• Title/Summary/Keyword: DCs

Search Result 1,510, Processing Time 0.028 seconds

In vivo Dendritic Cell Migration Tracking Using Near-infrared (NIR) Imaging (Near-infrared (NIR) 영상기법을 이용한 생체 내 수지상세포의 이동)

  • Lee, Jun-Ho;Jung, Nam-Chul;Lee, Eun Gae;Lim, Dae-Seog
    • KSBB Journal
    • /
    • v.27 no.5
    • /
    • pp.295-300
    • /
    • 2012
  • Matured dendritic cells (DCs) begin migration with their release from the bone marrow (BM) into the blood and subsequent traffic into peripheral lymphoid and non-lymphoid tissues. Throughout this long movement, migrating DCs must apply specialized skills to reach their target destination. Non-invasive in vivo cell-tracking techniques are necessary to advance immune cell-based therapies. In this study, we used a DiD cell-tracking solution for in vivo dendritic cell tracking in naive mice. We tracked DiD (non-invasive fluorescence dye)-labeled mature dendritic cells using the Near Infrared (NIR) imaging system in normal mice. We examined the immunophenotype of DiD-labeled cells compared with non-labelled mature DCs, and obtained time-serial images of NIR-DC trafficking after mouse footpad injection. In conclusion, we confirmed that DiD-labeled DCs migrated into the popliteal lymph node 24 h after the footpad injection. Here, these data suggested that the cell tracking system with the stable fluorescence dye DiD was useful as a cell tracking tool to advance dendritic cell-based immunotherapy.

CS-RANSAC Algorithm using Machine Learning Technique (머신러닝 기법올 적용한 CS-RANSAC 알고리즘)

  • Ko, Seunghyun;Yoon, Ui-Nyoung;Alikhanov, Jumabek;Jo, Geun-Sik
    • Proceedings of the Korea Information Processing Society Conference
    • /
    • 2016.10a
    • /
    • pp.632-635
    • /
    • 2016
  • 증강현실에서 영상과 증강된 콘텐츠 간의 이질감을 줄이기 위해서 정확한 호모그래피 행렬을 추정해야 하며, 정확한 호모그래피 행렬을 추정할때 RANSAC 알고리즘이 널리 사용된다. 그러나 RANSAC 알고리즘은 랜덤 샘플링 과정을 반복적으로 거치기 때문에 불필요한 연산 과정이 발생하고 이로 인해 알고리즘의 효율이 저하된다. 이러한 단점을 극복하기 위해 DCS-RANSAC 알고리즘이 제안되었다. 제안된 DCS-RANSAC 알고리즘은 이미지를 특징점 분포 패턴에 따라 그룹으로 분류하고 각 그룹에 제약조건 문제를 적용하여 불필요한 연산 과정을 줄이고 정확도를 향상시킨 알고리즘이다. 그러나 DCS-RANSAC 알고리즘에서 사용된 이미지 그룹 데이터는 수동적인 방법을 통해 직관적으로 분류되어 있지만 특징점 분포 패턴이 다양하지 않아 분류시 정확도가 저하되는 경우가 있다. 위의 문제점을 해결하기 위해 본 논문에서는 머신러닝 기법을 통해 이미지들을 자동으로 분류하고 각 그룹마다 각기 다른 제약조건을 적용하는 MCS-RANSAC 알고리즘을 제안한다. 제안하는 알고리즘은 머신러닝 기법을 사용하여 전처리 단계에서 이미지를 분류하고 분류된 이미지에 제약조건을 적용시켜 알고리즘의 처리시간을 줄이고 정확도를 향상시켰다. 실험 결과 본 논문에서 제안하는 MCS-RANSAC은 DCS-RANSAC 알고리즘에 비해 수행시간이 약 6% 단축되었고 호모그래피 오차율은 약 15% 줄어들었으며 참정보 비율은 2.8% 증가한 것으로 확인되었다.

