Title/Summary/Keyword: DSM-5

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Polar Transmitter with Differential DSM Phase and Digital PWM Envelope

  • Zhou, Bo;Liu, Shuli
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.14 no.3
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    • pp.313-321
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    • 2014
  • A low-power low-cost polar transmitter for EDGE is designed in $0.18{\mu}m$ CMOS. A differential delta-sigma modulator (DSM) tunes a three-terminal voltage-controlled oscillator (VCO) to perform RF phase modulation, where the VCO tuning curve is digitally pre-compensated for high linearity and the carrier frequency is calibrated by a dual-mode low-power frequency-locked loop (FLL). A digital intermediate-frequency (IF) pulse-width5 modulator (PWM) drives a complementary power-switch followed by an LC filter to achieve envelope modulation with high efficiency. The proposed transmitter with 9mW power dissipation relaxes the time alignment between the phase and envelope modulations, and achieves an error vector magnitude (EVM) of 4% and phase noise of -123dBc/Hz at 400kHz offset frequency.

Genetic and Functional Analyses of the DKxanthene Biosynthetic Gene Cluster from Myxococcus stipitatus DSM 14675

  • Hyun, Hyesook;Lee, Sunjin;Lee, Jong Suk;Cho, Kyungyun
    • Journal of Microbiology and Biotechnology
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    • v.28 no.7
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    • pp.1068-1077
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    • 2018
  • DKxanthenes are a class of yellow secondary metabolites produced by myxobacterial genera Myxococcus and Stigmatella. We identified a putative 49.5 kb DKxanthene biosynthetic gene cluster from Myxococcus stipitatus DSM 14675 by genomic sequence and mutational analyses. The cluster consisted of 15 genes (MYSTI_06004-MYSTI_06018) encoding polyketide synthases, non-ribosomal peptide synthases, and proteins with unknown functions. Disruption of the genes by plasmid insertion resulted in defects in the production of yellow pigments. High-performance liquid chromatography and liquid chromatography-tandem mass spectrometry analyses indicated that the yellow pigments produced by M. stipitatus DSM 14675 might be novel DKxanthene derivatives. M. stipitatus did not require DKxanthenes for the formation of heat-resistant viable spores, unlike Myxococcus xanthus. Furthermore, DKxanthenes showed growth inhibitory activity against the fungi Aspergillus niger, Candida albicans, and Rhizopus stolonifer.

Extracting Topographic Information from SPOT-5 HRG Stereo Images (SPOT-5 HRG 스테레오 영상으로부터 지형정보 추출)

  • Lee, Jin-Duk;Lee, Seong-Sun;Jeong, Tae-Sik
    • Journal of Korean Society for Geospatial Information Science
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    • v.14 no.4 s.38
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    • pp.61-70
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    • 2006
  • This paper presents photogrammetric processing to generate digital elevation models using SPOT-5 HRG stereo images and deals with the accuracy potential of HRG (High Resolution Geometry) supermode imagery for DEM generation. After bundle adjustment was preformed for sensor modelling, digital surface models were generated through the procedures of Epipolar image resampling and image matching. The DEM extracted from HRG imagery was compared along several test sections with the the refernce DEM which was obtained from the digital topographic maps of a scale of 1 to 5000. The ratio of the zone with DEM errors less than 5m to the whole zone was 53.8%, and about 2.5m RMSE was showed when assuming that the zones larger than 5m were affected by clouds, water bodies and buildings and excluding those zones from accuracy evaluation. In addition, the three-dimensional bird's eye view model and 3D building model were producted based on the DSM which was extracted from SPOT-5 HRG data.

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Psychometric Properties of the Korean version of the PTSD Checklist-5 in Elderly Korean Veterans of the Vietnam War (월남전 참전 노인에서 한글판 외상후 스트레스 장애 체크리스트-5의 정신측정학적 특성)

  • Kim, Jong Won;Chung, Hae Gyung;Choi, Jin Hee;So, Hyung Seok;Kang, Suk-Hoon;Kim, Dong Soo;Moon, Jung Yoon;Kim, Tae Yong
    • Anxiety and mood
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    • v.13 no.2
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    • pp.123-131
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    • 2017
  • Objective : The PTSD Checklist (PCL) is a self-report screen for posttraumatic stress disorder (PTSD) that can be scored for both diagnostic assessment and symptom severity measurement. The most recent revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) contains a number of changes to the definition of PTSD, and the aim of this study was to assess the psychometric properties of the Korean version of the PCL for the DSM-5 (PCL-5-K). Methods : The participants were 204 Korean veterans of the Vietnam War who completed the PCL-5-K, the Mini Mental Status Examination (MMSE), PTSD module of Structured Clinical Interview for DSM-5, Research Version (SCID5-RV PTSD module), Korean version of Impact of Event Scale-Revised (IES-R-K) and Combat Exposure Scale (CES-K). Results : The PCL-5-K demonstrated good internal consistency (${\alpha}=0.972$) and test-retest reliability (r=0.96); the suggested cut-off score for PTSD diagnosis was ${\geq}37$ with 0.88 sensitivity and 0.96 specificity. The PCL-5-K scale correlated highly with the IES-R-K and CES-K. Factor analysis identified only one factor. Conclusion : Among elderly Korean veterans of the Vietnam War, the PCL-5-K demonstrated similar psychometric qualities to those of both the original PCL and subsequent versions. It is expected that the PCL-5-K will be a useful PTSD screening tool.

