• Journal of Chest Surgery
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• 제31권9호
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• pp.845-854
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• 1998

Background: S-2-(3 aminoprophlamino) ethylphosphorothioic acid(WR-2721) is one of the radical scavenging thiols. We tested its protective effects in the reperfused heart. Material and Method: The experimental setup was the constant pressure Langendorffs perfusion system. We investigated the radical scavenging properties of this compound in isolated rat hearts which were exposed to 20 minutes ischemia and 20 minutes reperfusion. Four experimental groups were used:group I, control, Amifostine 50 mg(1 mL) peritoneal injection 30 minutes before ischemia(group II), Amifostine 10 mg(0.2 mL) injection during ischemia through coronary artery(group III),and Amifostine 50 mg(1 mL) peritoneal injection 2 hrs before ischemia(group IV). The experimental parameters were the levels of latate, CK-MB, and adenosine deaminase(ADA) in frozen myocardium, the quantity of coronary flow,and left ventricular developed pressure, and it's dp/dt. Statistical analysis was performed using repeated measured analysis of variance and student t-test. Result: The coronary flow of group II and IV were less than group I and III at equilibrium state but recovery of coronary flow at reperfusion state of group II, III, and IV were more increased compared with group I. The change of systolic left ventricular devoloping pressure of group II and IV were less than control group at equilibrium state, which seemed to be the influence of the pharmacological hypotensive effect of amifostine. But it was higher compared with group I at reperfusion state. The lactic acid contents of group II were less than control group in frozen myocardium.(Group I was 0.20 0.29 mM/g vs Group II, which was 0.10 0.11 mM/g). The quantity of CK-MB in myocardial tissue was highest in group IV (P=0.026 I: 120.0 97.8 U/L vs IV: 242.2 79.15 U/L). The adenosine deaminase contents in the coronary flow and frozen myocardium were not significantly different among each group. Conclusion: Amifostine seemed to have significant cardioprotective effect during ischemia and reperfusion injuries of myocardium.

• 한국식품과학회지
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• 제28권1호
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• pp.146-151
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• 1996

6종류의 알긴산을 기질로하여 효소 반응을 시켜 알긴산 올리고당 제조를 시도한 결과, 실험에 사용한 효소의 경우 G-rich block에만 특이하게 작용하는 guluronate lyase 일종으로 G-block에 주로 작용하여 올리고당을 생성하는 것으로 확인되었다. 또한 4종류의 시판 알긴산중에서도 1종(Wako Co.)의 Na-alginate에 대해서 특이하게 6-7개의 올리고당 spot가 TLC에서 확인되었고, 그외 3종의 Na-alginate는 2-4개 정도의 올리고당 spot가 TLC에 나타났다. 6-7개의 spot가 확인된 Na-alginate(Wako Co.)를 기질로 대량 분해시킨 후 Sephadex G-25 및 Bio-gel p-2로 분획, 정제를 행하고 중합도를 측정하여 올리고당을 확인한 결과, 중합도가 각각 다른 4개의 올리고당을 확인할 수 있었다.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 1999년도 추계 학술발표회 논문집 Proceedings of EESK Conference-Fall
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• pp.52-57
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• 1999

Korea Earthquake Monitoring System(KEMS) in the Korea Institute of Geology Mining and Materials(KIGAM) as detected more than 1000 events since the end of 1998. But not all events are interpreted as earthquakes because many events are concentrated on daytime. It strongly implies that in addition to earthquake these events include artificial effects such as industrial blasting. Before the determination of eathquake charactertistics in the korean peninsula it is necessary to discriminate the detected events as earthquakes or artificial events. For the discriminant study KIGAM and SMU(Southern Methodist University) installed a triangular four-element 1-km aperture seismo-acoustic array at Chul-Won area northeast of Seoul Korea. Each array element includes a GS-13 seismometer in the bottom of borehole and a Validyne DP250-14 microbarometer sensor mounted inside of the borehole 1,2 meter deep connected to a 11 arm radial array of 10m porous soaker hoses. This array introduce the use of 2.4-GHz radios for inter-array self-contained solar-charged power system and GPS time-keeping system. A 24-bit digital data acquisition system performs 40 SPS in the infrasound and seismometer data. Velocity and direction of wind and temperature are also measured at hub site and included to the data stresam. This seismo-acoustic array will be used to identify and locate associated with industrial blasting and these identified and located events will be applied to form a ground truth database useful to assist the other development of discriminant studies.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2016년도 학술발표회
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• pp.17-17
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• 2016

