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The Differences of Serum Homocysteine Levels in Mild Cognitive Impairment and Dementia of Alzheimer's Type with or without Depressive Symptoms (경도인지장애, 알쯔하이머형 치매 환자에서 우울증상 유무에 따른 혈중 호모시스테인의 차이)

  • Hwangbo, Ram;Kim, Hyun;Lee, Kang Joon
    • Korean Journal of Psychosomatic Medicine
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    • v.22 no.1
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    • pp.40-45
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    • 2014
  • Objectives : Mild cognitive impairment(MCI) and dementia of Alzheimer's type(AD) are characterized by progressive decline of cognitive abilities and a wide range of neuropsychiatric symptoms like depression. Among various diagnostic tools of AD, many studies showed that elevated levels of serum total homocysteine are associated with increased risk of developing Alzheimer's disease, depression and other neuropsychiatric disorders. We investigated whether elevated homocysteine concentrations are associated with depressive symptoms in MCI and AD. Methods : A total of 86 patients diagnosed with MCI or AD participated. Total serum homocysteine levels in fasting blood samples were measured. We examined cognitive symptoms by MMSE-KC, Global Deterioration Scale(GDS), Clinical dementia rating(CDR) and depressive symptoms by Korean version of Geriatric Depression Scale(K-GDS). Results : The total serum homocysteine levels were significantly higher in MCI with depression than in MCI without depression. There was no significant difference in the mean homocysteine levels between AD patients with depression and AD patients without depression. The total homocysteine levels showed a negative correlation with MMSE-KC and a positive correlation with CDR, GDS. Conclusions : These findings suggest that elevated homocysteine level is a risk factor for the decline of cognitive function and depression. We found a significant relationship between elevated serum homocysteine level and depressive symptoms in MCI. But our study had several limitations, thus more research is needed to confirm this finding.

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A Study on Conservation Management Systems based on Deterioration Diagnosis of the Fossil Site: Tracksite of Dinosaurs and Pterosaurs in Sanbuk-dong, Gunsan, Korea (화석지 손상도 정밀진단 기반 보존관리체계 연구: 군산 산북동 공룡발자국과 익룡발자국 화석산지)

  • Hye Ri Yang;Gyu Hye Lee;Chan Hee Lee
    • Economic and Environmental Geology
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    • v.56 no.6
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    • pp.675-695
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    • 2023
  • The tracksite of dinosaurs and pterosaurs in Sanbuk-dong of Gunsan is the largest early Cretaceous dinosaur footprint fossil site in Korea, and all the footprints are important evidence indicating that large ornithopod and theropod dinosaurs inhabited the Korean peninsula during the early Cretaceous. The Sanbuk-dong site was covered with waterproof sheet in an outdoor environment until the installation of a protective enclosure in 2021. As a result, various factors such as shear force, load reduction, temperature and humidity fluctuations, acid rain, salinity and microorganisms have complexly interacted in the substrate of fossils, exacerbating the damage to footprints. For 159 footprints in 12 trackways among the footprints found in the site, the damage types were classified in detail and the level of each damage was assessed. The damages were classified into 6 types through the classification of deterioration degree of individual footprints. As a result of ultrasonic physical property evaluation on the surface of the fossil site, most of these footprints are in the completely weathered (CW) stage. Furthermore, various weathering patterns were observed in the study area, and surface contaminants were analyzed along the stratigraphy. Although the patterns of freshness and contaminants varied at different points within the fossil site, the chemical compositions were similar. Based on the results, an efficient conservation management system for dinosaur footprint fossils was established, and a conservation treatment type for each footprint was proposed.

A Study on Damage State Criteria based on Capacity Spectrum of Piloti-type RC Shear Wall Structures (필로티형 콘크리트 전단벽 구조물의 능력스펙트럼기반 손상도 기준에 대한 연구)

  • Hwang, Ji-Hyun;Park, Ki-Tae;Park, Tae-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.10
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    • pp.5199-5205
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    • 2013
  • Despite the increasing incidence of earthquakes in recent years, many of the existing buildings don't have appropriate seismic performance due to the deterioration or structural characteristics. In particular, a piloti-type RC shear wall structure, which is one of the building types in Korea, is highly vulnerable to earthquakes due to a great lack of shear function that can resist lateral force caused by the earthquake since the first floor is mostly soft story, and it is classified as weak story. In this regard, a study on the damage state criterion for the piloti-type RC shear wall structures was carried out. The capacity spectrum was calculated through the structural analysis by selecting typical type of buildings of shear wall systems, and damage state criterion was defined based on the shape of the capacity spectrum.

