• Korean Journal of Biological Psychiatry
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• v.13 no.4
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• pp.260-266
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• 2006

Objectives : Synapsin III near VCFS region on chromosome 22q affects. It could be an interesting candidate gene for schizophrenia. D22S280 is a highly polymorphic genetic marker residing in synapsin III. We examined association of D22S280 marker on synapsin III with Korean patients with schizophrenia. Methods : The subjects were 46 male Korean patients with schizophrenia and 60 male normal controls. Using polymerase chain reaction, gel electrophoresis, ABI 310 genetic analyzer, and GeneScan Collection 3.1 software, we confirmed genotypes of D22S280 marker. We examined Hardy-Weinberg equilibrium and case-control association using SAS/Genetic 9.1.3. Results : Genotypes of both schizophrenia and control groups were in Hardy-Weinberg equilibrium. We could not find any significant statistical differences in allele-wise(${\chi}^2$=10.4, df=6, p=0.098) and genotype-wise (${\chi}^2$=22.1 df=19, p=0.258) analyses of D22S280 marker between schizophrenia and normal controls. Individual allele analyses with df=1 showed significant differences in A1(p=0.025) and A7(p=0.034) allele, which were not significant following Bonferroni corrections(A1:p=0.177, A7:p=0.235). Conclusion : We couldn't find any association between schizophrenia and the synapsin III gene. Given the small number of subjects studied, further investigations are needed.

• The Journal of the Korea Contents Association
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• v.9 no.11
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• pp.432-442
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• 2009

This research had a look at what effect of the pursing benefit has on satisfaction, behavioral intention, and attitude of the visitors to the Gwangju Biennale. The survey was conducted for 320 visitors who finished their exhibition viewing schedule starting September 5 until September 19 [15 days]. 300 questionnaires excepting 20 unfaithfully responded copies among those collected from the surveyed were used for the analysis. As for the statistical disposal of the collected data, after going through the process of Data Coding, this research conducted an frequency analysis using SPSS 12.0 for window & statistics package program AMOS 5.0, an exploratory factor analysis to test the reliability and feasibility of the data, and reliability test of each factor; then, this research tested a hypothesis using structural equation model. The research results are as follows: First, as a result of factor analysis of the 15 pursuing benefits, 4 factors were elicited, such as pursuit of an intellectual experience, pursuit of a novel, exotic experience, pursuit of interpersonal, cultural exchange, and pursuit of internal fullness, etc.; as a result of factor analysis of the 10 attitudes, three factors were elicited, such as affective, cognitive, behavioral factors; as a result of factor analysis of 12 types of satisfaction, two factors, such as satisfaction with facilities and convenience matters, etc. were elicited. Second, as a result of the suitability of research model, suitability, its fidelity came out as $x^2=107.508$, d.f.=48, p=.000, Q=2.240, GFI=.942, AGFI=.906, RMR=.024, NFI=.952, TLI=.963, CFI=.973, RMSEA=.064. Third, pursuing benefit was found out to have a positive effect on satisfaction, attitude, and behavioral intention. Fourth, attitude was found out to have a positive significant effect on satisfaction. Fifth, attitude was found out to have a positive effect on behavioral intention. Sixth, satisfaction was found out to have a positive effect on behavioral intention.

• Korean Journal of Environment and Ecology
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• v.30 no.2
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• pp.228-242
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• 2016

