• Title/Summary/Keyword: DK 537

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Characteristics and Yield of Recommended Cultivars by Imported Forage Crop Regional Yield Trials in 2002 I. Early Maturing, Good Qualify, and High Yield of Forage Corn Hybrid, “DK 537 (2002년 사료작물 수입적응성 인증품종의 생육기성 및 수동성 1. 조숙 양질 다수성 사료작물 옥수수 교잡종 “DK 537”)

  • Sung, B.R.;Choi, G.J.;Lim, Y.W.;Lim, Y.C.;Park, K.J.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.4
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    • pp.247-252
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    • 2002
  • “DK 537”has been selected by forage crop breeding team at the National Livestock Research Institute(NLRI), RDA and has been determined by the Deliberative Council of the National Agricultural Cooperative Federation(NACF) in 2002, as a new recommended hybrid which is early maturing, good quality and hi호 yield of corn for silage. The characteristics of this hybrid are as follows ; 1. The seed coat is yellow and the mean of tasseling date is 5th of July, included in early maturing hybrid which is one day delayed than check cultivar, DK 501. The culm length is 246cm. It is resistant to lodging because of its low height from surface to ear. 2. DK 537 shows resistance to H. maydis and Maize Black-Streaked Dwarf Virus(MBSDV). It also shows strength to corn borer as much as DK 501 does. 3. Fresh yield. dry matter yield. and TDN per a ha are 50 tons, 16.9 tons, and 11.4 tons respectively. which are almost same yielding level of DK 501. Its percent ear to total dry matter is 50.8% at the same time. Through all these tests, we could make sure at DK 537 hybrid will be recommended as good forage crop.

Acute and Genetic Toxicity Study of DK1002, a Drug Candidate for Analgesics (DK1002에 대한 급성독성시험 및 유전독성에 관한 연구)

  • Ryu, Jae-Chun;Kim, Kyung-Ran;Kim, Hyun-Joo;Jung, Sang-Oun;Kim, Myung-Kuk;Park, Hee-Sock;Kim, Yong-Hae
    • Toxicological Research
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    • v.14 no.3
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    • pp.427-433
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    • 1998
  • The acute and genetic toxicity of DK1002 was subjected in this study. DK1002 which is a morphine-like new drug candidate synthesized by Dong-Kook Pharmaceutical Co. Ltd. is now under developing as a analgesics that have better drug efficacy and least addictive property. In acute toxicity study, the 50% lethal doses ($LD_{50}$) of DK1002 were determined as>2000mg/kg (p.o.), 237.0mg/kg(i.p.), 57.5mg/kg(i.v.), and 1266.9mg/kg (s.c.). And also, to study the genotoxicity of DK1002, we performed bacterial reversion assay with Salmonella typhimurium TA98, TA100, TA1535, and TA1537, and in vitro chromosomal aberration assay with Chinese hamster lung cells in the presence and absence of S-9 metabolic activation system. In vivo micronucleus assay using mouse bone marrow cells was also performed. From these results, DK1002 was revealed nonmutagenic potential in S. typhimurium TA98, TA100, TA1535, and TA537 both in the absence and presecne of metablic activation system. No clastogenicity of DK1002 was observed in chromosomal aberration assay in vitro as well as in micronucleus assay in vivo.

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