Cortical Activation in the Human Brain induced by Transcranial Direct Current Stimulation (경두개 직류전류 자극이 대뇌피질의 뇌 활성도에 미치는 영향)

  • Kwon, Yong-Hyun;Kim, Chung-Sun;Jang, Sung-Ho
    • The Journal of Korean Physical Therapy
    • /
    • v.21 no.4
    • /
    • pp.73-79
    • /
    • 2009
  • Purpose: Recently, neurostimulation studies involving manipulation of cortical excitability of the human brain have been increasingly attempted. We investigated whether transcranial direct current stimulation (tDCS) applied to the underlying cerebral cortex, directly induces cortical activation during fMRI scanning. Methods: We recently recruited five healthy subjects without a neurological or psychiatric history and who were right-handed, as verified by the modified Edinburg Handedness Inventory. fMRI was done while constant anodal tDCS was delivered to the underlying SM1 area?? immediately after the pre-stimulation for eighteen minutes. Results: Group analysis yielded an averaged map that showed that the SM1 area and the superior parietal cortex in the ipsilateral hemisphere were activated. The voxel size and peak intensity were, respectively, 82 and 5.22 in the SM1, and 85 and 5.77 in the superior parietal cortex. Conclusion: Cortical activation can be induced by constant anodal tDCS of the underlying motor cortex. This suggests that tDCS may be an effective therapeutic device for enhancing? physical motor function by modulating neural excitability of the motor cortex.

  • PDF

B-DCS Fiber-Optic Network Design Algorithm Considering Network Survivability (생존도가 보장된 B-DCS 광전송망 설계 알고리즘)

  • 이인행;이영옥;정순기
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.24 no.12A
    • /
    • pp.1899-1909
    • /
    • 1999
  • Considering survivability in fiber-optic transmission networks using B-DCS(Broadband Digital Cross-connect System), a network design problem consists of WCAP(Working Channel Assignment Problem) and SCAP(Spare Channel Assignment Problem). WCAP has not been studied intensively as a part of a network design problem to minimize total network cost while SCAP has been studied in the several papers as an independent problem. In this study, we developed a WSCAP(Working and Spare Channel Assignment Problem) algorithm which is to minimize the total number of spare channels and working channels. After problem description, an IP(Integer Programming) model is formulated and several heuristic algorithms are presented. Finally, the result of a case study is described.

  • PDF

Successful TAE after DCS for Active Arterial Bleeding from Blunt Hepatic Injury in a Child: A Case Report

  • Park, Chan Ik;Lee, Sang Bong;Yeo, Kwang Hee;Lee, Seungchan;Park, Sung Jin;Kim, Ho Hyun;Kim, Jae Hun;Kim, Chang Won;Park, Chan Yong
    • Journal of Trauma and Injury
    • /
    • v.29 no.2
    • /
    • pp.47-50
    • /
    • 2016
  • Transcatheter arterial embolization (TAE) for blunt hepatic injury in children is not common and is especially rare after damage control surgery (DCS). We report a successful TAE after DCS on a child for massive bleeding from the left hepatic artery due to a motor vehicle accident. The car (a sport utility vehicle) ran over the chest and abdomen of a 4-year-old boy. On arrival, initial vital signs were as follows: blood pressure, 70/40 mmHg; heart rate, 149/min; temperature, $36.7^{\circ}C$; respiratory rate, 38/min. After resuscitation, computed tomography was done, and a suspicious contrast leakage from a branch of the left hepatic artery and a spleen injury (grade V) were found. TAE was performed successfully after DCS for a liver injury.

A Signaling Processor IC for Land Mobile Radio System (육상 이동 라디오 시스템용 호처리기 IC)

  • 전형근;김종문;송호준
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.24 no.10A
    • /
    • pp.1588-1596
    • /
    • 1999
  • This paper describes a signaling processor IC for land mobile radio systems. This IC generates CTSS tone or DCS code signals for signaling between the land mobile radio systems and decodes them to open the audio path. The CTSS tone or DCS code signals occupy the subaudio band and are transmitted with voice signal. The audio and subaudio paths consist of switched capacitor filters. The IC has been implemented in 0.6-$\mu\textrm{m}$ 2-poly 3-metal CMOS process. The chip size is 3 mm$\times$4.3 mm and total current is about 3.4 ㎃ at 3.3 V.