Management of Vocal Cord Palsy during Thyroid Surgery (갑상선 수술 시의 성대마비의 처치)

  • Choi Hong-Shik;Kim Se-Heon;Park Kuk-Jin;Kim Kwang-Moon;Hong Won-Pyo
    • Korean Journal of Head & Neck Oncology
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    • v.14 no.1
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    • pp.27-34
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    • 1998
  • Objectives, Materials & Methods: To prevent deterioration of postoperative voice due to iatrogenic transection of the recurrent laryngeal nerve during the thyroid surgery, intraoperative medialization of the membranous vocal cord by type I thyroplasty together with direct epineurial neurorraphy was done on 2 cases of benign thyroid lesion. To improve the quality of voice together with complete removal of advanced thyroid carcinoma, intraoperative vocal cord medialization on the lesion side together with total thyroidectomy was done by type I thyroplasty in 2 cases and combined procedure by arytenoid adduction and type I thyroplasty in another 2 cases. Results: The resultant voice of the iatrogenic injury cases was relatively tolerable. The voice of the combined procedure was better than that of type I thyroplasty cases for the intraoperative rehabilitation cases. Not only for the preoperative evaluation of the severity of the nerve lesion but also the prognosis will be expected by use of laryngeal EMG in the cases of thyroid cacer with vocal cord palsy. Conclusion: Intraoperative simultaneous rehabilitation for the vocal cord palsy during thyroid surgery is beneficial for the patients.

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An Analysis of Vegetation Status in an Urban Natural Park -Focus on Seoo Royal Tomb-

  • Kang, Hyun-Kyoung;Bang, Kwang-Ja;Kim, Hyun
    • Journal of the Korean Institute of Landscape Architecture International Edition
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    • no.1
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    • pp.13-25
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    • 2001
  • Recently there have been increasing demands and desire for the urban open space due to urban development or environmental deterioration. Urban natural parks in Seoul provide citizens with comfortable open space and thus play an important role as learning spaces to experience nature and understand the environment. Accordingly, this study aims to analyze existing vegetation and provide basic data for the conservation and management plans of urban natural parks and education programs. The contents of the study encompass natural environment such as topography, altitude, slope and aspect and botanical ecosystem including the structure of plant communities and tree growth. According to the result of topography analysis, the overall altitude was not high but the slope was relative steep. Vegetation of Seoo Royal Tomb, a urban natural park has been classified into 12 types, and they include; Quercus acutissima community(lowland type), Quercus acutissima community(valley type), quercus variabilis community, Quercus mongolica community, Castanea crenata community, Capinus laxiflora community, Pinus densiflora community(lowland type), Pinus densiflora community(slope type), Robinia pseudo-acacia community, Populos$\times$albaglandulosa community, Pinus rigida community, and Pinus koraiensis community. Based on the survey and analysis results, we have classified the study area into conservation, buffer, and utilization zones for the effective management. This study provides basic data to support the establishment of master plans for urban natural parks by analyzing vegetation conditions at Seoo Royal Tomb, an urban natural park, Based on the results presented in the study, consistent monitoring work needs to be conducted, and elaborate management plans also should be prepared.

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Fatigue performance of a new type PSC girder (신형식 PSC거더의 피로 성능)

  • Choi, Sang-Hyun;Lee, Chang-Soo;Kim, Tae-Kyun;Eui, Chul-Soo
    • Proceedings of the KSR Conference
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    • 2011.05a
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    • pp.965-972
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    • 2011
  • Unlike metallic materials, the importance of fatigue performance of concrete has been ignored. However, it is reported that environmental effects, if it cause deterioration, may increase the risk of fatigue failure under repeated loadings. In case of railroad bridges, the risk may increase due to highly periodic, repetitive, heavier nature of train load, which runs through the fixed passage called the track. Especially, when new material or structure is implemented for a main bridge member, experimental validation should be performed to avoid damage or failure due to unexpected behavior. In this paper, the fatigue performance of an IT girder is examined via a repeated loading test. The IT girder is a new type of a prestressed concrete (PSC) girder with two prestressed H-beams in the top of the girder, which provide additional sectional capacity, and it can be applied to the span longer than 30m which is a typical limit for a usual PSC girder. To obtain the fatigue performance, a 10m IT girder specimen is designed, and a repeated load test is performed by applying the cyclic load two million times. The fatigue performance of the girder is examined according to the Japanese and the CEB-FIB design codes. The fatigue test result shows that the IT girder satisfies both design codes.

