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Phytochemical Constituents from the Aerial Part of Ducrosia ismaelis Asch.

  • Morgan, Abubaker M.A.;Kim, Jang Hoon;Lee, Hyun Woo;Lee, Sang-Hyun;Lim, Chi-Hwan;Jang, Hae-Dong;Kim, Young Ho
    • Natural Product Sciences
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    • v.21 no.1
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    • pp.6-13
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    • 2015
  • Phytochemical investigation of the aerial components of Ducrosia ismaelis Asch. led to the isolation of six known compounds, psoralen (1), isopsoralen (2), cnidioside A (3), (-)-syringaresinol-O-${\beta}$-D-glucopyranoside (4), (E)-plicatin B (5), trilinolein (6). The chemical structures of these compounds were elucidated from spectroscopic data and by comparison of these data with previously published results. The antioxidant, anti-osteoporotic and cardiovascular related activities of the isolated compounds were assessed using oxygen radical absorbance capacity (ORAC), reducing capacity, tartrate-resistant acid phosphatase (TRAP), and soluble epoxide hydrolase (sEH) inhibitory activity assays. Compounds (3-5) showed potent peroxyl radical-scavenging capacities with ORAC values of $11.06{\pm}0.39$, $7.98{\pm}0.10$, and $13.99{\pm}0.06$ Trolox equivalent (TE) at concentrations of $10{\mu}M$, respectively. Only compounds 4 and 5 was able to significantly reduce $Cu^{2+}$ ions, with a reduction value of $9.06{\pm}0.32$ and $4.61{\pm}0.00{\mu}M$ Trolox Equivalent (TE) at a concentration of $10{\mu}M$. Compound 5 at $10{\mu}M$ exhibited a potent inhibitory effect on osteoclastic TRAP activity with a TRAP value of $86.05{\pm}6.55%$ of the control. Compounds 1, 3 and 5 potently inhibited sEH activity with $IC_{50}$ values of 41.6 4.9, 16.0 1.1, and 49.0 $5.7{\mu}M$, respectively.

The Trapped Field Decay of YBCO Superconductor Composite with Times (시간 경과에 따른 YBCO 초전도 복합체의 포획 자기장 감쇄)

  • Lee, M.S.;Jang, G.E.;Jun, B.H.;Ha, D.W.;Son, M.H.;Han, Y.H.;Park, B.J.
    • Progress in Superconductivity
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    • v.12 no.2
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    • pp.82-87
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    • 2011
  • We studied the trapped field properties of bulk Y-Ba-Cu-O superconductors by applying 3 T of the permanent or $Nb_3Ti$ superconducting magnet. The 28 mm circular type of YBCO bulk superconductor was prepared and then hole at the center of bulk, parallel to the c-axis, was mechanically drilled. Typical size of hole in YBCO bulk was 10 mm in diameter. In order to examine the trapped field variation in terms of different impregnated materials, a hole in YBCO bulk was filled with resin and indium respectively. The trapped field decay due to flux flow was determined in terms of time. Our preliminary result indicates the trapped field value measured on the YBCO without hole after 30 minute by applying 3 T, was 6,500 G, which is much higher than that, 4,500 G, measured on YBCO with hole. Also, we confirmed that the tendency of a trapped field decrement with time was almost the same regardless of the impregnated materials in YBCO.

Formation of Retainted Austenite and Mechanical Properties of 4~8%Mn Hot Rolled TRIP Steels (4~8%Mn 열연 TRIP강의 잔류오스테나이트 생성과 기계적 성질)

  • Kim D. E.;Park Y. K.;Lee O. Y.;Jin K. G.;Kim S. J.
    • Korean Journal of Materials Research
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    • v.15 no.2
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    • pp.115-120
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    • 2005
  • The aim of this research is to develop the TRIP aided high strength low carbon steels using reverse transformation process. The $4\~8\%$ Mn steel sheets were reversely transformed by slow heating to intercritical temperature region and furnace cooling to room temperature. The stability of retained austenite depends on the enrichment of carbon and manganese by diffusion during the reverse transformation. The amount of retained austenite formed after reversely transformed at $625^{\circ}C$ for 6 hrs was about $50\;vol.\%$ in the $8\%Mn$ steel. The change in volume fraction of retained austenite with a holding temperature was consistent with the changes in elongation and the strength-ductility combination. The maximum strength-ductility combination of 40,000 $MPa{\cdot}\%$ was obtained when the $8\%Mn$ steel reversely transformed at $625^{\circ}C$ for 12 hrs. However, it's property was significantly decreased at higher holding temperature of $675^{\circ}C$ resulting from the decrease of ductility.