Effect of Far-Infrared Irradiation and Heat Treatment on the Antioxidant Activity of Extracts from Defatted Soybean Meal (원적외선 조사와 열처리가 탈지대두박 추출물의 항산화능에 미치는 영향)

  • Rim, A-Ram;Jung, Eun-Sil;Kim, So-Young;Lee, Seung-Cheol
    • Applied Biological Chemistry
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    • v.48 no.4
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    • pp.400-403
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    • 2005
  • The effect of far-infrared (FIR) irradiation and heat treatment on the antioxidant activity of extracts from defatted soybean meal (DSM) was evaluated. DSM were placed in pyrex petri dishes (8.0 cm diameter) and irradiated at $150^{\circ}C$ for 5, 10, 15, 20, 40 or 60 min with a FIR heater or simple heater. After FIR irradiation or simple heat treatment at same conditions, methanol extracts of DSM were prepared and total phenol contents (TPC), radical scavenging activity (RSA) and reducing power of the extracts were determined. The antioxidant activities of the extracts increased as the time of heating or FIR-irradiation increased. When DSM were FIR-irradiated at $150^{\circ}C$ for 15 min, the values of TPC, RSA, and reducing power of the extracts increased from 31.62 mg/ml to 57.51 mg/ml, 11.6% to 53.1%, and 0.068 to 0.147, respectively, compared to the untreated controls. Simple heat treatment of DSM under the same conditions ($150^{\circ}C$ for 15 min) also increased the TPC, RSA, and reducing power of the extracts from to 58.04 mg/ml, 65.2% and 0.160, respectively. The results indicated that appropriate FIR-irradiation or heat treatment on DSM increased the antioxidant activities of methanolic extracts.

GENETIC STUDY IN AUTSTIC DISORDER - Chromosomal Analysis - (자폐장애 아동의 유전연구 - 염색체 분석 -)

  • Jung, Chul-Ho;Lee, Inn-Hwan
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.2 no.1
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    • pp.66-75
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    • 1991
  • The authors studied chromosomal abnormalities in 38 autistic children meeting the diagnostic criteria of DSM-III-R in order to investigate genere factor in autistic disorder There were 28 males and 10 females, with the mean age being $108.8{\pm}28.5months(70-156months).$ All samples were analyzed on short-term lymphocyre cultures in Medium 199 that contained FUdR. The fragile X chromosome was not found in any of the patients. There were other chromosomal abnormalities in 14(36.8%) of 38 patients, such as breakage, 11cases ; gap, 2case ; breakage and gap, 1 case. In grouping of chromosomal abnormalities, group A patients were 4 cases ; group C were 3 cases ; group A and B was 1 case ; group A and E was 1 case ; group C and E was 1 case ; group A, B and C was 1 case. There were no statistical significance in the 16 symptoms of autistic disorder of DSM-III-R between patients with chromosomal abnormalities and patients without chromosomal abnormalites. These results do not support the hypothesis that fragile X chromosome is an etiological factor in autistic disorder.

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Differential Spatial Modulation with Gray Coded Antenna (그레이 코드화된 안테나 순서의 차등 공간 변조)

  • Kim, Jeong-Su;Lee, Moon Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.17 no.5
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    • pp.51-59
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    • 2017
  • In this paper, we propose a gray code order of antenna index permutations for differential spatial modulation (DSM). To facilitate the implementation, the well-known Trotter-Johnson ranking and unranking algorithms are adopted, which result in similar computational complexity to the existing DSM that uses the lexicographic order. The signal-to-noise ratio gain achieved by the proposed gray code order over the lexicographic order is also analyzed and verified via simulations. Based on the gray coding framework, we further propose a diversity-enhancing scheme named intersected gray (I-gray) code order, where the permutations of active antenna indices are selected directly from the odd (or even) positions of the full permutations in the gray code order. From analysis and simulations, it is shown that the I-gray code order can harvest an additional transmit diversity order with respect to the gray code order.