이중편파 레이더는 수평 수직반사도($Z_H{\cdot}Z_V$), 차등반사도($Z_{DR}$), 교차상관계수(${\rho}_{HV}$), 차등위상차(${\Phi}_{DP}$) 등 다양한 변수 산출을 통하여 대기 수상체 구분, 우적분포에 영향이 적은 강우량 추정, 밝은 띠(BB, Bright Band)의 탐지 등이 가능하게 됨으로써 수문기상 및 재해관리 분야에 활용성이 점점 더 커지고 있다. 본 연구는 RHI, PPI에서 생산된 레이더 변수를 이용하여 BB를 탐지하고 그 특성을 평가하였다. BB는 레이더를 이용하여 상층대기를 관측할 때 수직단면에서 강수입자가 눈에서 비로 변하는 구간에서 과대하게 높은 반사도가 나타나는 층을 말한다. BB에서는 QPE가 과대 추정되기 때문에, BB의 특성 파악은 레이더의 관측전략 수립과 QPE 보정에 필수적이다. 본 연구에서는 RHI에 의한 $Z_H$의 연직단면분석, RHI와 PPI의 고도각 경사거리(slant range) 빔의 ${\rho}_{HV}$, $Z_{DR}$, $Z_H$에 의한 분석을 통하여 BB의 상단부($BB_{TOP}$), 최정점($BB_{PEAK}$) 및 하단부($BB_{BOTTOM}$)의 고도를 상호 비교 평가하였다. 분석 자료는 KICT X-밴드 레이더에 의한 관측한 2015년 10월 21일의 층상운에 의한 강우를 이용하였다. RHI에 의한 $Z_H$의 연직단면 분석결과 $BB_{top}$, $BB_{bottom}$ 및 $BB_{peak}$는 KICT 레이더 고도(MSL : 40m)를 기준으로 각각 3.26Km, 2.3Km($BB_{width}$: 0.96km) 및 2.7Km로 나타났다. 이 같은 결과는 다른 2가지 분석방법에서도 유사하게 나타나고 있으며, 이는 BB분석을 위해 다양한 변수를 통한 신뢰성 있는 BB의 특성을 파악할 수 있는 기반을 제공한다.

• International Journal of Naval Architecture and Ocean Engineering
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• 제7권6호
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• pp.1044-1055
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• 2015

DPCap analysis can assist in determining the maximum environmental forces the DP system can counteract for a given heading. DPCap analysis results are highly affected by the thrust forces provided by the thrust system which consists of several kinds of thrusters. The thrust forces and moment are determined by the maximum thrust of the thrusters as well as the thruster configuration. In this paper, a novel local optimization of thruster configuration based on a synthesized positioning capability criterion is proposed. The combination of the discrete locations of the thrusters forms the thruster configuration and is the input, and the synthesized positioning capability is the output. The quantified synthesized positioning capability of the corresponding thruster configuration can be generated as the output. The optimal thruster configuration is the one which makes the vessel has the best positioning capability. A software program was developed based on the present study. A local optimization of thruster configuration for a supply vessel was performed to demonstrate the effectiveness and efficiency of the program. Even though the program cannot find the global optimal thruster configuration, its high efficiency makes it essentially practical in an engineering point. It may be used as a marine research tool and give guidance to the designer of the thrust system.

• 수산해양교육연구
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• 제24권4호
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• pp.494-506
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• 2012

The purpose of this study was to analyse 3, 4, 5-year-old children's private speech according to their age and task characteristics (structured task vs. unstructured task). In order to achieve the goal, the main effect of age, characteristic of tasks and interaction effect were considered among age and characteristic of tasks on preschool children's private speech. The subjects were each 30 3, 4, 5-year-olds from preschool in Busan, South Korea. The structured task was puzzle task and the unstructured task was drawing task from TCT-DP. The data was analyzed by repeated measurement two way ANOVA: 3(age) ${\times}$ 2((characteristic of task). As a result, firstly, total private speech of 4-year-old was higher than 3-year-old, 5-year-old in both tasks, and total private speech of 5-year-old was higher than 3-year-old in both tasks. Secondly, the task-irrelevant private speech was not affected by main effect of age and characteristic of task and interaction effect between age and characteristic of task. Thirdly, the task-relevant private speech was received both main effects and interaction effects between age and characteristic of task. Finally, the external manifestation of inner speech were not received effect of age but received effect of characteristic of task, and received interaction effect between age and characteristic of task. The results of this study imply that characteristic of task is an important factor inducing children's private speech.

• 소성∙가공
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• 제31권6호
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• pp.351-364
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• 2022

The yield criterion, or called yield function, plays an important role in the study of plastic working of a sheet because it governs the plastic deformation properties of the sheet during plastic forming process. In this paper, we propose a modified version of previous anisotropic yield function (Trans. Mater. Process., 31(4) 2022, pp. 214-228) based on J2 and J3 stress invariants. The proposed anisotropic yield model has the 6th-order of stress components. The modified version of the anisotropic yield function in this study is as follows. f(J₂⁰,J₃⁰) ≡ (J₂⁰)³ + α(J₃⁰)² + β(J₂⁰)^3/2 × (J₃⁰) = k⁶ The proposed anisotropic yield function well explains the anisotropic plastic behavior of various sheets such as aluminum, high strength steel, magnesium alloy sheets etc. by introducing the parameters α and β, and also exhibits both symmetrical and asymmetrical yield surfaces. The parameters included in the proposed model are determined through an optimization algorithm from uniaxial and biaxial experimental data under proportional loading path. In this study, the validity of the proposed anisotropic yield function was verified by comparing the yield surface shape, normalized uniaxial yield stress value, and Lankford's anisotropic coefficient R-value derived with the experimental results. Application for the proposed anisotropic yield function to AA6016-T4 aluminum and DP980 sheets shows symmetrical yielding behavior and to AZ31B magnesium shows asymmetric yielding behavior, it was shown that the yield locus and yielding behavior of various types of sheet materials can be predicted reasonably by using the proposed anisotropic yield function.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권6호
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• pp.2964-2985
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• 2019