Detection of Genotype associated with Disease Activity and Development of Probe (질환활성과 관련된 유전자형 검색 및 탐색자 개발)

  • Lee, D.K.;Kim, K.J.;Kim, E.S.;Kim, J.H.;Yoo, S.K.;You, Y.O.;Kim, W.S.;Im, M.K.;Jang, S.I.
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.16 no.4
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    • pp.371-383
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    • 1994
  • 질환성과 관련된 세균의 분포 및 유전자형을 탐색하고자 구강농양 및 골수염의 급성감염 혼자와 진료실 및 실험실의 정상인을 대상으로 시료를 채취하여 포도상구균을 분리 및 동정을 시행하고, 특성을 규명하였으며, plasmid 및 염색유전자를 분리하여 제한효소를 처리후 전기영동을 실시하고 분리된 plasmid로 탐색자를 제작하여 dot blot을 시행하였다. 대부분의 급성환자에서 분리된 포도상구균을 S. lugdunensis와 S. aureus이었으나, 진료실 및 실험실에서는 coagulase 음성 staphylococci가 분리되었다. 급성환자에서 분리된 포도상구균은 ampicillin과 penicillin에 내성을 보였다. 분리된 S. lugdunensis균주중 네 균주는 ${\delta}$형의 용혈소를 생산하였다. Plasmid를 분리한 결과 S. lugdunensis균주중 세 균주는 약 6.5 kilobases이었으나 S. aureus는 약 4.3 kilobases 정도 크기의 band를 보였다. S. lugdunensis에서 분리된 plasmid로 제작한 탐색자로 dot blot를 시행한 결과 치과 영역에서 분리한 plasmid를 갖는 균주는 양성반응을 보였다. 염색체유전자의 유전자형을 분석한 결과 ${\delta}$형의 용혈소를 생산한 네 균주의 S. lugdunensis는 유사한 유전자형을 보였다. 이러한 연구결과 질환의 진행에 S. lugdunensis가 중요한 역할을 하는 것으로 생각되고, 치과영역에 존재하는 plasmid는 공통적인 유전자 서열을 갖는 것으로 추정된다.

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A Study on the Relationships Between the chief Nurse′s Leadership style and the organizational climate of Hospitals (간호과장의 지도성 유형과 병원 조직풍토와의 관계)

  • 김영매;한상임
    • Journal of Korean Academy of Nursing
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    • v.5 no.1
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    • pp.79-86
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    • 1975
  • It had been thought the role of Nursing administrator was still not started along the right line in Korea because of the Lacking of full understanding and recognition of the real meaning of administrator's role, and because there are several Rinds of problems and difficulties in actual role. The present study is an attempt to clarify some existing relationships between the chief Nurse's Leadership style and the organizational climate of Hospitals. The problems of the study are specifically started as follows ; 1) What influence does the individual behavior have on the formation of the organizational climate of Hospital? 2) From what do the difference of climate arise? 3) How are the individual be heavier and organizational climate of Hospital measured ? In order to see the relationships or the interactions between the two factors, the chief nurse's Leadership style and organizational climate of hospital , the researcher has classified. He former into; 1) effective Leadership style. 2) initiating structure leader ship style. 3) Consideration structure Leadership style, and 4) ineffective Leadership style, and the latter in to. 1) open climate and 2) closed climate The Chief Nurses Leadership style has been. Classified into consideration-human relations approaches and initiating structure approaches according to L. B. D. Q by Hapin. Organizational climate of hospital has been classified into open-closed continuum according to O. C. H Q. by Hairpin and Croft. The results obtained are as follows : 1) The chief nurse's Leadership style is closer to Initiating structure Leadership style than Consideration structure lure Leadership style. 2) The organizational climate of hospital is closer to open climate than closed climate. 3) The chief nurse's Leadership sty]e and the organizational climate of hospital to not show any significant relations.

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Relationship Between Physical Properties and Compression Index for Marine Clay (해성점토의 물리적 특성과 압축지수의 상관성)

  • 김동후;김기웅;백영식
    • Journal of the Korean Geotechnical Society
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    • v.19 no.6
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    • pp.371-378
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    • 2003
  • The compression index of clay distributed in the west and south coast of the Korean Peninsula had been studied. Compression index was obtained from the conventional consolidation test, and was conducted accordingly to obtain the field virgin compression curve by means of Schmertmann's graphical correction. To examine a correlation closely between physical properties of soils($e_o$, LL, w) and compression index(Cc), linen. and non-linear regression analysis were employed based on the data collected from tests. The conclusions are as follows. The compression index obtained by means of Schmereann's graphical correction is about 1.16 times for the value of original oedometer test curve for U/D samples. Non-liner regression curve was preferable to establish a correlation equation rather than linear regression curve. All derived equations so far achieved have been summarized and given. However, linear equation is better for practical use so that part by part simplified linear equations were also suggested alternatively together with their own non-linear regression curve.