This research was conducted for understanding the evergreen forest community structure of the Bijin Island. The island was worth of vegetational value because of the representative warm temperate species such as Castanopsis cuspidata was distribute there. According to the results of community classification by TWINSPAN and DCA, the Bijin Island evergreen forest were classified by 9 communities, such as C. cuspidata, C. cuspidata-Pinus thunbergii, Neolitsea sericea-Camellia japonica, Platycarya strobilacea, Quercus serrata-Decidus broad-leaved, Alnus firma, P. thunbergii. Due to the C. cuspidata, N. sericea, Ca. japonica etc. were still dominated at canopy and under-canopy layer, so the evergreen forest will be sustain current conditions for a while if there is no artificial disturbances that were caused by human. Pl. strobilacea community will be expected to replace N. sericea and also Q. serrata-Decidus broad-leaved community will be changing caused by mutual competition. Normally, in the way of the succession process of the warm temperate forest, P. thunbergii will be expect via deciduous broad-leaved to evergreen forest such as Machilus thunbergii, C. cuspidata var. sieboldii, and N. sericea. In case of species diversity index, P. thunbergii comm.(1.2739), Q. serrata-Decidus broad-leaved comm.(1.2325), Decidus broad-leaved comm.(1.1807), and A. firma comm.(1.0854) are relatively high, while C. cuspidata and N. sericea-Ca. japonica that was dominated by evergreen species at canopy layer and P. thunbergii that was damaged by fire are relatively low(0.7380~0.8416). Soil pH was 4.72~6.33, electric conductance was 0.035~0.128dS/m, and content of organic matter was 3.4~17.4%.

• Wind and Structures
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• v.9 no.2
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• pp.125-146
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• 2006

Stonecutters Bridge of Hong Kong is a cable-stayed bridge with two single-column pylons each 298 m high and an aerodynamic twin deck. The total length of the bridge is 1596 m with a main span of 1018 m. The top 118 m of the tower will comprise structural steel and concrete composite while the bottom part will be of reinforced concrete. The bridge deck at the central span will be of steel whilst the side spans will be of concrete. Stonecutters Bridge has adopted a twin-girder deck design with a wide clear separation of 14.3 m between the two longitudinal girders. Although a number of studies have been conducted to investigate the aerodynamic performance of twin-girder deck, the actual real life application of this type of deck is extremely limited. This therefore triggered the need for conducting the present studies, the main objective of which is to investigate the performance of Stonecutters Bridge against flutter at its in-service stage as well as during construction. Based on the flutter derivatives obtained from the 1:80 scale rigid section model experiment, flutter analysis was carried out using 3-D finite element based single parameter searching method developed by the second author of this paper. A total of 6 finite element models of the bridge covering the in-service stage as well as 5 construction stages were established. The dynamic characteristics of the bridge associated with these stages were computed and applied in the analyses. Apart from the critical wind speeds for the onset of flutter, the dominant modes of vibration participating in the flutter vibration were also identified. The results indicate that the bridge will be stable against flutter at its in-service stage as well as during construction at wind speeds much higher than the verification wind speed of 95 m/s (1-minute mean).

• Korean Journal of Metals and Materials
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• v.47 no.4
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• pp.223-227
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• 2009

The precipitates, hardness, and tensile properties of Al-6.2Si-2.9Cu AC2B alloy were investigated with respect to solution treatment time at $500^{\circ}C$. $Al(Cu)-Al_2Cu$ eutectic, Si, ${\theta}-(Al_2Cu)$, and $Q-(Al_5Cu_2Mg_8Si_6)$ phases were observed in the as-cast specimen. With increasing the solution treatment time at $500^{\circ}C$, the $Al(Cu)-Al_2Cu$ eutectic and ${\theta}-(Al_2Cu)$ phases were gradually reduced and finally almost disappeared in 5 h. The mechanical properties, such as hardness, tensile strength, and elongation, were improved with solution treatment time until about 5 h due to the dissolution of the $Al_2Cu$ particles. With further holding time, the mechanical properties did not change much. The solution treated specimens for over 5 h at $500^{\circ}C$ exhibit almost the same tensile properties even after aging at $250^{\circ}C$ for 3.5 h. Accordingly, the optimal solution treatment condition of the Al-Si-Cu AC2B alloy is considered to be 5 h at $500^{\circ}C$.