  • PDF

Design of a Multiband MIMO Antenna for USB Dongle Application (USB Dongle에 적용을 위한 다중 대역 MIMO 안테나 설계)

  • Lee, Young-Ki;Choi, Jea-Hoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.23 no.4
    • /
    • pp.441-448
    • /
    • 2012
  • This paper proposes a multiband Multi-Input Multi-output(MIMO) antenna for universal serial bus(USB) dongle application. The proposed MIMO antenna consists of a modified meander strip line and inverted L stub. The two radiating elements of the MIMO antenna are symmetrically placed with respect to the center of the ground plane. The fabricated antenna satisfied a VSWR below 3 and an efficiency over 35 % in the LTE band 13, 17(704 MHz-787 MHz), DCS/PCS/WCDMA band(1.71 GHz-2.17 GHz), and LTE band 7(2.5 GHz-2.7 GHz). The envelope correlation coefficient(ECC) has below 0.45 in the LTE band 13, 17 and 0.1 in the DCS/PCS/WCDMA band and LTE band 7, respectively.

A Study on the Characteristics change of WSix Thin Films by S/H Life Time (S/H Life Time에 따른 WSix의 특성 변화에 관한 연구)

  • 정양희;강성준
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.6 no.5
    • /
    • pp.689-695
    • /
    • 2002
  • Film compositions are needed in semiconductor manufacturing for such diverse application as production tool qualifications and process development. Surface and interface information is generally provided with Auger electron spectroscopy(AES). In this paper, WSix films were analyzed for structural, electrical, and compositional properties of tungsten silicide thin films produced by low pressure chemical vapor deposition as a function of temperature, DCS post flow, shower head life time, and the silicon to tungsten ratios have been investigated. We find that Si/W composition ratio is increased in the surface and interface of WSix thin films by the DCS post flow process and increasing deposition temperature, respectively. The results obtained in this study are also applicable to process control of WSix deposition for memory device fabrication.

Maturation and migration of dendritic cells upon stimulation with heat-killed tumor cells

  • Kim, Hyo-Jeong;Yoon, Taek-Joon;Lee, Sung-Won;Yun, Dae-Sun;Kim, Ji-Yeon;Shin, Kwang-Soon;Park, Se-Ho;Hong, Seok-Mann
    • Animal cells and systems
    • /
    • v.16 no.3
    • /
    • pp.215-223
    • /
    • 2012
  • Recently it has been reported that immunization with heat-killed tumor cells (HK vaccine) induces anti-tumor immune responses in mice. To investigate how HKvaccine elicits anti-tumor specific adaptive immunity, we examined the effect of HK vaccination on innate immune cells such as dendritic cells (DCs), which are essential for the generation of adaptive immunity. Upon stimulation with HK vaccine, DCs matured to promote not only the upregulation of co-stimulatory molecules but also secretion of cytokine IL12. Furthermore, HK vaccine-treated DCs migrated more efficiently to draining lymph nodes compared with untreated ones. Taken together, HK vaccine can be useful as an adjuvant to activate DCs for anti-tumor immune responses.

Association between Upper Extremity Musculoskeletal Disorders and Psychosocial Factors at Work: A Review on the Job DCS Model's Perspective

  • Park, Jung-Keun;Jang, Seung-Hee
    • Safety and Health at Work
    • /
    • v.1 no.1
    • /
    • pp.37-42
    • /
    • 2010
  • Over years it has been increasingly concerned with how upper extremity musculoskeletal disorders (UEMSDs) are attributed to psychosocial job stressors. A review study was conducted to examine associations between UEMSDs and psychosocial work factors, and to recommend what to consider for the associations. For studies in which the job demand-control-support (DCS) model or its variables were specifically employed, published papers were selected and reviewed. A number of studies have reported relationships between UEMSDs symptoms and psychosocial exposure variables. For example, the findings are: higher numbness in the upper extremity was significantly attributed to by less decision latitude at work; work demands were significantly associated with neck and shoulder symptoms while control over time was associated with neck symptoms; and the combination of high psychosocial demands and low decision latitude was a significant predictor for shoulder and neck pain in a female working population. Sources of bias, such as interaction or study design, were discussed. UEMSDs were shown to be associated with psychosocial work factors in various studies where the job DCS model was addressed. Nonetheless, this review suggests that further studies should be conducted to much more clarify the association between UEMSDs and psychosocial factors.