Influence of Water Potential in Potato Tuber on Decay Development by Bacterial Soft Rot Caused by Erwinia carotovora var. atroseptica (감자연부병 (Erwinia carotovora var. atroseptica)에 의한 감자괴경부패와 water potential 에 관한 연구)

  • Hahm Young Il
    • Korean journal of applied entomology
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    • v.23 no.4 s.61
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    • pp.242-246
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    • 1984
  • Results obtained from the experiment conducted to find out e relationships between tuber decay, and water potential and bruising in or on the tubers, are summerized as follows ; 1) When potato tubers were bruised or injected with bacterial inoculum, the tubers with high water potential rotted more easily than the tubers with low potential. A big difference in the development of decay between high and low water potential tubers was found. 2) In tubers injected with different levels of inoculum. high water potential tubers were more susceptible to soft rot than low water potential tubers. 3) $ED_{50}$ of inoculum concentration was 8.5(log) at high water potential tubers and 9.8(log) at low water potential. A small difference between low and high water potential was detected. The results of this experiment show that potatoes should be handled carefully and must be dried after harvest to reduce decay development in shipment and storage.

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Effect of Zirconia Core Thickness on the Tone Blocking of Discolored Tooth and Metal Post (지르코니아 코어의 두께에 따른 변색치와 메탈 포스트의 색조차단 효과)

  • O, Seon-Mi;Lee, Chae-Hyun
    • Journal of Technologic Dentistry
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    • v.32 no.4
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    • pp.327-335
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    • 2010
  • Purpose: The purpose of this study was to investigate the correlation between zirconia core thickness and color tone blocking of discolored tooth and metal post. Methods: For this study, we made 20-porcelain sample and 4-metal sample( liechtenstein IPS e.max) bonded to zirconia core of different thickness with cement(Relyx ARC-3M USA)for produce discolored. We measured the color-spectral characteristics, using Shadepilot equipment(Degudent USA).We measured it with Shadepilot equipment set by automated average mode in 3 times And applied the average value obtained from 2 times of measurement in the middle of each sample. Results: As a result of analysing color-spectral characteristics on zirconia core sample, Depending on the thickness of zirconia core, the value of brightness(${\Delta}L*$:color-spectral characteristic) was increased within limited range, value of ${\Delta}a*$, ${\Delta}b*$ was decrease. Conclusion: Consequently, we obtained the following results: Changes of sample color were observed depending on the thickness of zirconia, but the range of change did not exceed the scope range of shade guide. The case of metal posts, shade guide color D2 were observed in 0.5mm of zirconia core thickness. As a result, in case of porcelain, increasing the zirconia thickness of 0.3mm or more is unnecessary for color blocking effect, in case of metal post, considering the discolored tooth, thickness of zirconia with at least 0.5mm or more is recommended.

Development of Eddy Current Test Probe for Profilometry Inspection of Tube (원형튜브 단면형상검사용 와전류탐촉자 개발)

  • Lee, H.J.;Nam, M.W.;Lee, C.H.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.17 no.4
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    • pp.262-269
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    • 1997
  • An eddy current probe ($8{\times}1$ multiple-element, surface scan) was successfully designed and fabricated at the KEPRI using the impedance equivalent circuit theory. The probe is intended for the detection of circumferential deformations (cross-section view) of the heat exchanger tubing that can occur due to corrosion, erosion, and denting. Optimum design parameters providing the highest sensitivity and signal-to-noise ratio, such as the coil dimensions, electrical characteristics, and test frequencies, were determined based on initial laboratory experiments conducted on the test specimen (SS304 tubing: OD : 9.68mm, wall-thickness : 0.47mm) containing artificial flaws (e.g., dents and corroded surface on tube OD) using the available Zetec-made probe. Using this parameters, a new probe was made and tested on an unknown specimen. The result indicated that the new probe is capable of detecting the circumferential deformation with the error of ${\pm}0.2%$ (0.022mm) of the tube O.D.

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Three-dimensional FE analysis of headed stud anchors exposed to fire

  • Ozbolt, Josko;Koxar, Ivica;Eligehausen, Rolf;Periskic, Goran
    • Computers and Concrete
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    • v.2 no.4
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    • pp.249-266
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    • 2005
  • In the present paper a transient three-dimensional thermo-mechanical model for concrete is presented. For given boundary conditions, temperature distribution is calculated by employing a three-dimensional transient thermal finite element analysis. Thermal properties of concrete are assumed to be constant and independent of the stress-strain distribution. In the thermo-mechanical model for concrete the total strain tensor is decomposed into pure mechanical strain, free thermal strain and load induced thermal strain. The mechanical strain is calculated by using temperature dependent microplane model for concrete (O$\check{z}$bolt, et al. 2001). The dependency of the macroscopic concrete properties (Young's modulus, tensile and compressive strengths and fracture energy) on temperature is based on the available experimental database. The stress independent free thermal strain is calculated according to the proposal of Nielsen, et al. (2001). The load induced thermal strain is obtained by employing the biparabolic model, which was recently proposed by Nielsen, et al. (2004). It is assumed that the total load induced thermal strain is irrecoverable, i.e., creep component is neglected. The model is implemented into a three-dimensional FE code. The performance of headed stud anchors exposed to fire was studied. Three-dimensional transient thermal FE analysis was carried out for three embedment depths and for four thermal loading histories. The results of the analysis show that the resistance of anchors can be significantly reduced if they are exposed to fire. The largest reduction of the load capacity was obtained for anchors with relatively small embedment depths. The numerical results agree well with the available experimental evidence.