Culture Conditions of Geobacillus kaustophilus DSM 7263 for Production of Thermophilic Extracellular Lipase (내열성 extracellular lipase 생산을 위한 Geobacillus kaustophilus DSM 7263의 배양조건)

  • Jeon, Sung-Jong;Kang, Hyun-Woo
    • Journal of Life Science
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    • v.20 no.6
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    • pp.902-906
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    • 2010
  • A producer of thermophilic extracellular lipase, Geobacillus kaustophilus DSM 7263, was selected from various microorganisms of the Geobacillus genus. We investigated optimum conditions for mass production of G. kaustophilus lipase. Among the different natural oil media, olive oil was optimal for enzyme production. The maximum amount of enzyme production was obtained when G. kaustophilus was grown in a medium containing 0.5% olive oil as a carbon source. The pH and temperature for optimal growth were pH 8.0 and $55^{\circ}C$, respectively, while the optimum pH and temperature for lipase production were pH 6.0 and $50^{\circ}C$, respectively. In the presence of $Mg^{2+}$ and $Mn^{2+}$, lipase production was dramatically enhanced by 247% and 157%, respectively, whereas enzyme production was inhibited by $Zn^{2+}$, $Cu^{2+}$, and $Cd^{2+}$. The addition of 0.1% (v/v) triton X-100 increased lipase production and cell growth when compared to the negative control.

Extracting 3D Geospatial Information Using SPOT 5 HRG Stereo Imagery (SPOT 5 HRG 스테레오 영상을 이용한 3차원 지형정보 추출)

  • Lee Jin-Duk;Jeong Tae-Sik;Yeon Sang-Ho
    • Proceedings of the Korea Contents Association Conference
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    • 2005.11a
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    • pp.335-339
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    • 2005
  • Digital elevation models(DEM) were generated from SPOT-5 HRG supermode imagery through photogrammetric processing. The reference DEMs were obtained from digital topographic maps of 1/5000 scaleas for analyzing the accuracy of the generated DEMs. The DEMs extracted from HRG stereo image data were compared with digital topograpic map DEMs on several test sections. And digital surface models(DSM) and 3D building model was produced.

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Radiofrequency Ablation Using a Separable Clustered Electrode for the Treatment of Hepatocellular Carcinomas: A Randomized Controlled Trial of a Dual-Switching Monopolar Mode Versus a Single-Switching Monopolar Mode

  • Jae Won Choi;Jeong Min Lee;Dong Ho Lee;Jung-Hwan Yoon;Yoon Jun Kim;Jeong-Hoon Lee;Su Jong Yu;Eun Ju Cho
    • Korean Journal of Radiology
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    • v.22 no.2
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    • pp.179-188
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    • 2021
  • Objective: This study aimed to prospectively compare the efficacy, safety, and mid-term outcomes of dual-switching monopolar (DSM) radiofrequency ablation (RFA) to those of conventional single-switching monopolar (SSM) RFA in the treatment of hepatocellular carcinoma (HCC). Materials and Methods: This single-center, two-arm, parallel-group, randomized controlled study was approved by the Institutional Review Board. Written informed consent was obtained from all patients upon enrollment. A total of 80 patients with 94 HCC nodules were randomized into either the DSM-RFA group or SSM-RFA group in a 1:1 ratio, using a blocked randomization method (block size 2). The primary endpoint was the minimum diameter of the ablation zone per unit time. The secondary endpoints included other technical parameters, complication rate, technique efficacy, and 2-year clinical outcomes. Results: Significantly higher ablation energy per unit time was delivered to the DSM-RFA group than to the SSM-RFA group (1.7 ± 0.2 kcal/min vs. 1.2 ± 0.3 kcal/min; p < 0.001). However, no significant differences were observed between the two groups for the analyzed variables, including primary endpoint, regarding size of the ablation zone and ablation time. Major complication rates were 4.9% in the DSM-RFA group and 2.6% in the SSM-RFA group (p = 1.000). The 2-year local tumor progression (LTP) rates of the HCC nodules treated using DSM-RFA and SSM-RFA were 8.5% and 4.7%, respectively (p = 0.316). The 2-year LTP-free survival rates of patients in the DSM-RFA and SSM-RFA groups were 90.0% and 94.4%, respectively (p = 0.331), and the 2-year recurrence-free survival rates were 54.9% and 75.7%, respectively (p = 0.265). Conclusion: Although DSM-RFA using a separable clustered electrode delivers higher ablation energy than SSM-RFA, its effectiveness failed to show superiority over SSM-RFA in the treatment of HCC.