• Applied Biological Chemistry
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• v.51 no.3
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• pp.171-176
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• 2008

The comparative molecular similarity indices analysis (CoMSIA) models between 3${\beta}$-Hydroxy-12-oleanen-28-oic acid (1-30) analogues as substrate molecule and their inhibitory activities ($pI_{50}$) against protein tyrosine phosphatase (PTP)-1B were derived and discussed quantitatively. Listing in order, the CoMFA>CoMSIA${\geq}$HQSAR>2D-QSAR model, these QSAR models had the better statistical values. The optimized CoMSIA F1 model at grid 3.0${\AA}$ had the best predictability and fitness ($q^2$=0.754 and $r^2$=0.976) by field fit alignment. The order of contribution ratio (%) of CoMSIA fields concerning the inhibitory activities was a H-bond acceptor (48.9%), steric field (25.8%) and hydrophobic field (25.4%), respectively. Therefore, the inhibitory activities of substrate molecules against PTP-1B were dependent upon H-bond acceptor field (A) of $R_4$-group. From the analytical results of CoMSIA contour maps, oleanolic acid derivatives will have better inhibition activities if $R_1$ group has H-bond acceptor disfavor, $R_3$group has steric disfavor and $R_4$ group has steric, hydrophobic, H-bond favor.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.12 no.1
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• pp.14-22
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• 2012

Objectives: This study was performed to review clinical manifestations of hyperphenylalaninemia patients in Korean. Methods: 178 cases of hyperphenyalaninemia were diagnosed at department of pediatrics, Soonchunhyang University Hospital from January, 1983 to August. We reviewed DNA analysis, MR imaging, EEG, radiography of the left hand and wrist, bone densitometry (BMD), IQ test of hyperphenyalaninemia patients. Results: Out of 178 cases, 161 cases were diagnosed classic phenylketonuria and 17 cases were diagnosed BH4 deficiency. 122 cases performed DNA analysis. R243Q (10.3%), Y204C (9.9%), and IVS4-1G>A (8.1%) mutations were predominant. 22 cases underwent MR imaging. Varying degrees of symmetrical high signal intensity were noted on T2-weighted sequences in the periventricular deep white matter of 15 cases. 23 cases were performed EEG. 12 cases (52.3%) showed abnormal pattern. EEG abnormalities showed in 11 cases. On lumbar BMD four of 11 cases (36%) showed reduced bone density of more than 1 S.D. in four of 11 cases, bone age was less than chronological age by at least one year. 18 cases were performed IQ test. Mean IQ scores was $84{\pm}21.6$. Among older than 15 years (9 cases), Mean IQ scores was $72{\pm}21.2$. PTPS deficiency was 14 cases, DHPR deficiency was 2 cases, and GTPCH deficiency was 1 case. Conclusion: We confirmed there were varieties of DNA mutations. And MR imaging and EEG were nonspecific in PKU patients. Older children showed lower IQ score. Low phenylalanine diet prevents brain damage in PKU patient. Not only first few years of life but also lifetime, Keeping low phenylalanine diet is important.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.9 no.3
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• pp.317-329
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• 1998

In this paper, we have analyzed the packet error probability of DS/CDMA-Trellis Coded QPSK modulation signal with MRC(Maximum Ratio Combining) diversity reception in Rician fading, multi-user interferences and multipath channel. And then we have evaluated the performance and capacity of DS/CDMA-Trellis Coded QPSK system using the MRC diversity reception as a function of direct power to indirect power ratio ($K_R$), the number of diversity branch(M), the number of multi-user(U), PN chip rate(PN), the number of multipath channel($L_P$), and packet length(PL). From the results, we know that the coding gain of DS/CDMA-Trellis Coded QPSK system with 2 branch MRC diversity is about 6 dB against uncoded DS/CDMA BPSK system with 2 branch MRC diversity in Rician fading ($K_R=6dB), 5 multi-user interferences, and 3 multipath channel. And, we know that coded QPSK signal designed for the AWGN channel also perform well on a Rician fading channel with MRC diversity reception. Consequently, we expected that proposed system structure is reliable to the wireless data communication system in Rician fading, multi-user interferences, and multipath channel.