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A Study on the Restoration of Paintworks on the Signboard of Paldalmun Gate during the Jeongjo er (정조연간 팔달문 현판의 단청 복원에 관한 연구)

  • Kim, Suk-Hyun;Koo, Bon-Nung
    • Journal of architectural history
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    • v.29 no.3
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    • pp.51-66
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    • 2020
  • Paldalmun gate was built in 1794 as the southern gate of Suwon Hwaseong. The signboard's paintworks of Paldalmun gate was applied to the signboard of the state-run building in the 18th century. The signboard of Paldalmun gate was repainted along with the building when repaired in 1969. In that time, the signboard's paintworks during the reign of Jeongjo era was transformed. The purpose of this study is to restore the image of Jeongjo era paintworks on the Paldalmun's signboard, which has been modified since the 1960s due to modification. For the purpose of the examination, we examined the traces of paintworks remaining on the signboard of Paldalmun gate and examined several state-run signboards decorated with 'Yukhwamoon' paintings similar as the signboard of Paldalmun gate, which made around the 18th century. Through the above-mentioned researches, typical color features were identified in the decorated with 'Yukhwamoon' paintings on signboard in the 18th and 19th centuries. In addition, the type of pigment used in the signboard's paintwork of Paldalmun gate was verified through the 『Hwaseong Seongyeok Uigwe(華城城役儀軌)』 and the 『Han-gul Jeongri Uigwe(한글整理儀軌)』, while analyzing the characteristics of age-related deterioration according to the type of paintworks in various traces of pigment coatings remaining on the signboard of Paldalmun gate.

The Forecasting Model of the Repair Cost in Apartment Housing - Focused roof water proofing and Elevator work - (공동주택 공종별 수선비용 예측모델 연구 - 옥상방수 공사와 승강기 공사를 중심으로 -)

  • Lee, KangHee;Chae, ChangU
    • KIEAE Journal
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    • v.15 no.6
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    • pp.63-68
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    • 2015
  • Purpose: Most if buildings need various repair works for preventing or delaying the deterioration which gives rise to affect the living condition or function after constructed. Therefore, a long-term repair schedule should be planned and a repair cost is required. In this paper, it aimed at providing the statistical forecast model for a repair cost in roof water-proofing work and elevator work using statistical approach with three variables such as number of household, management area and a elapsed year. Data are collected in apartment housings which are located in Seoul area and conducted with interview and questionnaire sheet. Each analyzed work is divided into a partly work and fully work. Results of this study are shown that, first, the regression model takes a multiplying type like a Cobb-Douglas function and is changed into the log-linear type to include the three variable simultaneously. Second, the goodness-of-fit of the repair cost forecasting model has a good statistics in determinant's coefficient and Dubin-Watson value. Third, the management area is stronger factor than other the number of household and an elapsed year in roof water-proofing work and elevator work.

shear Tests on female-to-female Type Joint between Precast Concrete Bridge Decks (프리캐스트 콘크리트 교량바닥판 female-female이음부의 전단실험)

  • 김영진;김영진;김종희
    • Magazine of the Korea Concrete Institute
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    • v.10 no.6
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    • pp.161-168
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    • 1998
  • Increase of traffic volume in recent years results in deterioration of the bridge slab, which is directly subjected ot vehicle loads. Where extensive repair is necessary, replacement or enhancement of load carrying capacity using full depth precast concrete deck is often the most practical solution. Precast deck system has transverse joints between adjacent precast decks. Vertical shear forces occur when a vehicle wheel load is carried by precast decks and the joints are used to transfer the load to an adjacent deck. Effective load transfer between precast decks is critical for integral behavior. Finite element analysis and tests were run on the proposed femal-to-female type joint. 18 joint specimens were tested to investigate the effects of angle. D/H, and confining stress under static load. Results indicate joint with angle of 60$^{\circ}$ and D/H of 1/4 shows the improved load carrying capacity on crack. It is effective in protecting the cracking of joints to keep the joint in compression using confining stress.

Measurement of the Volumetric Thermal Errors for CNC Machining Center Using the Star-type-styluses Tough Probe

  • Lee, Jae-Jong;Yang, Min-Yang
    • International Journal of Precision Engineering and Manufacturing
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    • v.1 no.1
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    • pp.111-117
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    • 2000
  • One of the major limitations of productivity and quality in metal cutting is the machining accuracy of machine tools. The machining accuracy is affected by geometric errors, thermally-induced errors, and the deterioration of the machine tools. Geometric and thermal errors of machine tools should be measured and compensated to manufacture high quality products. In metal cutting, the machining accuracy is more affected by thermal errors than by geometric errors. This paper models the thermal errors for error analysis and develops an on-the-machine measurement system by which the volumetric errors are measured and compensated. The thermal error is modeled by means of angularity errors of a column and thermal drift error of the spindle unit which are measured by the touch probe unit with a star type styluses and a designed spherical ball artifact (SBA). Experiments show that the developed system provides a high measuring accuracy, with repeatability of $\pm$2$\mu\textrm{m}$ in X, Y and Z directions. It is believed that the developed measurement system can be also applied to the machine tools with CNC controller. In addition, machining accuracy and product quality can be also improved by using the developed measurement system when the spherical ball artifact is mounted on a modular fixture.

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