Global data center IP traffic is expected to reach 20.6 zettabytes (ZB) by the end of 2021. Intra-data center networks (Intra-DCN) will account for 71.5% of the data center traffic flow and will be the largest portion of the traffic. The understanding of traffic distribution in IntraDCN is still sketchy. It causes significant amount of bandwidth to go unutilized, and creates avoidable choke points. Conventional transport protocols such as Optical Packet Switching (OPS) and Optical Burst Switching (OBS) allow a one-sided view of the traffic flow in the network. This therefore causes disjointed and uncoordinated decision-making at each node. For effective resource planning, there is the need to consider joining the distributed with centralized management which anticipates the system's needs and regulates the entire network. Methods derived from Kalman filters have proved effective in planning road networks. Considering the network available bandwidth as data transport highways, we propose an intelligent enhanced SDN concept applied to OBS architecture. A management plane (MP) is added to conventional control (CP) and data planes (DP). The MP assembles the traffic spatio-temporal parameters from ingress nodes, uses Kalman filtering prediction-based algorithm to estimate traffic demand. Prior to packets arrival at edges nodes, it regularly forwards updates of resources allocation to CPs. Simulations were done on a hybrid scheme (1+1) and on the centralized OBS. The results demonstrated that the proposition decreases the packet loss ratio. It also improves network latency and throughput-up to 84 and 51%, respectively, versus the traditional scheme.

• Tribology and Lubricants
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• 제35권4호
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• pp.206-214
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• 2019

This study investigates alternative refrigerants and refrigerant oils as well as the tendency of protecting the global environment in view of automobile air-conditioning systems. Since decades, the R12 refrigerant is not used in automobile air-conditioners because of the ozone depletion potential (ODP) problem, and for the last 20 years, the ODP-free R134a refrigerant is leading the new automotive air-conditioning market. However, owing to its high global warming potential (GWP), the R134a refrigerant use in automobile air-conditioning system is also prohibited by law, and alternative refrigerants with a low GWP need to be proposed. Therefore, recently, the application of R1234yf, R152a, or other alternative refrigerants has started worldwide. By contrast, natural refrigerant R744 was introduced in the market several years ago by VDA (Verband Der Automobilindustrie), which is a German association in the automotive industry. This study also deals with refrigerant oils. For a long time, polyalkylene glycol (PAG) oil has been traditionally used with automobile air-conditioners, and polyolester (POE) oil is suitable for HEV, PHEV, and EV air-conditioning systems, where it is used by the electrically driven compressor owing to its excellent electrical insulation properties. Finally, PAG is an excellent lubricant for all the R134a, R152a, R1234yf, and R744 refrigerants, and has the advantage that it can be applied rapidly to alternative refrigerant air-conditioning systems.

• 한국동물생명공학회지
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• 제34권1호
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• pp.2-9
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• 2019

Because mesenchymal stem cells (MSCs) maintain distinct capacities with respect to self-renewal, differentiation ability and immunomodulatory function, they have been highly considered as the therapeutic agents for cell-based clinical application. Of particular, differentiation condition alters characteristics of MSCs, including cellular morphology, expression of gene/protein and cell surface molecule, immunological property and apoptosis. However, the previous results for differentiation-related apoptosis in MSCs have still remained controversial due to varied outcomes. Therefore, the present study aimed to disclose periodical alterations of pro- and anti-apoptosis in MSCs under differentiation inductions. The human dental pulp-derived MSCs (DP-MSCs) were differentiated into adipocytes and osteoblasts during early (1 week), middle (2 weeks) and late (3 weeks) stages, and were investigated on their apoptosis-related changes by Annexin V assay, qRT-PCR and western blotting. The ratio of apoptotic cell population was significantly (p < 0.05) elevated during the early to middle stages of differentiations but recovered up to the similar level of undifferentiated state at the late stage of differentiation. In the expression of mRNA and protein, whereas expressions of pro-apoptosis-related makers (BAX and BAK) were not altered in any kind and duration of differentiation inductions, anti-apoptosis marker (BCL2) was significantly (p < 0.05) elevated even at the early stage of differentiations. The recovery of apoptotic cell population at the late stage of differentiation is expected to be associated with the response by elevation of anti-apoptotic molecules. The present study may contribute on understanding for cellular mechanism in differentiation of MSCs and provide background data in clinical application of MSCs in the animal biotechnology to develop effective and safe therapeutic strategy.