• Journal of agriculture & life science
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• v.50 no.1
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• pp.105-115
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• 2016

This study was carried out to establish the optimum forest management plan for the Cryptomeria japonica plantations in southern inland and Jeju island in Korea. Sixty seven circular sample plots of 0.04ha were established and we surveyed vegetation structure and growth characteristics from three layers(upper, middle, and lower). As a result of cluster analysis obtained by importance values of each tree species, the community type of C. japonica stands were classified into C. japonica group(C1) and C. japonica-C obtusa group. C. obtusa community were also sbudivided into P. thunbergii-Q. serrata group(C2) and Q. serrata-C obtusa group(C3). In tree layers importance value(IV) of C. japonica were 97.2% in C1, 80.7% in C2, and 47.6% in C3 and in sub-tree layers IV were 8.9% in C1, 15.2% in C2, and 5.7% in C3. Especially in C3 there are bamboo species (Smilacina japonica var. lutecarpa and Pseudosasa japonica) it is necessary for us to control them. In shrub layers C. japonica were found in C1(9.2%) and C2(7.0%), but except for C3. In tree layer species diversity indices of each community ranged from the lowest 0.059 in C1 to the highest 0.548 in C3. Dominance ranged from 0.958 in C1 to 0.393 in C3 which may caused by interspecific competition. Current annual increment of diameter growth ranged from 7.01mm/yr to 8.04mm/yr. As a result of our study we recommend the application of proper thinning and pruning for C1 and C2.

• Journal of Korean Society of Forest Science
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• v.89 no.5
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• pp.618-629
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• 2000

This study was carried out to investigate ecological niche of Quercus acuta communities in Bogildo-island from July to October, 1998. This island is occupied by a subtropical evergreen broad-leaved forests. The study on community ecology of Q. acuta, mostly dominant species of subtropical forests, is very important for successful forest management. Sampling areas were selected in 16 quadrats, dominated by Q. acuta to examine the vegetation characteristics(plant identification, D.B.H.) and environmental elements (microtopography, altitude, slope degree, aspect, illumination and soil physicochemical properties). On the basis of data from field surveys, importance values were calculated for the dominance of Q. acuta and volume growth was analyzed by tree ring widths. The results obtained were as follows ; 1. The lists of vascular plants in the investigations were identified as 54 families, 91 genera, 113 species, 9 varieties, 1 formae. It appeared that 45 kinds were evergreen, 6 kinds(Camellia japonica, Ligustrum japonicum, Eurya japonica, Smilax china, Trachelospermum asiaticum var. intermedium, Carex lanceolata) were commonly observed in all plots and 5 species(Cinnamomum japonicum, Ardisia japonica, Cymbidium goeringii, Dryopteris bissetiana, Viburnum erosum) were most highly observed in all plots(over 80%). 2. The dominating species per strata were, Quercus acuta, Castanopsis cuspidata sp. Quercus salicina, Pinus thunbergii, Prunus sargentii in tree layer, Camellia Japonica, Ligustrum japonicum, Quercus acuta, Eurya japonica, Castanopsis cuspidata sp. in subtree layer, Camellia japonica, Ligustrum japonicum, Smilax china, Cinnamomum japonicum, Viburnum erosum in shrub layer and Trachelospermum asiaticum var. intermedium, Ardisia japonica, Carex lanceolata, Camellia japonica(seedlings), Quercus acuta(seedlings) in herb layer, all in descending orders. 3. Quercus acuta could be suggested as shade intolerant tree, considering the distribution in southern, western, nothern and eastern slopes in the descending orders. 4. Mean relative illumination in the forest is 0.89 % and it is relatively low in brightness. 5. Sustainment of Quercus acuta community couldn't be confirmed by judging from their reverse J curve in even-aged forest, as shown in D.B.H. distribution analysis. 6. The result of annual ring width analysis(mean ; 2.44 mm) showed three stages, such as a gentle increasing(1~12 year ; 2.04 mm), a relatively steep increasing(13~22 year ; 2.95 mm) and decreasing or stagnating(23 year after ; 2.41 mm).